Kunitada Shimotohno

27.3k total citations · 4 hit papers
355 papers, 21.8k citations indexed

About

Kunitada Shimotohno is a scholar working on Hepatology, Epidemiology and Immunology. According to data from OpenAlex, Kunitada Shimotohno has authored 355 papers receiving a total of 21.8k indexed citations (citations by other indexed papers that have themselves been cited), including 173 papers in Hepatology, 145 papers in Epidemiology and 110 papers in Immunology. Recurrent topics in Kunitada Shimotohno's work include Hepatitis C virus research (169 papers), Hepatitis B Virus Studies (122 papers) and T-cell and Retrovirus Studies (76 papers). Kunitada Shimotohno is often cited by papers focused on Hepatitis C virus research (169 papers), Hepatitis B Virus Studies (122 papers) and T-cell and Retrovirus Studies (76 papers). Kunitada Shimotohno collaborates with scholars based in Japan, United Kingdom and United States. Kunitada Shimotohno's co-authors include Makoto Hijikata, Nobuyuki Kato, Yuko Ootsuyama, Koichi Watashi, Howard M. Temin, Takayuki Hishiki, Yasunori Tanji, Shogo Ohkoshi, Tsuyoshi Akagi and Yoshiki Murakami and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Kunitada Shimotohno

352 papers receiving 20.8k citations

Hit Papers

Molecular cloning of the human hepatitis C virus genome f... 1990 2026 2002 2014 1990 2007 2005 1991 250 500 750 1000
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Molecular cloning of the human hepatitis C virus genome from Japanese patients with non-A, non-B hepatitis.
    1990 1.1k citations Makoto Hijikata, Kunitada Shimotohno et al. Proceedings of the National Academy of Sciences profile →
  2. The lipid droplet is an important organelle for hepatitis C virus production
    2007 995 citations Kimie Atsuzawa, Nobuteru Usuda et al. profile →
  3. Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues
    2005 946 citations Yoshiki Murakami, Hidenori Toyoda et al. profile →
  4. Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis.
    1991 539 citations Makoto Hijikata, Kunitada Shimotohno et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Kunitada Shimotohno Japan 74 10.4k 8.5k 7.8k 4.7k 2.2k 355 21.8k
Takaji Wakita Japan 78 15.4k 1.5× 13.6k 1.6× 5.4k 0.7× 2.7k 0.6× 547 0.3× 462 24.4k
Pierre Tiollais France 65 6.2k 0.6× 10.5k 1.2× 7.0k 0.9× 2.8k 0.6× 286 0.1× 202 18.2k
Jean Dubuisson France 71 10.4k 1.0× 8.5k 1.0× 3.1k 0.4× 1.4k 0.3× 479 0.2× 263 15.7k
Kui Li United States 53 4.0k 0.4× 4.3k 0.5× 2.9k 0.4× 4.7k 1.0× 463 0.2× 139 11.2k
Timothy M. Block United States 63 4.0k 0.4× 6.3k 0.7× 4.4k 0.6× 2.4k 0.5× 231 0.1× 232 12.6k
Michinori Kohara Japan 56 5.2k 0.5× 4.9k 0.6× 3.9k 0.5× 1.5k 0.3× 324 0.2× 263 11.3k
David J. Rowlands United Kingdom 58 1.6k 0.2× 2.4k 0.3× 5.1k 0.6× 912 0.2× 3.9k 1.8× 203 12.3k
Francis V. Chisari United States 117 25.5k 2.4× 29.8k 3.5× 7.8k 1.0× 14.8k 3.1× 266 0.1× 301 44.4k
Jane A. McKeating United Kingdom 73 12.2k 1.2× 11.2k 1.3× 3.6k 0.5× 3.9k 0.8× 216 0.1× 232 21.0k
Darius Moradpour Switzerland 61 10.4k 1.0× 7.4k 0.9× 3.6k 0.5× 3.0k 0.6× 219 0.1× 273 15.4k

Countries citing papers authored by Kunitada Shimotohno

Since Specialization
Citations

This map shows the geographic impact of Kunitada Shimotohno's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kunitada Shimotohno with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kunitada Shimotohno more than expected).

Fields of papers citing papers by Kunitada Shimotohno

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kunitada Shimotohno. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kunitada Shimotohno. The network helps show where Kunitada Shimotohno may publish in the future.

