Rik Ossenkoppele

27.9k total citations · 12 hit papers
272 papers, 10.8k citations indexed

About

Rik Ossenkoppele is a scholar working on Psychiatry and Mental health, Physiology and Cognitive Neuroscience. According to data from OpenAlex, Rik Ossenkoppele has authored 272 papers receiving a total of 10.8k indexed citations (citations by other indexed papers that have themselves been cited), including 197 papers in Psychiatry and Mental health, 145 papers in Physiology and 74 papers in Cognitive Neuroscience. Recurrent topics in Rik Ossenkoppele's work include Dementia and Cognitive Impairment Research (192 papers), Alzheimer's disease research and treatments (144 papers) and Functional Brain Connectivity Studies (64 papers). Rik Ossenkoppele is often cited by papers focused on Dementia and Cognitive Impairment Research (192 papers), Alzheimer's disease research and treatments (144 papers) and Functional Brain Connectivity Studies (64 papers). Rik Ossenkoppele collaborates with scholars based in Netherlands, Sweden and United States. Rik Ossenkoppele's co-authors include Oskar Hansson, Philip Scheltens, Wiesje M. van der Flier, Rik van der Kant, Bart N.M. van Berckel, Gil D. Rabinovici, Ruben Smith, Olof Strandberg, Frederik Barkhof and Jacob W. Vogel and has published in prestigious journals such as The Lancet, Nature Medicine and Nature Communications.

In The Last Decade

Rik Ossenkoppele

250 papers receiving 10.7k citations

Hit Papers

PET Imaging of Tau Deposition in the Aging Human Brain 2015 2026 2018 2022 2016 2016 2015 2019 2021 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. PET Imaging of Tau Deposition in the Aging Human Brain
    2016 790 citations Michael Schöll, Rik Ossenkoppele et al. profile →
  2. Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease
    2016 779 citations Rik Ossenkoppele, Michael Schöll et al. Brain profile →
  3. The effect of physical activity on cognitive function in patients with dementia: A meta-analysis of randomized control trials
    2015 430 citations Colin Groot, Bart N.M. van Berckel et al. profile →
  4. Amyloid-β-independent regulators of tau pathology in Alzheimer disease
    2019 423 citations Rik van der Kant, Rik Ossenkoppele et al. Nature reviews. Neuroscience profile →
  5. Four distinct trajectories of tau deposition identified in Alzheimer’s disease
    2021 400 citations Jacob W. Vogel, Alexandra L. Young et al. Nature Medicine profile →
  6. Tau biomarkers in Alzheimer's disease: towards implementation in clinical practice and trials
    2022 292 citations Rik Ossenkoppele, Rik van der Kant et al. profile →
  7. The probabilistic model of Alzheimer disease: the amyloid hypothesis revised
    2021 290 citations Giovanni B. Frisoni, Daniele Altomare et al. Nature reviews. Neuroscience profile →
  8. Aβ deposition is associated with increases in soluble and phosphorylated tau that precede a positive Tau PET in Alzheimer’s disease
    2020 217 citations Niklas Mattsson, Shorena Janelidze et al. profile →
  9. Prediction of Longitudinal Cognitive Decline in Preclinical Alzheimer Disease Using Plasma Biomarkers
    2023 150 citations Niklas Mattsson, Gemma Salvadó et al. JAMA Neurology profile →
  10. Specific associations between plasma biomarkers and postmortem amyloid plaque and tau tangle loads
    2023 92 citations Gemma Salvadó, Rik Ossenkoppele et al. profile →
  11. Disease staging of Alzheimer’s disease using a CSF-based biomarker model
    2024 49 citations Gemma Salvadó, Jacob W. Vogel et al. profile →
  12. Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease
    2025 27 citations Gemma Salvadó, Shorena Janelidze et al. Nature Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Rik Ossenkoppele Netherlands 56 6.6k 6.0k 3.2k 1.9k 1.7k 272 10.8k
Pieter Jelle Visser Netherlands 56 6.5k 1.0× 8.2k 1.4× 3.4k 1.1× 1.8k 1.0× 2.3k 1.4× 301 13.8k
Heather J. Wiste United States 44 6.1k 0.9× 6.0k 1.0× 2.8k 0.9× 1.9k 1.0× 1.5k 0.9× 108 11.0k
Mary M. Machulda United States 62 5.7k 0.9× 6.9k 1.1× 5.2k 1.6× 2.0k 1.1× 1.7k 1.0× 354 13.6k
David T. Jones United States 49 4.2k 0.6× 3.7k 0.6× 3.3k 1.0× 1.9k 1.0× 1.2k 0.7× 193 10.1k
Sebastian Palmqvist Sweden 51 7.3k 1.1× 6.4k 1.1× 2.0k 0.6× 993 0.5× 2.2k 1.3× 183 10.8k
Gene E. Alexander United States 62 5.0k 0.8× 4.5k 0.8× 3.9k 1.2× 2.2k 1.1× 1.5k 0.9× 175 11.7k
David A. Wolk United States 56 4.1k 0.6× 4.6k 0.8× 3.5k 1.1× 1.9k 1.0× 1.8k 1.1× 272 10.3k
Suzanne L. Baker United States 44 4.9k 0.8× 4.5k 0.7× 3.7k 1.2× 1.7k 0.9× 1.1k 0.7× 135 8.6k
Erik Stomrud Sweden 52 7.4k 1.1× 6.2k 1.0× 1.9k 0.6× 966 0.5× 2.3k 1.4× 189 11.1k
Eric Westman Sweden 56 3.5k 0.5× 4.1k 0.7× 3.0k 0.9× 1.9k 1.0× 1.8k 1.1× 288 9.5k

