Simon E. Ward

2.4k citations

67 papers · 1.6k indexed · h-index 22

Impact in

Sensory Systems top 5%
- Hearing, Cochlea, Tinnitus, Genetics
Organic Chemistry top 5%

Papers in ⓘ

Sensory Systems 5
- Hearing, Cochlea, Tinnitus, Genetics 5
Cellular and Molecular Neuroscience 14
- Neuroscience and Neuropharmacology Research 8
- Neurotransmitter Receptor Influence on Behavior 6

Co-authors: Laurence H. Pearl (5 shared papers)Frances M. G. Pearl (3 shared papers)Amanda C. Schierz (1 shared paper)Bissan Al‐Lazikani (1 shared paper)Paul Beswick (6 shared papers)Mark H Harries (6 shared papers)Vincent Rodeschini (3 shared papers)Nigel S. Simpkins (3 shared papers)
Journals: Journal of Medicinal Chemistry (9 papers)Bioorganic & Medicinal Chemistry Letters (6 papers)European Journal of Medicinal Chemistry (3 papers)Chemical Communications (2 papers)Organic & Biomolecular Chemistry (2 papers)
Partner nations: United Kingdom United States Brazil

In The Last Decade

Simon E. Ward

66 papers receiving 1.6k citations

Peers

Countries citing papers authored by Simon E. Ward

Since Specialization

Citations

This map shows the geographic impact of Simon E. Ward's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon E. Ward with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon E. Ward more than expected).

Fields of papers citing papers by Simon E. Ward

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon E. Ward. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon E. Ward. The network helps show where Simon E. Ward may publish in the future.

