Frédéric J. Zécri

2.4k citations

33 papers · 1.4k indexed · h-index 19

Co-authors: Danilo Guerini Florian Müllershausen Klaus Seuwen Andreas Billich Simone Bonazzi Anthony G. M. Barrett Kaila A. Margrey Joshua B. McManus
Topics: Chemical Synthesis and Analysis (6 papers)Sphingolipid Metabolism and Signaling (6 papers)Synthetic Organic Chemistry Methods (5 papers)
Cited by: Organic Chemistry Molecular Biology Pharmaceutical Science
Journals: Journal of the American Chemical Society Angewandte Chemie International Edition Diabetes
Partner nations: Switzerland United States China

In The Last Decade

Frédéric J. Zécri

32 papers receiving 1.4k citations

Peers

Countries citing papers authored by Frédéric J. Zécri

Since Specialization

Citations

This map shows the geographic impact of Frédéric J. Zécri's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frédéric J. Zécri with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frédéric J. Zécri more than expected).

Fields of papers citing papers by Frédéric J. Zécri

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frédéric J. Zécri. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frédéric J. Zécri. The network helps show where Frédéric J. Zécri may publish in the future.

Co-authorship network of co-authors of Frédéric J. Zécri

This figure shows the co-authorship network connecting the top 25 collaborators of Frédéric J. Zécri. A scholar is included among the top collaborators of Frédéric J. Zécri based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frédéric J. Zécri. Frédéric J. Zécri is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Development of an FKBP12-recruiting chemical-induced proximity DNA-encoded library and its application to discover an autophagy potentiator 2025 ·Cell chemical biology ·Zher Yin Tan,(unknown),(unknown),(unknown),Michael Salcius,Bingqi Tong,Shuang Liu,Seungmin Hwang,Frédéric J. Zécri,Daniel B. Graham,Stuart L. Schreiber,Ramnik J. Xavier	6
2	Selectivity Profiling of Bromodomain PROTACs Using Chemical Inducers of Proximity DNA-Encoded Library Screening 2025 ·ACS Chemical Biology ·(unknown),Bingqi Tong,Zher Yin Tan,Antonin Tutter,(unknown),Patricia A. Horton,M.J. Romanowski,Frédéric J. Zécri,Stuart L. Schreiber,Shuang Liu	0
3	DNA-encoded library-enabled discovery of proximity-inducing small molecules 2023 ·Nature Chemical Biology ·(unknown),(unknown),(unknown),Antonin Tutter,Gregory A. Michaud,Matthias V. Westphal,Wei Shu,Xiaolei Ma,Zher Yin Tan,Connor W. Coley,Paul A. Clemons,Simone Bonazzi,Frédéric Berst,Karin Briner,Shuang Liu,Frédéric J. Zécri,Stuart L. Schreiber	41
4	Rational Screening for Cooperativity in Small-Molecule Inducers of Protein–Protein Associations 2023 ·Journal of the American Chemical Society ·Shuang Liu,Bingqi Tong,(unknown),J.M. Ostrem,Antonin Tutter,Bruce K. Hua,(unknown),Simone Bonazzi,Karin Briner,Frédéric Berst,Frédéric J. Zécri,Stuart L. Schreiber	35
5	Modular Synthesis of Cyclopropane‐Fused N‐Heterocycles Enabled by Underexplored Diazo Reagents 2022 ·Angewandte Chemie International Edition ·(unknown),Frédéric J. Zécri,Karin Briner,Stuart L. Schreiber	12
6	Successful Strategies for Mitigation of a Preclinical Signal for Phototoxicity in a DGAT1 Inhibitor 2019 ·ACS Medicinal Chemistry Letters ·Tyler Harrison,Daniel Bauer,(unknown),Xin Chen,(unknown),(unknown),Panos Hatsis,Qian Liu,(unknown),(unknown),(unknown),Frédéric J. Zécri,(unknown),Rui Zheng,(unknown),Ryan S. Streeper,Sejal Patel	6
7	3′-Modification stabilizes mRNA and increases translation in cells 2018 ·Bioorganic & Medicinal Chemistry Letters ·Christian M. Gampe,Amy C. Seila White,(unknown),Frédéric J. Zécri,John L. Diener	7
8	Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors 2017 ·ACS Medicinal Chemistry Letters ·Klemens Hoegenauer,Nicolas Soldermann,Frédéric J. Zécri,(unknown),(unknown),Romain M. Wolf,Nigel G. Cooke,Alexander B. Smith,Gregory J. Hollingworth,Joachim Blanz,Sascha Gutmann,Gabriele Rummel,Amanda Littlewood‐Evans,Christoph Burkhart	84
9	Medicinal Chemistry Profiling of Monocyclic 1,2‐Azaborines 2017 ·ChemMedChem ·Peng Zhao,David O. Nettleton,Rajeshri G. Karki,Frédéric J. Zécri,Shih‐Yuan Liu	97