Countries citing papers authored by Rik Ossenkoppele

Since Specialization
Citations

This map shows the geographic impact of Rik Ossenkoppele's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Rik Ossenkoppele with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Rik Ossenkoppele more than expected).

Fields of papers citing papers by Rik Ossenkoppele

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Rik Ossenkoppele. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Rik Ossenkoppele. The network helps show where Rik Ossenkoppele may publish in the future.

Co-authorship network of co-authors of Rik Ossenkoppele

This figure shows the co-authorship network connecting the top 25 collaborators of Rik Ossenkoppele. A scholar is included among the top collaborators of Rik Ossenkoppele based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Rik Ossenkoppele. Rik Ossenkoppele is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Mastenbroek, Sophie E, Lyduine E. Collij, Alexandra L. Young, et al.. (2025). Biological classification of memory clinic patients. Brain.
2.
Calandri, Ismael Luis, Frederik Barkhof, Rik Ossenkoppele, et al.. (2025). Amygdalar and hippocampal volume loss in limbic-predominant age-related TDP-43 encephalopathy. Brain. 148(11). 3913–3923. 2 indexed citations
3.
Mastenbroek, Sophie E, Jacob W. Vogel, Lyduine E. Collij, et al.. (2024). Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology. Nature Communications. 15(1). 5133–5133. 30 indexed citations
4.
Ossenkoppele, Rik & Charlotte E. Teunissen. (2024). Fluid Biomarker Changes After Amyloid-β–Targeting Drugs. JAMA Neurology. 81(6). 579–579.
5.
Svenningsson, Anna L., Erik Stomrud, Frederik Barkhof, et al.. (2024). Biological mechanisms of resilience to tau pathology in Alzheimer’s disease. Alzheimer s Research & Therapy. 16(1). 221–221.
6.
Crane, Paul K., Colin Groot, Rik Ossenkoppele, et al.. (2023). Cognitively defined Alzheimer's dementia subgroups have distinct atrophy patterns. Alzheimer s & Dementia. 20(3). 1739–1752. 8 indexed citations
7.
Coomans, Emma M., Sander C.J. Verfaillie, Denise Visser, et al.. (2023). Performance of a [ 18 F]Flortaucipir PET Visual Read Method Across the Alzheimer Disease Continuum and in Dementia With Lewy Bodies. Neurology. 101(19). e1850–e1862. 11 indexed citations
8.
Coomans, Emma M., Danielle van Westen, Alexa Pichet Binette, et al.. (2023). Interactions between vascular burden and amyloid-β pathology on trajectories of tau accumulation. Brain. 147(3). 949–960. 23 indexed citations
9.
Salvadó, Gemma, Victoria Larsson, Karly Alex Cody, et al.. (2023). Optimal combinations of CSF biomarkers for predicting cognitive decline and clinical conversion in cognitively unimpaired participants and mild cognitive impairment patients: A multi‐cohort study. Alzheimer s & Dementia. 19(7). 2943–2955. 24 indexed citations
