Bruce D. Trapp

44.4k total citations · 11 hit papers
277 papers, 34.3k citations indexed

About

Bruce D. Trapp is a scholar working on Developmental Neuroscience, Cellular and Molecular Neuroscience and Pathology and Forensic Medicine. According to data from OpenAlex, Bruce D. Trapp has authored 277 papers receiving a total of 34.3k indexed citations (citations by other indexed papers that have themselves been cited), including 103 papers in Developmental Neuroscience, 89 papers in Cellular and Molecular Neuroscience and 87 papers in Pathology and Forensic Medicine. Recurrent topics in Bruce D. Trapp's work include Neurogenesis and neuroplasticity mechanisms (96 papers), Multiple Sclerosis Research Studies (80 papers) and Neuroinflammation and Neurodegeneration Mechanisms (53 papers). Bruce D. Trapp is often cited by papers focused on Neurogenesis and neuroplasticity mechanisms (96 papers), Multiple Sclerosis Research Studies (80 papers) and Neuroinflammation and Neurodegeneration Mechanisms (53 papers). Bruce D. Trapp collaborates with scholars based in United States, Canada and Germany. Bruce D. Trapp's co-authors include Richard A. Rudick, John W. Peterson, Sverre Mørk, Klaus‐Armin Nave, Ansi Chang, Richard M. Ransohoff, Lars Bø, Ranjan Dutta, Carl Bjartmar and Grahame J. Kidd and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Bruce D. Trapp

274 papers receiving 33.7k citations

Hit Papers

Axonal Transection in the Lesions of Multiple Sclerosis 1998 2026 2007 2016 1998 2008 2001 2015 2002 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Axonal Transection in the Lesions of Multiple Sclerosis
    1998 3.1k citations Bruce D. Trapp, John W. Peterson et al. New England Journal of Medicine profile →
  2. Multiple Sclerosis: An Immune or Neurodegenerative Disorder?
    2008 1.3k citations Bruce D. Trapp, Klaus‐Armin Nave profile →
  3. Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions
    2001 1.1k citations John W. Peterson, Lars Eirik Bø et al. Annals of Neurology profile →
  4. Pathological mechanisms in progressive multiple sclerosis
    2015 865 citations Bruce D. Trapp et al. profile →
  5. Premyelinating Oligodendrocytes in Chronic Lesions of Multiple Sclerosis
    2002 770 citations Ansi Chang, Richard A. Rudick et al. New England Journal of Medicine profile →
  6. Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients
    2006 647 citations Ranjan Dutta, Xinghua Yin et al. Annals of Neurology profile →
  7. NG2-Positive Oligodendrocyte Progenitor Cells in Adult Human Brain and Multiple Sclerosis Lesions
    2000 574 citations Ansi Chang, Akiko Nishiyama et al. Journal of Neuroscience profile →
  8. Subpial Demyelination in the Cerebral Cortex of Multiple Sclerosis Patients
    2003 552 citations Lars Bø, Bruce D. Trapp et al. profile →
  9. Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis
    2009 481 citations Bruce D. Trapp et al. profile →
  10. Activation of Necroptosis in Multiple Sclerosis
    2015 419 citations Dimitry Ofengeim, Ansi Chang et al. profile →
  11. Target identification among known drugs by deep learning from heterogeneous networks
    2020 257 citations Bruce D. Trapp et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Bruce D. Trapp United States 94 12.1k 11.3k 8.7k 8.4k 8.3k 277 34.3k
Jack P. Antel Canada 102 12.9k 1.1× 11.1k 1.0× 4.9k 0.6× 3.9k 0.5× 10.9k 1.3× 525 38.0k
Wolfgang Brück Germany 89 14.7k 1.2× 7.7k 0.7× 4.8k 0.6× 3.9k 0.5× 8.4k 1.0× 391 32.1k
Cedric S. Raine United States 88 9.2k 0.8× 8.5k 0.8× 4.6k 0.5× 4.2k 0.5× 7.1k 0.9× 413 31.5k
Robin J.M. Franklin United Kingdom 89 6.4k 0.5× 9.7k 0.9× 14.7k 1.7× 8.0k 0.9× 10.0k 1.2× 293 29.1k
Richard M. Ransohoff United States 116 9.8k 0.8× 12.2k 1.1× 5.1k 0.6× 5.9k 0.7× 23.5k 2.8× 352 54.3k
Michal Schwartz Israel 93 4.6k 0.4× 7.9k 0.7× 5.6k 0.6× 7.7k 0.9× 16.8k 2.0× 301 32.6k
Gıancarlo Comı Italy 95 17.6k 1.5× 6.3k 0.6× 3.1k 0.4× 3.6k 0.4× 5.1k 0.6× 762 36.2k
Hans Lassmann Austria 145 30.8k 2.5× 18.7k 1.7× 9.0k 1.0× 8.7k 1.0× 18.1k 2.2× 645 70.7k
Hans‐Peter Hartung Germany 89 20.7k 1.7× 7.9k 0.7× 2.1k 0.2× 6.5k 0.8× 4.7k 0.6× 730 43.0k
Michael Chopp United States 131 3.2k 0.3× 26.2k 2.3× 13.6k 1.6× 11.5k 1.4× 16.5k 2.0× 815 66.4k

Countries citing papers authored by Bruce D. Trapp

Since Specialization
Citations

This map shows the geographic impact of Bruce D. Trapp's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bruce D. Trapp with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bruce D. Trapp more than expected).

