Douglas S. Auld

11.0k total citations · 2 hit papers
120 papers, 7.1k citations indexed

About

Douglas S. Auld is a scholar working on Molecular Biology, Computational Theory and Mathematics and Biophysics. According to data from OpenAlex, Douglas S. Auld has authored 120 papers receiving a total of 7.1k indexed citations (citations by other indexed papers that have themselves been cited), including 88 papers in Molecular Biology, 19 papers in Computational Theory and Mathematics and 16 papers in Biophysics. Recurrent topics in Douglas S. Auld's work include bioluminescence and chemiluminescence research (18 papers), Computational Drug Discovery Methods (18 papers) and Cell Image Analysis Techniques (15 papers). Douglas S. Auld is often cited by papers focused on bioluminescence and chemiluminescence research (18 papers), Computational Drug Discovery Methods (18 papers) and Cell Image Analysis Techniques (15 papers). Douglas S. Auld collaborates with scholars based in United States, Switzerland and China. Douglas S. Auld's co-authors include James Inglese, Natasha Thorne, Christopher P. Austin, Anton Simeonov, Min Shen, Wei Zheng, Ronald L. Johnson, Craig J. Thomas, Ajit Jadhav and Matthew B. Boxer and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Douglas S. Auld

119 papers receiving 6.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

2011 941 citations Matthew B. Boxer, Min Shen et al. profile →
Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries

2006 623 citations James Inglese, Douglas S. Auld et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by Douglas S. Auld

Since Specialization

Citations

This map shows the geographic impact of Douglas S. Auld's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Douglas S. Auld with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Douglas S. Auld more than expected).

Fields of papers citing papers by Douglas S. Auld

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Douglas S. Auld. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Douglas S. Auld. The network helps show where Douglas S. Auld may publish in the future.

