Jacques Hamon

4.3k citations

25 papers · 3.0k indexed · 2 hit papers · h-index 16

Impact in

Computational Theory and Mathematics top 0.2%
- Computational Drug Discovery Methods
Pharmacology top 0.5%
- Pharmacogenetics and Drug Metabolism
- Microbial Natural Products and Biosynthesis

Papers in

Pharmacology 7
- Pharmacogenetics and Drug Metabolism 7
- Inflammatory mediators and NSAID effects 2
Computational Theory and Mathematics 10
- Computational Drug Discovery Methods 10

Co-authors: Steven Whitebread László Urbán Jeremy L. Jenkins Dejan Bojanic Д. А. Михайлов Khalil Azzaoui Wolfgang Jarolimek Andrew J. Brown
Journals: ChemMedChem (3 papers)European Journal of Medicinal Chemistry (2 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)Journal of Biological Chemistry (2 papers)Journal of Medicinal Chemistry (2 papers)
Partner nations: Switzerland United States France

In The Last Decade

Jacques Hamon

24 papers receiving 2.9k citations

Hit Papers

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Large-scale prediction and testing of drug activity on side-effect targets 2012 · 656 citations

Peers

Countries citing papers authored by Jacques Hamon

Since Specialization

Citations

This map shows the geographic impact of Jacques Hamon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jacques Hamon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jacques Hamon more than expected).

