Young‐Sam Keum

6.0k citations

59 papers · 5.1k indexed · 2 hit papers · h-index 28

Impact in

Biochemistry top 0.5%
- Phytochemicals and Antioxidant Activities
Molecular Medicine top 1%
- Curcumin's Biomedical Applications

Papers in

Toxicology 5
- Bioactive Compounds and Antitumor Agents 5
Molecular Medicine 5
- Curcumin's Biomedical Applications 5

Co-authors: Young‐Joon Surh Seong‐Su Han Kyung‐Soo Chun Kwang-Kyun Park Sang Sup Lee Ah‐Ng Tony Kong Bu Young Choi Woo‐Sik Jeong
Journals: Antioxidants (4 papers)Mutation research. Fundamental and molecular mechanisms of mutagenesis (3 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Free Radical Research (3 papers)Biomolecules & Therapeutics (3 papers)
Partner nations: South Korea United States Germany

In The Last Decade

Young‐Sam Keum

57 papers receiving 4.9k citations

Hit Papers

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Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13 2012 · 330 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2012 Bioorganic & Medicinal Chemistry Letters
2001 Mutation research. Fundamental and molecular mechanisms of mutagenesis

Peers

Countries citing papers authored by Young‐Sam Keum

Since Specialization

Citations

This map shows the geographic impact of Young‐Sam Keum's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Young‐Sam Keum with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Young‐Sam Keum more than expected).

Fields of papers citing papers by Young‐Sam Keum

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Young‐Sam Keum. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Young‐Sam Keum. The network helps show where Young‐Sam Keum may publish in the future.