Fields of papers citing papers by Bruce D. Trapp

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bruce D. Trapp. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bruce D. Trapp. The network helps show where Bruce D. Trapp may publish in the future.

Co-authorship network of co-authors of Bruce D. Trapp

This figure shows the co-authorship network connecting the top 25 collaborators of Bruce D. Trapp. A scholar is included among the top collaborators of Bruce D. Trapp based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Bruce D. Trapp. Bruce D. Trapp is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
2.
Tong, Lingying, et al.. (2025). AAV1.NT3 gene therapy mitigates the severity of autoimmune encephalomyelitis in the mouse model for multiple sclerosis. Gene Therapy. 32(4). 410–420. 1 indexed citations
3.
Gruber, Ross C., Michael R. Dufault, Nellwyn Hagan, et al.. (2024). BTK regulates microglial function and neuroinflammation in human stem cell models and mouse models of multiple sclerosis. Nature Communications. 15(1). 10116–10116. 11 indexed citations
4.
Ghezzi, Laura, Bryan Bollman, Laura Piccio, et al.. (2023). Schwann Cell Remyelination in the Multiple Sclerosis Central Nervous System. Laboratory Investigation. 103(6). 100128–100128. 6 indexed citations
5.
Cuenda, Ana, Fraser J. Sim, Alberto González-Aguilar, et al.. (2023). p38γ MAPK delays myelination and remyelination and is abundant in multiple sclerosis lesions. Brain. 147(5). 1871–1886. 6 indexed citations
6.
Dutta, Ranjan, Kedar Mahajan, Kunio Nakamura, et al.. (2019). Comprehensive Autopsy Program for Individuals with Multiple Sclerosis. Journal of Visualized Experiments. 15 indexed citations
7.
He, Xuelian, Liguo Zhang, Luis F. Queme, et al.. (2018). A histone deacetylase 3–dependent pathway delimits peripheral myelin growth and functional regeneration. Nature Medicine. 24(3). 338–351. 81 indexed citations
8.
Avila, Robin L., Jing Wang, Emily Benson, et al.. (2015). Fingolimod reduces axonal transection during demyelination (P1.153). Neurology. 84(14_supplement). 4 indexed citations
9.
Kang, Zizhen, Chenhui Wang, Jarod A. Zepp, et al.. (2013). Act1 mediates IL-17–induced EAE pathogenesis selectively in NG2+ glial cells. Nature Neuroscience. 16(10). 1401–1408. 172 indexed citations
10.
Jalabi, Walid, Ranjan Dutta, Yongming Jin, et al.. (2009). Endotoxin Preconditioning of the CNS: Microglia Activation and Neuroprotection. Cleveland Clinic Journal of Medicine. 76. 1 indexed citations
11.
Yin, Xinghua, et al.. (2008). P0Protein Is Required for and Can Induce Formation of Schmidt-Lantermann Incisures in Myelin Internodes. Journal of Neuroscience. 28(28). 7068–7073. 19 indexed citations
12.
Moll, Natalia, Anna Rietsch, Amy Ransohoff, et al.. (2007). Cortical demyelination in PML and MS. Neurology. 70(5). 336–343. 91 indexed citations
13.
Greco, Claudia, Robert F. Berman, Richard M. Martin, et al.. (2005). Neuropathology of fragile X-associated tremor/ataxia syndrome (FXTAS). Brain. 129(1). 243–255. 388 indexed citations
14.
Forsberg‐Nilsson, Karin, Anna Erlandsson, Xiaoqun Zhang, et al.. (2003). Oligodendrocyte precursor hypercellularity and abnormal retina development in mice overexpressing PDGF‐B in myelinating tracts. Glia. 41(3). 276–289. 15 indexed citations
15.
Bjartmar, Carl & Bruce D. Trapp. (2001). Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences. Current Opinion in Neurology. 14(3). 271–278. 388 indexed citations
16.
Peterson, John W., Lars Eirik Bø, Sverre Mørk, Ansi Chang, & Bruce D. Trapp. (2001). Transected neurites, apoptotic neurons, and reduced inflammation in cortical multiple sclerosis lesions. Annals of Neurology. 50(3). 389–400. 1083 indexed citations breakdown →
17.
Trapp, Bruce D., John W. Peterson, Richard M. Ransohoff, et al.. (1998). Axonal Transection in the Lesions of Multiple Sclerosis. New England Journal of Medicine. 338(5). 278–285. 3125 indexed citations breakdown →
18.
Ikezu, Tsuneya, Bruce D. Trapp, Kenneth Song, et al.. (1998). Caveolae, Plasma Membrane Microdomains for α-Secretase-mediated Processing of the Amyloid Precursor Protein. Journal of Biological Chemistry. 273(17). 10485–10495. 136 indexed citations
19.
Yu, Canqing, Akiko Nishiyama, Bruce D. Trapp, & Vincent K. Tuohy. (1996). Interferon-β inhibits progression of relapsing-remitting experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 64(1). 91–100. 125 indexed citations
20.
Ilyas, Amjad A., Hugh J. Willison, Richard H. Quarles, et al.. (1988). Serum antibodies to gangliosides in guillain‐barré syndrome. Annals of Neurology. 23(5). 440–447. 224 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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