Frédéric J. Zécri

2.4k citations

33 papers · 1.4k indexed · h-index 19

Organic Chemistry top 5%
- Synthetic Organic Chemistry Methods 5
- Carbohydrate Chemistry and Synthesis 5
- Click Chemistry and Applications 4
Molecular Biology top 10%
- Chemical Synthesis and Analysis 6
- Sphingolipid Metabolism and Signaling 6
- Protein Degradation and Inhibitors 4
- RNA modifications and cancer 3
Pharmaceutical Science top 10%
Pharmacology top 10%
- Microbial Natural Products and Biosynthesis 3
Genetics

Co-authors: Danilo Guerini Florian Müllershausen Klaus Seuwen Andreas Billich Simone Bonazzi Anthony G. M. Barrett Kaila A. Margrey Joshua B. McManus
Cited by: Organic Chemistry Molecular Biology Pharmaceutical Science
Journals: Journal of the American Chemical Society (4 papers)Angewandte Chemie International Edition (3 papers)Diabetes (1 paper)
Partner nations: Switzerland United States China

In The Last Decade

Frédéric J. Zécri

32 papers receiving 1.4k citations

Peers

Countries citing papers authored by Frédéric J. Zécri

Since Specialization

Citations

This map shows the geographic impact of Frédéric J. Zécri's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frédéric J. Zécri with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frédéric J. Zécri more than expected).

