Matthew Mangan

6.7k total citations · 2 hit papers
26 papers, 3.9k citations indexed

About

Matthew Mangan is a scholar working on Immunology, Molecular Biology and Cancer Research. According to data from OpenAlex, Matthew Mangan has authored 26 papers receiving a total of 3.9k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Immunology, 16 papers in Molecular Biology and 7 papers in Cancer Research. Recurrent topics in Matthew Mangan's work include Inflammasome and immune disorders (11 papers), Immune Response and Inflammation (6 papers) and Protease and Inhibitor Mechanisms (6 papers). Matthew Mangan is often cited by papers focused on Inflammasome and immune disorders (11 papers), Immune Response and Inflammation (6 papers) and Protease and Inhibitor Mechanisms (6 papers). Matthew Mangan collaborates with scholars based in Germany, United States and Australia. Matthew Mangan's co-authors include Eicke Latz, H. Martin Seidel, Gary D. Glick, William Roush, Edward J. Olhava, John M. Clements, Graham Wells, Alan H. Davidson, Alan H. Drummond and William C. Thomas and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Immunity.

In The Last Decade

Matthew Mangan

26 papers receiving 3.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Targeting the NLRP3 inflammasome in inflammatory diseases

2018 1.5k citations Matthew Mangan, Edward J. Olhava et al. Nature Reviews Drug Discovery profile →
Processing of tumour necrosis factor-α precursor by metalloproteinases

1994 1.0k citations A. J. H. Gearing, Paul Beckett et al. Nature profile →

Peers

Countries citing papers authored by Matthew Mangan

Since Specialization

Citations

This map shows the geographic impact of Matthew Mangan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Matthew Mangan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Matthew Mangan more than expected).

Fields of papers citing papers by Matthew Mangan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Matthew Mangan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Matthew Mangan. The network helps show where Matthew Mangan may publish in the future.

