Jan Näslund

8.6k citations

51 papers · 7.0k indexed · 4 hit papers · h-index 30

Impact in

Physiology top 0.2%
- Alzheimer's disease research and treatments
Biological Psychiatry top 2%

Papers in

Physiology 46
- Alzheimer's disease research and treatments 46
Pharmacology 10
- Cholinesterase and Neurodegenerative Diseases 9

Co-authors: Lars O. Tjernberg Christer Nordstedt Lars Terenius Johan Thyberg Bengt Winblad Lars Lannfelt Anders R. Karlström Paul Greengard
Journals: Journal of Biological Chemistry (18 papers)Journal of Neurochemistry (4 papers)Proceedings of the National Academy of Sciences (2 papers)FEBS Letters (2 papers)Neurobiology of Aging (2 papers)
Partner nations: Sweden United States Japan

In The Last Decade

Jan Näslund

51 papers receiving 6.9k citations

Hit Papers

align trajectories log scale

The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Aβ protofibril formation 2001 · 943 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2001 Nature Neuroscience
2000 American Journal Of Pathology
2000 JAMA
1996 Journal of Biological Chemistry

Peers

Countries citing papers authored by Jan Näslund

Since Specialization

Citations

This map shows the geographic impact of Jan Näslund's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jan Näslund with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jan Näslund more than expected).

Fields of papers citing papers by Jan Näslund

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jan Näslund. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jan Näslund. The network helps show where Jan Näslund may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jan Näslund, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jan Näslund Line = papers co-authored together Jan Näslund links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Mutations in Nicastrin Protein Differentially Affect Amyloid β-Peptide Production and Notch Protein Processing Journal of Biological Chemistry ·F. Rietz, Johanna Wanngren, Lars O. Tjernberg, Bengt Winblad, Ratan V. Bhat, Jan Näslund, Helena Karlström	2011	15
2	Amyloid neuropathology in the single Arctic APP transgenic model affects interconnected brain regions Neurobiology of Aging ·Annica Rönnbäck, Tarek Alkhoury, Sebastián Amézquita Vargas, Jan Näslund, Gunilla T. Westermark, Bengt Winblad, Caroline Graff	2011	38
3	The Large Hydrophilic Loop of Presenilin 1 Is Important for Regulating γ-Secretase Complex Assembly and Dictating the Amyloid β Peptide (Aβ) Profile without Affecting Notch Processing Journal of Biological Chemistry ·Johanna Wanngren, Jenny Frånberg, J.P Kim, Hanna Laudon, Fredrik Olsson, Bengt Winblad, Xiaodong Liu, Jan Näslund, Johan Lundkvist, Helena Karlström	2010	13
4	The Alzheimer's disease-associated γ-secretase complex: Functional domains in the presenilin 1 protein Physiology & Behavior ·Hanna Laudon, Bengt Winblad, Jan Näslund	2007	14
5	Unwinding fibril formation of medin, the peptide of the most common form of human amyloid Biochemical and Biophysical Research Communications ·Annika Sundås Larsson, Linda Söderberg, Gunilla T. Westermark, Knut Sletten, Ulla Engström, Lars O. Tjernberg, Jan Näslund, Per Westermark	2007	33
6	Elevated cortical zinc in Alzheimer disease Neurology ·Dorota Religa, (unknown), Robert A. Cherny, Irene Volitakis, V. Haroutunian, Bengt Winblad, Jan Näslund, Ashley I. Bush	2006	223
7	Attenuation of Aβ deposition in the entorhinal cortex of normal elderly individuals associated with tobacco smoking Neuropathology and Applied Neurobiology ·J.A. Court, Michele H. Johnson, Dorota Religa, Z. Wang, Rajesh Kalaria, Evelyn Jaros, Ian G. McKeith, Robert Perry, Jan Näslund, Elaine K. Perry	2005	24
8	A Nine-transmembrane Domain Topology for Presenilin 1 Journal of Biological Chemistry ·Hanna Laudon, Emil M. Hansson, Karin Melén, Anna Bergman, Mark R. Farmery, Bengt Winblad, Urban Lendahl, Gunnar von Heijne, Jan Näslund	2005	149
9	Aph‐1 interacts at the cell surface with proteins in the active γ‐secretase complex and membrane‐tethered Notch Journal of Neurochemistry ·Emil M. Hansson, Kia Strömberg, Linda L Lang, Gang Yu, Jan Näslund, Johan Lundkvist, Urban Lendahl	2005	20
10	The Extreme C Terminus of Presenilin 1 Is Essential for γ-Secretase Complex Assembly and Activity Journal of Biological Chemistry ·Anna Bergman, Hanna Laudon, Bengt Winblad, Johan Lundkvist, Jan Näslund	2004	40
11	Characterization of long‐term mouse brain aggregating cultures: Evidence for maintenance of neural precursor cells The Journal of Comparative Neurology ·Caroline Berglund, Johan Aarum, Samantha L. Budd Haeberlein, Jens Randel Nyengaard, Tomas Hökfelt, Kristian Sandberg, Jan Näslund, Mats A. A. Persson	2004	17
12	Amyloid β Pathology in Alzheimer’s Disease and Schizophrenia American Journal of Psychiatry ·Dorota Religa, Hanna Laudon, Maria Styczyńska, Bengt Winblad, Jan Näslund, Vahram Haroutunian	2003	35
13	A Sensitive and Quantitative Assay for Measuring Cleavage of Presenilin Substrates Journal of Biological Chemistry ·Helena Karlström, Anna Bergman, Urban Lendahl, Jan Näslund, Johan Lundkvist	2002	86
14	The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Aβ protofibril formation Nature Neuroscience ·Camilla Nilsberth, Anita Westlind‐Danielsson, Christopher B. Eckman, Margaret M. Condron, Karin Axelman, Charlotte Forsell, Charlotte Stenh, Johan Luthman, David B. Teplow, Steven G. Younkin, Jan Näslund, Lars Lannfelt Hit paper breakdown →	2001	943
15	Intraneuronal Aβ42 Accumulation in Human Brain American Journal Of Pathology ·Gunnar K. Gouras, Julia Tsai, Jan Näslund, Bruno Vincent, Mark Edgar, Frédéric Checler, Jeffrey P. Greenfield, Vahram Haroutunian, Joseph D. Buxbaum, Huaxi Xu, Paul Greengard, Norman Relkin Hit paper breakdown →	2000	833
16	Correlation Between Elevated Levels of Amyloid β-Peptide in the Brain and Cognitive Decline JAMA ·Jan Näslund Hit paper breakdown →	2000	1042
17	Amyloid fibril formation by pulmonary surfactant protein C FEBS Letters ·Magnus Gustafsson, Johan Thyberg, Jan Näslund, Erik Eliasson, Jan Johansson	1999	95
18	Controlling Amyloid β-Peptide Fibril Formation with Protease-stable Ligands Journal of Biological Chemistry ·Lars O. Tjernberg, Christina Lilliehöök, David J.E. Callaway, Jan Näslund, Solveig Hahne, Johan Thyberg, Lars Terenius, Christer Nordstedt	1997	201
19	Generation of Alzheimer Amyloid β Peptide through Nonspecific Proteolysis Journal of Biological Chemistry ·Lars O. Tjernberg, Jan Näslund, Johan Thyberg, Sam Gandy, Lars Terenius, Christer Nordstedt	1997	25
20	Characterization of stable complexes involving apolipoprotein E and the amyloid β peptide in Alzheimer's disease brain Neuron ·Jan Näslund, Johan Thyberg, Lars O. Tjernberg, Christer Wernstedt, Anders R. Karlström, Nenad Bogdanović, Sam Gandy, Lars Lannfelt, Lars Terenius, Christer Nordstedt	1995	154

