Tsunehiro Mizushima

8.0k total citations · 3 hit papers
60 papers, 5.5k citations indexed

About

Tsunehiro Mizushima is a scholar working on Molecular Biology, Cell Biology and Oncology. According to data from OpenAlex, Tsunehiro Mizushima has authored 60 papers receiving a total of 5.5k indexed citations (citations by other indexed papers that have themselves been cited), including 52 papers in Molecular Biology, 15 papers in Cell Biology and 14 papers in Oncology. Recurrent topics in Tsunehiro Mizushima's work include Ubiquitin and proteasome pathways (30 papers), Glycosylation and Glycoproteins Research (17 papers) and Endoplasmic Reticulum Stress and Disease (13 papers). Tsunehiro Mizushima is often cited by papers focused on Ubiquitin and proteasome pathways (30 papers), Glycosylation and Glycoproteins Research (17 papers) and Endoplasmic Reticulum Stress and Disease (13 papers). Tsunehiro Mizushima collaborates with scholars based in Japan, United Kingdom and United States. Tsunehiro Mizushima's co-authors include Keiji Tanaka, Tomitake Tsukihara, Kenji Takagi, Masaaki Komatsu, Yu‐shin Sou, Yoshinobu Ichimura, Takashi Yamane, Eiki Yamashita, Masayuki Yamamoto and Toshiaki Fukutomi and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Tsunehiro Mizushima

59 papers receiving 5.4k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

2013 950 citations Yoshinobu Ichimura, Yu‐shin Sou et al. profile →
Redox-Coupled Crystal Structural Changes in Bovine Heart Cytochrome c Oxidase

1998 862 citations Eiki Yamashita, Tsunehiro Mizushima et al. profile →
Structural Basis for Sorting Mechanism of p62 in Selective Autophagy

2008 642 citations Yoshinobu Ichimura, Taichi Kumanomidou et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Tsunehiro Mizushima Japan	29	4.2k	1.5k	1.1k	539	502	60	5.5k
Frank Löhr Germany	41	4.3k 1.0×	1.2k 0.8×	768 0.7×	436 0.8×	268 0.5×	150	6.1k
Gary S. Shaw Canada	41	4.2k 1.0×	1.0k 0.7×	430 0.4×	632 1.2×	552 1.1×	153	5.5k
Bradley J. Backes United States	30	2.9k 0.7×	871 0.6×	1.4k 1.3×	588 1.1×	450 0.9×	45	5.0k
Janet Finer-Moore United States	38	4.6k 1.1×	720 0.5×	1.1k 1.0×	843 1.6×	330 0.7×	97	6.4k
Chris Meisinger Germany	63	11.3k 2.7×	1.1k 0.7×	1.4k 1.2×	383 0.7×	250 0.5×	119	12.5k
Ching‐Shih Chen United States	44	4.7k 1.1×	521 0.4×	651 0.6×	1.0k 1.9×	616 1.2×	144	6.8k
Bernard Guiard France	68	11.8k 2.8×	585 0.4×	1.4k 1.3×	237 0.4×	243 0.5×	156	12.6k
Matthieu Schapira Canada	46	8.2k 2.0×	969 0.7×	2.0k 1.8×	1.1k 2.0×	559 1.1×	114	10.4k
Xiaolan Zhao United States	38	6.0k 1.4×	466 0.3×	1.1k 1.0×	1.4k 2.6×	176 0.4×	132	7.3k
John E. Burke Canada	45	4.1k 1.0×	472 0.3×	1.2k 1.1×	500 0.9×	597 1.2×	127	5.8k

Countries citing papers authored by Tsunehiro Mizushima

Since Specialization

Citations

This map shows the geographic impact of Tsunehiro Mizushima's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tsunehiro Mizushima with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tsunehiro Mizushima more than expected).

Fields of papers citing papers by Tsunehiro Mizushima

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tsunehiro Mizushima. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tsunehiro Mizushima. The network helps show where Tsunehiro Mizushima may publish in the future.

Co-authorship network of co-authors of Tsunehiro Mizushima

This figure shows the co-authorship network connecting the top 25 collaborators of Tsunehiro Mizushima. A scholar is included among the top collaborators of Tsunehiro Mizushima based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tsunehiro Mizushima. Tsunehiro Mizushima is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Suzuki, Takafumi, Kenji Takagi, Tatsuro Iso, et al.. (2025). Bidirectional regulation of KEAP1 BTB domain-based sensor activity. Redox Biology. 87. 103885–103885.

