Tiernan T. O’Malley

2.3k citations

25 papers · 1.7k indexed · h-index 18

Physiology top 2%
- Alzheimer's disease research and treatments 21
Neurology top 2%
- Neuroinflammation and Neurodegeneration Mechanisms 3
Biological Psychiatry top 5%
Cellular and Molecular Neuroscience top 5%
- Neuroscience and Neuropharmacology Research 6
Pharmacology top 5%
- Cholinesterase and Neurodegenerative Diseases 5
Computational Theory and Mathematics
- Computational Drug Discovery Methods 8
Molecular Biology
- Lipid Membrane Structure and Behavior 3
- Glycosylation and Glycoproteins Research 2
Radiology, Nuclear Medicine and Imaging
- Monoclonal and Polyclonal Antibodies Research 3

Co-authors: Dominic M. Walsh Dennis J. Selkoe Ming Jin Ting Yang Soyon Hong Zemin Wang Shaomin Li Michael J. Rowan
Cited by: Physiology Neurology Biological Psychiatry
Journals: Alzheimer s & Dementia (3 papers)Nature Communications (3 papers)Journal of Neuroscience (2 papers)
Partner nations: United States Ireland Sweden

In The Last Decade

Tiernan T. O’Malley

25 papers receiving 1.7k citations

Peers

Countries citing papers authored by Tiernan T. O’Malley

Since Specialization

Citations

This map shows the geographic impact of Tiernan T. O’Malley's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tiernan T. O’Malley with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tiernan T. O’Malley more than expected).

