Clifford R. Elcombe

7.0k total citations · 1 hit paper
93 papers, 5.7k citations indexed

About

Clifford R. Elcombe is a scholar working on Pharmacology, Molecular Biology and Oncology. According to data from OpenAlex, Clifford R. Elcombe has authored 93 papers receiving a total of 5.7k indexed citations (citations by other indexed papers that have themselves been cited), including 44 papers in Pharmacology, 43 papers in Molecular Biology and 19 papers in Oncology. Recurrent topics in Clifford R. Elcombe's work include Pharmacogenetics and Drug Metabolism (36 papers), Peroxisome Proliferator-Activated Receptors (21 papers) and Drug Transport and Resistance Mechanisms (17 papers). Clifford R. Elcombe is often cited by papers focused on Pharmacogenetics and Drug Metabolism (36 papers), Peroxisome Proliferator-Activated Receptors (21 papers) and Drug Transport and Resistance Mechanisms (17 papers). Clifford R. Elcombe collaborates with scholars based in United Kingdom, United States and Germany. Clifford R. Elcombe's co-authors include Angela M. Mitchell, Richard T. Mayer, M.D. Burke, S. Thompson, James R. Halpert, Tapio Haaparanta, John J. Lech, Edward A. Lock, James Winfred Bridges and John R. Foster and has published in prestigious journals such as Journal of Clinical Oncology, Cancer Research and Biochemical Journal.

In The Last Decade

Clifford R. Elcombe

92 papers receiving 5.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450

1985 1.2k citations Clifford R. Elcombe et al. Biochemical Pharmacology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Clifford R. Elcombe United Kingdom	40	2.4k	2.1k	1.5k	1.1k	970	93	5.7k
Russell A. Prough United States	49	2.9k 1.2×	2.5k 1.2×	970 0.6×	1.1k 1.0×	878 0.9×	199	7.7k
John R. Foster United Kingdom	39	1.5k 0.6×	811 0.4×	1.2k 0.8×	746 0.7×	873 0.9×	125	4.4k
Michael W.H. Coughtrie United Kingdom	42	2.6k 1.1×	2.1k 1.0×	695 0.5×	871 0.8×	634 0.7×	139	6.2k
John R. Bend United States	41	1.8k 0.8×	2.1k 1.0×	1.2k 0.8×	771 0.7×	671 0.7×	172	5.7k
Brian G. Lake United Kingdom	52	3.5k 1.5×	4.1k 2.0×	1.6k 1.0×	1.9k 1.7×	1.7k 1.7×	291	9.6k
Charles N. Falany United States	51	3.4k 1.4×	2.7k 1.3×	693 0.4×	1.2k 1.1×	653 0.7×	147	7.1k
Paul E. Thomas United States	49	3.0k 1.3×	3.9k 1.8×	884 0.6×	1.6k 1.5×	1.1k 1.1×	154	8.4k
Colin R. Jefcoate United States	54	4.2k 1.8×	3.1k 1.5×	1.6k 1.0×	1.2k 1.1×	1.7k 1.8×	203	9.6k
Johan Högberg Sweden	30	1.5k 0.6×	910 0.4×	937 0.6×	572 0.5×	611 0.6×	101	4.5k
Hansruedi Glatt Germany	60	4.7k 2.0×	2.8k 1.3×	1.6k 1.1×	1.1k 1.0×	3.4k 3.5×	315	10.8k

Countries citing papers authored by Clifford R. Elcombe

Since Specialization

Citations

This map shows the geographic impact of Clifford R. Elcombe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Clifford R. Elcombe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Clifford R. Elcombe more than expected).

Fields of papers citing papers by Clifford R. Elcombe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Clifford R. Elcombe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Clifford R. Elcombe. The network helps show where Clifford R. Elcombe may publish in the future.

Co-authorship network of co-authors of Clifford R. Elcombe

This figure shows the co-authorship network connecting the top 25 collaborators of Clifford R. Elcombe. A scholar is included among the top collaborators of Clifford R. Elcombe based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Clifford R. Elcombe. Clifford R. Elcombe is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Convertino, Matteo, Timothy R. Church, Geary W. Olsen, et al.. (2018). Stochastic Pharmacokinetic-Pharmacodynamic Modeling for Assessing the Systemic Health Risk of Perfluorooctanoate (PFOA). Toxicological Sciences. 163(1). 293–306. 39 indexed citations

Boverhof, Darrell R., M. Chamberlain, Clifford R. Elcombe, et al.. (2011). Transgenic Animal Models in Toxicology: Historical Perspectives and Future Outlook. Toxicological Sciences. 121(2). 207–233. 58 indexed citations

Elcombe, Barbara M., et al.. (2010). A Mechanism for the induction of renal tumours in male Fischer 344 rats by short-chain chlorinated paraffins. Archives of Toxicology. 84(3). 233–243. 67 indexed citations

