Jean M. Severin

1.4k citations

19 papers · 898 indexed · h-index 17

Co-authors: Thomas F. Holzman Stephen W. Fesik David G. Nettesheim Philip J. Hajduk Karl A. Walter Robert Meadows Edward T. Olejniczak Earl J. Gubbins
Topics: Signaling Pathways in Disease (3 papers)Peptidase Inhibition and Analysis (3 papers)Protease and Inhibitor Mechanisms (3 papers)
Cited by: Computational Theory and Mathematics Molecular Biology Oncology
Journals: Journal of the American Chemical Society Molecular Cell Biochemistry
Partner nations: United States United Kingdom Sweden

In The Last Decade

Jean M. Severin

19 papers receiving 844 citations

Peers

Countries citing papers authored by Jean M. Severin

Since Specialization

Citations

This map shows the geographic impact of Jean M. Severin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jean M. Severin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jean M. Severin more than expected).

Fields of papers citing papers by Jean M. Severin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jean M. Severin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jean M. Severin. The network helps show where Jean M. Severin may publish in the future.

Co-authorship network of co-authors of Jean M. Severin

This figure shows the co-authorship network connecting the top 25 collaborators of Jean M. Severin. A scholar is included among the top collaborators of Jean M. Severin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jean M. Severin. Jean M. Severin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