Fields of papers citing papers by Tiernan T. O’Malley

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tiernan T. O’Malley. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tiernan T. O’Malley. The network helps show where Tiernan T. O’Malley may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Tiernan T. O’Malley, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tiernan T. O’Malley Line = papers co-authored together Tiernan T. O’Malley links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Tau and Amyloid β Protein in Patient-Derived Aqueous Brain Extracts Act Concomitantly to Disrupt Long-Term Potentiationin Vivo Journal of Neuroscience ·Tomáš Ondrejčák,Igor Klyubin,Neng‐Wei Hu,Tiernan T. O’Malley,Grant T. Corbett,Na Li,Michael S. Perkinton,Andy Billinton,Jack Prenderville,Dominic M. Walsh,Michael J. Rowan	2023	8
2	Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies Nature Structural & Molecular Biology ·Sara Linse,Tom Scheidt,Katja Bernfur,Michele Vendruscolo,Christopher M. Dobson,Samuel I. A. Cohen,Marie Mangan,Martin Lundqvist,Fang Qian,Tiernan T. O’Malley,Thierry Bussière,Paul H. Weinreb,Catherine K. Xu,Georg Meisl,Sean R. A. Devenish,Tuomas P. J. Knowles,Oskar Hansson	2020	154
3	Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer’s brain Brain ·Gunnar Brinkmalm,Wei Hong,Zemin Wang,Wen Liu,Tiernan T. O’Malley,Xin Sun,Matthew P. Frosch,Dennis J. Selkoe,Erik Portelius,Henrik Zetterberg,Kaj Blennow,Dominic M. Walsh	2019	75
4	Diffusible, highly bioactive oligomers represent a critical minority of soluble Aβ in Alzheimer’s disease brain Acta Neuropathologica ·Wei Hong,Zemin Wang,Wen Liu,Tiernan T. O’Malley,Ming Jin,Michael Willem,Christian Haass,Matthew P. Frosch,Dominic M. Walsh	2018	105
5	An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease Nature Communications ·Ming Jin,Brian O’Nuallain,Wei Hong,Justin D. Boyd,Valentina N. Lagomarsino,Tiernan T. O’Malley,Wen Liu,Charles Vanderburg,Matthew P. Frosch,Tracy L. Young‐Pearse,Dennis J. Selkoe,Dominic M. Walsh	2018	48
6	Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer’s Disease Disrupt Synaptic Plasticity Cell Reports ·Neng‐Wei Hu,Grant T. Corbett,Steven Moore,Igor Klyubin,Tiernan T. O’Malley,Dominic M. Walsh,Frederick J. Livesey,Michael J. Rowan	2018	59
7	Production and Use of Recombinant Aβ for Aggregation Studies Methods in molecular biology ·Tiernan T. O’Malley,Sara Linse,Dominic M. Walsh	2018	8
8	Lessons from the Study of Covalent Dimers of the Alzheimer’s Disease-Associate Amyloid β-Protein Tiernan T. O’Malley,Dominic M. Walsh	2018	2
9	The Aggregation Paths and Products of Aβ42 Dimers Are Distinct from Those of the Aβ42 Monomer Biochemistry ·Tiernan T. O’Malley,Claudia Siedel,Sara Linse,Dominic M. Walsh	2016	22
10	C-Terminally Truncated Forms of Tau, But Not Full-Length Tau or Its C-Terminal Fragments, Are Released from Neurons Independently of Cell Death Journal of Neuroscience ·Daniel Kanmert,Adam Cantlon,Christina Muratore,Ming Jin,Tiernan T. O’Malley,Gloria Lee,Tracy L. Young‐Pearse,Dennis J. Selkoe,Dominic M. Walsh	2015	131
11	Soluble Aβ oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance Neurobiology of Disease ·Ming Lei,Huixin Xu,W. Trautmann,Zemin Wang,Tiernan T. O’Malley,Jean‐Charles Sébileau,Dominic M. Walsh,Pingyi Xu,Dennis J. Selkoe,Shaomin Li	2015	127
12	IgG Conformer's Binding to Amyloidogenic Aggregates PLoS ONE ·Yu. F. Druzhinina,Alfred T. Welzel,Angela D. Williams,服部正裕,幸弘半田,Tiernan T. O’Malley,Alan Solomon,Dominic M. Walsh,Brian O’Nuallain	2015	5
13	Targeted Magnetic Nanoparticles for Remote Magnetothermal Disruption of Amyloid‐β Aggregates Advanced Healthcare Materials ·Colleen N. Loynachan,Gabriela Romero,Michael G. Christiansen,Ritchie Chen,Małgorzata Janiczek,Tiernan T. O’Malley,Ulrich P. Froriep,Dominic M. Walsh,Polina Anikeeva	2015	31
14	The aqueous phase of Alzheimer's disease brain contains assemblies built from ∼4 and ∼7 kDa Aβ species Alzheimer s & Dementia ·Jessica M. Mc Donald,Tiernan T. O’Malley,Wen Liu,Alexandra J. Mably,Gunnar Brinkmalm,Erik Portelius,Socorro E Zavarce,Matthew P. Frosch,Dominic M. Walsh	2015	49
15	APP Homodimers Transduce an Amyloid-β-Mediated Increase in Release Probability at Excitatory Synapses Cell Reports ·Hilla Fogel,Samuel Frère,Oshik Segev,Shashank Bharill,Ilana Shapira,Neta Gazit,Tiernan T. O’Malley,Edden Slomowitz,Yevgeny Berdichevsky,Dominic M. Walsh,Ehud Y. Isacoff,Joel A. Hirsch,Inna Slutsky	2014	101
16	mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo Nature Communications ·Neng‐Wei Hu,Andrew J. Nicoll,Jean‐Charles Sébileau,Alexandra J. Mably,Tiernan T. O’Malley,Silvia A. Purro,Cassandra Terry,John Collinge,Dominic M. Walsh,Michael J. Rowan	2014	143
17	Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes Neuron ·Soyon Hong,Beth L. Ostaszewski,Ting Yang,Tiernan T. O’Malley,Ming Jin,Katsuhiko Yanagisawa,Shaomin Li,Tim Bartels,Dennis J. Selkoe	2014	167
18	Aβ dimers differ from monomers in structural propensity, aggregation paths and population of synaptotoxic assemblies Biochemical Journal ·Tiernan T. O’Malley,Nur Alia Oktaviani,Dainan Zhang,Aleksey Lomakin,Brian O’Nuallain,Sara Linse,George B. Benedek,Michael J. Rowan,Frans A. A. Mulder,Dominic M. Walsh	2014	60
19	Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity Nature Communications ·Andrew J. Nicoll,Silvia Panico,Darragh B. Freir,Daniel Wright,Cassandra Terry,Emmanuel Risse,Caroline E. Herron,Tiernan T. O’Malley,Jonathan D. F. Wadsworth,Mark A. Farrow,Dominic M. Walsh,Helen R. Saibil,John Collinge	2013	104
20	New ELISAs with high specificity for soluble oligomers of amyloid β‐protein detect natural Aβ oligomers in human brain but not CSF Alzheimer s & Dementia ·Ting Yang,Soyon Hong,Tiernan T. O’Malley,Reisa A. Sperling,Dominic M. Walsh,Dennis J. Selkoe	2013	105

About Tiernan T. O’Malley

Tiernan T. O’Malley is a scholar working on Physiology, Computational Theory and Mathematics and Neurology, having authored 25 papers that have together received 1.7k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (21 papers), Computational Drug Discovery Methods (8 papers), Neuroscience and Neuropharmacology Research (6 papers), Cholinesterase and Neurodegenerative Diseases (5 papers), Lipid Membrane Structure and Behavior (3 papers), Monoclonal and Polyclonal Antibodies Research (3 papers), Neuroinflammation and Neurodegeneration Mechanisms (3 papers) and Glycosylation and Glycoproteins Research (2 papers). The work is most often cited by research in Physiology (1.3k citations), Neurology (371 citations) and Biological Psychiatry (92 citations). Tiernan T. O’Malley has collaborated with scholars based in United States, Ireland and Sweden. Frequent co-authors include Dominic M. Walsh, Dennis J. Selkoe, Ming Jin, Ting Yang, Soyon Hong, Zemin Wang, Shaomin Li, Michael J. Rowan, Wen Liu and Matthew P. Frosch. Their work appears in journals such as Alzheimer s & Dementia, Nature Communications, Journal of Neuroscience, Cell Reports and Advanced Healthcare Materials.

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