10	Discovery of novel pyrrolidineoxy-substituted heteroaromatics as potent and selective PI3K delta inhibitors with improved physicochemical properties 2016 ·Bioorganic & Medicinal Chemistry Letters ·Klemens Hoegenauer,Nicolas Soldermann,(unknown),Gregory J. Hollingworth,Ian Lewis,(unknown),Alexander B. Smith,Romain M. Wolf,Rainer Wilcken,Dorothea Haasen,Christoph Burkhart,Frédéric J. Zécri	17
11	From Natural Product to the First Oral Treatment for Multiple Sclerosis: The Discovery of FTY720 (Gilenya™)? 2016 ·Current Opinion in Chemical Biology ·Frédéric J. Zécri	22
12	Discovery and Pharmacological Characterization of Novel Quinazoline-Based PI3K Delta-Selective Inhibitors 2016 ·ACS Medicinal Chemistry Letters ·Klemens Hoegenauer,Nicolas Soldermann,Frédéric Stauffer,Pascal Furet,(unknown),Alexander B. Smith,(unknown),Gregory J. Hollingworth,Ian Lewis,Sascha Gutmann,Gabriele Rummel,Mark Knapp,Romain M. Wolf,Joachim Blanz,Roland Feifel,Christoph Burkhart,Frédéric J. Zécri	49
13	Covalent Chemical 5′‐Functionalization of RNA with Diazo Reagents 2016 ·Angewandte Chemie International Edition ·Christian M. Gampe,(unknown),Frédéric J. Zécri	18
14	The design and implementation of a generic lipopeptide scanning platform to enable the identification of ‘locally acting’ agonists for the apelin receptor 2014 ·Bioorganic & Medicinal Chemistry Letters ·Stephen C. McKeown,Frédéric J. Zécri,(unknown),Andrew K.P. Taggart,(unknown),Christopher M. Adams,(unknown),Sokhom S. Pin	12
15	Absorption and Disposition of the Sphingosine 1-Phosphate Receptor Modulator Fingolimod (FTY720) in Healthy Volunteers: A Case of Xenobiotic Biotransformation Following Endogenous Metabolic Pathways 2010 ·Drug Metabolism and Disposition ·Markus Zollinger,Hans-Peter Gschwind,Yi Jin,(unknown),Frédéric J. Zécri,Stefan Hartmann	40
16	Pyrazole derived from (+)-3-carene; a novel potent, selective scaffold for sphingosine-1-phosphate (S1P1) receptor agonists 2009 ·Bioorganic & Medicinal Chemistry Letters ·Frédéric J. Zécri,Rainer Albert,Gregory A. Landrum,Klaus Hinterding,Nigel G. Cooke,Danilo Guerini,Markus Streiff,Christian Bruns,Barbara Nuesslein‐Hildesheim	6
17	Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors 2009 ·Nature Chemical Biology ·Florian Müllershausen,Frédéric J. Zécri,(unknown),Andreas Billich,Danilo Guerini,Klaus Seuwen	306
18	Stereocontrolled Synthesis of the Quinaldic Acid Macrocyclic System of Thiostrepton We thank Drs. D. H. Huang and G. Suizdak for NMR spectroscopic and mass spectrometric assistance, respectively, as well as Mike Sertic (University of California, San Diego) for experimental assistance. Financial support for this work was provided by The Skaggs Institute for Chemical Biology, the National Institutes of Health (USA), fellowships from The Skaggs Institute for Research (to M.Z. and F.Z.), and grants from Abbott, Amgen, Array Biopharma, Boehringer-Ingelheim, Glaxo, Hoffmann-LaRoche, DuPont, Merck, Novartis, Pfizer, and Schering Plough. 2002 ·Angewandte Chemie ·K. C. Nicolaou,Brian S. Safina,Christian Funke,Mark Zak,Frédéric J. Zécri	15
19	Chromatography-Free Synthesis of 1,2,4-Oxadiazoles Using ROMPGEL-Supported Acylating Reagents 2000 ·Combinatorial Chemistry & High Throughput Screening ·Amy Barrett,Susan M. Cramp,Richard S. Roberts,Frédéric J. Zécri	14
20	ROMPGEL Scavengers: A High-Loading Supported Anhydride for Sequestering Amines and Hydrazines 2000 ·Organic Letters ·Thomas Arnauld,Anthony G. M. Barrett,Susan M. Cramp,Richard S. Roberts,Frédéric J. Zécri	17

About Frédéric J. Zécri

Frédéric J. Zécri is a scholar working on Organic Chemistry, Molecular Biology and Pharmacology, having authored 33 papers that have together received 1.4k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (6 papers), Sphingolipid Metabolism and Signaling (6 papers) and Synthetic Organic Chemistry Methods (5 papers). The work is most often cited by research in Organic Chemistry (669 citations), Molecular Biology (938 citations) and Pharmaceutical Science (48 citations). Frédéric J. Zécri has collaborated with scholars based in Switzerland, United States and China. Frequent co-authors include Danilo Guerini, Florian Müllershausen, Klaus Seuwen, Andreas Billich, Simone Bonazzi, Anthony G. M. Barrett, Kaila A. Margrey, Joshua B. McManus, David A. Nicewicz and Susan M. Cramp. Their work appears in journals such as Journal of the American Chemical Society, Angewandte Chemie International Edition and Diabetes.

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