Weiming Xia

17.1k total citations · 2 hit papers
166 papers, 11.6k citations indexed

About

Weiming Xia is a scholar working on Physiology, Molecular Biology and Pharmacology. According to data from OpenAlex, Weiming Xia has authored 166 papers receiving a total of 11.6k indexed citations (citations by other indexed papers that have themselves been cited), including 107 papers in Physiology, 68 papers in Molecular Biology and 27 papers in Pharmacology. Recurrent topics in Weiming Xia's work include Alzheimer's disease research and treatments (104 papers), Cholinesterase and Neurodegenerative Diseases (27 papers) and Dementia and Cognitive Impairment Research (16 papers). Weiming Xia is often cited by papers focused on Alzheimer's disease research and treatments (104 papers), Cholinesterase and Neurodegenerative Diseases (27 papers) and Dementia and Cognitive Impairment Research (16 papers). Weiming Xia collaborates with scholars based in United States, China and Canada. Weiming Xia's co-authors include Dennis J. Selkoe, Michael S. Wolfe, Beth L. Ostaszewski, W. Taylor Kimberly, Thekla S. Diehl, Edward H. Koo, Dennis J. Selkoe, Susumu Tonegawa, Dongfeng Chen and Jie Shen and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Weiming Xia

160 papers receiving 11.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity

1999 1.6k citations Michael S. Wolfe, Weiming Xia et al. profile →
Skeletal and CNS Defects in Presenilin-1-Deficient Mice

1997 770 citations Weiming Xia et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Weiming Xia United States	48	7.0k	5.7k	2.1k	2.1k	1.9k	166	11.6k
Jochen Walter Germany	60	6.0k 0.9×	5.3k 0.9×	2.3k 1.1×	1.5k 0.7×	1.6k 0.9×	148	11.6k
Yadong Huang United States	63	6.9k 1.0×	5.3k 0.9×	2.7k 1.3×	1.5k 0.7×	686 0.4×	143	13.9k
Thomas A. Bayer Germany	67	6.9k 1.0×	4.3k 0.8×	2.6k 1.2×	1.6k 0.8×	689 0.4×	246	12.9k
Harald Steiner Germany	57	6.4k 0.9×	5.5k 1.0×	1.4k 0.7×	1.9k 0.9×	2.2k 1.2×	203	10.3k
Gerald A. Higgins United States	34	5.7k 0.8×	4.0k 0.7×	2.6k 1.2×	1.5k 0.7×	875 0.5×	93	10.8k
Hiroshi Mori Japan	54	6.6k 0.9×	4.6k 0.8×	2.0k 0.9×	1.3k 0.7×	904 0.5×	273	12.3k
Gail V.W. Johnson United States	68	5.9k 0.8×	7.6k 1.3×	4.0k 1.9×	1.4k 0.7×	2.8k 1.5×	228	15.5k
Seth Love United Kingdom	67	6.9k 1.0×	4.7k 0.8×	2.7k 1.3×	1.2k 0.6×	743 0.4×	319	16.8k
David H. Cribbs United States	53	5.8k 0.8×	3.9k 0.7×	2.3k 1.1×	1.3k 0.6×	581 0.3×	164	11.1k
Jürgen Götz Australia	77	12.3k 1.7×	9.7k 1.7×	5.2k 2.5×	3.0k 1.4×	1.9k 1.0×	243	21.7k

Countries citing papers authored by Weiming Xia

Since Specialization

Citations

This map shows the geographic impact of Weiming Xia's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Weiming Xia with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Weiming Xia more than expected).

Fields of papers citing papers by Weiming Xia

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Weiming Xia. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Weiming Xia. The network helps show where Weiming Xia may publish in the future.

Co-authorship network of co-authors of Weiming Xia

This figure shows the co-authorship network connecting the top 25 collaborators of Weiming Xia. A scholar is included among the top collaborators of Weiming Xia based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Weiming Xia. Weiming Xia is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Subramanian, Manju L., Konstantina Sampani, Steven Ness, et al.. (2025). Biomarkers for Alzheimer's disease are upregulated in patients with diabetic retinopathy. Journal of Alzheimer s Disease. 108(2). 586–596.

Querfurth, Henry, et al.. (2025). Target Validation Studies of PS48, a PDK-1 Allosteric Agonist, for the Treatment of Alzheimer’s Disease Phenotype in APP/PS1 Transgenic Mice. International Journal of Molecular Sciences. 26(8). 3473–3473.

