Nieske Brouwer

6.5k total citations · 3 hit papers
64 papers, 4.4k citations indexed

About

Nieske Brouwer is a scholar working on Neurology, Immunology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Nieske Brouwer has authored 64 papers receiving a total of 4.4k indexed citations (citations by other indexed papers that have themselves been cited), including 40 papers in Neurology, 30 papers in Immunology and 19 papers in Cellular and Molecular Neuroscience. Recurrent topics in Nieske Brouwer's work include Neuroinflammation and Neurodegeneration Mechanisms (38 papers), Immune cells in cancer (17 papers) and Immune Response and Inflammation (14 papers). Nieske Brouwer is often cited by papers focused on Neuroinflammation and Neurodegeneration Mechanisms (38 papers), Immune cells in cancer (17 papers) and Immune Response and Inflammation (14 papers). Nieske Brouwer collaborates with scholars based in Netherlands, Germany and Denmark. Nieske Brouwer's co-authors include Bart J. L. Eggen, Knut Biber, Hendrikus Boddeke, Erik Boddeke, J.C.V.M. Copray, Thomas Möller, Inge R. Holtman, Jonathan Vinet, W. Schaafsma and Divya Raj and has published in prestigious journals such as Science, Journal of Neuroscience and Nature Neuroscience.

In The Last Decade

Nieske Brouwer

62 papers receiving 4.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Transcriptomic analysis of purified human cortical microglia reveals age-associated changes

2017 510 citations Thais Fernanda de Almeida Galatro, Inge R. Holtman et al. Nature Neuroscience profile →
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis

2015 437 citations Inge R. Holtman, Divya Raj et al. Acta Neuropathologica Communications profile →
Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease

2021 207 citations Emma Gerrits, Nieske Brouwer et al. Acta Neuropathologica profile →

Peers

Countries citing papers authored by Nieske Brouwer

Since Specialization

Citations

This map shows the geographic impact of Nieske Brouwer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nieske Brouwer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nieske Brouwer more than expected).

Fields of papers citing papers by Nieske Brouwer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nieske Brouwer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nieske Brouwer. The network helps show where Nieske Brouwer may publish in the future.

