David Barford

26.2k citations

158 papers · 20.4k indexed · 5 hit papers · h-index 73

Impact in

Molecular Biology top 0.1%
- Protein Tyrosine Phosphatases
- Ubiquitin and proteasome pathways
- Protein Kinase Regulation and GTPase Signaling
- Melanoma and MAPK Pathways
- RNA and protein synthesis mechanisms
Cell Biology top 0.1%
- Microtubule and mitosis dynamics

Papers in

Cell Biology 64
- Microtubule and mitosis dynamics 54
Structural Biology 5

Co-authors: Nicholas K. Tonks Andrew Flint S. Mark Roe L.N. JohnsonJing YangAnnette Salmeen Ziguo Zhang Amit Kumar Das
Journals: Nature (15 papers)Molecular Cell (13 papers)Journal of Biological Chemistry (11 papers)Journal of Molecular Biology (11 papers)Current Opinion in Structural Biology (8 papers)
Partner nations: United Kingdom United States Switzerland

In The Last Decade

David Barford

157 papers receiving 20.0k citations

Hit Papers

5 papers align trajectories log scale

Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF 2004 · 2.2k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2004 Cell
2003 Nature
1998 Annual Review of Biophysics and Biomolecular Structure
1997 Proceedings of the National Academy of Sciences
1994 Science

Peers

Countries citing papers authored by David Barford

Since Specialization

Citations

This map shows the geographic impact of David Barford's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Barford with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Barford more than expected).