10.
Vogel, Jacob W., Alexandra L. Young, Neil P. Oxtoby, et al.. (2021). Four distinct trajectories of tau deposition identified in Alzheimer’s disease. Nature Medicine. 27(5). 871–881. 400 indexed citations breakdown →
11.
Eikelboom, Willem S., Rik Ossenkoppele, Michiel Coesmans, et al.. (2021). Sex differences in neuropsychiatric symptoms in Alzheimer’s disease dementia: A meta‐analysis. Alzheimer s & Dementia. 17(S6). 10 indexed citations
12.
Groot, Colin, Michel J. Grothe, Shubhabrata Mukherjee, et al.. (2021). Differential patterns of gray matter volumes and associated gene expression profiles in cognitively-defined Alzheimer’s disease subgroups. NeuroImage Clinical. 30. 102660–102660. 15 indexed citations
13.
Frisoni, Giovanni B., Daniele Altomare, Dietmar Rudolf Thal, et al.. (2021). The probabilistic model of Alzheimer disease: the amyloid hypothesis revised. Nature reviews. Neuroscience. 23(1). 53–66. 290 indexed citations breakdown →
14.
Chiotis, Konstantinos, Alessandra Dodich, Marina Boccardi, et al.. (2021). Clinical validity of increased cortical binding of tau ligands of the THK family and PBB3 on PET as biomarkers for Alzheimer’s disease in the context of a structured 5-phase development framework. European Journal of Nuclear Medicine and Molecular Imaging. 48(7). 2086–2096. 10 indexed citations
15.
Salvadó, Gemma, et al.. (2021). Differential associations of APOE-epsilon 2 and APOE-epsilon 4 alleles with PET-measured amyloid-beta and tau deposition in older individuals without dementia. UCL Discovery (University College London). 2 indexed citations
16.
Groot, Colin, B.T. Thomas Yeo, Jacob W. Vogel, et al.. (2020). Latent atrophy factors related to phenotypical variants of posterior cortical atrophy. Neurology. 95(12). e1672–e1685. 21 indexed citations
17.
Reimand, Juhan, et al.. (2020). Association of amyloid-β CSF/PET discordance and tau load 5 years later. Neurology. 95(19). e2648–e2657. 31 indexed citations
18.
Groot, Colin, Vincent Doré, Joanne Robertson, et al.. (2020). Mesial temporal tau is related to worse cognitive performance and greater neocortical tau load in amyloid-β–negative cognitively normal individuals. Neurobiology of Aging. 97. 41–48. 21 indexed citations
19.
Ossenkoppele, Rik, Chul Hyoung Lyoo, Carole H. Sudre, et al.. (2019). Distinct tau PET patterns in atrophy‐defined subtypes of Alzheimer's disease. Alzheimer s & Dementia. 16(2). 335–344. 77 indexed citations
20.
Adriaanse, Sofie M., Alle Meije Wink, Betty M. Tijms, et al.. (2015). The Association of Glucose Metabolism and Eigenvector Centrality in Alzheimer's Disease. Brain Connectivity. 6(1). 1–8. 16 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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