Steven M. Hersch

17.4k citations

129 papers · 12.6k indexed · 5 hit papers · h-index 55

Impact in

Cellular and Molecular Neuroscience top 0.05%
- Genetic Neurodegenerative Diseases
- Neuroscience and Neuropharmacology Research
Neurology top 0.1%
- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments

Papers in

Cellular and Molecular Neuroscience 104
- Genetic Neurodegenerative Diseases 86
- Neuroscience and Neuropharmacology Research 15
Neurology 45
- Neurological disorders and treatments 36
- Parkinson's Disease Mechanisms and Treatments 12

Co-authors: Robert J. Ferrante Claire‐Anne Gutekunst H. Diana Rosas Allan I. Levey Edward L. White Hong Yi Stefan Kuemmerle James K. Kubilus
Journals: Journal of Neuroscience (11 papers)The Journal of Comparative Neurology (10 papers)Neurology (8 papers)Proceedings of the National Academy of Sciences (7 papers)Journal of Biological Chemistry (5 papers)
Partner nations: United States United Kingdom Switzerland

In The Last Decade

Steven M. Hersch

125 papers receiving 12.4k citations

Hit Papers

5 papers align trajectories log scale

Updated safety results from phase 3 lecanemab study in early Alzheimer’s disease 2024 · 61 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2024 Alzheimer s Research & Therapy
2003 Journal of Neuroscience
2002 Science
1999 Journal of Neuroscience
1999 Neuron

Peers

Countries citing papers authored by Steven M. Hersch

Since Specialization

Citations

This map shows the geographic impact of Steven M. Hersch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Steven M. Hersch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Steven M. Hersch more than expected).