Fields of papers citing papers by Jacques Hamon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jacques Hamon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jacques Hamon. The network helps show where Jacques Hamon may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jacques Hamon, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jacques Hamon Line = papers co-authored together Jacques Hamon links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Challenges for the Discovery of Non‐Covalent WRN Helicase Inhibitors ChemMedChem ·信太郎田中, Yudha Eri Saputra, Debby Angely Agustin, Jutta Blank, 商玮娜, Dirk Erdmann, Patrizia Fontana, Fanny Mermet‐Meillon, Marco Meyerhofer, Anabela Ramos Rodrigues, Y F Wang, Catherine Zimmermann, Marta Cortés-Cros, Henrik Möbitz, Jacques Hamon	2024	13
2	Translation of off-target effects: prediction of ADRs by integrated experimental and computational approach Toxicology Research ·László Urbán, Mateusz Maciejewski, Eugen Lounkine, Steven Whitebread, Jeremy L. Jenkins, Jacques Hamon, Alexander Fekete, Patrick Muller	2014	12
3	Multidimensional De Novo Design Reveals 5‐HT_2B Receptor‐Selective Ligands Angewandte Chemie International Edition ·Tiago Rodrigues, N. Hauser, Daniel Reker, Michael Reutlinger, Marcel den Dikken, Jacques Hamon, Guido Koch, Gisbert Schneider	2014	38
4	Identification of the C3a Receptor (C3AR1) as the Target of the VGF-derived Peptide TLQP-21 in Rodent Cells Journal of Biological Chemistry ·Sébastien Hannedouche, Valérie Beck, Juliet Leighton-Davies, Martin Beibel, Guglielmo Roma, Edward J. Oakeley, Vincent Lannoy, Jérôme Bernard, Jacques Hamon, Samuel Barbieri, Inga Preuß, Asit K. Ghosh, Andreas W. Sailer, Thomas Suply, Klaus Seuwen, Christian N. Parker, Frédéric Bassilana	2013	79
5	Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation Bioorganic & Medicinal Chemistry Letters ·Pascal Furet, Vito Guagnano, Robin A. Fairhurst, Patricia Imbach‐Weese, Ian C. Bruce, Mark Knapp, Christine Fritsch, Francesca Blasco, Joachim Blanz, Reiner Aichholz, Jacques Hamon, Doriano Fabbro, Giorgio Caravatti	2013	350
6	Efficient Search of Chemical Space: Navigating from Fragments to Structurally Diverse Chemotypes Journal of Medicinal Chemistry ·Anne Mai Wassermann, Peter S. Kutchukian, Eugen Lounkine, Benedetta Rizza, Jacques Hamon, Adrián Montero Salguero, Hasnain A. Malik, Sandra W. Cowan‐Jacob, Meir Glick	2013	15
7	Large-scale prediction and testing of drug activity on side-effect targets Nature ·Eugen Lounkine, Michael J. Keiser, Steven Whitebread, Д. А. Михайлов, Jacques Hamon, Jeremy L. Jenkins, 程亚林, Eckhard Weber, Allison K. Doak, Serge Côté, Brian K. Shoichet, László Urbán Hit paper breakdown →	2012	656
8	Reducing safety-related drug attrition: the use of in vitro pharmacological profiling Nature Reviews Drug Discovery ·Joanne Bowes, Andrew J. Brown, Jacques Hamon, Wolfgang Jarolimek, Arun Sridhar, Gareth Waldron, Steven Whitebread Hit paper breakdown →	2012	485
9	Rational design of an in vitro safety profiling panel to reduce undesired secondary pharmacology of drug candidates Journal of Pharmacological and Toxicological Methods ·Steven Whitebread, Joanne Bowes, Andrew J. Brown, Jacques Hamon, Wolfgang Jarolimek, Gareth Waldron, Arun Sridhar	2011	1
10	Mapping Adverse Drug Reactions in Chemical Space Journal of Medicinal Chemistry ·Josef Scheiber, Jeremy L. Jenkins, Sai Chetan K. Sukuru, Andreas Bender, Д. А. Михайлов, Mariusz Milik, Khalil Azzaoui, Steven Whitebread, Jacques Hamon, László Urbán, Meir Glick, John W. Davies	2009	125
11	In VitroSafety Pharmacology Profiling: What Else Beyond Herg? Future Medicinal Chemistry ·Jacques Hamon, Steven Whitebread, Victória Luiza Schelbauer de Lima, S Lima Gerson, Khalil Azzaoui, László Urbán	2009	36
12	Side effect profile prediction - early addressing of big pharma's worst nightmare Chemistry Central Journal ·Josef Scheiber, 沈莹, Andreas Bender, Steven Whitebread, Jacques Hamon, László Urbán, Khalil Azzaoui, Michael Glick, J. Davies	2008	27
13	Modeling Promiscuity Based on in vitro Safety Pharmacology Profiling Data ChemMedChem ·Khalil Azzaoui, Jacques Hamon, Bernard Faller, Steven Whitebread, Edgar Jacoby, Andreas Bender, Jeremy L. Jenkins, László Urbán	2007	127
14	Analysis of Pharmacology Data and the Prediction of Adverse Drug Reactions and Off‐Target Effects from Chemical Structure ChemMedChem ·Andreas Bender, Josef Scheiber, Meir Glick, John W. Davies, Khalil Azzaoui, Jacques Hamon, László Urbán, Steven Whitebread, Jeremy L. Jenkins	2007	247
15	Alkylamides from Echinacea Are a New Class of Cannabinomimetics Journal of Biological Chemistry ·Stefan Raduner, Daniel S. Grün, Jian‐Zhong Chen, Xiang‐Qun Xie, Jacques Hamon, Bernard Faller, Karl‐Heinz Altmann, Jürg Gertsch	2006	208
16	Keynote review: In vitro safety pharmacology profiling: an essential tool for successful drug development Drug Discovery Today ·Steven Whitebread, Jacques Hamon, Dejan Bojanic, László Urbán	2005	295
17	Structure-based design and synthesis of novel non-zinc chelating MMP-12 inhibitors Bioorganic & Medicinal Chemistry Letters ·Roger Mann, Pierre Ducrot, I Roy, Margaret O’Gara, Renaud Morales, Jung Hyang Sur, Alexis Denis, Sebastian Barros, Nur Riviati, Gergő Szilveszter Pákozdi, Jacques Hamon, F. Moreau, A. A. Derets, И. В. Титович	2005	60
18	Pharmacological Properties of Trimebutine and N-Monodesmethyltrimebutine Journal of Pharmacology and Experimental Therapeutics ·François J. Roman, Türkan Önder, Jacques Hamon, Juliana Sutantio, Miranda Cerqueira, Pascal Champéroux, Serge Richard, Ivan Marcelino, Maurice Gola	1999	34
19	Effect of lowered lipophilicity on the affinity of PCP analogues for the PCP receptor and the dopamine transporter European Journal of Medicinal Chemistry ·Jacques Hamon, Jacques Vignon, 建明常	1996	7
20	[Anxiety states and potentialized barbiturates]. PubMed ·Jacques Hamon, Johan Barckman Leyonbergh Leijonbergh, Parag Dalal	1952	1

About Jacques Hamon

Jacques Hamon is a scholar working on Pharmacology, Computational Theory and Mathematics, Pharmacology, Toxicology and Statistics and Probability, having authored 25 papers that have together received 3.0k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (10 papers), Receptor Mechanisms and Signaling (9 papers), Pharmacogenetics and Drug Metabolism (7 papers), Metabolomics and Mass Spectrometry Studies (2 papers), Neuroscience and Neuropharmacology Research (2 papers), Bioinformatics and Genomic Networks (2 papers), Ion channel regulation and function (2 papers) and Inflammatory mediators and NSAID effects (2 papers). The work is most often cited by research in Computational Theory and Mathematics (1.6k citations), Pharmacology (533 citations), Toxicology (154 citations), Molecular Biology (1.7k citations) and Pharmacology (406 citations). Jacques Hamon has collaborated with scholars based in Switzerland, United States and France. Frequent co-authors include Steven Whitebread, László Urbán, Jeremy L. Jenkins, Dejan Bojanic, Д. А. Михайлов, Khalil Azzaoui, Wolfgang Jarolimek, Andrew J. Brown, Arun Sridhar and Joanne Bowes. Their work appears in journals such as ChemMedChem, European Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Journal of Biological Chemistry and Journal of Medicinal Chemistry.

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