Co-authorship network of co-authors of Kunitada Shimotohno

This figure shows the co-authorship network connecting the top 25 collaborators of Kunitada Shimotohno. A scholar is included among the top collaborators of Kunitada Shimotohno based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kunitada Shimotohno. Kunitada Shimotohno is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Murayama, Asako, N. Yamada, Masaaki Toyama, et al.. (2025). A synonymous mutation in the preS2 region enhances production of infectious hepatitis B virus. Virology. 612. 110692–110692. 1 indexed citations
2.
Nishitsuji, Hironori, Kunitada Shimotohno, Shunpei Okada, et al.. (2025). MicroRNA-3145 as a potential therapeutic target for hepatitis B virus: inhibition of viral replication via downregulation of HBS and HBX. Frontiers in Microbiology. 15. 1499216–1499216.
3.
Murata, Takayuki, Satoko Iwahori, Yusuke Okuno, et al.. (2023). N6-methyladenosine Modification of Hepatitis B Virus RNA in the Coding Region of HBx. International Journal of Molecular Sciences. 24(3). 2265–2265. 7 indexed citations
4.
Morishita, Asahiro, Koji Fujita, Hisakazu Iwama, et al.. (2020). Role of microRNA-210-3p in hepatitis B virus-related hepatocellular carcinoma. American Journal of Physiology-Gastrointestinal and Liver Physiology. 318(3). G401–G409. 29 indexed citations
5.
Nakai, Masato, Tsukasa Seya, Misako Matsumoto, et al.. (2014). The J6JFH1 Strain of Hepatitis C Virus Infects Human B-Cells with Low Replication Efficacy. Viral Immunology. 27(6). 285–294. 8 indexed citations
6.
Aly, Hussein Hassan, Kunitada Shimotohno, Makoto Hijikata, & Tsukasa Seya. (2011). In vitro models for analysis of the hepatitis C virus life cycle. Microbiology and Immunology. 56(1). 1–9. 6 indexed citations
7.
Ohshima, Takayuki, et al.. (2010). HTLV‐1 basic leucine‐zipper factor, HBZ, interacts with MafB and suppresses transcription through a Maf recognition element. Journal of Cellular Biochemistry. 111(1). 187–194. 25 indexed citations
8.
Murakami, Yoshiki, Masami Tanaka, Hidenori Toyoda, et al.. (2010). Hepatic microRNA expression is associated with the response to interferon treatment of chronic hepatitis C. BMC Medical Genomics. 3(1). 48–48. 52 indexed citations
9.
Aly, Hussein Hassan, Yue Qi, Kimie Atsuzawa, et al.. (2009). Strain-dependent viral dynamics and virus-cell interactions in a novel in vitro system supporting the life cycle of blood-borne hepatitis C virus #. Hepatology. 50(3). 689–696. 15 indexed citations
10.
Arimoto, Kei‐ichiro, et al.. (2007). Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125. Proceedings of the National Academy of Sciences. 104(18). 7500–7505. 387 indexed citations
11.
Kodama, Yuzo, Makoto Hijikata, Ryoichiro Kageyama, Kunitada Shimotohno, & Tsutomu Chiba. (2004). The role of notch signaling in the development of intrahepatic bile ducts. Gastroenterology. 127(6). 1775–1786. 172 indexed citations
12.
Satoh, Shinya, Masami Hirota, Tohru Noguchi, et al.. (2000). Cleavage of Hepatitis C Virus Nonstructural Protein 5A by a Caspase-like Protease(s) in Mammalian Cells. Virology. 270(2). 476–487. 62 indexed citations
13.
Honda, Arata, Norio Hirota, Takako Sato, et al.. (1999). Hepatitis C virus structural proteins induce liver cell injury in transgenic mice. Journal of Medical Virology. 59(3). 281–289. 36 indexed citations
14.
Min, Byung Sun, Ki Hwan Bae, Young Ho Kim, et al.. (1999). Screening of Korean plants against human immunodeficiency virus type 1 protease. Phytotherapy Research. 13(8). 680–682. 34 indexed citations
15.
Min, Byung Sun, KiHwan Bae, Young Ho Kim, et al.. (1998). Inhibitory Activities of Korean Plants on HIV-1 Protease. Natural Product Sciences. 4(4). 241–244. 5 indexed citations
16.
17.
Tanaka, Yuetsu, Atsushi Yoshida, Hisatoshi Shida, et al.. (1992). An Antigenic Structure of the Trans -Activator Protein Encoded by Human T-Cell Leukemia Virus Type-I (HTLV-I), as Defined by a Panel of Monoclonal Antibodies. AIDS Research and Human Retroviruses. 8(2). 227–235. 12 indexed citations
18.
YAMASHITA, Kazuyo, Midori Maekawa, Kohnosuke Mitani, et al.. (1992). Evaluation of Enzyme Immunoassay Using a Recombinant Envelope Protein Expressed in Insect Cells for Serological Confirmation of HTLV-I Infection. AIDS Research and Human Retroviruses. 8(11). 1857–1861. 1 indexed citations
19.
Nyunoya, Hiroshi, Tsutomu Ogura, Masayoshi Kikuchi, et al.. (1990). Expression of HTLV-I Envelope Protein Fused to Hydrophobic Amino-Terminal Peptide of Baculovirus Polyhedrin in Insect Cells and Its Application for Serological Assays. AIDS Research and Human Retroviruses. 6(11). 1311–1321. 11 indexed citations
20.
Okamoto, Takashi, T. Matsuyama, Shigehisa Mori, et al.. (1989). Augmentation of Human Immunodeficiency Virus Type 1 Gene Expression by Tumor Necrosis Factor α. AIDS Research and Human Retroviruses. 5(2). 131–138. 92 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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