Elcombe, Clifford R., Barbara M. Elcombe, John R. Foster, et al.. (2010). Hepatocellular hypertrophy and cell proliferation in Sprague–Dawley rats following dietary exposure to ammonium perfluorooctanoate occurs through increased activation of the xenosensor nuclear receptors PPARα and CAR/PXR. Archives of Toxicology. 84(10). 787–798. 76 indexed citations

Elcombe, Clifford R., Barbara M. Elcombe, David G. Farrar, & John R. Foster. (2007). Characterization of ammonium perfluorooctanoic acid (APFO) induced hepatomegaly in rats. Toxicology. 240(3). 172–173. 6 indexed citations

Elcombe, Clifford R., J. Odum, John R. Foster, et al.. (2002). Prediction of rodent nongenotoxic carcinogenesis: evaluation of biochemical and tissue changes in rodents following exposure to nine nongenotoxic NTP carcinogens.. Environmental Health Perspectives. 110(4). 363–375. 59 indexed citations

Elcombe, Clifford R., David Bell, Elwyn Elias, Susan C. Hasmall, & Nick Plant. (1996). Peroxisome Proliferators: Species Differences in Response of Primary Hepatocyte Cultures. Annals of the New York Academy of Sciences. 804(1). 628–635. 32 indexed citations

Bars, R., David Bell, Clifford R. Elcombe, et al.. (1992). Zone-specific inducibility of cytochrome P450 2B1/2 is retained in isolated perivenous hepatocytes. Biochemical Journal. 282(3). 635–638. 20 indexed citations

Elliott, B.M., Robert D. Combes, Clifford R. Elcombe, et al.. (1992). Alternatives to Aroclor 1254-induced S9 in in vitro genotoxicity assays. Mutagenesis. 7(3). 175–177. 41 indexed citations

10.

Bell, David & Clifford R. Elcombe. (1991). Induction of acyl-CoA oxidase and cytochrome P450IVA1 RNA in rat primary hepatocyte culture by peroxisome proliferators. Biochemical Journal. 280(1). 249–253. 55 indexed citations

11.

Styles, J.A., et al.. (1991). Recovery of hyperplastic responsiveness in rat liver after dosing with the peroxisome proliferator methylclofenapate. Carcinogenesis. 12(11). 2127–2133. 8 indexed citations

12.

Bell, David & Clifford R. Elcombe. (1991). Regulation of differentially spliced transcripts of acyl-CoA oxidase in the rat. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1090(2). 211–215. 7 indexed citations

13.

Sesardic, Dorothea, Alan R. Boobis, Edward A. Lock, et al.. (1986). Inter-relatedness of some isoenzymes of cytochrome P-450 from rat, rabbit and human, determined with monoclonal antibodies. Biochemical Journal. 236(2). 569–577. 23 indexed citations

14.

Foster, John R., Clifford R. Elcombe, Alan R. Boobis, et al.. (1986). Immunocytochemical localization of cytochrome P-450 in hepatic and extra-hepatic tissues of the rat with a monoclonal antibody against cytochrome P-450 c. Biochemical Pharmacology. 35(24). 4543–4554. 92 indexed citations

15.

Elcombe, Clifford R., Ronald B. Franklin, & John J. Lech. (1979). INDUCTION OF MICROSOMAL HEMOPROTEIN(S) P-450 IN THE RAT AND RAINBOW TROUT BY POLYHALOGENATED BIPHENYLS. Annals of the New York Academy of Sciences. 320(1 Health Effect). 193–203. 1 indexed citations

16.

Elcombe, Clifford R., Ronald B. Franklin, & John J. Lech. (1979). INDUCTION OF MICROSOMAL HEMOPROTEIN(S) P‐450 IN THE RAT AND RAINBOW TROUT BY POLYHALOGENATED BIPHENYLS*. Annals of the New York Academy of Sciences. 320(1). 193–203. 19 indexed citations

17.

Statham, Charles N., et al.. (1978). Effect of Polycyclic Aromatic Hydrocarbons on Hepatic Microsomal Enzymes and Disposition of Methylnaphthalene in Rainbow Troutin vivo. Xenobiotica. 8(2). 65–71. 73 indexed citations

18.

Dent, John G., Clifford R. Elcombe, K.J. Netter, & Jack Gibson. (1978). Rat hepatic microsomal cytochrome(s) P-450 induced by polybrominated biphenyls.. Drug Metabolism and Disposition. 6(1). 96–101. 32 indexed citations

19.

Elcombe, Clifford R. & John J. Lech. (1978). Induction of monooxygenation in rainbow trout by polybrominated biphenyls: a comparative study.. Environmental Health Perspectives. 23. 309–314. 37 indexed citations

20.

Elcombe, Clifford R., James Winfred Bridges, & R. H. Nimmo‐Smith. (1976). Substrate-elicited dissociation of a complex of cytochrome P-450 with a methylenedioxyphenyl metabolite. Biochemical and Biophysical Research Communications. 71(4). 915–919. 19 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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