Patrick Maloney

4.8k citations

36 papers · 3.8k indexed · 2 hit papers · h-index 17

Impact in

Oncology top 1%
- Drug Transport and Resistance Mechanisms
Hepatology top 2%
- Liver Diseases and Immunity

Papers in ⓘ

Molecular Biology 19
- Receptor Mechanisms and Signaling 5
- Phenothiazines and Benzothiazines Synthesis and Activities 3
- Sexual Differentiation and Disorders 3
Cellular and Molecular Neuroscience 7
- Neuropeptides and Animal Physiology 4

Co-authors: Timothy M. Willson (5 shared papers)Linda B. Moore (2 shared papers)Stacey A. Jones (2 shared papers)Michael C. Lewis (2 shared papers)Joan G. Wilson (2 shared papers)Bryan Goodwin (2 shared papers)Michael A. Watson (1 shared paper)Matthew E. Roth (1 shared paper)
Journals: Journal of Medicinal Chemistry (8 papers)Bioorganic & Medicinal Chemistry Letters (5 papers)Methods (2 papers)ACS Chemical Biology (2 papers)Journal of Pharmacology and Experimental Therapeutics (1 paper)
Partner nations: United States Netherlands Japan

In The Last Decade

Patrick Maloney

34 papers receiving 3.7k citations

Hit Papers

align trajectories log scale

6α-Ethyl-Chenodeoxycholic Acid (6-ECDCA), a Potent and Selective FXR Agonist Endowed with Anticholestatic Activity 2002 · 617 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2002 Journal of Medicinal Chemistry
2000 Molecular Cell

Peers

Countries citing papers authored by Patrick Maloney

Since Specialization

Citations

This map shows the geographic impact of Patrick Maloney's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick Maloney with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick Maloney more than expected).

Fields of papers citing papers by Patrick Maloney

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick Maloney. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick Maloney. The network helps show where Patrick Maloney may publish in the future.

