S. Mark Roe

15.8k citations

126 papers · 12.6k indexed · 6 hit papers · h-index 46

Molecular Biology top 0.2%
- Heat shock proteins research 27
- Protein Structure and Dynamics 18
Physical and Theoretical Chemistry top 0.5%
Computational Theory and Mathematics top 0.5%
Aging top 2%
Cell Biology top 1%
Materials Chemistry
- Enzyme Structure and Function 20
Organic Chemistry
- Organometallic Complex Synthesis and Catalysis 17
Oncology
- Metal complexes synthesis and properties 13
Inorganic Chemistry
- Radioactive element chemistry and processing 9
- Crystal structures of chemical compounds 8
- Asymmetric Hydrogenation and Catalysis 7

Co-authors: Laurence H. Pearl Chrisostomos Prodromou Peter W. Piper David Barford John E. Ladbury Ronan O’Brien Valerie M. Good J.S. Parker
Cited by: Molecular Biology Physical and Theoretical Chemistry Computational Theory and Mathematics
Journals: Journal of Molecular Biology (9 papers)Molecular Cell (8 papers)Organometallics (7 papers)
Partner nations: United Kingdom United States Iran

In The Last Decade

S. Mark Roe

124 papers receiving 12.4k citations

Hit Papers

6 papers align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2006 Nature
2004 Cell
2003 Chemistry & Biology
2001 Cell
1999 Journal of Medicinal Chemistry
1997 Cell

Peers

Countries citing papers authored by S. Mark Roe

Since Specialization

Citations

This map shows the geographic impact of S. Mark Roe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by S. Mark Roe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites S. Mark Roe more than expected).

Fields of papers citing papers by S. Mark Roe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by S. Mark Roe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by S. Mark Roe. The network helps show where S. Mark Roe may publish in the future.