Co-authorship network of co-authors of Matthew Mangan

This figure shows the co-authorship network connecting the top 25 collaborators of Matthew Mangan. A scholar is included among the top collaborators of Matthew Mangan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Matthew Mangan. Matthew Mangan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Butyrate and propionate are microbial danger signals that activate the NLRP3 inflammasome in human macrophages upon TLR stimulation 2024 ·Cell Reports ·Wei Wang, (unknown), (unknown), (unknown), (unknown), Kshiti Phulphagar, (unknown), (unknown), (unknown), Theresa Wagner, Harald Färber, (unknown), Rainer Stahl, Fraser Duthie, Susanne V. Schmidt, Rebecca C. Coll, Felix Meissner, Sergi Cuartero, Eicke Latz, Matthew Mangan	35
2	Monitoring of Inflammasome Activation of Macrophages and Microglia In Vitro, Part 2: Assessing Inflammasome Activation 2023 ·Methods in molecular biology ·Marta Lovotti, Matthew Mangan, Róisín M. McManus, Kateryna Shkarina, (unknown), Eicke Latz	1
3	Cutting Edge: STING Induces ACLY Activation and Metabolic Adaptations in Human Macrophages through TBK1 2023 ·The Journal of Immunology ·(unknown), Matthew Mangan, Hye‐Eun Lee, (unknown), Antonia Henne, Romina Kaiser, (unknown), (unknown), Zeinab Abdullah, Karsten Hiller, Eicke Latz, Mario Lauterbach	3
4	Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever 2022 ·PLoS Biology ·Matthew Mangan, (unknown), Karoline Krause, (unknown), Anne Pankow, Thomas S. Ebert, Dieter Jahn, Karsten Hiller, Veit Hornung, Marcus Maurer, Florian I. Schmidt, Ralf Gerhard, Eicke Latz	9
5	How location and cellular signaling combine to activate the NLRP3 inflammasome 2022 ·Cellular and Molecular Immunology ·(unknown), (unknown), Marta Lovotti, Matthew Mangan, Róisín M. McManus, Eicke Latz	142
6	1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation 2020 ·Autophagy ·Mario Lauterbach, (unknown), Matthew Mangan, Anke Penno, Christoph Thiele, Eicke Latz, Lars Kuerschner	34
7	Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase 2019 ·Immunity ·Mario Lauterbach, (unknown), (unknown), Matthew Mangan, Carl‐Christian Kolbe, Timo Hess, Maximilian Rothe, Romina Kaiser, Florian Hoß, Jan Gehlen, Gudrun Engels, (unknown), Susanne V. Schmidt, Anette Christ, Axel Imhof, Karsten Hiller, Eicke Latz	297
8	Erratum: Targeting the NLRP3 inflammasome in inflammatory diseases 2018 ·Nature Reviews Drug Discovery ·Matthew Mangan, Edward J. Olhava, William Roush, H. Martin Seidel, Gary D. Glick, Eicke Latz	349
9	Targeting the NLRP3 inflammasome in inflammatory diseases breakdown → 2018 ·Nature Reviews Drug Discovery ·Matthew Mangan, Edward J. Olhava, William Roush, H. Martin Seidel, Gary D. Glick, Eicke Latz	1460
10	A pro‐survival role for the intracellular granzyme B inhibitor Serpinb9 in natural killer cells during poxvirus infection 2017 ·Immunology and Cell Biology ·Matthew Mangan, (unknown), (unknown), Catherina H. Bird, Aulikki Koskinen, Alexandra Rizzitelli, Monica D. Prakash, Katrina L. Scarff, Arno Müllbacher, Matthias Regner, Phillip I. Bird	20
11	Serpinb9 is a marker of antigen cross-presenting dendritic cells 2016 ·Molecular Immunology ·Matthew Mangan, Javier Vega‐Ramos, Lars T. Joeckel, Andrew J. Mitchell, Alexandra Rizzitelli, Ben Roediger, Dion Kaiserman, (unknown), Jóse A. Villadangos, Phillip I. Bird	19
12	Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation [version 1; referees: 2 approved] 2016 ·Tomasz Próchnicki, Matthew Mangan, Eicke Latz	1
13	Crystal Formation in Inflammation 2016 ·Annual Review of Immunology ·Bernardo S. Franklin, Matthew Mangan, Eicke Latz	105
14	A Novel Serpin Regulatory Mechanism 2015 ·Journal of Biological Chemistry ·Matthew Mangan, Catherina H. Bird, Dion Kaiserman, (unknown), (unknown), David L. Steer, Philip E. Thompson, Phillip I. Bird	16
15	The granzyme B-Serpinb9 axis controls the fate of lymphocytes after lysosomal stress 2014 ·Cell Death and Differentiation ·Catherina H. Bird, Melinda E. Christensen, Matthew Mangan, Monica D. Prakash, Karin Sedelies, Mark J. Smyth, Ian S. Harper, Nigel J. Waterhouse, Phillip I. Bird	33
16	The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins 2013 ·Acta Crystallographica Section D Biological Crystallography ·M. Obayed Ullah, Thomas Ve, Matthew Mangan, Mohammed Alaidarous, Matthew J. Sweet, Ashley Mansell, Boštjan Kobe	14
17	The role of serpins in vertebrate immunity 2008 ·Tissue Antigens ·Matthew Mangan, Dion Kaiserman, Phillip I. Bird	67
18	The synthesis of novel matrix metalloproteinase inhibitors employing the Ireland-Claisen rearrangement 1998 ·Bioorganic & Medicinal Chemistry Letters ·Lisa M. Pratt, R. Paul Beckett, (unknown), Dominic J. Corkill, Judy Cossins, (unknown), Stephen J. Davies, Alan H. Davidson, Alan H. Drummond, (unknown), H Lewis, Matthew Mangan, (unknown), Karen I. Miller, (unknown), (unknown), (unknown), Richard S. Todd, Mark Whittaker	18
19	Quantitation of matrix metalloproteinases in cultured rat astrocytes using the polymerase chain reaction with a multi‐competitor cDNA standard 1996 ·Glia ·Graham Wells, Graham Catlin, Judy Cossins, Matthew Mangan, George A. Ward, Karen Miller, John M. Clements	7
20	Processing of tumour necrosis factor-α precursor by metalloproteinases breakdown → 1994 ·Nature ·A. J. H. Gearing, Paul Beckett, Marika Christodoulou, Melvin Churchill, John M. Clements, Alan H. Davidson, Alan H. Drummond, W A Galloway, Robert J.C. Gilbert, Jacob Gordon, (unknown), Matthew Mangan, Karl N. Miller, (unknown), Katherine A. Owen, Sachin Patel, William C. Thomas, Graham Wells, L M Wood, Karen L. Woolley	1021

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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