Co-authors

The 25 scholars most cited alongside Patrick Maloney, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Patrick Maloney Line = papers co-authored together Patrick Maloney links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 36 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis Molecular Cell ·Bryan Goodwin, Stacey A. Jones, Roger R. Price, Michael A. Watson, David D. McKee, Linda B. Moore, Cristin M. Galardi, Joan G. Wilson, Michael C. Lewis, Matthew E. Roth, Patrick Maloney, Timothy M. Willson, Steven A. Kliewer Hit paper breakdown →	2000	1598
2	6α-Ethyl-Chenodeoxycholic Acid (6-ECDCA), a Potent and Selective FXR Agonist Endowed with Anticholestatic Activity Journal of Medicinal Chemistry ·Roberto Pellicciari, Stefano Fiorucci, Emidio Camaioni, Carlo Clerici, Gabriele Costantino, Patrick Maloney, Antonio Morelli, Derek J. Parks, Timothy M. Willson Hit paper breakdown →	2002	617
3	Identification of a Chemical Tool for the Orphan Nuclear Receptor FXR Journal of Medicinal Chemistry ·Patrick Maloney, Derek J. Parks, Curt D. Haffner, Adam M. Fivush, Gyan Chandra, Kelli D. Plunket, Katrina L. Creech, Linda B. Moore, Joan G. Wilson, Michael C. Lewis, Stacey A. Jones, Timothy M. Willson	2000	464
4	Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ)—synthesis and biological activity Bioorganic & Medicinal Chemistry Letters ·Marcos L. Sznaidman, Curt D. Haffner, Patrick Maloney, Adam M. Fivush, Esther Y. Chao, Donna M. Goreham, Michael L. Sierra, Christelle LeGrumelec, H. Eric Xu, Valerie G. Montana, Millard H. Lambert, Timothy M. Willson, William R. Oliver, Daniel D. Sternbach	2003	272
5	β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors Cell ·Lauren M. Slosky, Yushi Bai, Krisztián Tóth, Caroline Ray, Lauren K. Rochelle, Alexandra Badea, Rahul Chandrasekhar, Vladimir M. Pogorelov, Dennis Abraham, Namratha Atluri, Satyamaheshwar Peddibhotla, Michael P. Hedrick, Paul Hershberger, Patrick Maloney, Hong Yuan, Zibo Li, William C. Wetsel, Anthony B. Pinkerton, Lawrence S Barak, Marc G. Caron	2020	94
6	Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120) Bioorganic & Medicinal Chemistry Letters ·Steven M. Sparks, Grace Chen, Jon L. Collins, Dana P. Danger, Steven T. Dock, Channa Jayawickreme, Stephen Jenkinson, Christopher P. Laudeman, M. Anthony Leesnitzer, Xi Liang, Patrick Maloney, David C. McCoy, David Moncol, Vincent Rash, Thomas J. Rimele, Padmaja Vulimiri, James M. Way, Sean Ross	2014	94
7	Bile Acids Enhance Low Density Lipoprotein Receptor Gene Expression via a MAPK Cascade-mediated Stabilization of mRNA Journal of Biological Chemistry ·Mayuko Nakahara, Hiroshi Fujii, Patrick Maloney, Makoto Shimizu, Ryuichiro Sato	2002	84
8	Identification of Small Molecule Agonists of the Orphan Nuclear Receptors Liver Receptor Homolog-1 and Steroidogenic Factor-1 Journal of Medicinal Chemistry ·Richard J. Whitby, Sally Dixon, Patrick Maloney, Philippe Delerive, Bryan Goodwin, Derek J. Parks, Timothy M. Willson	2006	75
9	3-Benzisothiazolylpiperazine Derivatives as Potential Atypical Antipsychotic Agents Journal of Medicinal Chemistry ·Harry Howard, John Lowe, Thomas Seeger, Patricia A. Seymour, Stevin H. Zorn, Patrick Maloney, Frank E. Ewing, Michael E. Newman, Anne W. Schmidt, Jerome S. Furman, Gwendolyn L. Robinson, Elisa R. Jackson, Celeste Johnson, Jean Morrone	1996	71
10	6-Azasteroids: Structure-Activity Relationships for Inhibition of Type 1 and 2 Human 5.alpha.-Reductase and Human Adrenal 3.beta.-Hydroxy-.DELTA.5-steroid Dehydrogenase/3-Keto-.DELTA.5-steroid Isomerase Journal of Medicinal Chemistry ·Stephen V. Frye, Curt D. Haffner, Patrick Maloney, Robert A. Mook, George F. Dorsey, Roger N. Hiner, C. M. CRIBBS, Thomas N. Wheeler, John A. Ray	1994	49
11	6-Azasteroids: potent dual inhibitors of human type 1 and 2 steroid 5.alpha.-reductase Journal of Medicinal Chemistry ·Stephen V. Frye, Curt D. Haffner, Patrick Maloney, Robert A. Mook, George F. Dorsey, Roger N. Hiner, Kenneth W. Batchelor, H. Neal Bramson, J. Darren Stuart	1993	46