Co-authors

The 25 scholars most cited alongside Simon E. Ward, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Simon E. Ward Line = papers co-authored together Simon E. Ward links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 67 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Therapeutic opportunities within the DNA damage response Nature reviews. Cancer ·Laurence H. Pearl, Amanda C. Schierz, Simon E. Ward, Bissan Al‐Lazikani, Frances M. G. Pearl	2015	391
2	Synthesis of Polyprenylated Acylphloroglucinols Using Bridgehead Lithiation: The Total Synthesis of Racemic Clusianone and a Formal Synthesis of Racemic Garsubellin A The Journal of Organic Chemistry ·Nadia M. Ahmad, Vincent Rodeschini, Nigel S. Simpkins, Simon E. Ward, Alexander J. Blake	2007	86
3	What does the aromatic ring number mean for drug design? Expert Opinion on Drug Discovery ·Simon E. Ward, Paul Beswick	2014	65
4	Clinical and Cellular Roles for TDP1 and TOP1 in Modulating Colorectal Cancer Response to Irinotecan Molecular Cancer Therapeutics ·Cornelia Meisenberg, Duncan C. Gilbert, Anthony J. Chalmers, Vikki Haley, Simon Gollins, Simon E. Ward, Sherif F. El‐Khamisy	2014	63
5	Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators Journal of Medicinal Chemistry ·Simon E. Ward, Mark H Harries, Laura Aldegheri, Nigel Austin, Stuart P. Ballantine, Elisa Ballini, Daniel M. Bradley, B.D. Bax, Brian Clarke, A. I. Harris, Stephen A. Harrison, Rosemary A. Melarange, Claudette Mookherjee, J. Mosley, Gianni Dal Negro, Beatrice Oliosi, Kathrine J. Smith, Kevin M. Thewlis, P.M. Woollard, Shahnaz P. Yusaf	2010	57
6	Selective Cleavage of Benzyl Ethers Synlett ·Miles Congreve, Edwin C. Davison, Mary Ann M. Fuhry, Andrew B. Holmes, Andrew N. Payne, R. Anthony Robinson, Simon E. Ward	1993	55
7	Challenges for and current status of research into positive modulators of AMPA receptors British Journal of Pharmacology ·Simon E. Ward, B.D. Bax, Mark H Harries	2010	54
8	Subtype Selective γ-Aminobutyric Acid Type A Receptor (GABA_AR) Modulators Acting at the Benzodiazepine Binding Site: An Update Journal of Medicinal Chemistry ·Samuele Maramai, Mohamed Benchekroun, Simon E. Ward, John Atack	2019	47
9	Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan Nucleic Acids Research ·Cornelia Meisenberg, Mohamed E. Ashour, Lamia El-Shafie, Chunyan Liao, Adam Hodgson, Alice Elizabeth Pilborough, Syed Ali Khurram, Jessica A. Downs, Simon E. Ward, Sherif F. El‐Khamisy	2016	46
10	Liver Immune Microenvironment and Metastasis from Colorectal Cancer-Pathogenesis and Therapeutic Perspectives Cancers ·Xuezhen Zeng, Simon E. Ward, Jingying Zhou, Alfred S.L. Cheng	2021	45
11	d-Tubocurarine and Berbamine: Alkaloids That Are Permeant Blockers of the Hair Cell's Mechano-Electrical Transducer Channel and Protect from Aminoglycoside Toxicity Frontiers in Cellular Neuroscience ·Nerissa K. Kirkwood, Molly O’Reilly, Marco Derudas, Emma Kenyon, Rosemary Huckvale, Sietse M. van Netten, Simon E. Ward, Guy P. Richardson, Corné J. Kros	2017	41
12	CCRK is a novel signalling hub exploitable in cancer immunotherapy Pharmacology & Therapeutics ·Myth T.S. Mok, Jingying Zhou, Wenshu Tang, Xuezhen Zeng, Antony W. Oliver, Simon E. Ward, Alfred S.L. Cheng	2018	38
13	Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2 Biochemical Journal ·P. Hornyak, Trevor Askwith, Sarah Walker, Emilia Komulainen, Michael Paradowski, Lewis E. Pennicott, Edward Bartlett, Nigel C. Brissett, Ali Raoof, Mandy Watson, Allan M. Jordan, Donald Ogilvie, Simon E. Ward, John Atack, Laurence H. Pearl, Keith W. Caldecott, Antony W. Oliver	2016	32
14	A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct Oncotarget ·Cory A. Ocasio, Mohan B. Rajasekaran, Sarah Walker, Darren Le Grand, John Spencer, Frances M. G. Pearl, Simon E. Ward, Velibor Savic, Laurence H. Pearl, Helfrid Hochegger, Antony W. Oliver	2016	30
15	Synthetic studies towards garsubellin A: synthesis of model systems and potential mimics by regioselective lithiation of bicyclo[3.3.1]nonane-2,4,9-trione derivatives from catechinic acid Organic & Biomolecular Chemistry ·Nadia M. Ahmad, Vincent Rodeschini, Nigel S. Simpkins, Simon E. Ward, Claire Wilson	2007	27
16	Stereoselective γ-lactam synthesis via palladium-catalysed intramolecular allylation Chemical Communications ·Donald C. Craig, Christopher J. T. Hyland, Simon E. Ward	2005	26
17	Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death JCI Insight ·Emma Kenyon, Nerissa K. Kirkwood, Siân R. Kitcher, Molly O’Reilly, Marco Derudas, Daire Cantillon, Richard J. Goodyear, Abigail Secker, Sarah Baxendale, James C. Bull, Simon J. Waddell, Tanya T. Whitfield, Simon E. Ward, Corné J. Kros, Guy P. Richardson	2017	25
18	Evaluation of the anti-malarial activity and cytotoxicity of 2,4-diamino-pyrimidine-based kinase inhibitors European Journal of Medicinal Chemistry ·Oraphan Phuangsawai, Paul Beswick, Siriluk Ratanabunyong, Lueacha Tabtimmai, Praphasri Suphakun, Phongphat Obounchoey, Pimonwan Srisook, Natharinee Horata, Irina Chuckowree, Supa Hannongbua, Simon E. Ward, Kiattawee Choowongkomon, M. Paul Gleeson	2016	24
19	AMPA Receptor Positive Allosteric Modulators: Potential for the Treatment of Neuropsychiatric and Neurological Disorders Current Topics in Medicinal Chemistry ·Tristan Reuillon, Simon E. Ward, Paul Beswick	2016	24
20	AMPA Receptor-Positive Allosteric Modulators for the Treatment of Schizophrenia: An Overview of Recent Patent Applications Future Medicinal Chemistry ·Simon E. Ward, Lewis E. Pennicott, Paul Beswick	2015	24

About Simon E. Ward

Simon E. Ward is a scholar working on Sensory Systems, Cellular and Molecular Neuroscience, Organic Chemistry, Molecular Biology and Microbiology, having authored 67 papers that have together received 1.6k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (9 papers), Neuroscience and Neuropharmacology Research (8 papers), Cancer therapeutics and mechanisms (7 papers), Neurotransmitter Receptor Influence on Behavior (6 papers), Pharmacological Receptor Mechanisms and Effects (5 papers), Hearing, Cochlea, Tinnitus, Genetics (5 papers), Cancer-related Molecular Pathways (4 papers) and Chemical synthesis and alkaloids (4 papers). The work is most often cited by research in Sensory Systems (80 citations), Organic Chemistry (421 citations), Molecular Biology (933 citations), Toxicology (46 citations) and Oncology (359 citations). Simon E. Ward has collaborated with scholars based in United Kingdom, United States and Brazil. Frequent co-authors include Laurence H. Pearl, Frances M. G. Pearl, Amanda C. Schierz, Bissan Al‐Lazikani, Paul Beswick, Mark H Harries, Vincent Rodeschini, Nigel S. Simpkins, B.D. Bax and John Atack. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, European Journal of Medicinal Chemistry, Chemical Communications and Organic & Biomolecular Chemistry.

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