Osamu Higuchi

5.5k total citations · 1 hit paper
86 papers, 4.3k citations indexed

About

Osamu Higuchi is a scholar working on Neurology, Molecular Biology and Surgery. According to data from OpenAlex, Osamu Higuchi has authored 86 papers receiving a total of 4.3k indexed citations (citations by other indexed papers that have themselves been cited), including 37 papers in Neurology, 20 papers in Molecular Biology and 17 papers in Surgery. Recurrent topics in Osamu Higuchi's work include Myasthenia Gravis and Thymoma (25 papers), Peripheral Neuropathies and Disorders (18 papers) and Autoimmune Neurological Disorders and Treatments (14 papers). Osamu Higuchi is often cited by papers focused on Myasthenia Gravis and Thymoma (25 papers), Peripheral Neuropathies and Disorders (18 papers) and Autoimmune Neurological Disorders and Treatments (14 papers). Osamu Higuchi collaborates with scholars based in Japan, United States and United Kingdom. Osamu Higuchi's co-authors include Kensaku Mizuno, Yuji Yamanashi, Kazumasa Ohashi, Neng Yang, Eisuke Nishida, Kyoko Nagata, Atsushi Wada, Kenji Kangawa, Masakatsu Motomura and Toshikazu Nakamura and has published in prestigious journals such as Nature, Science and Journal of Biological Chemistry.

In The Last Decade

Osamu Higuchi

81 papers receiving 4.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization

1998 1.1k citations Neng Yang, Osamu Higuchi et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Osamu Higuchi Japan	27	2.0k	1.1k	999	545	536	86	4.3k
Stefan Isenmann Germany	38	3.6k 1.8×	316 0.3×	716 0.7×	583 1.1×	1.3k 2.4×	125	6.1k
Chiara Collesi Italy	22	1.8k 0.9×	724 0.7×	223 0.2×	459 0.8×	356 0.7×	34	3.0k
Neil V. Morgan United Kingdom	42	3.0k 1.5×	469 0.4×	192 0.2×	407 0.7×	248 0.5×	109	5.7k
Debra Compton United States	12	5.8k 2.9×	753 0.7×	439 0.4×	527 1.0×	1.3k 2.3×	13	8.0k
Toshimitsu Suzuki Japan	36	1.7k 0.8×	268 0.2×	253 0.3×	628 1.2×	458 0.9×	201	4.3k
Tiziana Crepaldi Italy	28	1.5k 0.8×	276 0.3×	141 0.1×	499 0.9×	205 0.4×	70	2.9k
Carmen Ruiz de Almodóvar Germany	30	1.7k 0.9×	624 0.6×	219 0.2×	193 0.4×	583 1.1×	55	3.3k
Gregory Bix United States	34	1.6k 0.8×	1.1k 1.0×	371 0.4×	129 0.2×	447 0.8×	114	3.7k
C.D. Dijkstra Netherlands	26	986 0.5×	207 0.2×	248 0.2×	378 0.7×	395 0.7×	53	4.3k
Atsushi Watanabe Japan	29	1.1k 0.6×	414 0.4×	221 0.2×	314 0.6×	186 0.3×	137	3.0k

Countries citing papers authored by Osamu Higuchi

Since Specialization

Citations

This map shows the geographic impact of Osamu Higuchi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Osamu Higuchi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Osamu Higuchi more than expected).

Fields of papers citing papers by Osamu Higuchi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Osamu Higuchi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Osamu Higuchi. The network helps show where Osamu Higuchi may publish in the future.

Co-authorship network of co-authors of Osamu Higuchi

This figure shows the co-authorship network connecting the top 25 collaborators of Osamu Higuchi. A scholar is included among the top collaborators of Osamu Higuchi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Osamu Higuchi. Osamu Higuchi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Nakane, Shunya, Akihiro Mukaino, Osamu Higuchi, et al.. (2024). The Presence of Ganglionic Acetylcholine Receptor Antibodies in Sera from Patients with Functional Gastrointestinal Disorders: A Preliminary Study. Journal of Personalized Medicine. 14(5). 485–485.

