Edgar Jacoby

5.3k citations

88 papers · 4.0k indexed · h-index 31

Impact in

Computational Theory and Mathematics top 0.1%
- Computational Drug Discovery Methods
Molecular Biology top 2%
- Protein Structure and Dynamics
- Receptor Mechanisms and Signaling
- Chemical Synthesis and Analysis
- Bioinformatics and Genomic Networks

Papers in ⓘ

Computational Theory and Mathematics 47
- Computational Drug Discovery Methods 47
Molecular Biology 66
- Chemical Synthesis and Analysis 17
- Protein Structure and Dynamics 14
- Receptor Mechanisms and Signaling 14
- Bioinformatics and Genomic Networks 12
- Genetics, Bioinformatics, and Biomedical Research 6

Co-authors: Ansgar Schuffenhauer (16 shared papers)Pierre Acklin (12 shared papers)Markus Bredel (1 shared paper)Khalil Azzaoui (10 shared papers)Jérôme Hert (4 shared papers)Peter Willett (4 shared papers)David J. Wilton (4 shared papers)Michael Engels (5 shared papers)
Journals: Journal of Chemical Information and Modeling (7 papers)Journal of Medicinal Chemistry (5 papers)Bioorganic & Medicinal Chemistry Letters (4 papers)Protein Engineering Design and Selection (4 papers)ACS Medicinal Chemistry Letters (3 papers)
Partner nations: Switzerland Belgium United States

In The Last Decade

Edgar Jacoby

87 papers receiving 3.8k citations

Peers

Countries citing papers authored by Edgar Jacoby

Since Specialization

Citations

This map shows the geographic impact of Edgar Jacoby's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edgar Jacoby with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edgar Jacoby more than expected).

Fields of papers citing papers by Edgar Jacoby

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edgar Jacoby. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edgar Jacoby. The network helps show where Edgar Jacoby may publish in the future.

