Jan Bieschke

7.5k total citations · 3 hit papers
56 papers, 6.0k citations indexed

About

Jan Bieschke is a scholar working on Molecular Biology, Physiology and Neurology. According to data from OpenAlex, Jan Bieschke has authored 56 papers receiving a total of 6.0k indexed citations (citations by other indexed papers that have themselves been cited), including 33 papers in Molecular Biology, 30 papers in Physiology and 13 papers in Neurology. Recurrent topics in Jan Bieschke's work include Alzheimer's disease research and treatments (28 papers), Prion Diseases and Protein Misfolding (21 papers) and Neurological diseases and metabolism (11 papers). Jan Bieschke is often cited by papers focused on Alzheimer's disease research and treatments (28 papers), Prion Diseases and Protein Misfolding (21 papers) and Neurological diseases and metabolism (11 papers). Jan Bieschke collaborates with scholars based in United States, Germany and United Kingdom. Jan Bieschke's co-authors include Erich E. Wanker, Jeffery W. Kelly, Dagmar E. Ehrnhoefer, Heike J. Wobst, Rudi Lurz, Annett Boeddrich, Martin Herbst, Ralf P. Friedrich, Andrew Dillin and Ehud Cohen and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Jan Bieschke

53 papers receiving 5.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

2008 1.2k citations Dagmar E. Ehrnhoefer, Jan Bieschke et al. Nature Structural & Molecular Biology profile →
EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

2010 853 citations Jan Bieschke, Ralf P. Friedrich et al. Proceedings of the National Academy of Sciences profile →
Opposing Activities Protect Against Age-Onset Proteotoxicity

2006 687 citations Ehud Cohen, Jan Bieschke et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jan Bieschke United States	32	3.1k	3.1k	809	613	562	56	6.0k
Cristina Cecchi Italy	36	2.4k 0.8×	2.4k 0.8×	889 1.1×	353 0.6×	505 0.9×	97	4.3k
Dagmar E. Ehrnhoefer Canada	22	1.8k 0.6×	2.0k 0.6×	827 1.0×	372 0.6×	1.2k 2.1×	34	4.0k
Monica Bucciantini Italy	31	2.5k 0.8×	3.7k 1.2×	443 0.5×	292 0.5×	412 0.7×	87	5.6k
Harry LeVine United States	36	3.3k 1.1×	2.6k 0.8×	359 0.4×	776 1.3×	536 1.0×	72	5.3k
Gunnar Brinkmalm Sweden	39	3.2k 1.0×	2.2k 0.7×	576 0.7×	441 0.7×	638 1.1×	134	5.4k
Eduardo M. Castaño Argentina	33	3.8k 1.2×	2.5k 0.8×	468 0.6×	684 1.1×	585 1.0×	73	4.9k
László Ötvös United States	39	3.9k 1.3×	4.1k 1.3×	398 0.5×	802 1.3×	1.1k 1.9×	97	7.9k
Per Hammarström Sweden	45	3.2k 1.0×	4.5k 1.5×	397 0.5×	425 0.7×	381 0.7×	145	7.2k
Miguel Calero Spain	39	3.3k 1.1×	2.9k 1.0×	759 0.9×	581 0.9×	747 1.3×	132	6.5k
Katsuhiko Yanagisawa Japan	51	5.9k 1.9×	4.9k 1.6×	527 0.7×	784 1.3×	1.2k 2.1×	144	9.1k

Countries citing papers authored by Jan Bieschke

Since Specialization

Citations

This map shows the geographic impact of Jan Bieschke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jan Bieschke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jan Bieschke more than expected).

Fields of papers citing papers by Jan Bieschke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jan Bieschke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jan Bieschke. The network helps show where Jan Bieschke may publish in the future.

Co-authorship network of co-authors of Jan Bieschke

This figure shows the co-authorship network connecting the top 25 collaborators of Jan Bieschke. A scholar is included among the top collaborators of Jan Bieschke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jan Bieschke. Jan Bieschke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Hill, Elizabeth, Mark Batchelor, Juan M. Ribes, et al.. (2024). Syntaxin-6 delays prion protein fibril formation and prolongs the presence of toxic aggregation intermediates. eLife. 13. 2 indexed citations

Hosszu, Laszlo L. P., Mark Batchelor, Emmanuel Risse, et al.. (2023). Loss of Residues 119–136, Including the First β-strand of Human Prion Protein, Generates an Aggregation-competent Partially “Open” Form. Journal of Molecular Biology. 435(15). 168158–168158.

