John E. Harlan

7.0k total citations · 3 hit papers
40 papers, 5.8k citations indexed

About

John E. Harlan is a scholar working on Molecular Biology, Immunology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, John E. Harlan has authored 40 papers receiving a total of 5.8k indexed citations (citations by other indexed papers that have themselves been cited), including 25 papers in Molecular Biology, 11 papers in Immunology and 10 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in John E. Harlan's work include Monoclonal and Polyclonal Antibodies Research (10 papers), Cell death mechanisms and regulation (6 papers) and RNA and protein synthesis mechanisms (5 papers). John E. Harlan is often cited by papers focused on Monoclonal and Polyclonal Antibodies Research (10 papers), Cell death mechanisms and regulation (6 papers) and RNA and protein synthesis mechanisms (5 papers). John E. Harlan collaborates with scholars based in United States, Germany and United Kingdom. John E. Harlan's co-authors include Stephen W. Fesik, Ho Sup Yoon, Brian S. Chang, Craig B. Thompson, Robert Meadows, Michael Sattler, Philip J. Hajduk, Heng Liang, David G. Nettesheim and Steven W. Muchmore and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

John E. Harlan

38 papers receiving 5.6k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structure of Bcl-x _L -Bak Peptide Complex: Recognition Between Regulators of Apoptosis

1997 1.2k citations Michael Sattler, Heng Liang et al. profile →
X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

1996 1.2k citations Steven W. Muchmore, Michael Sattler et al. Nature profile →
Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

1994 656 citations John E. Harlan, Philip J. Hajduk et al. Nature profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
John E. Harlan	4.5k	899	836	746	693	40	5.8k
Jenny Bain	5.5k 1.2×	613 0.7×	1.0k 1.2×	702 0.9×	572 0.8×	29	7.4k
Lawrence C. Fritz	3.6k 0.8×	985 1.1×	811 1.0×	503 0.7×	1.5k 2.1×	33	6.0k
Igor F. Tsigelny	3.0k 0.7×	539 0.6×	807 1.0×	439 0.6×	351 0.5×	166	5.4k
Maria Ruzzene	4.5k 1.0×	273 0.3×	1.1k 1.3×	665 0.9×	541 0.8×	120	6.1k
Nicola Zambrano	2.9k 0.7×	1.4k 1.5×	848 1.0×	609 0.8×	271 0.4×	107	4.3k
Marketa Zvelebil	5.8k 1.3×	515 0.6×	1.6k 1.9×	1.2k 1.6×	1.1k 1.6×	102	8.2k
Holger Rehmann	5.1k 1.1×	791 0.9×	566 0.7×	1.7k 2.3×	366 0.5×	75	7.2k
Claude Cochet	5.8k 1.3×	381 0.4×	1.9k 2.3×	1.0k 1.4×	540 0.8×	191	8.1k
E G Krebs	5.4k 1.2×	552 0.6×	555 0.7×	1.1k 1.5×	536 0.8×	31	6.7k
Carson R. Loomis	4.2k 0.9×	754 0.8×	331 0.4×	851 1.1×	416 0.6×	35	5.4k

Countries citing papers authored by John E. Harlan

Since Specialization

Citations

This map shows the geographic impact of John E. Harlan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John E. Harlan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John E. Harlan more than expected).

Fields of papers citing papers by John E. Harlan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John E. Harlan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John E. Harlan. The network helps show where John E. Harlan may publish in the future.

Co-authorship network of co-authors of John E. Harlan

This figure shows the co-authorship network connecting the top 25 collaborators of John E. Harlan. A scholar is included among the top collaborators of John E. Harlan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John E. Harlan. John E. Harlan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ye, Shiming, Nicole A. Belmar, Mien Sho, et al.. (2019). A Bispecific Molecule Targeting CD40 and Tumor Antigen Mesothelin Enhances Tumor-Specific Immunity. Cancer Immunology Research. 7(11). 1864–1875. 40 indexed citations

Guo, Jun, Xiao Yu, Xin Lü, et al.. (2019). Empowering therapeutic antibodies with IFN-α for cancer immunotherapy. PLoS ONE. 14(8). e0219829–e0219829. 20 indexed citations

Argiriadi, M.A., Lorenzo Benatuil, David A. Egan, et al.. (2019). CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches. BMC Molecular and Cell Biology. 20(1). 29–29. 19 indexed citations

