Tetsu Akiyama

24.4k total citations · 3 hit papers
264 papers, 20.0k citations indexed

About

Tetsu Akiyama is a scholar working on Molecular Biology, Oncology and Cell Biology. According to data from OpenAlex, Tetsu Akiyama has authored 264 papers receiving a total of 20.0k indexed citations (citations by other indexed papers that have themselves been cited), including 220 papers in Molecular Biology, 57 papers in Oncology and 45 papers in Cell Biology. Recurrent topics in Tetsu Akiyama's work include Wnt/β-catenin signaling in development and cancer (64 papers), Cancer-related gene regulation (39 papers) and Glycosylation and Glycoproteins Research (30 papers). Tetsu Akiyama is often cited by papers focused on Wnt/β-catenin signaling in development and cancer (64 papers), Cancer-related gene regulation (39 papers) and Glycosylation and Glycoproteins Research (30 papers). Tetsu Akiyama collaborates with scholars based in Japan, United States and Russia. Tetsu Akiyama's co-authors include Hiroshi Ogawara, Kumao Toyoshima, Shun‐ichi Watanabe, Yuko Fukami, Shizue Nakagawa, Masabumi Shibuya, Junko Ishida, Yoshihiro Kawasaki, Tadashi Yamamoto and Tadashi Yamamoto and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Tetsu Akiyama

262 papers receiving 19.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Genistein, a specific inhibitor of tyrosine-specific protein kinases.

1987 3.3k citations Tetsu Akiyama, Hiroshi Ogawara et al. profile →
Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor

1986 1.1k citations Tadashi Yamamoto, Tetsu Akiyama et al. profile →
The Product of the Human c- erb B-2 Gene: a 185-Kilodalton Glycoprotein with Tyrosine Kinase Activity

1986 679 citations Tetsu Akiyama, Hiroshi Ogawara et al. profile →

Peers

Tetsu Akiyama

ONCOL

PFM

GENET

Tadashi Yamamoto Japan

Yoshihide Tsujimoto Japan

Rony Seger Israel

Masabumi Shibuya Japan

Ulf R. Rapp Germany

Jian Yu United States

Stanisław Krajewski United States

Keiko Nakayama Japan

Rolf Müller Germany

Masahiko Hibi Japan

Tadashi Yamamoto Japan

Tetsu Akiyama

13.2k ×1.0

5.0k ×1.1

ONCOL

2.8k ×0.9

1.2k ×0.5

PFM

2.0k ×0.9

GENET

Citations per year, relative to Tetsu Akiyama Tetsu Akiyama (= 1×) peers Tadashi Yamamoto

Countries citing papers authored by Tetsu Akiyama

Since Specialization

Citations

This map shows the geographic impact of Tetsu Akiyama's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tetsu Akiyama with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tetsu Akiyama more than expected).

Fields of papers citing papers by Tetsu Akiyama

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tetsu Akiyama. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tetsu Akiyama. The network helps show where Tetsu Akiyama may publish in the future.

Co-authorship network of co-authors of Tetsu Akiyama

This figure shows the co-authorship network connecting the top 25 collaborators of Tetsu Akiyama. A scholar is included among the top collaborators of Tetsu Akiyama based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tetsu Akiyama. Tetsu Akiyama is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kojima, Takuya, et al.. (2025). Exosome-like nanovesicles from Peucedanum Japonicum directly regulate inflammatory cytokines via small RNAs. Scientific Reports. 15(1). 27424–27424. 2 indexed citations

Taniue, Kenzui, Tomoatsu Hayashi, Yasuko Takeda, et al.. (2023). LncRNA ZNNT1 induces p53 degradation by interfering with the interaction between p53 and the SART3-USP15 complex. PNAS Nexus. 2(7). pgad220–pgad220. 4 indexed citations

Hayashi, Tomoatsu, Ai Yamada, Naomi Shimizu, et al.. (2022). CRISPR/Cas9 Screening for Identification of Genes Required for the Growth of Ovarian Clear Cell Carcinoma Cells. Current Issues in Molecular Biology. 44(4). 1587–1596.