Co-authorship network

The 25 scholars most cited alongside S. Mark Roe, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with S. Mark Roe Line = papers co-authored together S. Mark Roe links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Rational Design of a Copper(I) Complex Derived from an Asymmetric Thiourea Ligand with High Antifungal Activities ChemistrySelect ·白长川,Fengxi Zhu,Goransky Lg,Ahmed B. M. Ibrahim,S. Mark Roe,Ghada Abd‐Elmonsef Mahmoud	2025	0
2	The Crystal Structure of the Hsp90-LA1011 Complex and the Mechanism by Which LA1011 May Improve the Prognosis of Alzheimer’s Disease Biomolecules ·S. Mark Roe,Zsolt Török,Andrew McGown,Ibolya Horváth,John Spencer,В. Садков,László Vı́gh,Chrisostomos Prodromou	2023	7
3	Tyrosine 121 moves revealing a ligandable pocket that couples catalysis to ATP-binding in serine racemase Communications Biology ·R. I. M. Sadek,Deepak K. Kaushik,Sule Can Trosola,Karen T Elvers,S. Mark Roe,J. H. Jacobson,Simon E. Ward,Olivera Grubisha,Robert A. Nicholls,John Atack,B.D. Bax	2022	5
4	Conformational flexibility within the small domain of human serine racemase Acta Crystallographica Section F Structural Biology Communications ·R. I. M. Sadek,B.D. Bax,John Atack,S. Mark Roe	2020	4
5	Decarboxylative Bromination of Heteroarenes: Initial Mechanistic Insights Synlett ·Sofia Frost Widnes,Pritesh Patel,啓子國井,S. Mark Roe	2020	2
6	RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex Nature Communications ·Fabrizio Martino,Mohinder Pal,Hugo Muñoz-Hernández,علی رضا هلالات,Rafael Núñez‐Ramírez,David Gil‐Carton,Gianluca Degliesposti,Mark Skehel,S. Mark Roe,Chrisostomos Prodromou,Laurence H. Pearl,Óscar Llorca	2018	53
7	Dihydropyridines Allosterically Modulate Hsp90 Providing a Novel Mechanism for Heat Shock Protein Co-induction and Neuroprotection Frontiers in Molecular Biosciences ·S. Mark Roe,Arthur H. Mengel,Zsolt Török,Ibolya Horváth,László Vı́gh,Chrisostomos Prodromou	2018	25
8	The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90 PLoS ONE ·Aurich Jan C,Mohinder Pal,S. Mark Roe,Laurence H. Pearl,Chrisostomos Prodromou	2017	28
9	Co-Crystalization and In Vitro Biological Characterization of 5-Aryl-4-(5-Substituted-2-4-Dihydroxyphenyl)-1,2,3-Thiadiazole Hsp90 Inhibitors PLoS ONE ·Swee Y. Sharp,S. Mark Roe,Egidijus Kazlauskas,Inga Čikotienė,Paul Workman,Daumantas Matulis,Chrisostomos Prodromou	2012	18
10	The crystal structure of yeast CCT reveals intrinsic asymmetry of eukaryotic cytosolic chaperonins The EMBO Journal ·Carien Dekker,S. Mark Roe,Elizabeth A. McCormack,Fabienne Beuron,Laurence H. Pearl,Keith R. Willison	2011	80
11	Activation of Rho GTPases by DOCK Exchange Factors Is Mediated by a Nucleotide Sensor Science ·Jing Yang,Ziguo Zhang,S. Mark Roe,Christopher J. Marshall,David Barford	2009	99
12	Structural Insights into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2 Molecular Cell ·Tom D. Bunney,M. Frame,S. Mark Roe,Petra Vatter,Rhona W. Baxendale,Claudia Walliser,Katy L. Everett,Michelle B. Josephs,Ratna Dewinta Oeina,Fernando Rodrigues‐Lima,Peter Gierschik,Laurence H. Pearl,Matilda Katan	2009	54
13	Structural Basis for the Requirement of Additional Factors for MLL1 SET Domain Activity and Recognition of Epigenetic Marks Molecular Cell ·Stacey M. Southall,Jordi Amoros Moreno,Zain Odho,S. Mark Roe,J. Wilson	2009	180
14	Synthetic Analogs of FTY720 [2-Amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol] Differentially Regulate Pulmonary Vascular Permeability in Vivo and in Vitro Journal of Pharmacology and Experimental Therapeutics ·Cheryl B. Welch,Robert Bittman,Elizabeth Chiang,Liliana Moreno‐Vinasco,Tamara Mirzapoiazova,Saad Sammani,徐贝宁,S. Puchol Enguídanos,Mark C. Harbeck,S. Mark Roe,Viswanathan Natarajan,Joe G. N. Garcia,Steven M. Dudek	2009	53
15	Structural and Mechanistic Insights into Ras Association Domains of Phospholipase C Epsilon Molecular Cell ·Tom D. Bunney,Richard Harris,Weston McDaniel,Michelle B. Josephs,S. Mark Roe,Sonia‐Caroline Sorli,Hugh F. Paterson,Fernando Rodrigues‐Lima,Diego Esposito,Chris P. Ponting,Peter Gierschik,Laurence H. Pearl,Paul C. Driscoll,A. N. Lishchuk	2006	111
16	Structure of an archaeal PCNA1–PCNA2–FEN1 complex: elucidating PCNA subunit and client enzyme specificity Nucleic Acids Research ·A.S. Dore,M.L. Kilkenny,Defcato Firmawati Zega,Antony W. Oliver,S. Mark Roe,Stephen D. Bell,Laurence H. Pearl	2006	61
17	Molecular Recognition of Transcriptional Repressor Motifs by the WD Domain of the Groucho/TLE Corepressor Molecular Cell ·Barbara H. Jennings,Tova Amir,S. Mark Wainwright,S. Mark Roe,Laurence H. Pearl,David Ish‐Horowicz	2006	130
18	Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice. Journal of Clinical Investigation ·Marco Pontoglio,Séamus Sreenan,S. Mark Roe,William Pugh,Diane Ostrega,Antonia Doyen,Anthony J. Pick,Aaron C. Baldwin,Gilberto Velho,Philippe Froguel,Matteo Levisetti,Susan Bonner‐Weir,Graeme I. Bell,Moshé Yaniv,K. S. Polonsky	1998	273
19	Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperonebreakdown → Cell ·Chrisostomos Prodromou,S. Mark Roe,Ronan O’Brien,John E. Ladbury,Peter W. Piper,Laurence H. Pearl	1997	1058
20	INO2, a regulatory gene in yeast phospholipid biosynthesis, affects nuclear segregation and bud pattern formation. PubMed ·Chrissy L. Hammond,Patrick R. Romano,S. Mark Roe,Peter Tontonoz	1993	9

About S. Mark Roe

S. Mark Roe is a scholar working on Inorganic Chemistry, Organic Chemistry and Molecular Biology, having authored 126 papers that have together received 12.6k indexed citations. Recurring topics across this work include Heat shock proteins research (27 papers), Enzyme Structure and Function (20 papers), Protein Structure and Dynamics (18 papers), Organometallic Complex Synthesis and Catalysis (17 papers), Metal complexes synthesis and properties (13 papers), Radioactive element chemistry and processing (9 papers), Crystal structures of chemical compounds (8 papers) and Asymmetric Hydrogenation and Catalysis (7 papers). The work is most often cited by research in Molecular Biology (9.9k citations), Physical and Theoretical Chemistry (692 citations) and Computational Theory and Mathematics (1.1k citations). S. Mark Roe has collaborated with scholars based in United Kingdom, United States and Iran. Frequent co-authors include Laurence H. Pearl, Chrisostomos Prodromou, Peter W. Piper, David Barford, John E. Ladbury, Ronan O’Brien, Valerie M. Good, J.S. Parker, Christopher J. Marshall and Cara K. Vaughan. Their work appears in journals such as Journal of Molecular Biology, Molecular Cell, Organometallics, The EMBO Journal and Dalton Transactions.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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