About Jan Näslund

Jan Näslund is a scholar working on Physiology, Pharmacology, Biomaterials, Molecular Biology and Computational Theory and Mathematics, having authored 51 papers that have together received 7.0k indexed citations. Recurring topics across this work include Alzheimer's disease research and treatments (46 papers), Prion Diseases and Protein Misfolding (12 papers), Cholinesterase and Neurodegenerative Diseases (9 papers), Computational Drug Discovery Methods (7 papers), Supramolecular Self-Assembly in Materials (6 papers), Amyloidosis: Diagnosis, Treatment, Outcomes (5 papers), Cellular transport and secretion (4 papers) and Dementia and Cognitive Impairment Research (4 papers). The work is most often cited by research in Physiology (5.4k citations), Biological Psychiatry (242 citations), Neurology (680 citations), Pharmacology (1.4k citations) and Computational Theory and Mathematics (1.0k citations). Jan Näslund has collaborated with scholars based in Sweden, United States and Japan. Frequent co-authors include Lars O. Tjernberg, Christer Nordstedt, Lars Terenius, Johan Thyberg, Bengt Winblad, Lars Lannfelt, Anders R. Karlström, Paul Greengard, Jan Johansson and Joseph D. Buxbaum. Their work appears in journals such as Journal of Biological Chemistry, Journal of Neurochemistry, Proceedings of the National Academy of Sciences, FEBS Letters and Neurobiology of Aging.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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