Colin J. Henderson

10.9k citations

166 papers · 8.6k indexed · 3 hit papers · h-index 45

Pharmacology top 0.05%
- Pharmacogenetics and Drug Metabolism 76
- Drug-Induced Hepatotoxicity and Protection 15
Biochemistry top 0.5%
- Eicosanoids and Hypertension Pharmacology 11
Molecular Biology top 1%
- Genomics, phytochemicals, and oxidative stress 32
- Glutathione Transferases and Polymorphisms 31
Oncology top 1%
- Drug Transport and Resistance Mechanisms 41
Biological Psychiatry top 2%
Genetics
- Estrogen and related hormone effects 13
Cancer Research
- Carcinogens and Genotoxicity Assessment 12

Co-authors: C. Roland Wolf John D. Hayes Masayuki Yamamoto Michael McMahon Simon A. Chanas Ken Itoh Lesley I. McLellan Aileen McLaren
Cited by: Pharmacology Biochemistry Molecular Biology
Journals: Nature (1 paper)Proceedings of the National Academy of Sciences (7 papers)Journal of Biological Chemistry (5 papers)
Partner nations: United Kingdom Germany United States

In The Last Decade

Colin J. Henderson

164 papers receiving 8.4k citations

Hit Papers

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Peers

Countries citing papers authored by Colin J. Henderson

Since Specialization

Citations

This map shows the geographic impact of Colin J. Henderson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Colin J. Henderson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Colin J. Henderson more than expected).