Nahass, George R., Yong Xu, Mark Batchelor, et al.. (2021). Brazilin Removes Toxic Alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium. Journal of Molecular Biology. 433(8). 166878–166878. 8 indexed citations

Hosszu, Laszlo L. P., Rebecca Conners, Mark Batchelor, et al.. (2020). Structural effects of the highly protective V127 polymorphism on human prion protein. Communications Biology. 3(1). 402–402. 7 indexed citations

Bieschke, Jan, et al.. (2016). Unconventional Chaperone Inhibits Amyloid Formation by Promoting off-Pathway Aggregation. Biophysical Journal. 110(3). 551a–552a. 1 indexed citations

Jin, Sha, Niraja Kedia, Eva Illes‐Toth, et al.. (2016). Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity. Journal of Biological Chemistry. 291(37). 19590–19606. 91 indexed citations

Hegenbart, Ute, Christoph Kimmich, Niraja Kedia, et al.. (2016). Aggregation of Full-length Immunoglobulin Light Chains from Systemic Light Chain Amyloidosis (AL) Patients Is Remodeled by Epigallocatechin-3-gallate. Journal of Biological Chemistry. 292(6). 2328–2344. 36 indexed citations

Bieschke, Jan, et al.. (2015). The Effect of (−)-Epigallo-catechin-(3)-gallate on Amyloidogenic Proteins Suggests a Common Mechanism. Advances in experimental medicine and biology. 863. 139–161. 60 indexed citations

Bieschke, Jan, et al.. (2014). Aggregation in AL Amyloidosis. Biophysical Journal. 106(2). 58a–58a. 1 indexed citations

10.

Wobst, Heike J., Apurwa M Sharma, Marc I. Diamond, Erich E. Wanker, & Jan Bieschke. (2014). The green tea polyphenol (−)‐epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios. FEBS Letters. 589(1). 77–83. 164 indexed citations

11.

Bieschke, Jan. (2013). Natural Compounds May Open New Routes to Treatment of Amyloid Diseases. Neurotherapeutics. 10(3). 429–439. 71 indexed citations

12.

Amo, Juan Miguel López del, Uwe Fink, Muralidhar Dasari, et al.. (2012). Structural Properties of EGCG-Induced, Nontoxic Alzheimer's Disease Aβ Oligomers. Journal of Molecular Biology. 421(4-5). 517–524. 138 indexed citations

13.

Sommer, Andrei P., Jan Bieschke, Ralf P. Friedrich, et al.. (2011). 670 nm Laser Light and EGCG Complementarily Reduce Amyloid-β Aggregates in Human Neuroblastoma Cells: Basis for Treatment of Alzheimer's Disease?. Photomedicine and Laser Surgery. 30(1). 54–60. 59 indexed citations

14.

Bieschke, Jan, Martin Herbst, Thomas Wiglenda, et al.. (2011). Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils. Nature Chemical Biology. 8(1). 93–101. 386 indexed citations

15.

Ehrnhoefer, Dagmar E., Jan Bieschke, Annett Boeddrich, et al.. (2008). EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers. Nature Structural & Molecular Biology. 15(6). 558–566. 1191 indexed citations breakdown →

16.

Cohen, Ehud, et al.. (2006). Opposing Activities Protect Against Age-Onset Proteotoxicity. Science. 313(5793). 1604–1610. 687 indexed citations breakdown →

17.

Giese, Armin, Benedikt Bader, Jan Bieschke, et al.. (2005). Single particle detection and characterization of synuclein co-aggregation. Biochemical and Biophysical Research Communications. 333(4). 1202–1210. 39 indexed citations

18.

Sarafoff, Nikolaus, Jan Bieschke, Armin Giese, et al.. (2005). Automated PrPres amplification using indirect sonication. Journal of Biochemical and Biophysical Methods. 63(3). 213–221. 13 indexed citations

19.

Koltermann, Andre, Ulrich Kettling, Jan Bieschke, T. Winkler, & Manfred Eigen. (1998). Rapid assay processing by integration of dual-color fluorescence cross-correlation spectroscopy: High throughput screening for enzyme activity. Proceedings of the National Academy of Sciences. 95(4). 1421–1426. 111 indexed citations

20.

Schwille, Petra, et al.. (1997). Kinetic investigations by fluorescence correlation spectroscopy: The analytical and diagnostic potential of diffusion studies. Biophysical Chemistry. 66(2-3). 211–228. 129 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact