Yasushi Saeki

11.5k total citations · 3 hit papers
109 papers, 8.6k citations indexed

About

Yasushi Saeki is a scholar working on Molecular Biology, Cell Biology and Epidemiology. According to data from OpenAlex, Yasushi Saeki has authored 109 papers receiving a total of 8.6k indexed citations (citations by other indexed papers that have themselves been cited), including 102 papers in Molecular Biology, 37 papers in Cell Biology and 24 papers in Epidemiology. Recurrent topics in Yasushi Saeki's work include Ubiquitin and proteasome pathways (89 papers), Endoplasmic Reticulum Stress and Disease (30 papers) and Autophagy in Disease and Therapy (23 papers). Yasushi Saeki is often cited by papers focused on Ubiquitin and proteasome pathways (89 papers), Endoplasmic Reticulum Stress and Disease (30 papers) and Autophagy in Disease and Therapy (23 papers). Yasushi Saeki collaborates with scholars based in Japan, Germany and United States. Yasushi Saeki's co-authors include Keiji Tanaka, Hikaru Tsuchiya, Akio Toh‐e, Hideyoshi Yokosawa, Fumiaki Ohtake, Kazuhiro Iwaï, Noriyuki Matsuda, Kei Okatsu, Tomoko Nakagawa and Fumika Koyano and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Yasushi Saeki

103 papers receiving 8.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Ubiquitin is phosphorylated by PINK1 to activate parkin

2014 1.1k citations Yasushi Saeki, Keiji Tanaka et al. profile →
Involvement of linear polyubiquitylation of NEMO in NF-κB activation

2009 742 citations Fuminori Tokunaga, Yasushi Saeki et al. profile →
Mutations in the deubiquitinase gene USP8 cause Cushing's disease

2014 405 citations Martín Reincke, Silviu Sbiera et al. Nature Genetics profile →

Peers

Countries citing papers authored by Yasushi Saeki

Since Specialization

Citations

This map shows the geographic impact of Yasushi Saeki's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yasushi Saeki with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yasushi Saeki more than expected).

Fields of papers citing papers by Yasushi Saeki

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yasushi Saeki. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yasushi Saeki. The network helps show where Yasushi Saeki may publish in the future.

