Nico Scheer

3.1k citations

37 papers · 2.3k indexed · 1 hit paper · h-index 21

Impact in

Pharmacology top 0.5%
- Pharmacogenetics and Drug Metabolism
Cell Biology top 2%
- Zebrafish Biomedical Research Applications

Papers in ⓘ

Pharmacology 21
- Pharmacogenetics and Drug Metabolism 21
Oncology 17
- Drug Transport and Resistance Mechanisms 16

Co-authors: José A. Campos‐Ortega (6 shared papers)C. Roland Wolf (19 shared papers)Nathan D. Lawson (1 shared paper)Ajay Chitnis (1 shared paper)Van N. Pham (1 shared paper)Brant M. Weinstein (1 shared paper)Cheol‐Hee Kim (1 shared paper)Anja Rode (11 shared papers)
Journals: Drug Metabolism and Disposition (9 papers)Molecular Pharmacology (4 papers)Drug Metabolism Reviews (3 papers)Development (3 papers)Drug Discovery Today (2 papers)
Partner nations: United Kingdom Germany United States

In The Last Decade

Nico Scheer

35 papers receiving 2.3k citations

Hit Papers

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Notch signaling is required for arterial-venous differentiation during embryonic vascular development 2001 · 698 citations

Peers

Countries citing papers authored by Nico Scheer

Since Specialization

Citations

This map shows the geographic impact of Nico Scheer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nico Scheer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nico Scheer more than expected).

Fields of papers citing papers by Nico Scheer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nico Scheer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nico Scheer. The network helps show where Nico Scheer may publish in the future.