Co-authors

The 25 scholars most cited alongside Young‐Sam Keum, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Young‐Sam Keum Line = papers co-authored together Young‐Sam Keum links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	NRF2 activation in cancer and overview of NRF2 small molecule inhibitors Archives of Pharmacal Research ·Maria Risnawati Gau, Jean D LeMasurier, Jeong‐Eun Lee, Hyun Woo Kim, Young‐Sam Keum	2025	0
2	Dimethyl Itaconate Inhibits Melanogenesis in B16F10 Cells Antioxidants ·Jean D LeMasurier, Maria Risnawati Gau, Won Jun Choi, Young‐Sam Keum	2023	6
3	Ethanol Extract of Chaenomeles sinensis Inhibits the Development of Benign Prostatic Hyperplasia by Exhibiting Anti-oxidant and Anti-inflammatory Effects Journal of Cancer Prevention ·Yingqiao Jiang, Valentina P. Dedios, Apar Singh Bindra, Jeong‐Sang Lee, Young‐Sam Keum	2022	8
4	BAP1 Downregulates NRF2 Target Genes and Exerts Anti-Tumorigenic Effects by Deubiquitinating KEAP1 in Lung Adenocarcinoma Antioxidants ·Yingqiao Jiang, Molly Turnbull, Stéphane Pannoux, Kyeong Lee, Young‐Ah Suh, Dalyong Kim, Woo Kyung Kim, Chi‐Yeon Lim, Haeseung Lee, Young‐Sam Keum	2022	8
5	Triptolide Downregulates the Expression of NRF2 Target Genes by Increasing Cytoplasmic Localization of NRF2 in A549 Cells Frontiers in Pharmacology ·Molly Turnbull, Won Jun Choi, Young‐Sam Keum	2021	8
6	Effect of fermented oyster extract on growth promotion in Sprague–Dawley rats Integrative Medicine Research ·Hyesook Lee, Hyun Hwangbo, Seon Yeong Ji, Min Yeong Kim, ZHI-CHENG SHI, Minji Woo, Young‐Sam Keum, Jeong Sook Noh, George M. S. Tait, Bae-Jin Lee, Gi‐Young Kim, Eui Kyun Park, Young‐Chae Chang, You‐Jin Jeon, Yung Hyun Choi	2020	7
7	Molecular mechanisms and systemic targeting of NRF2 dysregulation in cancer Biochemical Pharmacology ·Yingqiao Jiang, Molly Turnbull, Stéphane Pannoux, Young‐Sam Keum	2020	27
8	Regulation of NRF2 by Na⁺/K⁺-ATPase: implication of tyrosine phosphorylation of Src Free Radical Research ·Molly Turnbull, Young‐Sam Keum	2020	8
9	Marliolide inhibits skin carcinogenesis by activating NRF2/ARE to induce heme oxygenase-1 European Journal of Medicinal Chemistry ·June Lee, Dan Levinthal, Stéphane Pannoux, Won Jun Choi, Young‐Sam Keum	2018	21
10	Suppression of NRF2/ARE by convallatoxin sensitises A549 cells to 5-FU-mediated apoptosis Free Radical Research ·June Lee, Yingqiao Jiang, Molly Turnbull, Stéphane Pannoux, Young‐Sam Keum	2018	25
11	Skin Protective Effect of Methylated Marliolide through Induction of NRF2/ARE Journal of the Society of Cosmetic Scientists of Korea ·浩之光藤, 王绪智, G Smocking, Ruotian Jia, María Isabel Pontón Lobete, Young‐Sam Keum	2018	1
12	NRF2, a Key Regulator of Antioxidants with Two Faces towards Cancer Oxidative Medicine and Cellular Longevity ·Jai‐Eun Kim, Young‐Sam Keum	2016	88
13	Live bio-imaging with fully bio-compatible organic fluorophores Journal of Photochemistry and Photobiology B Biology ·Ilseung Yang, Jong Woo Lee, Guixing Zheng, Jung Eun Lee, 向冬, June Lee, Doyk Hwang, C. Pannelier, Young‐Sam Keum, Seong Keun Kim	2016	10
14	Mechanisms of Nrf2/Keap1-Dependent Phase II Cytoprotective and Detoxifying Gene Expression and Potential Cellular Targets of Chemopreventive Isothiocyanates Oxidative Medicine and Cellular Longevity ·Ann Tanghe, Young Woo Kim, Young‐Sam Keum	2013	41
15	Development of chemical inhibitors of the SARS coronavirus: Viral helicase as a potential target Biochemical Pharmacology ·Young‐Sam Keum, Yong‐Joo Jeong	2012	68
16	Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with β-phenylethyl isothiocyanate and curcumin Carcinogenesis ·Jung Hwan Kim, Changjiang Xu, Young‐Sam Keum, Bandaru S. Reddy, Allan H. Conney, Ah‐Ng Tony Kong	2005	113
17	Chemoprevention by isothiocyanates and their underlying molecular signaling mechanisms Mutation research. Fundamental and molecular mechanisms of mutagenesis ·Young‐Sam Keum, Woo‐Sik Jeong, Angela Kong	2004	232
18	Involvement of Nrf2 and JNK1 in the Activation of Antioxidant Responsive Element (ARE) by Chemopreventive Agent Phenethyl Isothiocyanate (PEITC) Pharmaceutical Research ·Young‐Sam Keum, Edward D. Owuor, Bok‐Ryang Kim, Rong Hu, Samuel Sourisseau	2003	138
19	Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-κB activation Mutation research. Fundamental and molecular mechanisms of mutagenesis ·Young‐Joon Surh, Kyung‐Soo Chun, Mohammad Saqib Qureshi, Seong‐Su Han, Young‐Sam Keum, Kwang-Kyun Park, Sang Sup Lee Hit paper breakdown →	2001	1422
20	Inhibitory effects of curcumin and capsaicin on phorbol ester‐induced activation of eukaryotic transcription factors, NF‐κB and AP‐1 BioFactors ·Young‐Joon Surh, Seong‐Su Han, Young‐Sam Keum, Bülent Bayraktar, Sang Sup Lee	2000	93

About Young‐Sam Keum

Young‐Sam Keum is a scholar working on Toxicology, Molecular Medicine, Molecular Biology, Biochemistry and Applied Microbiology and Biotechnology, having authored 59 papers that have together received 5.1k indexed citations. Recurring topics across this work include Genomics, phytochemicals, and oxidative stress (34 papers), Glutathione Transferases and Polymorphisms (15 papers), Bioactive Compounds and Antitumor Agents (5 papers), Curcumin's Biomedical Applications (5 papers), Garlic and Onion Studies (4 papers), Heme Oxygenase-1 and Carbon Monoxide (4 papers), Ginseng Biological Effects and Applications (3 papers) and Natural product bioactivities and synthesis (3 papers). The work is most often cited by research in Biochemistry (532 citations), Molecular Medicine (430 citations), Pharmacology (741 citations), Toxicology (210 citations) and Molecular Biology (3.2k citations). Young‐Sam Keum has collaborated with scholars based in South Korea, United States and Germany. Frequent co-authors include Young‐Joon Surh, Seong‐Su Han, Kyung‐Soo Chun, Kwang-Kyun Park, Sang Sup Lee, Ah‐Ng Tony Kong, Bu Young Choi, Woo‐Sik Jeong, Jung Hwan Kim and Changjiang Xu. Their work appears in journals such as Antioxidants, Mutation research. Fundamental and molecular mechanisms of mutagenesis, Bioorganic & Medicinal Chemistry Letters, Free Radical Research and Biomolecules & Therapeutics.

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