John E. Ladbury

18.5k total citations · 4 hit papers
175 papers, 12.3k citations indexed

About

John E. Ladbury is a scholar working on Molecular Biology, Physical and Theoretical Chemistry and Genetics. According to data from OpenAlex, John E. Ladbury has authored 175 papers receiving a total of 12.3k indexed citations (citations by other indexed papers that have themselves been cited), including 139 papers in Molecular Biology, 36 papers in Physical and Theoretical Chemistry and 22 papers in Genetics. Recurrent topics in John E. Ladbury's work include thermodynamics and calorimetric analyses (34 papers), Protein Structure and Dynamics (32 papers) and RNA and protein synthesis mechanisms (19 papers). John E. Ladbury is often cited by papers focused on thermodynamics and calorimetric analyses (34 papers), Protein Structure and Dynamics (32 papers) and RNA and protein synthesis mechanisms (19 papers). John E. Ladbury collaborates with scholars based in United Kingdom, United States and Australia. John E. Ladbury's co-authors include Ronan O’Brien, S. Mark Roe, Chrisostomos Prodromou, Laurence H. Pearl, Peter W. Piper, Mark A. Williams, Stefan T. Arold, Babur Z. Chowdhry, Ihtshamul Haq and Mark A. Lemmon and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

John E. Ladbury

173 papers receiving 12.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperone

1997 1.1k citations Chrisostomos Prodromou, S. Mark Roe et al. Cell profile →
Structural Basis for Inhibition of the Hsp90 Molecular Chaperone by the Antitumor Antibiotics Radicicol and Geldanamycin

1999 823 citations S. Mark Roe, Chrisostomos Prodromou et al. profile →
Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation

1994 555 citations John E. Ladbury et al. Cell profile →
Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions

2012 491 citations Fernando A. Melo, John E. Ladbury et al. profile →

Peers

Countries citing papers authored by John E. Ladbury

Since Specialization

Citations

This map shows the geographic impact of John E. Ladbury's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John E. Ladbury with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John E. Ladbury more than expected).

Fields of papers citing papers by John E. Ladbury

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John E. Ladbury. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John E. Ladbury. The network helps show where John E. Ladbury may publish in the future.

