Sydney Brenner

59.8k total citations · 38 hit papers
305 papers, 45.1k citations indexed

About

Sydney Brenner is a scholar working on Molecular Biology, Genetics and Ecology. According to data from OpenAlex, Sydney Brenner has authored 305 papers receiving a total of 45.1k indexed citations (citations by other indexed papers that have themselves been cited), including 189 papers in Molecular Biology, 72 papers in Genetics and 43 papers in Ecology. Recurrent topics in Sydney Brenner's work include RNA and protein synthesis mechanisms (46 papers), Bacteriophages and microbial interactions (36 papers) and Genetics, Aging, and Longevity in Model Organisms (33 papers). Sydney Brenner is often cited by papers focused on RNA and protein synthesis mechanisms (46 papers), Bacteriophages and microbial interactions (36 papers) and Genetics, Aging, and Longevity in Model Organisms (33 papers). Sydney Brenner collaborates with scholars based in United Kingdom, United States and Singapore. Sydney Brenner's co-authors include J. Nichol Thomson, Eileen Southgate, JG White, Byrappa Venkatesh, R.W. Horne, F Jacob, John Sulston, Jonathan Hodgkin, Jonathan Karn and Richard A. Lerner and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Sydney Brenner

300 papers receiving 43.1k citations

Hit Papers

THE GENETICS OF CAENORHABDITIS ELEGANS 1959 2026 1981 2003 1974 1986 1959 1963 1985 4.0k 8.0k 12.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. THE GENETICS OF CAENORHABDITIS ELEGANS
    1974 12.8k citations Sydney Brenner profile →
  2. The structure of the nervous system of the nematode Caenorhabditis elegans
    1986 4.1k citations Sydney Brenner et al. profile →
  3. A negative staining method for high resolution electron microscopy of viruses
    1959 1.2k citations Sydney Brenner et al. profile →
  4. On the Regulation of DNA Replication in Bacteria
    1963 1.1k citations Sydney Brenner et al. profile →
  5. The neural circuit for touch sensitivity in Caenorhabditis elegans
    1985 821 citations Sydney Brenner et al. profile →
  6. SCOP: a Structural Classification of Proteins database
    1997 762 citations Sydney Brenner et al. profile →
  7. Encoded combinatorial chemistry.
    1992 750 citations Sydney Brenner et al. Proceedings of the National Academy of Sciences profile →
  8. An Unstable Intermediate Carrying Information from Genes to Ribosomes for Protein Synthesis
    1961 698 citations Sydney Brenner et al. Nature profile →
  9. NONDISJUNCTION MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS
    1979 655 citations Sydney Brenner et al. profile →
  10. Electron microscopical reconstruction of the anterior sensory anatomy of the nematode caenorhabditis elegans
    1975 617 citations Sydney Brenner et al. profile →
  11. THE DNA OF CAENORHABDITIS ELEGANS
    1974 506 citations Sydney Brenner et al. profile →
  12. Toward a physical map of the genome of the nematode Caenorhabditis elegans
    1986 503 citations Sydney Brenner et al. Proceedings of the National Academy of Sciences profile →
  13. The structure of the ventral nerve cord of Caenorhabditis elegans
    1976 481 citations Sydney Brenner et al. profile →
  14. Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome
    1993 479 citations Sydney Brenner, Greg Elgar et al. Nature profile →
  15. Sequence diversity among related genes for recognition of specific targets in DNA molecules
    1983 436 citations Jill Gough, Noreen E. Murray et al. Journal of Molecular Biology profile →
  16. A Trans-Species Missense SNP in Amhr2 Is Associated with Sex Determination in the Tiger Pufferfish, Takifugu rubripes (Fugu)
    2012 432 citations Sydney Brenner, Byrappa Venkatesh et al. profile →
  17. Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
    1995 432 citations Sydney Brenner et al. profile →
  18. A GENETIC LOCUS FOR THE REGULATION OF RIBONUCLEIC ACID SYNTHESIS
    1961 408 citations Sydney Brenner et al. Proceedings of the National Academy of Sciences profile →