Fields of papers citing papers by Frédéric J. Zécri

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frédéric J. Zécri. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frédéric J. Zécri. The network helps show where Frédéric J. Zécri may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Frédéric J. Zécri, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Frédéric J. Zécri Line = papers co-authored together Frédéric J. Zécri links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Development of an FKBP12-recruiting chemical-induced proximity DNA-encoded library and its application to discover an autophagy potentiator Cell chemical biology ·Zher Yin Tan,Joel K.A. Adade,Xiebin Gu,Cody Hecht,Michael Salcius,Bingqi Tong,Shuang Liu,Seungmin Hwang,Frédéric J. Zécri,Daniel B. Graham,Stuart L. Schreiber,Ramnik J. Xavier	2025	6
2	Selectivity Profiling of Bromodomain PROTACs Using Chemical Inducers of Proximity DNA-Encoded Library Screening ACS Chemical Biology ·Yuen Ting Chow,Bingqi Tong,Zher Yin Tan,Antonin Tutter,Zhirun Nan,Patricia A. Horton,M.J. Romanowski,Frédéric J. Zécri,Stuart L. Schreiber,Shuang Liu	2025	0
3	DNA-encoded library-enabled discovery of proximity-inducing small molecules Nature Chemical Biology ·Jeremy W. Mason,Yuen Ting Chow,Liam Hudson,Antonin Tutter,Gregory A. Michaud,Matthias V. Westphal,Wei Shu,Xiaolei Ma,Zher Yin Tan,Connor W. Coley,Paul A. Clemons,Simone Bonazzi,Frédéric Berst,Karin Briner,Shuang Liu,Frédéric J. Zécri,Stuart L. Schreiber	2023	41
4	Rational Screening for Cooperativity in Small-Molecule Inducers of Protein–Protein Associations Journal of the American Chemical Society ·Shuang Liu,Bingqi Tong,Jeremy W. Mason,J.M. Ostrem,Antonin Tutter,Bruce K. Hua,Sunny A. Tang,Simone Bonazzi,Karin Briner,Frédéric Berst,Frédéric J. Zécri,Stuart L. Schreiber	2023	35
5	Modular Synthesis of Cyclopropane‐Fused N‐Heterocycles Enabled by Underexplored Diazo Reagents Angewandte Chemie International Edition ·Matthieu J. R. Richter,Frédéric J. Zécri,Karin Briner,Stuart L. Schreiber	2022	12
6	Successful Strategies for Mitigation of a Preclinical Signal for Phototoxicity in a DGAT1 Inhibitor ACS Medicinal Chemistry Letters ·Tyler Harrison,Daniel Bauer,Alina Berdichevsky,Xin Chen,Rohit Duvadie,Benjamin Hoogheem,Panos Hatsis,Qian Liu,Justin Mao,Vasumathy Miduturu,Erik C. Rocheford,Frédéric J. Zécri,Richard Zessis,Rui Zheng,Qingming Zhu,Ryan S. Streeper,Sejal Patel	2019	6
7	3′-Modification stabilizes mRNA and increases translation in cells Bioorganic & Medicinal Chemistry Letters ·Christian M. Gampe,Amy C. Seila White,S Nayak Siva,Frédéric J. Zécri,John L. Diener	2018	7
8	Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors ACS Medicinal Chemistry Letters ·Klemens Hoegenauer,Nicolas Soldermann,Frédéric J. Zécri,Ross Strang,Nadège Graveleau,Romain M. Wolf,Nigel G. Cooke,Alexander B. Smith,Gregory J. Hollingworth,Joachim Blanz,Sascha Gutmann,Gabriele Rummel,Amanda Littlewood‐Evans,Christoph Burkhart	2017	84
9	Medicinal Chemistry Profiling of Monocyclic 1,2‐Azaborines ChemMedChem ·Peng Zhao,David O. Nettleton,Rajeshri G. Karki,Frédéric J. Zécri,Shih‐Yuan Liu	2017	97
10	Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties Bioorganic & Medicinal Chemistry Letters ·Klemens Hoegenauer,Nicolas Soldermann,Christina Hebach,Gregory J. Hollingworth,Ian Lewis,Anette von Matt,Alexander B. Smith,Romain M. Wolf,Rainer Wilcken,Dorothea Haasen,Christoph Burkhart,Frédéric J. Zécri	2016	17
11	From Natural Product to the First Oral Treatment for Multiple Sclerosis: The Discovery of FTY720 (Gilenya™)? Current Opinion in Chemical Biology ·Frédéric J. Zécri	2016	22
12	Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors ACS Medicinal Chemistry Letters ·Klemens Hoegenauer,Nicolas Soldermann,Frédéric Stauffer,Pascal Furet,Nadège Graveleau,Alexander B. Smith,Christina Hebach,Gregory J. Hollingworth,Ian Lewis,Sascha Gutmann,Gabriele Rummel,Mark Knapp,Romain M. Wolf,Joachim Blanz,Roland Feifel,Christoph Burkhart,Frédéric J. Zécri	2016	49
13	Covalent Chemical 5′‐Functionalization of RNA with Diazo Reagents Angewandte Chemie International Edition ·Christian M. Gampe,Micah Hollis‐Symynkywicz,Frédéric J. Zécri	2016	18
14	The design and implementation of a generic lipopeptide scanning platform to enable the identification of ‘locally acting’ agonists for the apelin receptor Bioorganic & Medicinal Chemistry Letters ·Stephen C. McKeown,Frédéric J. Zécri,E. Fortier,Andrew K.P. Taggart,Lilya Sviridenko,Christopher M. Adams,Kathryn H. McAllister,Sokhom S. Pin	2014	12
15	Absorption and Disposition of the Sphingosine 1-Phosphate Receptor Modulator Fingolimod (FTY720) in Healthy Volunteers: A Case of Xenobiotic Biotransformation Following Endogenous Metabolic Pathways Drug Metabolism and Disposition ·Markus Zollinger,Hans-Peter Gschwind,Yi Jin,Claudia Sayer,Frédéric J. Zécri,Stefan Hartmann	2010	40
16	Pyrazole derived from (+)-3-carene; a novel potent, selective scaffold for sphingosine-1-phosphate (S1P1) receptor agonists Bioorganic & Medicinal Chemistry Letters ·Frédéric J. Zécri,Rainer Albert,Gregory A. Landrum,Klaus Hinterding,Nigel G. Cooke,Danilo Guerini,Markus Streiff,Christian Bruns,Barbara Nuesslein‐Hildesheim	2009	6
17	Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors Nature Chemical Biology ·Florian Müllershausen,Frédéric J. Zécri,Cihan Cetin,Andreas Billich,Danilo Guerini,Klaus Seuwen	2009	306
18	Stereocontrolled Synthesis of the Quinaldic Acid Macrocyclic System of Thiostrepton We thank Drs. D. H. Huang and G. Suizdak for NMR spectroscopic and mass spectrometric assistance, respectively, as well as Mike Sertic (University of California, San Diego) for experimental assistance. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), fellowships from The Skaggs Institute for Research (to M.Z. and F.Z.), and grants from Abbott, Amgen, Array Biopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. Angewandte Chemie ·K. C. Nicolaou,Brian S. Safina,Christian Funke,Mark Zak,Frédéric J. Zécri	2002	15
19	Chromatography-Free Synthesis of 1,2,4-Oxadiazoles Using ROMPGEL-Supported Acylating Reagents Combinatorial Chemistry & High Throughput Screening ·Amy Barrett,Susan M. Cramp,Richard S. Roberts,Frédéric J. Zécri	2000	14
20	ROMPGEL Scavengers: A High-Loading Supported Anhydride for Sequestering Amines and Hydrazines Organic Letters ·Thomas Arnauld,Anthony G. M. Barrett,Susan M. Cramp,Richard S. Roberts,Frédéric J. Zécri	2000	17

About Frédéric J. Zécri

Frédéric J. Zécri is a scholar working on Organic Chemistry, Molecular Biology and Pharmacology, having authored 33 papers that have together received 1.4k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (6 papers), Sphingolipid Metabolism and Signaling (6 papers), Synthetic Organic Chemistry Methods (5 papers), Carbohydrate Chemistry and Synthesis (5 papers), Click Chemistry and Applications (4 papers), Protein Degradation and Inhibitors (4 papers), Microbial Natural Products and Biosynthesis (3 papers) and RNA modifications and cancer (3 papers). The work is most often cited by research in Organic Chemistry (669 citations), Molecular Biology (938 citations) and Pharmaceutical Science (48 citations). Frédéric J. Zécri has collaborated with scholars based in Switzerland, United States and China. Frequent co-authors include Danilo Guerini, Florian Müllershausen, Klaus Seuwen, Andreas Billich, Simone Bonazzi, Anthony G. M. Barrett, Kaila A. Margrey, Joshua B. McManus, David A. Nicewicz and Susan M. Cramp. Their work appears in journals such as Journal of the American Chemical Society, Angewandte Chemie International Edition and Diabetes.

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