David Walker

3.2k citations

24 papers · 2.5k indexed · 2 hit papers · h-index 20

Impact in

Developmental Neuroscience top 2%
- Neurogenesis and neuroplasticity mechanisms
Neurology top 2%
- Neuroinflammation and Neurodegeneration Mechanisms

Papers in ⓘ

Neurology 4
- Neuroinflammation and Neurodegeneration Mechanisms 4
Cellular and Molecular Neuroscience 8
- Nuclear Receptors and Signaling 4
- Neuroscience and Neuropharmacology Research 3

Co-authors: Yadong Huang (10 shared papers)John M. Taylor (8 shared papers)Qin Xu (4 shared papers)Maureen E. Balestra (5 shared papers)Aubrey Bernardo (2 shared papers)Robert W. Mahley (2 shared papers)Seo Yeon Yoon (5 shared papers)Leslie M. Tong (4 shared papers)
Journals: Journal of Biological Chemistry (7 papers)Journal of Neuroscience (4 papers)PLoS ONE (2 papers)Journal of Economic Entomology (1 paper)Nature Medicine (1 paper)
Partner nations: United States Japan Netherlands

In The Last Decade

David Walker

24 papers receiving 2.4k citations

Hit Papers

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Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector 2018 · 284 citations

Peers

Countries citing papers authored by David Walker

Since Specialization

Citations

This map shows the geographic impact of David Walker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Walker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Walker more than expected).

Fields of papers citing papers by David Walker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Walker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Walker. The network helps show where David Walker may publish in the future.