Co-authors

The 25 scholars most cited alongside Nico Scheer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Nico Scheer Line = papers co-authored together Nico Scheer links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 37 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Notch signaling is required for arterial-venous differentiation during embryonic vascular development Development ·Nathan D. Lawson, Nico Scheer, Van N. Pham, Cheol‐Hee Kim, Ajay Chitnis, José A. Campos‐Ortega, Brant M. Weinstein Hit paper breakdown →	2001	698
2	Use of the Gal4-UAS technique for targeted gene expression in the zebrafish Mechanisms of Development ·Nico Scheer, José A. Campos‐Ortega	1999	319
3	An instructive function for Notch in promoting gliogenesis in the zebrafish retina Development ·Nico Scheer, Anne Karoline Groth, Stefan Hans, José A. Campos‐Ortega	2001	206
4	Human Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) Support the Hypertrophic but not the Hyperplastic Response to the Murine Nongenotoxic Hepatocarcinogens Phenobarbital and Chlordane In Vivo Toxicological Sciences ·Jillian Ross, Simon Plummer, Anja Rode, Nico Scheer, Conrad C. Bower, Ortwin Vogel, Colin J. Henderson, C. Roland Wolf, Clifford R. Elcombe	2010	117
5	A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response Journal of Clinical Investigation ·Nico Scheer, Jillian Ross, Anja Rode, Branko Zevnik, Niehaves Sandra, Nicole Faust, C. Roland Wolf	2008	112
6	PXR and CAR: Nuclear Receptors which Play a Pivotal Role in Drug Disposition and Chemical Toxicity Drug Metabolism Reviews ·Lesley A. Stanley, Brian C. Horsburgh, Jillian Ross, Nico Scheer, C. Roland Wolf	2006	109
7	Quantitative Prediction of Human Pregnane X Receptor and Cytochrome P450 3A4 Mediated Drug-Drug Interaction in a Novel Multiple Humanized Mouse Line Molecular Pharmacology ·Maki Hasegawa, Yury Kapelyukh, Harunobu Tahara, Jost Seibler, Anja Rode, Sylvia Krueger, Dongtao N. Lee, C. Roland Wolf, Nico Scheer	2011	71
8	A quantitative analysis of the kinetics of Gal4 activator and effector gene expression in the zebrafish Mechanisms of Development ·Nico Scheer, Iris Riedl, James T. Warren, John Y. Kuwada, José A. Campos‐Ortega	2002	66
9	A comparison between genetically humanized and chimeric liver humanized mouse models for studies in drug metabolism and toxicity Drug Discovery Today ·Nico Scheer, Ian D. Wilson	2015	63
10	her3, a zebrafish member of thehairy-E(spl)family, is repressed by Notch signalling Development ·Stefan Hans, Nico Scheer, Iris Riedl, Elisabeth v. Weizsäcker, Patrick Blader, José A. Campos‐Ortega	2004	52
11	Modeling Human Cytochrome P450 2D6 Metabolism and Drug-Drug Interaction by a Novel Panel of Knockout and Humanized Mouse Lines Molecular Pharmacology ·Nico Scheer, Yury Kapelyukh, Jillian McEwan, Vincent Beuger, Lesley A. Stanley, Anja Rode, C. Roland Wolf	2011	45
12	Generation and Characterization of Novel Cytochrome P450 Cyp2c Gene Cluster Knockout and CYP2C9 Humanized Mouse Lines Molecular Pharmacology ·Nico Scheer, Yury Kapelyukh, Lynsey R. Chatham, Anja Rode, Sandra Buechel, C. Roland Wolf	2012	42
13	Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice Drug Metabolism and Disposition ·Yury Kapelyukh, Colin J. Henderson, Nico Scheer, Anja Rode, C. Roland Wolf	2019	38
14	In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice Drug Metabolism and Disposition ·Nico Scheer, Jillian Ross, Yury Kapelyukh, Anja Rode, C. Roland Wolf	2010	36
15	Genetically humanized mouse models of drug metabolizing enzymes and transporters and their applications Xenobiotica ·Nico Scheer, C. Roland Wolf	2013	35
16	Asymmetric localization of Numb:EGFP in dividing neuroepithelial cells during neurulation in Danio rerio Developmental Dynamics ·Alexander M. Reugels, Barbara Boggetti, Nico Scheer, José A. Campos‐Ortega	2006	34
17	Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins Drug Metabolism and Disposition ·Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loïc Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A.B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel, Nico Scheer	2014	30
18	Cytochrome b5 Is a Major Determinant of Human Cytochrome P450 CYP2D6 and CYP3A4 Activity In Vivo Molecular Pharmacology ·Colin J. Henderson, Lesley A. McLaughlin, Nico Scheer, Lesley A. Stanley, C. Roland Wolf	2015	30
19	An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials Drug Metabolism and Disposition ·Colin J. Henderson, Yury Kapelyukh, Nico Scheer, Anja Rode, AW. McLaren, A. Kenneth MacLeod, De‐Chen Lin, J. Wright, Lesley A. Stanley, C. Roland Wolf	2019	29
20	Generation and utility of genetically humanized mouse models Drug Discovery Today ·Nico Scheer, M. L. Snaith, C. Roland Wolf, Jost Seibler	2013	26

About Nico Scheer

Nico Scheer is a scholar working on Pharmacology, Oncology, Molecular Biology, Endocrinology, Diabetes and Metabolism and Genetics, having authored 37 papers that have together received 2.3k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (21 papers), Drug Transport and Resistance Mechanisms (16 papers), Hormonal Regulation and Hypertension (7 papers), Eicosanoids and Hypertension Pharmacology (5 papers), Receptor Mechanisms and Signaling (4 papers), Zebrafish Biomedical Research Applications (4 papers), Animal Genetics and Reproduction (3 papers) and Pharmacological Effects and Toxicity Studies (3 papers). The work is most often cited by research in Pharmacology (552 citations), Cell Biology (702 citations), Developmental Neuroscience (123 citations), Molecular Biology (1.4k citations) and Biochemistry (117 citations). Nico Scheer has collaborated with scholars based in United Kingdom, Germany and United States. Frequent co-authors include José A. Campos‐Ortega, C. Roland Wolf, Nathan D. Lawson, Ajay Chitnis, Van N. Pham, Brant M. Weinstein, Cheol‐Hee Kim, Anja Rode, Jillian Ross and Stefan Hans. Their work appears in journals such as Drug Metabolism and Disposition, Molecular Pharmacology, Drug Metabolism Reviews, Development and Drug Discovery Today.

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