Shiang-Yuan Chen

1.1k total citations · 1 hit paper
12 papers, 845 citations indexed

About

Shiang-Yuan Chen is a scholar working on Oncology, Pharmacology and Biochemistry. According to data from OpenAlex, Shiang-Yuan Chen has authored 12 papers receiving a total of 845 indexed citations (citations by other indexed papers that have themselves been cited), including 4 papers in Oncology, 4 papers in Pharmacology and 4 papers in Biochemistry. Recurrent topics in Shiang-Yuan Chen's work include Pharmacogenetics and Drug Metabolism (4 papers), Drug Transport and Resistance Mechanisms (3 papers) and Amino Acid Enzymes and Metabolism (2 papers). Shiang-Yuan Chen is often cited by papers focused on Pharmacogenetics and Drug Metabolism (4 papers), Drug Transport and Resistance Mechanisms (3 papers) and Amino Acid Enzymes and Metabolism (2 papers). Shiang-Yuan Chen collaborates with scholars based in United States and Germany. Shiang-Yuan Chen's co-authors include Nirmala Raghavan, Donglu Zhang, Kan He, Samuel J. Bonacorsi, Haiying Zhang, Donald Pinto, W. Griffith Humphreys, Pancras C. Wong, Charles Frost and Zhigang Yu and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Medicinal Chemistry and The Journal of Organic Chemistry.

In The Last Decade

Shiang-Yuan Chen

12 papers receiving 811 citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Apixaban Metabolism and Pharmacokinetics after Oral Administration to Humans

2008 490 citations Nirmala Raghavan, Charles Frost et al. Drug Metabolism and Disposition profile →

Peers

Countries citing papers authored by Shiang-Yuan Chen

Since Specialization

Citations

This map shows the geographic impact of Shiang-Yuan Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shiang-Yuan Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shiang-Yuan Chen more than expected).

Fields of papers citing papers by Shiang-Yuan Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shiang-Yuan Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shiang-Yuan Chen. The network helps show where Shiang-Yuan Chen may publish in the future.

Co-authorship network of co-authors of Shiang-Yuan Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Shiang-Yuan Chen. A scholar is included among the top collaborators of Shiang-Yuan Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shiang-Yuan Chen. Shiang-Yuan Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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12 of 12 papers shown

#	Work	Indexed citations
1	In Vitro Assessment of Metabolic Drug-Drug Interaction Potential of Apixaban through Cytochrome P450 Phenotyping, Inhibition, and Induction Studies 2009 ·Drug Metabolism and Disposition ·Lifei Wang, Donglu Zhang, Nirmala Raghavan, Ming Yao, Li Ma, Chris Frost, Brad D. Maxwell, Shiang-Yuan Chen, Kan He, Theunis C. Goosen, Wendell H. Griffith, Scott Grossman	212
2	Apixaban Metabolism and Pharmacokinetics after Oral Administration to Humans breakdown → 2008 ·Drug Metabolism and Disposition ·Nirmala Raghavan, Charles Frost, Zhigang Yu, Kan He, Haiying Zhang, W. Griffith Humphreys, Donald Pinto, Shiang-Yuan Chen, Samuel J. Bonacorsi, Pancras C. Wong, Donglu Zhang	490
3	Reductive Isoxazole Ring Opening of the Anticoagulant Razaxaban Is the Major Metabolic Clearance Pathway in Rats and Dogs 2007 ·Drug Metabolism and Disposition ·Donglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi L. Quan, (unknown), (unknown), Patrick Y. S. Lam, Samuel J. Bonacorsi, Robert M. Knabb, Gary L. Skiles, Kan He	46
4	Bioactivation of Benzylamine to Reactive Intermediates in Rodents: Formation of Glutathione, Glutamate, and Peptide Conjugates 2002 ·Chemical Research in Toxicology ·Abdul Mutlib, (unknown), Shiang-Yuan Chen, Robert Espina, J. Scott Daniels, Liang‐Shang Gan	24
5	Disposition of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2‘- (methylsulfonyl)-[1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)- 1H-pyrazole-5-carboxamide (DPC 423) by Novel Metabolic Pathways. Characterization of Unusual Metabolites by Liquid Chromatography/Mass Spectrometry and NMR 2001 ·Chemical Research in Toxicology ·Abdul Mutlib, John P. Shockcor, Shiang-Yuan Chen, Robert Espina, Donald Pinto, Michael J. Orwat, Shimoga R. Prakash, Liang‐Shang Gan	21
6	P450-Mediated Metabolism of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2‘-(methylsulfonyl)- [1,1‘-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole- 5-carboxamide (DPC 423) and Its Analogues to Aldoximes. Characterization of Glutathione Conjugates of Postulated Intermediates Derived from Aldoximes 2001 ·Chemical Research in Toxicology ·Abdul Mutlib, Shiang-Yuan Chen, Robert Espina, John P. Shockcor, Shimoga R. Prakash, Liang‐Shang Gan	19
7	Chemical Mechanism of the Covalent Modification of 5.alpha.-Reductases by Finasteride as Probed by Secondary Tritium Isotope Effects 1995 ·Journal of the American Chemical Society ·Gaochao Tian, Shiang-Yuan Chen, Kevin L. Facchine, Shimoga R. Prakash	11
8	Application of nitrogen-15 NMR spectroscopy in structural studies of trimethylsilyl derivatives of lactams 1982 ·Journal of Magnetic Resonance (1969) ·(unknown), Surendra P. Gupta, Shiang-Yuan Chen	2
9	Folate analogs altered in the C9-N10 bridge region. 14. 11-Oxahomofolic acid, a potential antitumor agent 1980 ·Journal of Medicinal Chemistry ·Muraleedharan G. Nair, (unknown), Shiang-Yuan Chen, Roy L. Kisliuk, Y. Gaumont	9
10	Folate analogs altered in the C9-N10 bridge region. 16. Synthesis and antifolate activity of 11-thiohomoaminopterin 1980 ·Journal of Medicinal Chemistry ·Muraleedharan G. Nair, Shiang-Yuan Chen, Roy L. Kisliuk, Y. Gaumont, Dan Strumpf	5
11	Folate analogs altered in the C9-N10 bridge region: 11-thiohomofolic acid 1979 ·Journal of Medicinal Chemistry ·Muraleedharan G. Nair, Shiang-Yuan Chen, Roy L. Kisliuk, Y. Gaumont, Dan Strumpf	5
12	Rearrangement reaction of 1-chloro-4-[p-(carbomethoxy)thiophenoxy]-2-butanone with potassium phthalimide 1978 ·The Journal of Organic Chemistry ·Shiang-Yuan Chen, Muraleedharan G. Nair	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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