Sampani, Konstantina, Steven Ness, Nurgül Aytan, et al.. (2024). Neurodegenerative biomarkers in different chambers of the eye relative to plasma: an agreement validation study. Alzheimer s Research & Therapy. 16(1). 192–192. 12 indexed citations

Qi, Shaohua, Yang Li, Xuping Li, et al.. (2023). Lipidomic dysfunction accompanied phosphatidylethanolamine deregulation is a potential detection biomarker and drug target for early Alzheimer’s disease of obesity population. Alzheimer s & Dementia. 19(S21).

Zhou, John, Qi Shi, Wanxia He, et al.. (2023). Reticulons 1 and 3 are essential for axonal growth and synaptic maintenance associated with intellectual development. Human Molecular Genetics. 32(16). 2587–2599. 2 indexed citations

Garg, Itika, Jia Xu, Yorghos Tripodis, et al.. (2023). Vitreous Humor Biomarkers Reflect Pathological Changes in the Brain for Alzheimer’s Disease and Chronic Traumatic Encephalopathy. Journal of Alzheimer s Disease. 93(3). 1181–1193. 10 indexed citations

Cherry, Jonathan D., Weiming Xia, Sarah Daley, et al.. (2023). Vascular injury is associated with repetitive head impacts and tau pathology in chronic traumatic encephalopathy. Journal of Neuropathology & Experimental Neurology. 82(2). 127–139. 11 indexed citations

Wei, Wei, et al.. (2022). The mevalonate suppressor δ-tocotrienol increases AMPA receptor-mediated neurotransmission. Biochemical and Biophysical Research Communications. 638. 112–119. 2 indexed citations

Chung, Jaeyoon, Congcong Zhu, Gaoyuan Meng, et al.. (2021). Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease. Molecular Psychiatry. 26(10). 6054–6064. 30 indexed citations

10.

Zhou, Xianxiao, Mei Chen, Weiming Xia, et al.. (2021). Lifelong chronic psychosocial stress induces a proteomic signature of Alzheimer's disease in wildtype mice. European Journal of Neuroscience. 55(9-10). 2971–2985. 10 indexed citations

11.

Zhao, Jing, Xinyue Liu, Weiming Xia, Yingkai Zhang, & Chunyu Wang. (2020). Targeting Amyloidogenic Processing of APP in Alzheimer’s Disease. Frontiers in Molecular Neuroscience. 13. 137–137. 112 indexed citations

12.

Muraoka, Satoshi, Weiwei Lin, Mei Chen, et al.. (2020). Assessment of separation methods for extracellular vesicles from human and mouse brain tissues and human cerebrospinal fluids. Methods. 177. 35–49. 44 indexed citations

13.

Cherry, Jonathan D., Gaoyuan Meng, Sarah Daley, et al.. (2020). CCL2 is associated with microglia and macrophage recruitment in chronic traumatic encephalopathy. Journal of Neuroinflammation. 17(1). 370–370. 50 indexed citations

14.

Song, Hailong, Mei Chen, Chen Chen, et al.. (2018). Proteomic Analysis and Biochemical Correlates of Mitochondrial Dysfunction after Low-Intensity Primary Blast Exposure. Journal of Neurotrauma. 36(10). 1591–1605. 33 indexed citations

15.

Yu, Deshui, et al.. (2018). Kongenitale Hypofibrinogenämie in Verbindung mit γK232T: in vitro-Expression zeigt mangelhafte Sekretion der Fibrinogen-Variante. Hämostaseologie. 38. 1 indexed citations

16.

Yang, Ting, et al.. (2010). Phenotypic analysis of images of zebrafish treated with Alzheimer's γ-secretase inhibitors. BMC Biotechnology. 10(1). 24–24. 32 indexed citations

17.

Dong, Yuanlin, Guohua Zhang, Bin Zhang, et al.. (2009). The Common Inhalational Anesthetic Sevoflurane Induces Apoptosis and Increases β-Amyloid Protein Levels. Archives of Neurology. 66(5). 620–31. 228 indexed citations

18.

Xia, Weiming. (2008). From Presenilinase to γ-Secretase, Cleave to Capacitate. Current Alzheimer Research. 5(2). 172–178. 16 indexed citations

19.

Xie, Zhongcong, Yuanlin Dong, Uta Maeda, et al.. (2007). The Inhalation Anesthetic Isoflurane Induces a Vicious Cycle of Apoptosis and Amyloid β-Protein Accumulation. Journal of Neuroscience. 27(6). 1247–1254. 187 indexed citations

20.

Campbell, William A., et al.. (2003). Presenilin endoproteolysis mediated by an aspartyl protease activity pharmacologically distinct from γ‐secretase. Journal of Neurochemistry. 85(6). 1563–1574. 32 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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