Co-authorship network of co-authors of Douglas S. Auld

This figure shows the co-authorship network connecting the top 25 collaborators of Douglas S. Auld. A scholar is included among the top collaborators of Douglas S. Auld based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Douglas S. Auld. Douglas S. Auld is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Tight-Binding Small-Molecule Carboxylesterase 2 Inhibitors Reduce Intracellular Irinotecan Activation 2024 ·Journal of Medicinal Chemistry ·(unknown), (unknown), (unknown), (unknown), Douglas S. Auld, Oleg Sadovski, (unknown), (unknown), David O. Nettleton, Mark A. Currie, Andrew A. Beharry	2
2	Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening 2021 ·Cell Reports ·Shafqat Ali Khan, Kyoung‐mi Park, Laura A. Fischer, Chen Dong, Tenzin Lungjangwa, Marta Jiménez, (unknown), (unknown), Sabine Dietmann, Douglas S. Auld, Rudolf Jaenisch, Thorold W. Theunissen	37
3	Nuisance compounds in cellular assays 2021 ·Cell chemical biology ·Jayme L. Dahlin, Douglas S. Auld, Ina Rothenaigner, (unknown), Jonathan Z. Sexton, J. Willem M. Nissink, Jarrod Walsh, Jonathan A. Lee, John Strelow, Francis S. Willard, Lori Ferrins, Jonathan B. Baell, Michael A. Walters, Bruce K. Hua, Kamyar Hadian, Bridget K. Wagner	33
4	Potent and Selective Inhibitors of 8-Oxoguanine DNA Glycosylase 2018 ·Journal of the American Chemical Society ·(unknown), Douglas S. Auld, Debin Ji, Andrew A. Beharry, Anna M. Kietrys, David L. Wilson, Marta Jiménez, Daniel King, (unknown), Eric T. Kool	59
5	Examining Ligand-Based Stabilization of Proteins in Cells with MEK1 Kinase Inhibitors 2015 ·Assay and Drug Development Technologies ·Douglas S. Auld, Christopher A. Davis, Marta Jiménez, (unknown), Jonathon P. Orme	7
6	Comparison of Compound Administration Methods in Biochemical Assays: Effects on Apparent Compound Potency Using Either Assay-Ready Compound Plates or Pin Tool–Delivered Compounds 2012 ·SLAS DISCOVERY ·Thomas M. Smith, (unknown), (unknown), Zina Itkin, (unknown), (unknown), Adam P. Hill, Douglas S. Auld	10
7	Toward Improved Therapy for Classic Galactosemia 2011 ·Europe PMC (PubMed Central) ·Matthew B. Boxer, Min Shen, Cordelle Tanega, Manshu Tang, Kent Lai, Douglas S. Auld	2
8	A Sensitive, Homogeneous, and High-Throughput Assay for Lysine-Specific Histone Demethylases at the H3K4 Site 2011 ·Assay and Drug Development Technologies ·Chunhua Wang, Mireille Caron, Debra Burdick, (unknown), Douglas S. Auld, (unknown), (unknown), Ji-Hu Zhang	8
9	Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124 2010 ·Proceedings of the National Academy of Sciences ·Douglas S. Auld, Scott Lovell, Natasha Thorne, Wendy Lea, David J. Maloney, Min Shen, Ganesha Rai, K.P. Battaile, Craig J. Thomas, Anton Simeonov, Robert P. Hanzlik, James Inglese	148
10	Improving Success by Balanced Critical Evaluations of Assay Methods 2010 ·Assay and Drug Development Technologies ·James Inglese, Andrew D. Napper, Douglas S. Auld	2
11	Identification of Pregnane X Receptor Ligands Using Time-Resolved Fluorescence Resonance Energy Transfer and Quantitative High-Throughput Screening 2009 ·Assay and Drug Development Technologies ·Sunita J. Shukla, Ðắc-Trung Nguyễn, Ryan MacArthur, Anton Simeonov, William J. Frazee, Tina M. Hallis, Bryan D. Marks, Upinder Singh, (unknown), John A. Printen, Christopher P. Austin, James Inglese, Douglas S. Auld	45
12	Comparison of Bioluminescent Kinase Assays Using Substrate Depletion and Product Formation 2009 ·Assay and Drug Development Technologies ·Cordelle Tanega, Min Shen, Bryan T. Mott, Craig J. Thomas, Ryan MacArthur, James Inglese, Douglas S. Auld	38
13	A Dual-Fluorescence High-Throughput Cell Line System for Probing Multidrug Resistance 2009 ·Assay and Drug Development Technologies ·Kyle R. Brimacombe, Matthew D. Hall, Douglas S. Auld, James Inglese, Christopher P. Austin, Michael M. Gottesman, (unknown)	46
14	A Robotic Platform for Quantitative High-Throughput Screening 2008 ·Assay and Drug Development Technologies ·Sam Michael, Douglas S. Auld, (unknown), Ajit Jadhav, Wei Zheng, Natasha Thorne, Christopher P. Austin, James Inglese, Anton Simeonov	108
15	A Cell-Based Assay for I κ B α Stabilization Using A Two-Color Dual Luciferase-Based Sensor 2007 ·Assay and Drug Development Technologies ·R. Eric Davis, Ya‐Qin Zhang, Noel Southall, Louis M. Staudt, Christopher P. Austin, James Inglese, Douglas S. Auld	21
16	High-throughput screening assays for the identification of chemical probes 2007 ·Nature Chemical Biology ·James Inglese, Ronald L. Johnson, Anton Simeonov, Menghang Xia, Wei Zheng, Christopher P. Austin, Douglas S. Auld	473
17	Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries breakdown → 2006 ·Proceedings of the National Academy of Sciences ·James Inglese, Douglas S. Auld, Ajit Jadhav, Ronald L. Johnson, Anton Simeonov, Adam Yasgar, Wei Zheng, Christopher P. Austin	623
18	1,536-Well Assay Development and Screening Using Whole Cell Displacement Binding and Laser Scanning Imaging 2003 ·Assay and Drug Development Technologies ·Douglas S. Auld, David A. Dunn, (unknown), (unknown), (unknown)	5
19	Evaluation of Compound Interference in Immobilized Metal Ion Affinity-Based Fluorescence Polarization Detection with a Four Million Member Compound Collection 2003 ·Assay and Drug Development Technologies ·James R. Beasley, David A. Dunn, (unknown), (unknown), (unknown), Douglas S. Auld	21
20	1,536-Well Assay Development and Screening Using Whole Cell Displacement Binding and Laser Scanning Imaging 2003 ·Assay and Drug Development Technologies ·Douglas S. Auld, David A. Dunn, (unknown), (unknown), (unknown)	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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