Ishihara, Shoichiro, et al.. (2024). Unusual Presentation of Double-seronegative Myasthenia Gravis with Positive Anti-LRP4 Antibody: Diagnostic Utility of a Videofluoroscopic Swallowing Study. Internal Medicine. 64(2). 307–311. 1 indexed citations

Yamakawa, Makoto, Ichiro Kuki, Akihiro Mukaino, et al.. (2021). gAChR antibodies in children and adolescents with acquired autoimmune dysautonomia in Japan. Annals of Clinical and Translational Neurology. 8(4). 790–799. 4 indexed citations

Higuchi, Osamu, Yasuhiro Maeda, Akihiro Mukaino, et al.. (2020). Anti-Kir4.1 Antibodies in Multiple Sclerosis: Specificity and Pathogenicity. International Journal of Molecular Sciences. 21(24). 9632–9632. 9 indexed citations

Nakane, Shunya, Masataka Umeda, Shin‐ya Kawashiri, et al.. (2020). Detecting gastrointestinal manifestations in patients with systemic sclerosis using anti-gAChR antibodies. Arthritis Research & Therapy. 22(1). 32–32. 15 indexed citations

Mukaino, Akihiro, Koutaro Takamatsu, Hiroto Tsuboi, et al.. (2020). Ganglionic Acetylcholine Receptor Antibodies and Autonomic Dysfunction in Autoimmune Rheumatic Diseases. International Journal of Molecular Sciences. 21(4). 1332–1332. 13 indexed citations

Nakane, Shunya, Osamu Higuchi, Koutaro Takamatsu, et al.. (2019). Lipoprotein receptor‐related protein 4 autoantibodies in myasthenia gravis: Where are we and where are we going?. Clinical and Experimental Neuroimmunology. 10(2). 79–84.

Mukaino, Akihiro, Hitomi Minami, Hajime Isomoto, et al.. (2018). Anti-ganglionic AChR antibodies in Japanese patients with motility disorders. Journal of Gastroenterology. 53(12). 1227–1240. 22 indexed citations

Nakane, Shunya, Osamu Higuchi, Yukihiro Hamada, et al.. (2016). Ganglionic acetylcholine receptor autoantibodies in patients with Guillain-Barré syndrome. Journal of Neuroimmunology. 295-296. 54–59. 8 indexed citations

10.

Higuchi, Osamu, Motonori Okabe, Toshiko Yoshida, et al.. (2012). Stemness of Human Wharton's Jelly Mesenchymal Cells Is Maintained by Floating Cultivation. Cellular Reprogramming. 14(5). 448–455. 15 indexed citations

11.

Higuchi, Osamu, et al.. (2012). Mothers’ knowledge about foreign body aspiration in young children. International Journal of Pediatric Otorhinolaryngology. 77(1). 41–44. 35 indexed citations

12.

Ito, Yasunori, Yuichi Adachi, Toshiko Itazawa, et al.. (2011). Association between the Results of the Childhood Asthma Control Test and Objective Parameters in Asthmatic Children. Journal of Asthma. 48(10). 1076–1080. 24 indexed citations

13.

Beeson, David, Osamu Higuchi, Jackie Palace, et al.. (2006). Dok-7 Mutations Underlie a Neuromuscular Junction Synaptopathy. Science. 313(5795). 1975–1978. 201 indexed citations

14.

Higuchi, Osamu, et al.. (2006). Mutations in dok-7 underlie a congenital myasthenic syndrome with a (sic)Limb girdle broken vertical bar pattern of muscle weakness.. Annals of Neurology. 60. 640–640. 1 indexed citations

15.

Honma, Miyuki, Osamu Higuchi, Masaki Shirakata, et al.. (2006). Dok‐3 sequesters Grb2 and inhibits the Ras‐Erk pathway downstream of protein‐tyrosine kinases. Genes to Cells. 11(2). 143–151. 33 indexed citations

16.

Otera, Hidenori, Kanji Okumoto, Maki Nishimura, et al.. (1998). Peroxisome Targeting Signal Type 1 (PTS1) Receptor Is Involved in Import of Both PTS1 and PTS2: Studies with PEX5 -Defective CHO Cell Mutants. Molecular and Cellular Biology. 18(1). 388–399. 178 indexed citations

17.

Yang, Neng, Osamu Higuchi, Kazumasa Ohashi, et al.. (1998). Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature. 393(6687). 809–812. 1074 indexed citations breakdown →

18.

Higuchi, Osamu, et al.. (1996). Suppression of fibroblast cell growth by overexpression of LIM‐kinase 1. FEBS Letters. 396(1). 81–86. 16 indexed citations

19.

Okano, Ichiro, et al.. (1996). Self‐association of LIM‐kinase 1 mediated by the interaction between an N‐terminal LIM domain and a C‐terminal kinase domain. FEBS Letters. 399(1-2). 117–121. 35 indexed citations

20.

Kuroda, Shun’ichi, Chiharu Tokunaga, Yoshimoto Kiyohara, et al.. (1996). Protein-Protein Interaction of Zinc Finger LIM Domains with Protein Kinase C. Journal of Biological Chemistry. 271(49). 31029–31032. 229 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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