Co-authorship network of co-authors of Nieske Brouwer

This figure shows the co-authorship network connecting the top 25 collaborators of Nieske Brouwer. A scholar is included among the top collaborators of Nieske Brouwer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nieske Brouwer. Nieske Brouwer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Microglia endotoxin tolerance is retained after enforced repopulation 2025 ·Brain Behavior and Immunity ·(unknown), (unknown), (unknown), Nieske Brouwer, Inge R. Holtman, Susanne M. Kooistra, Bart J. L. Eggen	0
2	Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA sequencing of human cerebral cortex 2022 ·Nature Neuroscience ·Emma Gerrits, Lucia Giannini, Nieske Brouwer, Shamiram Melhem, Danielle Seilhean, Isabelle Le Ber, (unknown), Alwin Kamermans, Gijs Kooij, Helga E. de Vries, Erik Boddeke, Harro Seelaar, John C. van Swieten, Bart J. L. Eggen	43
3	Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matter 2022 ·Acta Neuropathologica Communications ·(unknown), Emma Gerrits, Nieske Brouwer, Qiong Jiang, Laura Kracht, Michel Meijer, Erik Nutma, Regina Peferoen‐Baert, (unknown), Evelyn M. Wesseling, (unknown), Hans‐Joachim Gabius, Sandra Amor, Bart J. L. Eggen, Susanne M. Kooistra	41
4	Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease breakdown → 2021 ·Acta Neuropathologica ·Emma Gerrits, Nieske Brouwer, Susanne M. Kooistra, Maya E. Woodbury, Yannick Vermeiren, (unknown), Jan Mulder, Markus P. Kummer, Thomas Möller, Knut Biber, Wilfred F.A. den Dunnen, Peter Paul De Deyn, Bart J. L. Eggen, Erik Boddeke	207
5	Regionally diverse astrocyte subtypes and their heterogeneous response to EAE 2020 ·Glia ·Malte Borggrewe, (unknown), Ilia D. Vainchtein, Nieske Brouwer, Evelyn M. Wesseling, Jon D. Laman, Bart J. L. Eggen, Susanne M. Kooistra, Erik Boddeke	32
6	Human fetal microglia acquire homeostatic immune-sensing properties early in development 2020 ·Science ·Laura Kracht, Malte Borggrewe, (unknown), Nieske Brouwer, Susana M. Chuva de Sousa Lopes, Jon D. Laman, Sicco A. Scherjon, Jelmer R. Prins, Susanne M. Kooistra, Bart J. L. Eggen	127
7	Profiling Microglia From Alzheimer’s Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue 2020 ·Frontiers in Molecular Neuroscience ·(unknown), Qiong Jiang, Laura Kracht, Emma Gerrits, Marissa L. Dubbelaar, (unknown), Nieske Brouwer, Elly M. Hol, Jinte Middeldorp, (unknown), Maya E. Woodbury, Astrid Wachter, Simon Xi, Thomas Möller, Knut Biber, Susanne M. Kooistra, Erik Boddeke, Bart J. L. Eggen	51
8	Maternal inflammation induces immune activation of fetal microglia and leads to disrupted microglia immune responses, behavior, and learning performance in adulthood 2017 ·Neurobiology of Disease ·W. Schaafsma, Laura Bozal‐Basterra, Sabrina Jacobs, Nieske Brouwer, Peter Meerlo, Anne Schaafsma, Erik Boddeke, Bart J. L. Eggen	99
9	Transcriptomic analysis of purified human cortical microglia reveals age-associated changes breakdown → 2017 ·Nature Neuroscience ·Thais Fernanda de Almeida Galatro, Inge R. Holtman, Antônio Marcondes Lerário, Ilia D. Vainchtein, Nieske Brouwer, Paula R. Sola, Mariana Matera Veras, (unknown), Renata Elaine Paraízo Leite, Thomas Möller, Paul D. Wes, Mari Cleide Sogayar, Jon D. Laman, Wilfred F.A. den Dunnen, Carlos Pasqualucci, Sueli Mieko Oba‐Shinjo, Erik Boddeke, Suely Kazue Nagahashi Marie, Bart J. L. Eggen	510
10	Telomere shortening leads to an acceleration of synucleinopathy and impaired microglia response in a genetic mouse model 2016 ·Acta Neuropathologica Communications ·Annika Scheffold, Inge R. Holtman, Sandra Dieni, Nieske Brouwer, Sarah–Fee Katz, Billy Michael Chelliah Jebaraj, Philipp J. Kahle, Bastian Hengerer, André Lechel, Stephan Stilgenbauer, Erik Boddeke, Bart J. L. Eggen, K. Lenhard Rudolph, Knut Biber	41
11	Glia Open Access Database (GOAD): A comprehensive gene expression encyclopedia of glia cells in health and disease 2015 ·Data Archiving and Networked Services (DANS) ·(unknown), Ilia D. Vainchtein, (unknown), Inge R. Holtman, Bart J. L. Eggen, (unknown), (unknown), Nieske Brouwer, (unknown), Michiel Noback	1
12	Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis breakdown → 2015 ·Acta Neuropathologica Communications ·Inge R. Holtman, Divya Raj, Jeremy A. Miller, W. Schaafsma, Zhuoran Yin, Nieske Brouwer, Paul D. Wes, Thomas Möller, Marie Orre, Willem Kamphuis, Elly M. Hol, Erik Boddeke, Bart J. L. Eggen	437
13	Priming of microglia in a DNA-repair deficient model of accelerated aging 2014 ·Neurobiology of Aging ·Divya Raj, Dick Jaarsma, Inge R. Holtman, Marta Olah, Filipa M. Ferreira, W. Schaafsma, Nieske Brouwer, Michel Meijer, Monique C. de Waard, Ingrid van der Pluijm, Renata M. C. Brandt, Karim L. Kreft, Jon D. Laman, Gerald de Haan, Knut Biber, Jan H.J. Hoeijmakers, Bart J. L. Eggen, Hendrikus Boddeke	101
14	Neuroprotective function for ramified microglia in hippocampal excitotoxicity 2012 ·Journal of Neuroinflammation ·Jonathan Vinet, Hilmar R. J. van Weering, Annette Heinrich, Roland E. Kälin, Anja Wegner, Nieske Brouwer, Frank L. Heppner, Nico van Rooijen, Hendrikus Boddeke, Knut Biber	223
15	An optimized protocol for the acute isolation of human microglia from autopsy brain samples 2011 ·Glia ·Marta Olah, Divya Raj, Nieske Brouwer, Alexander H. De Haas, Bart J. L. Eggen, Wilfred F.A. den Dunnen, Knut Biber, Hendrikus Boddeke	59
16	Expression of CXCL4 in microgliain vitroandin vivoand its possible signaling through CXCR3 2008 ·Journal of Neurochemistry ·Eiko K. de Jong, Alexander H. De Haas, Nieske Brouwer, Hilmar R. J. van Weering, (unknown), Ingo Bechmann, Pierre Pratley, Evelyn M. Wesseling, Hendrikus Boddeke, Knut Biber	71
17	The postnatal developmental expression pattern of urocortin in the rat olivocerebellar system 2004 ·The Journal of Comparative Neurology ·Jerome D. Swinny, D. Kalicharan, Nieske Brouwer, Knut Biber, Fuxin Shi, Albert Gramsbergen, J.J.L. van der Want	7
18	Neuronal SLC (CCL21) Expression: Implications for the Neuron-Microglial Signaling System 2002 ·PubMed ·Knut Biber, Angelika Rappert, Helmut Kettenmann, Nieske Brouwer, Sjef Copray, H. W. G. M. Boddeke	7
19	Neurotrophin-3 mRNA expression in rat intrafusal muscle fibres after denervation and reinnervation 1997 ·Neuroscience Letters ·J.C.V.M. Copray, Nieske Brouwer	25
20	Localization of dopamine D2 receptor mRNA with non-radioactive in situ hybridization histochemistry 1992 ·Neuroscience Letters ·Nieske Brouwer, (unknown), Marcel H.J. Ruiters, (unknown), Gert J. Ter Horst	21

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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