Co-authors

The 25 scholars most cited alongside David Walker, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David Walker Line = papers co-authored together David Walker links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 24 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor Cell stem cell ·Karen Ring, Leslie M. Tong, Maureen E. Balestra, Robyn Javier, Yaisa Andrews‐Zwilling, Gang Li, David Walker, William R. Zhang, Anatol C. Kreitzer, Yadong Huang Hit paper breakdown →	2012	411
2	Profile and Regulation of Apolipoprotein E (ApoE) Expression in the CNS in Mice with Targeting of Green Fluorescent Protein Gene to the ApoE Locus Journal of Neuroscience ·Qin Xu, Aubrey Bernardo, David Walker, Tiffany Kanegawa, Robert W. Mahley, Yadong Huang	2006	382
3	Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector Nature Medicine ·Chengzhong Wang, Ramsey Najm, Qin Xu, Dah-Eun Jeong, David Walker, Maureen E. Balestra, Seo Yeon Yoon, Heidi Yuan, Gang Li, Zachary Miller, Bruce L. Miller, Mary J. Malloy, Yadong Huang Hit paper breakdown →	2018	284
4	The nucleotide and derived amino acid sequence of human apolipoprotein A-IV mRNA and the close linkage of its gene to the genes of apolipoproteins A-I and C-III. Journal of Biological Chemistry ·Nabil A. Elshourbagy, David Walker, Mark S. Boguski, Jeffrey I. Gordon, John M. Taylor	1986	135
5	Glycosylation of Human Apolipoprotein E Journal of Biological Chemistry ·M E Wernette-Hammond, SJ Lauer, Alberto Corsini, David Walker, John M. Taylor, S C Rall	1989	127
6	Reducing Human Apolipoprotein E Levels Attenuates Age-Dependent Aβ Accumulation in Mutant Human Amyloid Precursor Protein Transgenic Mice Journal of Neuroscience ·Nga Bien‐Ly, Anna K. Gillespie, David Walker, Seo Yeon Yoon, Yadong Huang	2012	124
7	Two copies of the human apolipoprotein C-I gene are linked closely to the apolipoprotein E gene. Journal of Biological Chemistry ·SJ Lauer, David Walker, Nabil A. Elshourbagy, Catherine A. Reardon, Beatriz Levy-Wilson, John M. Taylor	1988	117
8	Small Molecule Structure Correctors Abolish Detrimental Effects of Apolipoprotein E4 in Cultured Neurons Journal of Biological Chemistry ·Hung-Kai Chen, Zhaoping Liu, Anke Meyer‐Franke, Jens Brodbeck, R. Dennis Miranda, James G. McGuire, Michael A. Pleiss, Zhong-Sheng Ji, Maureen E. Balestra, David Walker, Qin Xu, Dah-eun Jeong, Madhu S. Budamagunta, John C. Voss, Stephen B. Freedman, Karl H. Weisgraber, Yadong Huang, Robert W. Mahley	2011	115
9	Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila Proceedings of the National Academy of Sciences ·Julien Muffat, David Walker, Seymour Benzer	2008	91
10	Intron-3 Retention/Splicing Controls Neuronal Expression of Apolipoprotein E in the CNS Journal of Neuroscience ·Qin Xu, David Walker, Aubrey Bernardo, Jens Brodbeck, Maureen E. Balestra, Yadong Huang	2008	90
11	Genetic Correction of Tauopathy Phenotypes in Neurons Derived from Human Induced Pluripotent Stem Cells Stem Cell Reports ·Helen Fong, Chengzhong Wang, Johanna Knöferle, David Walker, Maureen E. Balestra, Leslie M. Tong, Laura Leung, Karen Ring, William W. Seeley, Anna Karydas, M. Arpita Kshirsagar, Adam L. Boxer, Kenneth S. Kosik, Bruce L. Miller, Yadong Huang	2013	89
12	Apolipoprotein E4 Causes Age- and Sex-Dependent Impairments of Hilar GABAergic Interneurons and Learning and Memory Deficits in Mice PLoS ONE ·Laura Leung, Yaisa Andrews‐Zwilling, Seo Yeon Yoon, Sachi Jain, Karen Ring, Jessica Dai, Max Wang, Leslie M. Tong, David Walker, Yadong Huang	2012	87
13	Apolipoprotein E4 Produced in GABAergic Interneurons Causes Learning and Memory Deficits in Mice Journal of Neuroscience ·Johanna Knöferle, Seo Yeon Yoon, David Walker, Laura Leung, Anna K. Gillespie, Leslie M. Tong, Nga Bien‐Ly, Yadong Huang	2014	73
14	Identification and Characterization of a New Human Gene (APOC4) in the Apolipoprotein E, C-I, and C-II Gene Locus Genomics ·Charles M. Allan, David Walker, Jere P. Segrest, John M. Taylor	1995	67
15	Structure of the Hepatic Control Region of the Human Apolipoprotein E/C-I Gene Locus Journal of Biological Chemistry ·Qi Dang, David Walker, Stacy Taylor, Charles M. Allan, Peter Chin, Jianglin Fan, John M. Taylor	1995	62
16	Evolutionary Duplication of a Hepatic Control Region in the Human Apolipoprotein E Gene Locus Journal of Biological Chemistry ·Charles M. Allan, David Walker, John M. Taylor	1995	56
17	Characterization of a human apolipoprotein E gene enhancer element and its associated protein factors. Journal of Biological Chemistry ·David J. Chang, Young‐Ki Paik, Trond P. Leren, David Walker, G.J. Howlett, John M. Taylor	1990	47
18	Effect of alteration of maternal plasma progesterone concentrations on fetal behavioural state during late gestation Journal of Endocrinology ·Marcus Nicol, Jonathan J. Hirst, David Walker, G D Thorburn	1997	39
19	Arf4 Determines Dentate Gyrus-Mediated Pattern Separation by Regulating Dendritic Spine Development PLoS ONE ·Sachi Jain, Seo Yeon Yoon, Lei Zhu, Jens Brodbeck, Jessica Dai, David Walker, Yadong Huang	2012	33
20	Expression of the Apolipoprotein E Gene in the Skin is Controlled by a Unique Downstream Enhancer Journal of Investigative Dermatology ·Sharon Grehan, Charles M. Allan, Elizabeth Tse, David Walker, John M. Taylor	2001	21

About David Walker

David Walker is a scholar working on Neurology, Cellular and Molecular Neuroscience, Physiology, Developmental Neuroscience and Molecular Biology, having authored 24 papers that have together received 2.5k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (8 papers), Peroxisome Proliferator-Activated Receptors (5 papers), Nuclear Receptors and Signaling (4 papers), Neuroinflammation and Neurodegeneration Mechanisms (4 papers), Retinoids in leukemia and cellular processes (3 papers), Cholinesterase and Neurodegenerative Diseases (3 papers), Neuroscience and Neuropharmacology Research (3 papers) and Machine Learning in Bioinformatics (2 papers). The work is most often cited by research in Developmental Neuroscience (239 citations), Neurology (308 citations), Physiology (940 citations), Cellular and Molecular Neuroscience (564 citations) and Aging (50 citations). David Walker has collaborated with scholars based in United States, Japan and Netherlands. Frequent co-authors include Yadong Huang, John M. Taylor, Qin Xu, Maureen E. Balestra, Aubrey Bernardo, Robert W. Mahley, Seo Yeon Yoon, Leslie M. Tong, Gang Li and Karen Ring. Their work appears in journals such as Journal of Biological Chemistry, Journal of Neuroscience, PLoS ONE, Journal of Economic Entomology and Nature Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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