Herbert E. Klei

3.9k total citations · 1 hit paper
54 papers, 1.8k citations indexed

About

Herbert E. Klei is a scholar working on Molecular Biology, Materials Chemistry and Biomedical Engineering. According to data from OpenAlex, Herbert E. Klei has authored 54 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Molecular Biology, 15 papers in Materials Chemistry and 10 papers in Biomedical Engineering. Recurrent topics in Herbert E. Klei's work include Enzyme Structure and Function (9 papers), Biochemical and Molecular Research (6 papers) and Microbial Metabolic Engineering and Bioproduction (6 papers). Herbert E. Klei is often cited by papers focused on Enzyme Structure and Function (9 papers), Biochemical and Molecular Research (6 papers) and Microbial Metabolic Engineering and Bioproduction (6 papers). Herbert E. Klei collaborates with scholars based in United States, Germany and Italy. Herbert E. Klei's co-authors include D. W. Sundstrom, Barbara A. Weir, Kevin Kish, Dianlin Xie, Yaqun Zhang, Susan E. Kiefer, Michael Wittekind, Louis J. Lombardo, John A. Newitt and John S. Tokarski and has published in prestigious journals such as Blood, PLoS ONE and Water Research.

In The Last Decade

Herbert E. Klei

54 papers receiving 1.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain Elucidates Its Inhibitory Activity against Imatinib-Resistant ABL Mutants

2006 522 citations John S. Tokarski, John A. Newitt et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Herbert E. Klei United States	21	687	425	294	262	257	54	1.8k
Zheng Zhao China	27	1.2k 1.8×	167 0.4×	165 0.6×	199 0.8×	554 2.2×	70	2.7k
André M. N. Silva Portugal	20	549 0.8×	258 0.6×	191 0.6×	188 0.7×	133 0.5×	60	1.5k
Breno Pannia Espósito Brazil	20	375 0.5×	568 1.3×	465 1.6×	184 0.7×	235 0.9×	71	1.7k
Peter‐Leon Hagedoorn Netherlands	33	1.5k 2.1×	349 0.8×	59 0.2×	494 1.9×	245 1.0×	127	3.2k
Yǔji Inada Japan	33	1.9k 2.7×	154 0.4×	64 0.2×	397 1.5×	371 1.4×	167	3.3k
Fumin Xue China	21	518 0.8×	252 0.6×	268 0.9×	653 2.5×	220 0.9×	81	2.1k
Paul S. Dobbin United Kingdom	21	475 0.7×	159 0.4×	178 0.6×	191 0.7×	155 0.6×	41	1.6k
Donald H. Atha United States	23	1.3k 2.0×	316 0.7×	97 0.3×	522 2.0×	242 0.9×	62	2.8k
João M.L. Dias Portugal	22	888 1.3×	105 0.2×	63 0.2×	189 0.7×	34 0.1×	56	1.9k
Laura Passerini Italy	26	383 0.6×	109 0.3×	58 0.2×	50 0.2×	93 0.4×	56	2.6k

Countries citing papers authored by Herbert E. Klei

Since Specialization

Citations

This map shows the geographic impact of Herbert E. Klei's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Herbert E. Klei with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Herbert E. Klei more than expected).

Fields of papers citing papers by Herbert E. Klei

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Herbert E. Klei. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Herbert E. Klei. The network helps show where Herbert E. Klei may publish in the future.

Co-authorship network of co-authors of Herbert E. Klei

This figure shows the co-authorship network connecting the top 25 collaborators of Herbert E. Klei. A scholar is included among the top collaborators of Herbert E. Klei based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Herbert E. Klei. Herbert E. Klei is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Hiebert, Sheldon, Jacques Friborg, Fei Yu, et al.. (2017). The discovery and optimization of naphthalene-linked P2-P4 Macrocycles as inhibitors of HCV NS3 protease. Bioorganic & Medicinal Chemistry Letters. 28(1). 43–48. 8 indexed citations

Chen, Jie, Qian Zhao, Li‐Qiang Sun, et al.. (2016). Structure-activity relationships of 4-hydroxy-4-biaryl-proline acylsulfonamide tripeptides: A series of potent NS3 protease inhibitors for the treatment of hepatitis C virus. Bioorganic & Medicinal Chemistry Letters. 27(3). 590–596. 5 indexed citations