  19. Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle
    1989 405 citations Sydney Brenner et al. Nature profile →
  20. The octopus genome and the evolution of cephalopod neural and morphological novelties
    2015 404 citations Oleg Simakov, Sydney Brenner et al. Nature profile →
  21. Dopaminergic neurons in the nematode Caenorhabditis elegans
    1975 387 citations Sydney Brenner et al. profile →
  22. A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1
    1994 381 citations Sydney Brenner et al. Nature profile →
  23. Novel bacteriophage lambda cloning vector.
    1980 357 citations Sydney Brenner et al. Proceedings of the National Academy of Sciences profile →
  24. Amber Suppression: a Nucleotide Change in the Anticodon of a Tyrosine Transfer RNA
    1968 357 citations Sydney Brenner et al. Nature profile →
  25. A uniform genetic nomenclature for the nematode Caenorhabditis elegans
    1979 343 citations Sydney Brenner et al. profile →
  26. Genetic Code: The ‘Nonsense’ Triplets for Chain Termination and their Suppression
    1965 279 citations Sydney Brenner et al. Nature profile →
  27. Origin of Antibody Variation
    1966 252 citations Sydney Brenner et al. Nature profile →
  28. Mutants with altered muscle structure in Caenorhabditis elegans
    1980 241 citations Sydney Brenner et al. profile →
  29. Nonsense mutants and polarity in the Lac operon of Escherichia coli
    1965 233 citations Sydney Brenner et al. Journal of Molecular Biology profile →
  30. A speculation on the origin of protein synthesis
    1976 231 citations Sydney Brenner et al. profile →
  31. MUTATIONS CAUSING TRANSFORMATION OF SEXUAL PHENOTYPE IN THE NEMATODE CAENORHABDITIS ELEGANS
    1977 212 citations Sydney Brenner et al. profile →
  32. Ochre mutants, a new class of suppressible nonsense mutants
    1965 203 citations Sydney Brenner et al. Journal of Molecular Biology profile →
  33. A mutant affecting the heavy chain of myosin in Caenorhabditis elegans
    1974 202 citations Sydney Brenner et al. Journal of Molecular Biology profile →
  34. Duplicate genes for tyrosine transfer RNA in Escherichia coli
    1970 201 citations Sydney Brenner et al. Journal of Molecular Biology profile →
  35. The theory of mutagenesis
    1961 192 citations Sydney Brenner et al. Journal of Molecular Biology profile →
  36. Structural components of bacteriophage
    1959 186 citations Sydney Brenner et al. Journal of Molecular Biology profile →
  37. THE GENETICS OF BEHAVIOUR
    1973 175 citations Sydney Brenner profile →
  38. The icosahedral form of an adenovirus
    1959 168 citations Sydney Brenner et al. Journal of Molecular Biology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Sydney Brenner United Kingdom 88 25.3k 17.0k 8.0k 6.3k 4.5k 305 45.1k
H. Robert Horvitz United States 107 31.7k 1.3× 21.2k 1.2× 3.0k 0.4× 8.3k 1.3× 4.5k 1.0× 252 51.6k
Linda Partridge United Kingdom 115 20.7k 0.8× 17.2k 1.0× 10.8k 1.4× 5.0k 0.8× 9.4k 2.1× 575 63.5k
Gary Ruvkun United States 93 26.8k 1.1× 17.5k 1.0× 2.8k 0.3× 6.1k 1.0× 2.0k 0.4× 218 42.8k
Paul W. Sternberg United States 97 13.9k 0.5× 12.6k 0.7× 2.6k 0.3× 5.7k 0.9× 2.3k 0.5× 579 33.1k
Cornelia I. Bargmann United States 98 11.4k 0.4× 16.7k 1.0× 3.4k 0.4× 10.4k 1.7× 11.2k 2.5× 181 34.4k
Richard I. Morimoto United States 109 33.3k 1.3× 8.0k 0.5× 1.8k 0.2× 1.2k 0.2× 3.6k 0.8× 285 43.8k
Andrew Fire United States 76 28.6k 1.1× 9.1k 0.5× 4.3k 0.5× 1.6k 0.2× 1.1k 0.2× 177 36.6k
Paolo Sassone‐Corsi France 118 23.4k 0.9× 4.1k 0.2× 9.1k 1.1× 14.5k 2.3× 5.3k 1.2× 433 48.2k
Seymour Benzer United States 73 10.2k 0.4× 3.4k 0.2× 3.7k 0.5× 2.7k 0.4× 8.8k 2.0× 119 20.8k
Martin Chalfie United States 57 10.1k 0.4× 6.8k 0.4× 1.5k 0.2× 3.3k 0.5× 3.1k 0.7× 119 17.6k

Countries citing papers authored by Sydney Brenner

Since Specialization
Citations

This map shows the geographic impact of Sydney Brenner's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sydney Brenner with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sydney Brenner more than expected).