Co-authors

The 25 scholars most cited alongside Edgar Jacoby, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Edgar Jacoby Line = papers co-authored together Edgar Jacoby links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 88 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Targeted Molecular Dynamics Simulation of Conformational Change-Application to the T ↔ R Transition in Insulin Molecular Simulation ·J. Schlitter, Michael Engels, Péter Krüger, Edgar Jacoby, Axel Wollmer	1993	353
2	The 7 TM G‐Protein‐Coupled Receptor Target Family ChemMedChem ·Edgar Jacoby, Rochdi Bouhelal, Marc Gerspacher, Klaus Seuwen	2006	275
3	Chemogenomics: an emerging strategy for rapid target and drug discovery Nature Reviews Genetics ·Markus Bredel, Edgar Jacoby	2004	253
4	Comparison of Fingerprint-Based Methods for Virtual Screening Using Multiple Bioactive Reference Structures Journal of Chemical Information and Computer Sciences ·Jérôme Hert, Peter Willett, David J. Wilton, Pierre Acklin, Khalil Azzaoui, Edgar Jacoby, Ansgar Schuffenhauer	2004	239
5	Comparison of topological descriptors for similarity-based virtual screening using multiple bioactive reference structures Organic & Biomolecular Chemistry ·Jérôme Hert, Peter Willett, David J. Wilton, Pierre Acklin, Khalil Azzaoui, Edgar Jacoby, Ansgar Schuffenhauer	2004	204
6	Similarity Metrics for Ligands Reflecting the Similarity of the Target Proteins Journal of Chemical Information and Computer Sciences ·Ansgar Schuffenhauer, Philipp Floersheim, Pierre Acklin, Edgar Jacoby	2002	193
7	A Small-Molecule Dengue Virus Entry Inhibitor Antimicrobial Agents and Chemotherapy ·Qingyin Wang, Sejal Patel, Eric Vangrevelinghe, Hao Xu, Ranga Rao, Deana Jaber, Wouter Schul, Feng Gu, Olivier Heudi, Ngai Ling, Mee Kian Poh, Wai Yee Phong, Thomas H. Keller, Edgar Jacoby, Subhash G. Vasudevan	2009	178
8	New Methods for Ligand-Based Virtual Screening: Use of Data Fusion and Machine Learning to Enhance the Effectiveness of Similarity Searching Journal of Chemical Information and Modeling ·Jérôme Hert, Peter Willett, David J. Wilton, Pierre Acklin, Khalil Azzaoui, Edgar Jacoby, Ansgar Schuffenhauer	2006	167
9	Library Design for Fragment Based Screening Current Topics in Medicinal Chemistry ·Ansgar Schuffenhauer, Simon Ruedisser, Andreas L. Marzinzik, Wolfgang Jahnke, Paul M. Selzer, Edgar Jacoby	2005	135
10	Modeling Promiscuity Based on in vitro Safety Pharmacology Profiling Data ChemMedChem ·Khalil Azzaoui, Jacques Hamon, Bernard Faller, Steven Whitebread, Edgar Jacoby, Andreas Bender, Jeremy L. Jenkins, László Urbán	2007	127
11	On Scaffolds and Hopping in Medicinal Chemistry Mini-Reviews in Medicinal Chemistry ·Nathan Brown, Edgar Jacoby	2006	122
12	Molecular Lipophilicity in Protein Modeling and Drug Design Current Medicinal Chemistry ·Roman G. Efremov, Anton O. Chugunov, Timothy V. Pyrkov, John P. Priestle, Alexander S. Arseniev, Edgar Jacoby	2007	121
13	A Collection of Robust Organic Synthesis Reactions for In Silico Molecule Design Journal of Chemical Information and Modeling ·Markus Hartenfeller, Martin Eberle, Peter Meier, Cristina Nieto‐Oberhuber, Karl‐Heinz Altmann, Gisbert Schneider, Edgar Jacoby, Steffen Renner	2011	91
14	Relationships between Molecular Complexity, Biological Activity, and Structural Diversity Journal of Chemical Information and Modeling ·Ansgar Schuffenhauer, Nathan Brown, Paul M. Selzer, Peter Ertl, Edgar Jacoby	2005	71
15	An Ontology for Pharmaceutical Ligands and Its Application for in Silico Screening and Library Design Journal of Chemical Information and Computer Sciences ·Ansgar Schuffenhauer, J. Zimmermann, Ruedi Stoop, Jan‐Jan van der Vyver, Steffano Lecchini, Edgar Jacoby	2002	70
16	Enhancing the Effectiveness of Similarity-Based Virtual Screening Using Nearest-Neighbor Information Journal of Medicinal Chemistry ·Jérôme Hert, Peter Willett, David J. Wilton, Pierre Acklin, Khalil Azzaoui, Edgar Jacoby, Ansgar Schuffenhauer	2005	57
17	Structure and Dynamics of a Protein Assembly.1H-NMR Studies of the 36 kDaR6Insulin Hexamer Journal of Molecular Biology ·Edgar Jacoby, Qing Hua, S. A. Stern, Bruce H. Frank, Michael A. Weiss	1996	54
18	Key Aspects of the Novartis Compound Collection Enhancement Project for the Compilation of a Comprehensive Chemogenomics Drug Discovery Screening Collection Current Topics in Medicinal Chemistry ·Edgar Jacoby, Ansgar Schuffenhauer, Maxim Popov, Khalil Azzaoui, Benjamin Havill, Ulrich Schopfer, Caroline Engeloch, Jaroslav Staněk, Pierre Acklin, Pascal Rigollier, Friederike Stoll, Guido Koch, Peter Meier, David Orain, Rudolph Giger, Jurgen Hinrichs, Karine Malagu, Jurg Zimmermann, H.‐J. ROTH	2005	51
19	Biphenyls as potential mimetics of protein α-helix Bioorganic & Medicinal Chemistry Letters ·Edgar Jacoby	2002	48
20	Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53–MDM2 interaction with a distinct binding mode Bioorganic & Medicinal Chemistry Letters ·F. Gessier, Joerg Kallen, Edgar Jacoby, Patrick Chêne, Therese‐Marie Stachyra, Stephan Ruetz, Sébastien Jeay, Philipp Holzer, Keiichi Masuya, Pascal Furet	2015	47

About Edgar Jacoby

Edgar Jacoby is a scholar working on Computational Theory and Mathematics, Molecular Biology, Pharmacology, Pharmacology and Cellular and Molecular Neuroscience, having authored 88 papers that have together received 4.0k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (47 papers), Chemical Synthesis and Analysis (17 papers), Protein Structure and Dynamics (14 papers), Receptor Mechanisms and Signaling (14 papers), Microbial Natural Products and Biosynthesis (13 papers), Bioinformatics and Genomic Networks (12 papers), Genetics, Bioinformatics, and Biomedical Research (6 papers) and Monoclonal and Polyclonal Antibodies Research (5 papers). The work is most often cited by research in Computational Theory and Mathematics (2.0k citations), Molecular Biology (2.8k citations), Pharmacology (229 citations), Pharmacology (441 citations) and Spectroscopy (392 citations). Edgar Jacoby has collaborated with scholars based in Switzerland, Belgium and United States. Frequent co-authors include Ansgar Schuffenhauer, Pierre Acklin, Markus Bredel, Khalil Azzaoui, Jérôme Hert, Peter Willett, David J. Wilton, Michael Engels, Axel Wollmer and Péter Krüger. Their work appears in journals such as Journal of Chemical Information and Modeling, Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Protein Engineering Design and Selection and ACS Medicinal Chemistry Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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