Co-authorship network of co-authors of John E. Ladbury

This figure shows the co-authorship network connecting the top 25 collaborators of John E. Ladbury. A scholar is included among the top collaborators of John E. Ladbury based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John E. Ladbury. John E. Ladbury is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Glycogen myophosphorylase loss causes increased dependence on glucose in iPSC-derived retinal pigment epithelium 2024 ·Journal of Biological Chemistry ·Basudha Basu, (unknown), (unknown), Martin McKibbin, Kamron N. Khan, Chris F. Inglehearn, John E. Ladbury, Colin A. Johnson	0
2	E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer 2024 ·Oncogene ·Molly R. Patterson, (unknown), (unknown), (unknown), James A. Scarth, (unknown), (unknown), Christopher W. Wasson, (unknown), (unknown), (unknown), Claire D. James, Miao Wang, John E. Ladbury, Iain M. Morgan, Adel Samson, Ethan L. Morgan, Andrew Macdonald	3
3	The combined action of the intracellular regions regulates FGFR2 kinase activity 2023 ·Communications Biology ·Chi‐Chuan Lin, Łukasz Wieteska, G. Poncet-Montange, Kin Man Suen, Stefan T. Arold, Zamal Ahmed, John E. Ladbury	2
4	Grb2 binding induces phosphorylation-independent activation of Shp2 2021 ·Communications Biology ·Chi‐Chuan Lin, Łukasz Wieteska, Kin Man Suen, Arnout P. Kalverda, Zamal Ahmed, John E. Ladbury	21
5	DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans 2020 ·Nature Communications ·Kin Man Suen, (unknown), Richard Butler, Dalila Bensaddek, Alper Akay, Chi‐Chuan Lin, (unknown), (unknown), Alexandra Sapetschnig, Angus I. Lamond, John E. Ladbury, Eric A. Miska	16
6	Thermodynamic, kinetic, and structural parameterization of human carbonic anhydrase interactions toward enhanced inhibitor design 2018 ·Quarterly Reviews of Biophysics ·Vaida Linkuvienė, Asta Zubrienė, E. Manakova, Vytautas Petrauskas, Lina Baranauskienė, (unknown), А. В. Смирнов, S. Gražulis, John E. Ladbury, Daumantas Matulis	43
7	19F NMR Reveals Multiple Conformations at the Dimer Interface of the Nonstructural Protein 1 Effector Domain from Influenza A Virus 2014 ·Structure ·James M. Aramini, Keith Hamilton, Li-Chung Ma, G.V.T. Swapna, Paul G. Leonard, John E. Ladbury, Robert M. Krug, G.T. Montelione	44
8	A Requirement for ERK-Dependent Dicer Phosphorylation in Coordinating Oocyte-to-Embryo Transition in C. elegans 2014 ·Developmental Cell ·(unknown), Tokiko Furuta, Kin Man Suen, Gabriel González, Bin Liu, Awdhesh Kalia, John E. Ladbury, Andrew Fire, James B. Skeath, Swathi Arur	57
9	Structure and Interactions of the Human Programmed Cell Death 1 Receptor 2013 ·Journal of Biological Chemistry ·Xiaoxiao Cheng, Václav Veverka, Anand Radhakrishnan, Lorna C. Waters, Frederick W. Muskett, (unknown), Jiandong Huo, Chao Yu, Edward J. Evans, Alasdair Leslie, Meryn Griffiths, Colin Stubberfield, Robert Griffin, Alistair J. Henry, Andreas Jansson, John E. Ladbury, Shinji Ikemizu, Mark D. Carr, Simon J. Davis	263
10	Inhibition of Basal FGF Receptor Signaling by Dimeric Grb2 2012 ·Cell ·Chi‐Chuan Lin, Fernando A. Melo, (unknown), Kin Man Suen, Loren Stagg, John Kirkpatrick, Stefan T. Arold, Zamal Ahmed, John E. Ladbury	126
11	H-NS forms a superhelical protein scaffold for DNA condensation 2010 ·Proceedings of the National Academy of Sciences ·Stefan T. Arold, Paul G. Leonard, Gary N. Parkinson, John E. Ladbury	163
12	Enthalpic efficiency and the role of thermodynamic data in drug development: possibility or a pipeline dream! 2007 ·UCL Discovery (University College London) ·John E. Ladbury	3
13	Conformational Diversity in the TPR Domain-Mediated Interaction of Protein Phosphatase 5 with Hsp90 2006 ·Structure ·Matthew J. Cliff, Richard Harris, David Barford, John E. Ladbury, Mark A. Williams	68
14	Structural characterization of the N-terminal oligomerization domain of the bacterial chromatin-structuring protein, H-NS 2001 ·Journal of Molecular Biology ·Debora Renzoni, Diego Esposito, Mark Pfuhl, Jay C. D. Hinton, Christopher F. Higgins, Paul C. Driscoll, John E. Ladbury	32
15	Searching for specificity in SH domains 2000 ·Chemistry & Biology ·John E. Ladbury, Stefan T. Arold	89
16	Probing the nature of interactions in SH2 binding interfaces–evidence from electrospray ionization mass spectrometry 1999 ·Protein Science ·Evonne W. Chung, Denise Y. P. Henriques, Debora Renzoni, Craig J. Morton, Terrence D. Mulhern, Maureen Pitkeathly, John E. Ladbury, Carol V. Robinson	30
17	Identification and Structural Characterization of the ATP/ADP-Binding Site in the Hsp90 Molecular Chaperone breakdown → 1997 ·Cell ·Chrisostomos Prodromou, S. Mark Roe, Ronan O’Brien, John E. Ladbury, Peter W. Piper, Laurence H. Pearl	1058
18	CALORIES AND DESIGNER WATER 1996 ·Razi Journal of Medical Sciences ·John E. Ladbury	1
19	Substitution of Charged Residues into the Hydrophobic Core of Escherichia coli Thioredoxin Results in a Change in Heat Capacity of the Native Protein 1995 ·Biochemistry ·John E. Ladbury, Richard Wynn, James A. Thomson, Julian M. Sturtevant	23
20	Counting the calories to stay in the groove 1995 ·Structure ·John E. Ladbury	38

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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