Fields of papers citing papers by Sydney Brenner

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sydney Brenner. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sydney Brenner. The network helps show where Sydney Brenner may publish in the future.

Co-authorship network of co-authors of Sydney Brenner

This figure shows the co-authorship network connecting the top 25 collaborators of Sydney Brenner. A scholar is included among the top collaborators of Sydney Brenner based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sydney Brenner. Sydney Brenner is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Marlétaz, Ferdinand, Nataliya Timoshevskaya, Vladimir A. Timoshevskiy, et al.. (2024). The hagfish genome and the evolution of vertebrates. Nature. 627(8005). 811–820. 35 indexed citations
2.
Rana, Kesha, Kristi Milley, Helen E. MacLean, et al.. (2013). Expression of Wnt signaling skeletal development genes in the cartilaginous fish, elephant shark (Callorhinchus milii). General and Comparative Endocrinology. 193. 1–9. 3 indexed citations
3.
Lane, David P., Arumugam Madhumalar, Alison Lee, et al.. (2011). Conservation of all three p53 family members and Mdm2 and Mdm4 in the cartilaginous fish. Cell Cycle. 10(24). 4272–4279. 29 indexed citations
4.
Ravi, Vydianathan, Kevin C. L. Lam, Boon-Hui Tay, et al.. (2009). Elephant shark ( Callorhinchus milii ) provides insights into the evolution of Hox gene clusters in gnathostomes. Proceedings of the National Academy of Sciences. 106(38). 16327–16332. 64 indexed citations
5.
Venkatesh, Byrappa, Ewen F. Kirkness, Yong‐Hwee Eddie Loh, et al.. (2006). Ancient Noncoding Elements Conserved in the Human Genome. Science. 314(5807). 1892–1892. 95 indexed citations
6.
Lim, Siew Pheng, Hui Meng Soo, Yin Tan, et al.. (2002). Inducible System in Human Hepatoma Cell Lines for Hepatitis C Virus Production. Virology. 303(1). 79–99. 16 indexed citations
7.
Brenner, Sydney, et al.. (2001). A life in science. 4 indexed citations
8.
Brenner, Sydney. (2001). After the (draft) sequence.. Genome Biology. 2(5). comment1006.1–comment1006.1. 1 indexed citations
9.
Brenner, Sydney. (1999). The march of thyme. Current Biology. 9(8). R267–R267.
10.
Elgar, Greg, Melody S. Clark, Stephen Meek, et al.. (1999). Generation and Analysis of 25 Mb of Genomic DNA from the Pufferfish Fugu rubripes by Sequence Scanning. Genome Research. 9(10). 960–971. 70 indexed citations
11.
Brenner, Sydney. (1998). Titles. Current Biology. 8(1). R1–R1. 2 indexed citations
12.
13.
Brenner, Sydney. (1996). Loose ends. Current Biology. 6(1). 98–98. 3 indexed citations
14.
Brenner, Sydney. (1995). Molecular biology by numbers ..... three. Current Biology. 5(12). 1464–1464. 1 indexed citations
15.
Brenner, Sydney. (1995). Loose ends. Current Biology. 5(9). 1080–1080. 1 indexed citations
16.
Maruyama, Ichiro & Sydney Brenner. (1991). Caenorhabditis elegansのunc‐13遺伝子がコードするホルボールエステル/ジアシルグリセロール結合蛋白質. Proc Natl Acad Sci USA. 88(13). 5729–5733. 91 indexed citations
17.
Brenner, Sydney. (1989). Molecular biology : a selection of papers. Academic Press eBooks. 2 indexed citations
18.
Brenner, Sydney. (1984). Confessions of a biologist. Nature. 308(5962). 794–794.
19.
Gough, Jill, Noreen E. Murray, & Sydney Brenner. (1983). Sequence diversity among related genes for recognition of specific targets in DNA molecules. Journal of Molecular Biology. 166(1). 1–19. 436 indexed citations breakdown →
20.
Brenner, Sydney, et al.. (1981). Theories of biological pattern formation : a Royal Society discussion held on 25 and 26 March 1981. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

You can learn more about the impact of Sydney Brenner by visiting their Pantheon page.

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