Fields of papers citing papers by Steven M. Hersch

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Steven M. Hersch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Steven M. Hersch. The network helps show where Steven M. Hersch may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Steven M. Hersch, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Steven M. Hersch Line = papers co-authored together Steven M. Hersch links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Lecanemab‐Associated Amyloid‐β Protofibril in Cerebrospinal Fluid Correlates with Biomarkers of Neurodegeneration in Alzheimer's Disease Annals of Neurology ·Moeko Noguchi‐Shinohara, 国富朱, Zhe Long-xuan, Yukiko Mori, Junji Komatsu, 한선영, Steven M. Hersch, Kanta Horie, Kenjiro Ono	2025	3
2	"Paradoxical” Cerebral Volume Changes in Anti‐Amyloid Immunotherapy Trials Alzheimer s & Dementia ·Nick C. Fox, Arnaud Charil, Perminder S. Sachdev, Hongmei Niu, Michael C. Irizarry, Steven M. Hersch, Larisa Reyderman	2024	1
3	Lecanemab Slows Tau PET Accumulation Alzheimer s & Dementia ·Arnaud Charil, Youfang Cao, Brian A. Willis, Steven M. Hersch, Michael C. Irizarry, Larisa Reyderman	2024	3
4	Lecanemab Clarity AD: Quality-of-Life Results from a Randomized, Double-Blind Phase 3 Trial in Early Alzheimer's Disease The Journal of Prevention of Alzheimer s Disease ·Sarah Cohen, Christopher H. van Dyck, Michelle Gee, T. Doherty, Michio Kanekiyo, Shobha Dhadda, David K.B. Li, Steven M. Hersch, Michael C. Irizarry, L. D. Kramer	2023	50
5	Isolated ARIA-H in patients treated with lecanemab in the phase 3 clarity AD study in early Alzheimer's disease Journal of the Neurological Sciences ·Marwan N. Sabbagh, Jeffrey L. Cummings, Bertomeu Muñoz Vázquez, Steven M. Hersch, Michio Kanekiyo, Shobha Dhadda, Michael C. Irizarry, Lynn D. Kramer, Lawrence S. Honig	2023	1
6	Altered selenium status in Huntington's disease: Neuroprotection by selenite in the N171-82Q mouse model Neurobiology of Disease ·Zhen Lu, Eileen Marks, Jianfang Chen, Farzad A. Amiri, S Vinoth, Merl F. Raisbeck, Irene Volitakis, Robert A. Cherny, Vanita Chopra, Ashley I. Bush, Steven M. Hersch, Jonathan H. Fox	2014	44
7	Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine PLoS ONE ·Jianfang Chen, Eileen Marks, Barry Lai, Zhaojie Zhang, James A. Duce, Linh Q. Lam, Irene Volitakis, Ashley I. Bush, Steven M. Hersch, Jonathan H. Fox	2013	144
8	Plasma 8-hydroxy-2′-deoxyguanosine Levels in Huntington Disease and Healthy Controls Treated with Coenzyme Q10 Journal of Huntington s Disease ·Kevin Biglan, (unknown), E. Ray Dorsey, JEREMY H. CARROLL, Christopher A. Ross, Steven M. Hersch, Ira Shoulson, Wayne R. Matson, Karl Kieburtz	2012	9
9	Transcriptional modulator H2A histone family, member Y ( H2AFY ) marks Huntington disease activity in man and mouse Proceedings of the National Academy of Sciences ·Yi Hu, Vanita Chopra, Raman Chopra, Joseph J. Locascio, Zhixiang Liao, Hongliu Ding, Bin Zheng, Wayne R. Matson, Robert J. Ferrante, H. Diana Rosas, Steven M. Hersch, Clemens R. Scherzer	2011	76
10	The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease Molecular Neurodegeneration ·Jonathan H. Fox, Markus Kaiser, Vanita Chopra, T.A. Youngs, Jibrin Kama, Dorothée Bleckmann, Claudia Betschart, Daniël Hoyer, Stefan Frentzel, Marian DiFiglia, Paolo Paganetti, Steven M. Hersch	2010	76
11	Complexity and Heterogeneity: What Drives the Ever‐changing Brain in Huntington's Disease? Annals of the New York Academy of Sciences ·H. Diana Rosas, David H. Salat, Stephanie Y. Lee, Alexandra K. Zaleta, Nathanael D. Hevelone, Steven M. Hersch	2008	39
12	Neuroprotective Effects of Synaptic Modulation in Huntington's Disease R6/2 Mice Journal of Neuroscience ·Edward C. Stack, Alpaslan Dedeoglu, Karen Smith, Kerry Cormier, James K. Kubilus, Mikhail Bogdanov, Wayne R. Matson, Lichuan Yang, Bruce G. Jenkins, Ruth Luthi‐Carter, Neil W. Kowall, Steven M. Hersch, M. Flint Beal, Robert J. Ferrante	2007	61
13	Discovery of Bioactive Small-Molecule Inhibitor of Poly ADP-Ribose Polymerase: Implications for Energy-Deficient Cells Chemistry & Biology ·Stephen M. Altmann, Carol Morgan, Elisa Fossale, Michele M. Maxwell, D. Nafai-Boutouchent, Jonathan H. Fox, Steven M. Hersch, Anne B. Young, Marcy E. MacDonald, Ruben Abagyan, Aleksey Kazantsev	2006	8
14	Translating therapies for Huntington’s disease from genetic animal models to clinical trials Neurotherapeutics ·Steven M. Hersch, Robert J. Ferrante	2004	2
15	Translating therapies for Huntington’s disease from genetic animal models to clinical trials PubMed ·Steven M. Hersch, Robert J. Ferrante	2004	55
16	Huntington's disease Current Opinion in Neurology ·Steven M. Hersch	2003	19
17	Recent advances in Huntingtonʼs disease Current Opinion in Neurology ·Claire‐Anne Gutekunst, D. Nafai-Boutouchent, Steven M. Hersch	2000	23
18	A Human HAP1 Homologue Journal of Biological Chemistry ·Shihua Li, Seyed Hamzeh Hosseini, Claire‐Anne Gutekunst, Steven M. Hersch, Robert J. Ferrante, Xiao‐Jiang Li	1998	64
19	Heterogeneous Topographic and Cellular Distribution of Huntingtin Expression in the Normal Human Neostriatum Journal of Neuroscience ·Robert J. Ferrante, Tian Zhao-ming, Francesca Persichetti, Sandra McNeil, Neil W. Kowall, and K Viswanath, Marcy E. MacDonald, Juan C Valderrama Z, Steven M. Hersch	1997	117
20	Fragile X Mental Retardation Protein: Nucleocytoplasmic Shuttling and Association with Somatodendritic Ribosomes Journal of Neuroscience ·Yue Feng, Claire‐Anne Gutekunst, Derek E. Eberhart, Hong Yi, Stephen T. Warren, Steven M. Hersch	1997	430

About Steven M. Hersch

Steven M. Hersch is a scholar working on Cellular and Molecular Neuroscience, Neurology, Molecular Biology, Structural Biology and Cognitive Neuroscience, having authored 129 papers that have together received 12.6k indexed citations. Recurring topics across this work include Genetic Neurodegenerative Diseases (86 papers), Mitochondrial Function and Pathology (60 papers), Neurological disorders and treatments (36 papers), Muscle Physiology and Disorders (15 papers), Neuroscience and Neuropharmacology Research (15 papers), Parkinson's Disease Mechanisms and Treatments (12 papers), Ubiquitin and proteasome pathways (10 papers) and Neural dynamics and brain function (10 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (8.9k citations), Neurology (3.7k citations), Molecular Biology (8.5k citations), Biological Psychiatry (196 citations) and Geriatrics and Gerontology (278 citations). Steven M. Hersch has collaborated with scholars based in United States, United Kingdom and Switzerland. Frequent co-authors include Robert J. Ferrante, Claire‐Anne Gutekunst, H. Diana Rosas, Allan I. Levey, Edward L. White, Hong Yi, Stefan Kuemmerle, James K. Kubilus, Alpaslan Dedeoglu and M. Flint Beal. Their work appears in journals such as Journal of Neuroscience, The Journal of Comparative Neurology, Neurology, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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