Hassan, Md. Imtaiyaz, et al.. (2013). High Resolution Crystal Structure of Human β-Glucuronidase Reveals Structural Basis of Lysosome Targeting. PLoS ONE. 8(11). e79687–e79687. 46 indexed citations

Klei, Herbert E., Nigel W. Moriarty, Nathaniel Echols, et al.. (2013). Ligand placement based on prior structures: the guided ligand-replacement method. Acta Crystallographica Section D Biological Crystallography. 70(1). 134–143. 10 indexed citations

Echols, Nathaniel, Nigel W. Moriarty, Herbert E. Klei, et al.. (2013). Automating crystallographic structure solution and refinement of protein–ligand complexes. Acta Crystallographica Section D Biological Crystallography. 70(1). 144–154. 40 indexed citations

Wang, Wei, Pratik Devasthale, Aiying Wang, et al.. (2011). 7-Oxopyrrolopyridine-derived DPP4 inhibitors—mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site. Bioorganic & Medicinal Chemistry Letters. 21(22). 6646–6651. 15 indexed citations

Shi, Yan, Jing Zhang, Mengxiao Shi, et al.. (2009). Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors. Bioorganic & Medicinal Chemistry Letters. 19(15). 4034–4041. 13 indexed citations

Metzler, William J., Joseph Yanchunas, Carolyn A. Weigelt, et al.. (2008). Involvement of DPP‐IV catalytic residues in enzyme–saxagliptin complex formation. Protein Science. 17(2). 240–250. 103 indexed citations

Terwilliger, Thomas C., Herbert E. Klei, Paul D. Adams, Nigel W. Moriarty, & Judith D. Cohn. (2006). Automated ligand fitting by core-fragment fitting and extension into density. Acta Crystallographica Section D Biological Crystallography. 62(8). 915–922. 93 indexed citations

10.

Tokarski, John S., John A. Newitt, Francis Y. Lee, et al.. (2004). The Crystal Structure of Abl Kinase with BMS-354825, a Dual SRC/ABL Kinase Inhibitor.. Blood. 104(11). 553–553. 21 indexed citations

11.

McDonough, M.A., et al.. (1999). Crystal structure of penicillin G acylase from the bro1 mutant strain of providencia rettgeri. Protein Science. 8(10). 1971–1981. 43 indexed citations

12.

Gawlak, Susan L., Michael Neubauer, Herbert E. Klei, et al.. (1997). Molecular, Biological, and Preliminary Structural Analysis of Recombinant Bryodin 1, a Ribosome-Inactivating Protein from the PlantBryonia dioica. Biochemistry. 36(11). 3095–3103. 19 indexed citations

13.

Klei, Herbert E., Judith A. Kelly, & Gaston O. Daumy. (1995). Purification and preliminary crystallographic studies of penicillin G acylase from Providencia rettgeri. Protein Science. 4(3). 433–441. 17 indexed citations

14.

Sundstrom, D. W., et al.. (1992). Destruction of Pollutants and Microorganisms in Water by UV Light and Hydrogen Peroxide. Water Quality Research Journal. 27(1). 57–68. 12 indexed citations

15.

Bunning, Timothy J., Carl Lawton, Herbert E. Klei, & D. W. Sundstrom. (1991). Physical property improvements of a pellicular biocatalyst. Bioprocess Engineering. 7(1-2). 71–75. 5 indexed citations

16.

Flanagan, William P., Herbert E. Klei, D. W. Sundstrom, & Carl Lawton. (1990). Optimization of a pellicular biocatalyst for penicillin G production by Penicillium chrysogenum. Biotechnology and Bioengineering. 36(6). 608–616. 15 indexed citations

17.

Weir, Barbara A., D. W. Sundstrom, & Herbert E. Klei. (1987). Destruction of Benzene by Ultraviolet Light-Catalyzed Oxidation with Hydrogen Peroxide. Hazardous Waste and Hazardous Materials. 4(2). 165–176. 31 indexed citations

18.

Sundstrom, D. W., et al.. (1986). Destruction of Halogenated Aliphatics by Ultraviolet Catalyzed Oxidation with Hydrogen Peroxide. Hazardous Waste and Hazardous Materials. 3(1). 101–110. 71 indexed citations

19.

Sundstrom, D. W., et al.. (1983). Response of composition in biological reactors to changes in inlet concentration. Biotechnology and Bioengineering. 25(3). 857–861. 3 indexed citations

20.

Sundstrom, D. W. & Herbert E. Klei. (1982). Uses of by-product lignins from alcohol fuel processes. 9 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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