Harlan, John E., et al.. (2017). Observations of Xyleborus affinis Eichhoff (Coleoptera:Curculionidae:Scolytinae) in Central Michigan. The Great Lakes Entomologist. 48(3). 6 indexed citations

DiGiammarino, Enrico L., John E. Harlan, Karl A. Walter, et al.. (2011). Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design. mAbs. 3(5). 487–494. 34 indexed citations

Ansell, Peter, Haiying Zhang, Donald J. Davidson, et al.. (2010). Recombinant kringle 5 from plasminogen antagonises hepatocyte growth factor-mediated signalling. European Journal of Cancer. 46(5). 966–973. 5 indexed citations

Flentge, Charles A., John T. Randolph, Peggy Huang, et al.. (2009). Synthesis and evaluation of inhibitors of cytochrome P450 3A (CYP3A) for pharmacokinetic enhancement of drugs. Bioorganic & Medicinal Chemistry Letters. 19(18). 5444–5448. 9 indexed citations

Luo, Feng, Terese Seifert, Rohinton Edalji, et al.. (2008). Non-invasive characterization of β-amyloid1-40 vasoactivity by functional magnetic resonance imaging in mice. Neuroscience. 155(1). 263–269. 19 indexed citations

Kage, Karen, Paul L. Richardson, Linda Traphagen, et al.. (2006). A high throughput fluorescent assay for measuring the activity of fatty acid amide hydrolase. Journal of Neuroscience Methods. 161(1). 47–54. 21 indexed citations

10.

Shen, Jianwei, Jieyi Wang, Jean M. Severin, et al.. (2005). Preparation and characterization of nitrilotriacetic-acid-terminated self-assembled monolayers on gold surfaces for matrix-assisted laser desorption ionization-time of flight-mass spectrometry analysis of proteins and peptides. Analytical Biochemistry. 345(2). 258–269. 18 indexed citations

11.

Johnson, Robert W., Rohinton Edalji, Richard Smith, et al.. (2005). Protein fragmentation via liquid chromatography–quadrupole time-of-flight mass spectrometry: The use of limited sequence information in structural characterization. Analytical Biochemistry. 341(1). 22–32. 7 indexed citations

12.

Barghorn, Stefan, Volker Nimmrich, Andreas Striebinger, et al.. (2005). Globular amyloid β‐peptide₁₋₄₂ oligomer − a homogenous and stable neuropathological protein in Alzheimer's disease. Journal of Neurochemistry. 95(3). 834–847. 471 indexed citations

13.

Harlan, John E., David A. Egan, Uri S. Ladror, et al.. (2003). Driving Affinity Selection by Centrifugal Force. Assay and Drug Development Technologies. 1(4). 507–519. 6 indexed citations

14.

Kauppi, Björn, Clarissa G. Jakob, Mathias Färnegårdh, et al.. (2003). The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain. Journal of Biological Chemistry. 278(25). 22748–22754. 277 indexed citations

15.

Liu, Xiaohong, Hong Wang, Matthias Eberstadt, et al.. (1998). NMR Structure and Mutagenesis of the N-Terminal Dbl Homology Domain of the Nucleotide Exchange Factor Trio. Cell. 95(2). 269–277. 151 indexed citations

16.

Muchmore, Steven W., Michael Sattler, Heng Liang, et al.. (1996). X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death. Nature. 381(6580). 335–341. 1199 indexed citations breakdown →

17.

Zhou, Ming‐Ming, John E. Harlan, Warren S. Wade, et al.. (1995). Binding Affinities of Tyrosine-phosphorylated Peptides to the COOH-terminal SH2 and NH2-terminal Phosphotyrosine Binding Domains of Shc. Journal of Biological Chemistry. 270(52). 31119–31123. 49 indexed citations

18.

Zhou, Ming‐Ming, Kodi S. Ravichandran, Edward T. Olejniczak, et al.. (1995). Structure and ligand recognition of the phosphotyrosine binding domain of Shc. Nature. 378(6557). 584–592. 309 indexed citations

19.

Harlan, John E., Ho Sup Yoon, Philip J. Hajduk, & Stephen W. Fesik. (1995). Structural Characterization of the Interaction between a Pleckstrin Homology Domain and Phosphatidylinositol 4,5-Bisphosphate. Biochemistry. 34(31). 9859–9864. 106 indexed citations

20.

Harlan, John E., Philip J. Hajduk, Ho Sup Yoon, & Stephen W. Fesik. (1994). Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate. Nature. 371(6493). 168–170. 656 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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