#	Work	Indexed citations
1	Magnetic Resonance Imaging Detection and Time Course of Cerebral Microhemorrhages during Passive Immunotherapy in Living Amyloid Precursor Protein Transgenic Mice 2010 ·Journal of Pharmacology and Experimental Therapeutics ·Feng Luo,Nathan R. Rustay,Terese Seifert,(unknown),Vincent P. Hradil,Heinz Hillen,Ulrich Ebert,Jean M. Severin,Bryan F. Cox,Daniel A. Llano,Mark L. Day,Gerard B. Fox	22
2	Design and characterization of an engineered gp41 protein from human immunodeficiency virus-1 as a tool for drug discovery 2007 ·Journal of Computer-Aided Molecular Design ·Kent D. Stewart,Kevin Steffy,(unknown),John E. Harlan,Vincent S. Stoll,Jeffrey R. Huth,Karl A. Walter,(unknown),Renaldo Mendoza,Jean M. Severin,Paul L. Richardson,Leo W. Barrett,Edmund D. Matayoshi,Kerry M. Swift,Stephen F. Betz,(unknown),Dale J. Kempf,Akhter Molla	4
3	Toxicological Evaluation of Thiol-Reactive Compounds Identified Using a La Assay To Detect Reactive Molecules by Nuclear Magnetic Resonance 2007 ·Chemical Research in Toxicology ·Jeffrey R. Huth,Danying Song,Renaldo Mendoza,(unknown),J. Mack,Sarah A. Dorwin,Uri S. Ladror,Jean M. Severin,Karl A. Walter,Diane M. Bartley,Philip J. Hajduk	64
4	A high throughput fluorescent assay for measuring the activity of fatty acid amide hydrolase 2006 ·Journal of Neuroscience Methods ·Karen Kage,Paul L. Richardson,Linda Traphagen,Jean M. Severin,(unknown),(unknown),Rachel Davis‐Taber,Melissa Vos,Diane M. Bartley,Karl A. Walter,John E. Harlan,Larry R. Solomon,Usha Warrior,Thomas F. Holzman,Connie R. Faltynek,Carol S. Surowy,Victoria Scott	21
5	Crystal Structures of Human Adenosine Kinase Inhibitor Complexes Reveal Two Distinct Binding Modes 2006 ·Journal of Medicinal Chemistry ·Steven W. Muchmore,Richard A. Smith,Andrew O. Stewart,Marlon Cowart,Arthur Gomtsyan,Mark A. Matulenko,Haixia Yu,Jean M. Severin,Shripad S. Bhagwat,Chih‐Hung Lee,Elizabeth A. Kowaluk,Michael F. Jarvis,(unknown)	23
6	Preparation and characterization of nitrilotriacetic-acid-terminated self-assembled monolayers on gold surfaces for matrix-assisted laser desorption ionization-time of flight-mass spectrometry analysis of proteins and peptides 2005 ·Analytical Biochemistry ·Jianwei Shen,(unknown),(unknown),Jieyi Wang,Jean M. Severin,Richard A. Smith,(unknown),Robert W. Johnson,John E. Harlan,(unknown)	18
7	Chkl binds and phosphorylates BAD protein. 2005 ·PubMed ·Edward K. Han,Christopher Butler,Haichao Zhang,Jean M. Severin,Wenying Qin,(unknown),Earl J. Gubbins,Robert L. Simmer,Saul H. Rosenberg,Vincent L. Giranda,Shi‐Chung Ng,Ying Luo	5
8	Discovery of Potent Inhibitors of Dihydroneopterin Aldolase Using CrystaLEAD High-Throughput X-ray Crystallographic Screening and Structure-Directed Lead Optimization 2004 ·Journal of Medicinal Chemistry ·William J. Sanders,V. Nienaber,Claude G. Lerner,Jennifer McCall,(unknown),(unknown),John E. Harlan,Vincent S. Stoll,(unknown),Stephen F. Betz,Kevin R. Condroski,Robert Meadows,Jean M. Severin,Karl A. Walter,(unknown),Clarissa G. Jakob,Rolf Wagner,Bruce A. Beutel	52
9	Abrogation of G2 checkpoint specifically sensitize p53 defective cells to cancer chemotherapeutic agents. 2001 ·PubMed ·Yan Luo,(unknown),Mary K. Joseph,(unknown),Christopher Butler,Stephen K. Tahir,Edward K. Han,Shi‐Chung Ng,Jean M. Severin,Earl J. Gubbins,Regina M. Reilly,(unknown),Robert L. Simmer,(unknown),Vincent L. Giranda	28
10	Structure-directed discovery of potent non-peptidic inhibitors of human urokinase that access a novel binding subsite 2000 ·Structure ·V. Nienaber,Donald J. Davidson,Rohinton Edalji,Vincent L. Giranda,Vered Klinghofer,Jack Henkin,(unknown),Robert A. Mantei,(unknown),Jean M. Severin,Richard A. Smith,Kent D. Stewart,Karl A. Walter,Jieyi Wang,Michael Wendt,Moshe Weitzberg,(unknown),Todd W. Rockway	46
11	Design of Adenosine Kinase Inhibitors from the NMR-Based Screening of Fragments 2000 ·Journal of Medicinal Chemistry ·Philip J. Hajduk,Arthur Gomtsyan,Stanley DiDomenico,Marlon Cowart,Erol K. Bayburt,Larry R. Solomon,Jean M. Severin,Richard A. Smith,Karl A. Walter,Thomas F. Holzman,Andrew O. Stewart,Steve McGaraughty,Michael F. Jarvis,Elizabeth A. Kowaluk,Stephen W. Fesik	46
12	Identification of Novel Inhibitors of Urokinase via NMR-Based Screening 2000 ·Journal of Medicinal Chemistry ·Philip J. Hajduk,Steven A. Boyd,David G. Nettesheim,V. Nienaber,Jean M. Severin,Richard A. Smith,Donald J. Davidson,Todd W. Rockway,Stephen W. Fesik	53
13	The Structure of VanX Reveals a Novel Amino-Dipeptidase Involved in Mediating Transposon-Based Vancomycin Resistance 1998 ·Molecular Cell ·Dirksen E. Bussiere,Steven Pratt,Leonard Katz,Jean M. Severin,Thomas F. Holzman,Chang H. Park	69
14	Solution structure of an rRNA methyltransferase (ErmAM) that confers macrolide-lincosamide-streptogramin antibiotic resistance 1997 ·Nature Structural Biology ·Liping Yu,Andrew M. Petros,Arndt Schnuchel,Ping Zhong,Jean M. Severin,Karl A. Walter,Thomas F. Holzman,Stephen W. Fesik	77
15	Discovery of Potent Nonpeptide Inhibitors of Stromelysin Using SAR by NMR 1997 ·Journal of the American Chemical Society ·Philip J. Hajduk,George S. Sheppard,David G. Nettesheim,Edward T. Olejniczak,Suzanne B. Shuker,Robert Meadows,Douglas H. Steinman,George M. Carrera,Patrick A. Marcotte,Jean M. Severin,K.A. Walter,(unknown),Earl J. Gubbins,Robert L. Simmer,Thomas F. Holzman,Douglas W. Morgan,Steven K. Davidsen,James B. Summers,Stephen W. Fesik	220
16	Three-dimensional structure of the FK506 binding protein/ascomycin complex in solution by heteronuclear three- and four-dimensional NMR 1993 ·Biochemistry ·Robert Meadows,David G. Nettesheim,Robert X. Xu,Edward T. Olejniczak,Andrew M. Petros,Thomas F. Holzman,Jean M. Severin,Earl J. Gubbins,(unknown),Stephen W. Fesik	62
17	High-level expression of recombinant human FK-binding protein from a fusion precursor 1992 ·Journal of Protein Chemistry ·Rohinton Edalji,Edward Tam,Steven Pratt,David A. Egan,Jean M. Severin,(unknown),Andrew M. Petros,Stephen W. Fesik,Neal S. Burres,Thomas F. Holzman	19
18	¹H,¹³C and ¹⁵N backbone assignments of cyclophilin when bound to cyclosporin A (CsA) and preliminary structural characterization of the CsA binding site 1991 ·FEBS Letters ·Placido Neri,Robert Meadows,Gerd Gemmecker,Edward T. Olejniczak,David G. Nettesheim,Timothy M. Logan,Robert L. Simmer,Rosalind Helfrich,Thomas F. Holzman,Jean M. Severin,Stephen W. Fesik	24
19	Stimulation of fibroblast proliferation and prostaglandin production by purified recombinant murine interleukin 1 1986 ·Clinical Immunology and Immunopathology ·Mitchell Dukovich,Jean M. Severin,Steven J. White,(unknown),Steven B. Mizel	45

About Jean M. Severin

Jean M. Severin is a scholar working on Cancer Research, Biotechnology and Physiology, having authored 19 papers that have together received 898 indexed citations. Recurring topics across this work include Signaling Pathways in Disease (3 papers), Peptidase Inhibition and Analysis (3 papers) and Protease and Inhibitor Mechanisms (3 papers). The work is most often cited by research in Computational Theory and Mathematics (181 citations), Molecular Biology (599 citations) and Oncology (171 citations). Jean M. Severin has collaborated with scholars based in United States, United Kingdom and Sweden. Frequent co-authors include Thomas F. Holzman, Stephen W. Fesik, David G. Nettesheim, Philip J. Hajduk, Karl A. Walter, Robert Meadows, Edward T. Olejniczak, Earl J. Gubbins, Andrew M. Petros and Robert L. Simmer. Their work appears in journals such as Journal of the American Chemical Society, Molecular Cell and Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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