Fields of papers citing papers by Colin J. Henderson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Colin J. Henderson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Colin J. Henderson. The network helps show where Colin J. Henderson may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Colin J. Henderson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Colin J. Henderson Line = papers co-authored together Colin J. Henderson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals Archives of Toxicology ·Colin J. Henderson,Aileen McLaren,Andrew K. MacLeod,De‐Chen Lin,Amy Cameron,Lynsey R. Chatham,Jonathan G. Moggs,Francisco Iñesta-Vaquera,John P. Thomson,Richard R. Meehan,Probir Chakravarty,Michael Schwarz,C. Roland Wolf	2025	1
2	Application of a mouse model humanized for cytochrome P450–mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs Drug Metabolism and Disposition ·Yury Kapelyukh,Charlotte Gabel‐Jensen,A. Kenneth MacLeod,Kevin-Sebastien Coquelin,Laste Stojanovski,Laura Frame,Amy Tavendale,Colin J. Henderson,Kevin D. Read,C. Roland Wolf,Carolina Säll	2025	0
3	Cysteine post‐translational modifications regulate protein interactions of caveolin‐3 The FASEB Journal ·Fiona Ashford,Chien‐Wen Kuo,Emma Dunning,Elaine Brown,Sarah Calagan,Izzy Jayasinghe,Colin J. Henderson,William Fuller,Krzysztof Wypijewski	2024	2
4	Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolism Proceedings of the National Academy of Sciences ·Annette MacLeod,Kevin-Sebastien Coquelin,Leticia Huertas,Frederick R. C. Simeons,Jennifer Riley,Patricia Casado,Laura Guijarro,Ruth Casanueva,Laura Frame,Érika G. Pinto,Liam Ferguson,Christina Duncan,Nicole Mutter,Yoko Shishikura,Colin J. Henderson,David Cebrián,C. Roland Wolf,Kevin D. Read	2024	9
5	Use of an extensively humanized mouse model to predict the risk of drug–drug interactions in patients receiving dexamethasone Journal of Pharmacology and Experimental Therapeutics ·Jacob George,James D. Chalmers,Kevin-Sebastien Coquelin,Laura Frame,Colin J. Henderson,Yury Kapelyukh,Chim C. Lang,Kevin D. Read,Lesley A. Stanley,C. Roland Wolf	2024	2
6	Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity Environmental Pollution ·Francisco Iñesta-Vaquera,Panida Navasumrit,Colin J. Henderson,Tanya G. Frangova,Tadashi Honda,Albena T. Dinkova‐Kostova,Mathuros Ruchirawat,C. Roland Wolf	2020	11
7	Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice Drug Metabolism and Disposition ·Yury Kapelyukh,Colin J. Henderson,Nico Scheer,Anja Rode,C. Roland Wolf	2019	38
8	Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion Life Science Alliance ·Antonio Vitobello,Juliane Perner,Johanna Beil,Jiang Zhu,Alberto Del Río-Espínola,Laurent Morawiec,Magdalena Westphal,Valérie Dubost,Marc Altorfer,Ulrike Naumann,Arne Mueller,Karen Kapur,Mark L. Borowsky,Colin J. Henderson,C. Roland Wolf,Michael Schwarz,Jonathan G. Moggs,Rémi Terranova	2019	9
9	Identification of Novel Pathways of Osimertinib Disposition and Potential Implications for the Outcome of Lung Cancer Therapy Clinical Cancer Research ·Annette MacLeod,De Lin,Jeffrey Huang,Lesley A. McLaughlin,Colin J. Henderson,C. Roland Wolf	2018	25
10	Measuring in vivo responses to endogenous and exogenous oxidative stress using a novel haem oxygenase 1 reporter mouse The Journal of Physiology ·Michael McMahon,Shaohong Ding,Lourdes Acosta-Jimenez,Tania G. Frangova,Colin J. Henderson,C. Roland Wolf	2017	18
11	Olaparib, Monotherapy or with Ionizing Radiation, Exacerbates DNA Damage in Normal Tissues: Insights from a New p21 Reporter Mouse Molecular Cancer Research ·Michael McMahon,Tania G. Frangova,Colin J. Henderson,C. Roland Wolf	2016	21
12	Aryl hydrocarbon receptor is required for optimal B‐cell proliferation The EMBO Journal ·Matteo Villa,Manolis Gialitakis,Mauro Tolaini,Helena Ahlfors,Colin J. Henderson,C. Roland Wolf,Robert Brink,Brigitta Stockinger	2016	74
13	Application of Mice Humanized for CYP2D6 to the Study of Tamoxifen Metabolism and Drug–Drug Interaction with Antidepressants Drug Metabolism and Disposition ·A. Kenneth MacLeod,Lesley A. McLaughlin,Colin J. Henderson,C. Roland Wolf	2016	12
14	Activation Status of the Pregnane X Receptor Influences Vemurafenib Availability in Humanized Mouse Models Cancer Research ·A. Kenneth MacLeod,Lesley A. McLaughlin,Colin J. Henderson,C. Roland Wolf	2015	19
15	In Vivo Regulation of Human Glutathione Transferase GSTP by Chemopreventive Agents Cancer Research ·Colin J. Henderson,Aileen McLaren,C. Roland Wolf	2014	23
16	Increased Skin Papilloma Formation in Mice Lacking Glutathione Transferase GSTP Cancer Research ·Colin J. Henderson,Kenneth J. Ritchie,Aileen McLaren,Probir Chakravarty,C. Roland Wolf	2011	18
17	Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols Cancer Research ·Volker M. Arlt,Marie Stiborová,Colin J. Henderson,Martin R. Osborne,Christian A. Bieler,Eva Frei,Václav Martínek,Bruno Sopko,C. Roland Wolf,Heinz H. Schmeiser,David H. Phillips	2005	109
18	Disruption of the Glutathione Transferase Pi Class Genes Methods in enzymology on CD-ROM/Methods in enzymology ·Colin J. Henderson,C. Roland Wolf	2005	39
19	Transcription Factor Nrf2 Is Essential for Induction of NAD(P)H:Quinone Oxidoreductase 1, Glutathione S-Transferases, and Glutamate Cysteine Ligase by Broccoli Seeds and Isothiocyanates Journal of Nutrition ·Gail K. McWalter,Larry G. Higgins,Lesley I. McLellan,Colin J. Henderson,John D. Hayes,Lijiang Song,Paul J. Thornalley,Ken Itoh,Masayuki Yamamoto	2004	172
20	Delineation of human cytochromes P450 involved in the metabolism of tamoxifen British Journal of Clinical Pharmacology ·Leslie J. Daniels,E. A. Blankson,Colin J. Henderson,A. H. Harris,C. Roland Wolf,M. S. Lennard,GT Tucker	1992	8

About Colin J. Henderson

Colin J. Henderson is a scholar working on Pharmacology, Biochemistry and Oncology, having authored 166 papers that have together received 8.6k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (76 papers), Drug Transport and Resistance Mechanisms (41 papers), Genomics, phytochemicals, and oxidative stress (32 papers), Glutathione Transferases and Polymorphisms (31 papers), Drug-Induced Hepatotoxicity and Protection (15 papers), Estrogen and related hormone effects (13 papers), Carcinogens and Genotoxicity Assessment (12 papers) and Eicosanoids and Hypertension Pharmacology (11 papers). The work is most often cited by research in Pharmacology (2.4k citations), Biochemistry (567 citations) and Molecular Biology (4.6k citations). Colin J. Henderson has collaborated with scholars based in United Kingdom, Germany and United States. Frequent co-authors include C. Roland Wolf, John D. Hayes, Masayuki Yamamoto, Michael McMahon, Simon A. Chanas, Ken Itoh, Lesley I. McLellan, Aileen McLaren, Lesley A. McLaughlin and Graeme J. Moffat. Their work appears in journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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