Satoh, Tadashi, Maho Yagi‐Utsumi, Nozomi Ishii, et al.. (2024). Structural basis of sugar recognition by SCF ^FBS2 ubiquitin ligase involved in NGLY1 deficiency. FEBS Letters. 598(18). 2259–2268. 2 indexed citations

Sugiura, Yuki, Shunsuke Matsumoto, Yuki Takano, et al.. (2023). Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Science Advances. 9(15). eadf1956–eadf1956. 7 indexed citations

Suzuki, Takafumi, Jin Inoue, Tatsuro Iso, et al.. (2021). Molecular basis for the disruption of Keap1–Nrf2 interaction via Hinge & Latch mechanism. Communications Biology. 4(1). 576–576. 135 indexed citations

Satoh, Tadashi, et al.. (2020). Crystallographic snapshots of the EF-hand protein MCFD2 complexed with the intracellular lectin ERGIC-53 involved in glycoprotein transport. Acta Crystallographica Section F Structural Biology Communications. 76(5). 216–221. 6 indexed citations

Tezuka, Tohru, Minsoo Kim, Jung-Mi Choi, et al.. (2020). Moyamoya disease patient mutations in the RING domain of RNF213 reduce its ubiquitin ligase activity and enhance NFκB activation and apoptosis in an AAA+ domain-dependent manner. Biochemical and Biophysical Research Communications. 525(3). 668–674. 37 indexed citations

Matsuda, Noriyuki, Mayumi Kimura, Bruno B. Queliconi, et al.. (2017). Parkinson’s disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro. Scientific Reports. 7(1). 12816–12816. 47 indexed citations

Takagi, Kenji, Minsoo Kim, Chihiro Sasakawa, & Tsunehiro Mizushima. (2016). Crystal structure of the substrate-recognition domain of theShigellaE3 ligase IpaH9.8. Acta Crystallographica Section F Structural Biology Communications. 72(4). 269–275. 11 indexed citations

Kumanomidou, Taichi, Kenji Takagi, Tomomi Nakagawa, et al.. (2015). The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3. PLoS ONE. 10(10). e0140366–e0140366. 14 indexed citations

10.

Satoh, Tadashi, Yasushi Saeki, Takeshi Hiromoto, et al.. (2014). Structural Basis for Proteasome Formation Controlled by an Assembly Chaperone Nas2. Structure. 22(5). 731–743. 25 indexed citations

11.

Uekusa, Yoshinori, Keisuke Okawa, Maho Yagi‐Utsumi, et al.. (2013). Backbone 1H, 13C, and 15N assignments of yeast Ump1, an intrinsically disordered protein that functions as a proteasome assembly chaperone. Biomolecular NMR Assignments. 8(2). 383–386. 15 indexed citations

12.

Kobayashi, T., Michinaga Ogawa, Takahito Sanada, et al.. (2013). The Shigella OspC3 Effector Inhibits Caspase-4, Antagonizes Inflammatory Cell Death, and Promotes Epithelial Infection. Cell Host & Microbe. 13(5). 570–583. 158 indexed citations

13.

Kim, Minsoo, et al.. (2013). Structural Basis for the Recognition of Ubc13 by the Shigella flexneri Effector OspI. Journal of Molecular Biology. 425(15). 2623–2631. 24 indexed citations

14.

Takagi, Kenji, Sangwoo Kim, Ryo Morishita, et al.. (2012). Structural Basis for Specific Recognition of Rpt1p, an ATPase Subunit of 26 S Proteasome, by Proteasome-dedicated Chaperone Hsm3p. Journal of Biological Chemistry. 287(15). 12172–12182. 29 indexed citations

15.

Mizushima, Tsunehiro, Hirokazu Yagi, Shigeru Iida, et al.. (2011). Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans. Genes to Cells. 16(11). 1071–1080. 179 indexed citations

16.

Kim, Sangwoo, Yasushi Saeki, Keisuke Fukunaga, et al.. (2010). Crystal Structure of Yeast Rpn14, a Chaperone of the 19 S Regulatory Particle of the Proteasome. Journal of Biological Chemistry. 285(20). 15159–15166. 20 indexed citations

17.

Ichimura, Yoshinobu, Taichi Kumanomidou, Yu‐shin Sou, et al.. (2008). Structural Basis for Sorting Mechanism of p62 in Selective Autophagy. Journal of Biological Chemistry. 283(33). 22847–22857. 642 indexed citations breakdown →

18.

Kumanomidou, Taichi, Tsunehiro Mizushima, Masaaki Komatsu, et al.. (2005). The Crystal Structure of Human Atg4b, a Processing and De-conjugating Enzyme for Autophagosome-forming Modifiers. Journal of Molecular Biology. 355(4). 612–618. 72 indexed citations

19.

Unno, Masaki, Tsunehiro Mizushima, Y. Morimoto, et al.. (2002). The Structure of the Mammalian 20S Proteasome at 2.75 Å Resolution. Structure. 10(5). 609–618. 413 indexed citations

20.

Mitsuhashi, Satoshi, Tsunehiro Mizushima, Eiki Yamashita, et al.. (2000). X-ray Structure of β-Carbonic Anhydrase from the Red Alga,Porphyridium purpureum, Reveals a Novel Catalytic Site for CO2 Hydration. Journal of Biological Chemistry. 275(8). 5521–5526. 117 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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