Hayashi, Tomoatsu, Naomi Shimizu, Ai Yamada, et al.. (2022). PHOSPHATE exporter XPR1/SLC53A1 is required for the tumorigenicity of epithelial ovarian cancer. Cancer Science. 113(6). 2034–2043. 18 indexed citations

Nakajima, Natsu, Tomoatsu Hayashi, Katsunori Fujiki, et al.. (2021). Codependency and mutual exclusivity for gene community detection from sparse single-cell transcriptome data. Nucleic Acids Research. 49(18). e104–e104. 5 indexed citations

Morimoto, Masafumi, et al.. (2020). Dental metal hypersensitivity in patients with psoriasis vulgaris: A case‐control study using an in vitro quantitative sensitivity test. Health Science Reports. 4(1). e223–e223. 2 indexed citations

Morimoto, Masafumi, et al.. (2019). Higher incidence of zinc and nickel hypersensitivity in patients with irritable bowel syndrome. Immunity Inflammation and Disease. 7(4). 304–307. 6 indexed citations

Tanaka, M., Naoyuki Sotta, Yusuke Yamazumi, et al.. (2016). The Minimum Open Reading Frame, AUG-Stop, Induces Boron-Dependent Ribosome Stalling and mRNA Degradation. The Plant Cell. 28(11). 2830–2849. 101 indexed citations

Ohwada, Susumu, Shinji Sakurai, Ichiro Sakamoto, et al.. (2008). Prognostic significance of BMP and activin membranebound inhibitor in colorectal cancer. World Journal of Gastroenterology. 14(31). 4880–4880. 27 indexed citations

10.

Torisu, Yuichi, Akira Watanabe, Aya Nonaka, et al.. (2008). Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by β‐catenin/TCF. Cancer Science. 99(6). 1139–1146. 46 indexed citations

11.

Nasu‐Nishimura, Yukiko, Tomoatsu Hayashi, Toshio Okabe, et al.. (2006). Role of the Rho GTPase‐activating protein RICS in neurite outgrowth. Genes to Cells. 11(6). 607–614. 42 indexed citations

12.

Matsuura, Ken, et al.. (2006). The tumor suppressor LKB1 induces p21 expression in collaboration with LMO4, GATA-6, and Ldb1. Biochemical and Biophysical Research Communications. 343(4). 1186–1190. 38 indexed citations

13.

Higuchi, Osamu, et al.. (1996). Suppression of fibroblast cell growth by overexpression of LIM‐kinase 1. FEBS Letters. 396(1). 81–86. 16 indexed citations

14.

Hosono, Makoto, Tsuneo Saga, Harumi Sakahara, et al.. (1993). Construction of Immunoradiometric Assay for Circulating c‐erbB‐2 Protooncogene Product in Advanced Breast Cancer Patients. Japanese Journal of Cancer Research. 84(2). 147–152. 13 indexed citations

15.

Akiyama, Tetsu & Hiroshi Ogawara. (1991). [30] Use and specificity of genistein as inhibitor of protein-tyrosine kinases. Methods in enzymology on CD-ROM/Methods in enzymology. 201. 362–370. 375 indexed citations

16.

Akiyama, Tetsu, Satoru Matsuda, Yoshiharu Namba, et al.. (1991). The transforming potential of the c-erbB-2 protein is regulated by its autophosphorylation at the carboxyl-terminal domain.. Molecular and Cellular Biology. 11(2). 833–842. 110 indexed citations

17.

Saga, Tsuneo, Keigo Endo, Tetsu Akiyama, et al.. (1991). Scintigraphic detection of overexpressed c-erbB-2 protooncogene products by a class-switched murine anti-c-erbB-2 protein monoclonal antibody.. PubMed. 51(3). 990–4. 27 indexed citations

18.

Akiyama, Tetsu, et al.. (1991). The Transforming Potential of the c- erbB -2 Protein Is Regulated by Its Autophosphorylation at the Carboxyl-Terminal Domain. Molecular and Cellular Biology. 11(2). 833–842. 31 indexed citations

19.

Mori, Shigeo, Yasuyoshi Mori, Taketo Mukaiyama, et al.. (1990). In vitro and in vivo Release of Soluble erbB‐2 Protein from Human Carcinoma Cells. Japanese Journal of Cancer Research. 81(5). 489–494. 82 indexed citations

20.

Ogawara, Hiroshi, et al.. (1987). A SPECIFIC INHIBITOR FOR TYROSINE PROTEIN KINASE. Journal of Pharmacobio-Dynamics. 10(2). 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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