Co-authorship network of co-authors of Yasushi Saeki

This figure shows the co-authorship network connecting the top 25 collaborators of Yasushi Saeki. A scholar is included among the top collaborators of Yasushi Saeki based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yasushi Saeki. Yasushi Saeki is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	TanGIBLE: A selective probe for evaluating hydrophobicity-exposed defective proteins in live cells 2025 ·The Journal of Cell Biology ·Yasushi Iwasa, Shiro Miyata, Takuya Tomita, (unknown), (unknown), (unknown), (unknown), Rigel Suzuki, Yasushi Saeki, Hiroyuki Kawahara	1
2	Polyubiquitin architecture editing on collided ribosomes maintains persistent RQC activity 2025 ·The EMBO Journal ·(unknown), Yoshitaka Matsuo, Fumiaki Ohtake, Takuya Tomita, Yasushi Saeki, Toshifumi Inada	0
3	Ribosomal S6 kinase (RSK) plays a critical role in DNA damage response via the phosphorylation of histone lysine demethylase KDM4B 2024 ·Breast Cancer Research ·Wenwen Wu, Jing Zhu, Naoe Taira Nihira, (unknown), (unknown), Junki Koike, Kiyoshi Yamaguchi, Yoichi Furukawa, Takuya Tomita, Yasushi Saeki, Yoshikazu Johmura, Makoto Nakanishi, Yasuo Miyoshi, Tomohiko Ohta	2
4	USP8 prevents aberrant NF-κB and Nrf2 activation by counteracting ubiquitin signals from endosomes 2024 ·The Journal of Cell Biology ·Akinori Endo, Toshiaki Fukushima, (unknown), H. Tsuchiya, Fumiaki Ohtake, Sayaka Ono, Tony Ly, Yukiko Yoshida, Keiji Tanaka, Yasushi Saeki, Masayuki Komada	7
5	Intrinsic signaling pathways modulate targeted protein degradation 2024 ·Nature Communications ·(unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Masakazu Kato, (unknown), Yasushi Saeki, Jun Hamazaki, Shigeo Murata, Toshikazu Ushijima, Naoko Hattori, Fumiaki Ohtake	10
6	The TGN/EE SNARE protein SYP61 and the ubiquitin ligase ATL31 cooperatively regulate plant responses to carbon/nitrogen conditions in Arabidopsis 2022 ·The Plant Cell ·Yoko Hasegawa, Thais Huarancca Reyes, Tomohiro Uemura, (unknown), (unknown), (unknown), (unknown), Yasushi Saeki, Shugo Maekawa, Shigetaka Yasuda, (unknown), Yoichiro Fukao, Keiji Tanaka, Akihiko Nakano, Junpei Takagi, Rishikesh P. Bhalerao, Junji Yamaguchi, Takeo Sato	20
7	MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL 2021 ·Communications Biology ·Osamu Nakabayashi, Hirotaka Takahashi, Kenta Moriwaki, Sachiko Komazawa‐Sakon, Fumiaki Ohtake, Shin Murai, Yuichi Tsuchiya, (unknown), Yasushi Saeki, Yukiko Yoshida, Soh Yamazaki, Fuminori Tokunaga, Tatsuya Sawasaki, Hiroyasu Nakano	19
8	RNA polymerase II condensate formation and association with Cajal and histone locus bodies in living human cells 2021 ·Genes to Cells ·(unknown), Takeshi Shimi, Ai Kaiho, Yasushi Saeki, Hiroshi Kimurâ	14
9	RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1 2020 ·Nature Structural & Molecular Biology ·Yoshitaka Matsuo, Petr Těšina, (unknown), (unknown), Akinori Endo, Robert Buschauer, Jingdong Cheng, (unknown), Ken Ikeuchi, Yasushi Saeki, Thomas Becker, Roland Beckmann, Toshifumi Inada	105
10	Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses 2020 ·Communications Biology ·Daisuke Oikawa, Yusuke Sato, Fumiaki Ohtake, (unknown), (unknown), Koji Sugawara, Seigo Terawaki, (unknown), (unknown), Kiyosei Iio, Shingo Obika, Masaya Fukushi, Takashi Irie, Daisuke Tsuruta, S. Sakamoto, Keiji Tanaka, Yasushi Saeki, Shuya Fukai, Fuminori Tokunaga	39
11	Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation 2020 ·Nature Communications ·Atsuya Nishiyama, Christopher B. Mulholland, Sebastian Bultmann, (unknown), Akinori Endo, Yasushi Saeki, Weihua Qin, (unknown), Yoshie Chiba, (unknown), Soichiro Kumamoto, Toru Kawakami, Hironobu Hojo, Genta Nagae, Hiroyuki Aburatani, Keiji Tanaka, Kyohei Arita, Heinrich Leonhardt, Makoto Nakanishi	96
12	Collided ribosomes form a unique structural interface to induce Hel2‐driven quality control pathways 2019 ·The EMBO Journal ·Ken Ikeuchi, Petr Těšina, Yoshitaka Matsuo, Takato Sugiyama, Jingdong Cheng, Yasushi Saeki, Keiji Tanaka, Thomas Becker, Roland Beckmann, Toshifumi Inada	216
13	HERC2 Facilitates BLM and WRN Helicase Complex Interaction with RPA to Suppress G-Quadruplex DNA 2018 ·Cancer Research ·Wenwen Wu, Nana Rokutanda, (unknown), Yongqiang Lai, Reo Maruyama, (unknown), Hiroyuki Nishikawa, Naoko Arai, Yasuo Miyoshi, Nao Suzuki, Yasushi Saeki, Keiji Tanaka, Tomohiko Ohta	47
14	Ubiquitination of exposed glycoproteins by SCF FBXO27 directs damaged lysosomes for autophagy 2017 ·Yukiko Yoshida, Sayaka Yasuda, (unknown), Maho Hamasaki, Arisa Murakami, Junko Kawawaki, Kazuhiro Iwaï, Yasushi Saeki, Tamotsu Yoshimori, Noriyuki Matsuda, Keiji Tanaka	9
15	Mutations in the deubiquitinase gene USP8 cause Cushing's disease breakdown → 2014 ·Nature Genetics ·Martín Reincke, Silviu Sbiera, Akira Hayakawa, Marily Theodoropoulou, Andrea Oßwald, Felix Beuschlein, Thomas Meitinger, (unknown), Kohei Kawaguchi, Yasushi Saeki, Keiji Tanaka, Thomas Wieland, Elisabeth Graf, Wolfgang Saeger, Cristina L. Ronchi, Bruno Allolio, Michael Buchfelder, Tim M. Strom, Martin Faßnacht, Masayuki Komada	405
16	Structural Basis for Specific Recognition of Rpt1p, an ATPase Subunit of 26 S Proteasome, by Proteasome-dedicated Chaperone Hsm3p 2012 ·Journal of Biological Chemistry ·Kenji Takagi, Sangwoo Kim, (unknown), (unknown), Ryo Morishita, Yaeta Endo, Koichi Kato, Keiji Tanaka, Yasushi Saeki, Tsunehiro Mizushima	29
17	Proteasomal Degradation Resolves Competition between Cell Polarization and Cellular Wound Healing 2012 ·Cell ·Keiko Kono, Yasushi Saeki, Satoshi Yoshida, Keiji Tanaka, David Pellman	82
18	Polyubiquitin conjugation to NEMO by triparite motif protein 23 (TRIM23) is critical in antiviral defense 2010 ·Proceedings of the National Academy of Sciences ·Kei‐ichiro Arimoto, Kenji Funami, Yasushi Saeki, Keiji Tanaka, Katsuya Okawa, Osamu Takeuchi, Shizuo Akira, Yoshiki Murakami, Kunitada Shimotohno	141
19	Sem1p Is a Novel Subunit of the 26 S Proteasome from Saccharomyces cerevisiae 2004 ·Journal of Biological Chemistry ·(unknown), Yasushi Saeki, Akio Toh‐e, Hideyoshi Yokosawa	113
20	Identification of ubiquitin-like protein-binding subunits of the 26S proteasome 2002 ·Biochemical and Biophysical Research Communications ·Yasushi Saeki, (unknown), Akio Toh‐e, Hideyoshi Yokosawa	109

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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