12	ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse ACS Chemical Biology ·Larry S. Barak, Yushi Bai, Sean M. Peterson, Tama Evron, Nikhil M. Urs, Satyamaheshwar Peddibhotla, Michael P. Hedrick, Paul Hershberger, Patrick Maloney, Thomas D.Y. Chung, Ramona M. Rodriguiz, William C. Wetsel, James B. Thomas, Glen R. Hanson, Anthony B. Pinkerton, Marc G. Caron	2016	37
13	Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators Journal of Medicinal Chemistry ·Anthony B. Pinkerton, Satyamaheshwar Peddibhotla, Fusayo Yamamoto, Lauren M. Slosky, Yushi Bai, Patrick Maloney, Paul Hershberger, Michael P. Hedrick, Bekhi Falter, Robert Ardecky, Layton H. Smith, Thomas D.Y. Chung, Michael R. Jackson, Marc G. Caron, Lawrence S Barak	2019	32
14	Rare cancer cell analyzer for whole blood applications: Microcytometer cell counting and sorting subcircuits Methods ·Christy A. Lancaster, Mark Kokoris, M Nabavi, J. Clemmens, Patrick Maloney, J. Capadanno, J. Gerdes, C.F. Battrell	2005	27
15	Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress Journal of Pharmacology and Experimental Therapeutics ·R. Jason Kirby, Daniela Divlianska, Kanupriya Whig, Nadezda Bryan, Camilo J. Morfa, Ada Koo, Becky Hood, Kevin Nguyen, Patrick Maloney, Satayamaheshwar Peddibhotla, E. Hampton Sessions, Paul Hershberger, Layton H. Smith, Siobhan Malany	2017	21
16	A novel additive manufacturing compression overmolding process for hybrid metal polymer composite structures SHILAP Revista de lepidopterología ·Deepak Kumar Pokkalla, Ahmed Arabi Hassen, D. Nuttall, Nikolaos Tsiamis, Mitchell L. Rencheck, Vipin Kumar, Peeyush Nandwana, Chase Joslin, P. Blanchard, Sangram Tamhankar, Patrick Maloney, Vlastimil Kunc, Seokpum Kim	2023	17
17	Synthesis of a Library of 2-Alkyl-3-alkyloxy-2H-indazole-6-carboxamides Journal of Combinatorial Chemistry ·Aaron D. Mills, Patrick Maloney, Elsayed Hassanein, Makhluf J. Haddadin, Mark J. Kurth	2006	16
18	Discovery of small molecule antagonists of chemokine receptor CXCR6 that arrest tumor growth in SK-HEP-1 mouse xenografts as a model of hepatocellular carcinoma Bioorganic & Medicinal Chemistry Letters ·Satyamaheshwar Peddibhotla, Paul Hershberger, R. Jason Kirby, Eliot Sugarman, Patrick Maloney, E. Hampton Sessions, Daniela Divlianska, Camilo J. Morfa, David Terry, Anthony B. Pinkerton, Layton H. Smith, Siobhan Malany	2019	15
19	Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activators Bioorganic & Medicinal Chemistry Letters ·Anthony B. Pinkerton, E. Hampton Sessions, Paul Hershberger, Patrick Maloney, Satyamaheshwar Peddibhotla, Meghan Hopf, Eduard Sergienko, Chen-Ting Ma, Layton H. Smith, Michael R. Jackson, Jun Tanaka, Takashi Tsuji, Mayuko Akiu, Steven E. Cohen, Tsuyoshi Nakamura, Stephen J. Gardell	2021	15
20	Rare cancer cell analyzer for whole blood applications: Automated nucleic acid purification in a microfluidic disposable card Methods ·Mark Kokoris, M Nabavi, Christy A. Lancaster, J. Clemmens, Patrick Maloney, J. Capadanno, J. Gerdes, C.F. Battrell	2005	15

About Patrick Maloney

Patrick Maloney is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Oncology, Organic Chemistry and Surgery, having authored 36 papers that have together received 3.8k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (5 papers), Drug Transport and Resistance Mechanisms (5 papers), Neuropeptides and Animal Physiology (4 papers), Phenothiazines and Benzothiazines Synthesis and Activities (3 papers), Sexual Differentiation and Disorders (3 papers), Parasites and Host Interactions (3 papers), Cholesterol and Lipid Metabolism (3 papers) and Power System Optimization and Stability (2 papers). The work is most often cited by research in Oncology (2.1k citations), Hepatology (411 citations), Pharmacology (334 citations), Surgery (1.4k citations) and Epidemiology (869 citations). Patrick Maloney has collaborated with scholars based in United States, Netherlands and Japan. Frequent co-authors include Timothy M. Willson, Linda B. Moore, Stacey A. Jones, Michael C. Lewis, Joan G. Wilson, Bryan Goodwin, Michael A. Watson, Matthew E. Roth, David D. McKee and Cristin M. Galardi. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Methods, ACS Chemical Biology and Journal of Pharmacology and Experimental Therapeutics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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