Fields of papers citing papers by David Barford

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Barford. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Barford. The network helps show where David Barford may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David Barford, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David Barford Line = papers co-authored together David Barford links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome eLife ·Souhami Luis, Christoph Wielenberg, Christopher J. Stubbs, Marianne Schimpl, Thomas Tischer, Eileen McCall, Maria Zacharopoulou, Fernando Ferrer, David Barford, David R. Spring, Catherine Lindon, Christopher Phillips, Laura S. Itzhaki	2025	0
2	Cryo-EM structures of apo-APC/C and APC/CCDH1:EMI1 complexes provide insights into APC/C regulation Nature Communications ·Yurii M. Hupalo, Brusnitsyn A.I., Jing Yang, Ziguo Zhang, Leifu Chang, Stephen H. McLaughlin, G.W. Grime, Elspeth F. Garman, Andreas Boland, David Barford	2024	2
3	A comparative study of the cryo-EM structures of Saccharomyces cerevisiae and human anaphase-promoting complex/cyclosome (APC/C) eLife ·Ester Vázquez-Fernández, Jing Yang, Ziguo Zhang, Antonina Andreeva, Paul Emsley, David Barford	2024	1
4	A comparative study of the cryo-EM structures of Saccharomyces cerevisiae and human anaphase-promoting complex/cyclosome (APC/C) eLife ·Ester Vázquez-Fernández, Jing Yang, Ziguo Zhang, Antonina Andreeva, Paul Emsley, David Barford	2024	1
5	Conserved and divergent mechanisms of inner kinetochore assembly onto centromeric chromatin Current Opinion in Structural Biology ·Stanislau Yatskevich, David Barford, Kyle Muir	2023	16
6	Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration Nature Communications ·Viviane Tran, 兵庫医科大学核医学科, Amélie Robert, Inès Desanlis, Shengman Zhang, Sophie Ehresmann, Marie‐Pier Thibault, David Barford, Kodi S. Ravichandran, Мусихина Ольга Владимировна, Matthew J. Smith, Marie Kmita, Jean‐François Côté	2022	9
7	Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome Science ·Stanislau Yatskevich, Kyle Muir, Dom Bellini, Ziguo Zhang, Jing Yang, Thomas Tischer, Nancy Mbandi Mutange, Tom Dendooven, Stephen H. McLaughlin, David Barford	2022	72
8	Molecular architecture of the augmin complex Nature Communications ·C. Gabel, Zhuang Li, Asya Svirinovsky Arbeli, Ziguo Zhang, Jing Yang, Mark C. Hall, David Barford, Leifu Chang	2022	15
9	Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation Cell Reports ·Stanislau Yatskevich, Kamila Derková, Claudio Alfieri, Thomas Tischer, 원지은, Linda Clijsters, Jing Yang, Ziguo Zhang, Kaige Yan, Alfred C.O. Vertegaal, David Barford	2021	15
10	Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1 EMBO Reports ·Debbie Evans, C. Yu, Dom Bellini, Stephen H. McLaughlin, Christian M. Orr, Armin Wagner, Stefan M.V. Freund, David Barford	2021	25
11	The APC/C targets the Cep152–Cep63 complex at the centrosome to regulate mitotic spindle assembly Journal of Cell Science ·Thomas Tischer, Jing Yang, David Barford	2021	8
12	Structural basis of human separase regulation by securin and CDK1–cyclin B1 Nature ·Brusnitsyn A.I., ایرج همرنگ, Chloe M. Ghent, Tobias Raisch, Yashar Sadian, Simone Cavadini, Pramod M. Sabale, David Barford, Stefan Raunser, David O. Morgan, Andreas Boland	2021	59
13	Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP Proceedings of the National Academy of Sciences ·Katerina Naydenova, Kyle Muir, Long-Fei Wu, Ziguo Zhang, Francesca Coscia, M.J. Peet, Pablo Castro‐Hartmann, Qian Pu, Kasim Sader, Kyle C. Dent, Dari Kimanius, John D. Sutherland, Jan Löwe, David Barford, Christopher J. Russo	2021	142
14	Crystal structure of the Cenp-HIKHead-TW sub-module of the inner kinetochore CCAN complex Nucleic Acids Research ·Ziguo Zhang, Dom Bellini, David Barford	2020	13
15	A unique binding mode of Nek2A to the APC /C allows its ubiquitination during prometaphase EMBO Reports ·Claudio Alfieri, Thomas Tischer, David Barford	2020	19
16	Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C Nature Communications ·Suyang Zhang, Thomas Tischer, David Barford	2019	44
17	Architecture of the CBF3–centromere complex of the budding yeast kinetochore Nature Structural & Molecular Biology ·Kaige Yan, Ziguo Zhang, Jing Yang, Stephen H. McLaughlin, David Barford	2018	18
18	Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C) Open Biology ·Claudio Alfieri, Suyang Zhang, David Barford	2017	114
19	Activation of Rho GTPases by DOCK Exchange Factors Is Mediated by a Nucleotide Sensor Science ·Jing Yang, Ziguo Zhang, S. Mark Roe, Christopher J. Marshall, David Barford	2009	99
20	Electrostatic effects in the control of glycogen phosphorylase by phosphorylation Protein Science ·L.N. Johnson, David Barford	1994	25

About David Barford

David Barford is a scholar working on Cell Biology, Structural Biology, Molecular Biology, Aging and Immunology, having authored 158 papers that have together received 20.4k indexed citations. Recurring topics across this work include Microtubule and mitosis dynamics (54 papers), Ubiquitin and proteasome pathways (38 papers), Protein Tyrosine Phosphatases (28 papers), Enzyme Structure and Function (23 papers), Photosynthetic Processes and Mechanisms (17 papers), Galectins and Cancer Biology (17 papers), Glycosylation and Glycoproteins Research (16 papers) and Protein Kinase Regulation and GTPase Signaling (15 papers). The work is most often cited by research in Molecular Biology (17.1k citations), Cell Biology (3.8k citations), Immunology (3.4k citations), Toxicology (410 citations) and Oncology (3.1k citations). David Barford has collaborated with scholars based in United Kingdom, United States and Switzerland. Frequent co-authors include Nicholas K. Tonks, Andrew Flint, S. Mark Roe, L.N. Johnson, Jing Yang, Annette Salmeen, Ziguo Zhang, Amit Kumar Das, J.S. Parker and Valerie M. Good. Their work appears in journals such as Nature, Molecular Cell, Journal of Biological Chemistry, Journal of Molecular Biology and Current Opinion in Structural Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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