James Staunton

11.0k citations

239 papers · 8.7k indexed · 1 hit paper · h-index 48

Co-authors: Peter F. Leadlay Kira J. Weissman Barrie Wilkinson Jesús Cortés John Skilling Jesús F. Aparicio Alan R. Battersby Patrick Caffrey
Topics: Microbial Natural Products and Biosynthesis (109 papers)Synthetic Organic Chemistry Methods (41 papers)Carbohydrate Chemistry and Synthesis (38 papers)
Cited by: Pharmacology Biotechnology Organic Chemistry
Journals: Nature Science Chemical Reviews
Partner nations: United Kingdom United States South Sudan

In The Last Decade

James Staunton

235 papers receiving 8.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Polyketide biosynthesis: a millennium review

2001 1.3k citations James Staunton, Kira J. Weissman Natural Product Reports profile →

Peers

Countries citing papers authored by James Staunton

Since Specialization

Citations

This map shows the geographic impact of James Staunton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Staunton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Staunton more than expected).

Fields of papers citing papers by James Staunton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James Staunton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Staunton. The network helps show where James Staunton may publish in the future.

Co-authorship network of co-authors of James Staunton

This figure shows the co-authorship network connecting the top 25 collaborators of James Staunton. A scholar is included among the top collaborators of James Staunton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James Staunton. James Staunton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Analysis of the Tetronomycin Gene Cluster: Insights into the Biosynthesis of a Polyether Tetronate Antibiotic 2008 ·ChemBioChem ·Yuliya Demydchuk,Yuhui Sun,Hui Hong,James Staunton,Jonathan B. Spencer,Peter F. Leadlay	67
2	Evidence for the Role of the monB Genes in Polyether Ring Formation during Monensin Biosynthesis 2006 ·Chemistry & Biology ·Andrew R. Gallimore,Christian B. W. Stark,Apoorva Bhatt,Barbara M. R. Harvey,Yuliya Demydchuk,Víctor M. Bolaños-García,Daniel J. Fowler,James Staunton,Peter F. Leadlay,Jonathan B. Spencer	102
3	Chain initiation on type I modular polyketide synthases revealed by limited proteolysis and ion‐trap mass spectrometry 2005 ·FEBS Journal ·Hui Hong,(unknown),Alexandros Siskos,José Garcia‐Bernardo,James Staunton,Peter F. Leadlay	25
4	Molecular Basis of Celmer's Rules: Stereochemistry of Catalysis by Isolated Ketoreductase Domains from Modular Polyketide Synthases 2005 ·Chemistry & Biology ·Alexandros Siskos,Abel Baerga‐Ortiz,Shilpa Bali,Viktor Stein,(unknown),Dieter Spiteller,Bojana Popovic,Jonathan B. Spencer,James Staunton,Kira J. Weissman,Peter F. Leadlay	95
5	Isolation and Characterization of Pre‐rapamycin, the First Macrocyclic Intermediate in the Biosynthesis of the Immunosuppressant Rapamycin by S. hygroscopicus 2004 ·Angewandte Chemie International Edition ·Matthew A. Gregory,Sabine Gaisser,Rachel E. Lill,Hui Hong,Rose Sheridan,Barrie Wilkinson,Hrvoje Petković,Alison J. Weston,Isabelle Carletti,(unknown),James Staunton,Peter F. Leadlay	36
6	Evidence for gas-phase redox chemistry inducing novel fragmentation in a complex natural product 2004 ·Organic & Biomolecular Chemistry ·Norberto Peporine Lopes,Christian B. W. Stark,James Staunton,Paul J. Gates	13
7	Intermediates Released from a Polyether‐Producing Polyketide Synthase Provide Insight into the Mechanism of Oxidative Cyclization 2003 ·Angewandte Chemie International Edition ·(unknown),Christian B. W. Stark,Ines Böhm,James Staunton,Peter F. Leadlay	35
8	Identification using LC-MSn of co-metabolites in the biosynthesis of the polyketide toxin mycolactone by a clinical isolate of Mycobacterium ulceransElectronic supplementary information (ESI) available: Experimental procedures and ESI-CID-MS/MS spectra of mycolactone and the five co-metabolites; MS3 spectrum of m/z 661 from the MS/MS of m/z 749; scheme showing the losses of mass 88 (C4H8O2) during the MS/MS of m/z 749 and the MS3 of m/z 661. See http://www.rsc.org/suppdata/cc/b3/b308163j/ 2003 ·Chemical Communications ·Hui Hong,Paul J. Gates,James Staunton,Timothy P. Stinear,Stewart T. Cole,Peter F. Leadlay,Jonathan B. Spencer	42
9	Heterologous expression in Saccharopolyspora erythraea of a pentaketide synthase derived from the spinosyn polyketide synthaseElectronic supplementary information (ESI) available: Further details of the construction of pCJR308, the fermentation of BIOT-0966 and the isolation of pentaketide lactone, 3, and figures showing the13C NMR and 1H COSY spectra of 3. See http://www.rsc.org/suppdata/ob/b3/b310740j/ 2003 ·Organic & Biomolecular Chemistry ·Christine Martin,(unknown),Rose Sheridan,Steven G. Kendrew,Barrie Wilkinson,James Staunton,Peter F. Leadlay	32
10	Fragmentation studies on monensin A and B by accurate‐mass electrospray tandem mass spectrometry 2002 ·Rapid Communications in Mass Spectrometry ·Norberto Peporine Lopes,Christian B. W. Stark,Hui Hong,Paul J. Gates,James Staunton	49
11	Skipping in a Hybrid Polyketide Synthase 2002 ·Chemistry & Biology ·(unknown),Christine Martin,Christopher J. Wilkinson,James Staunton,Peter F. Leadlay	58
12	Fragmentation studies on monensin A by sequential electrospray mass spectrometry 2002 ·The Analyst ·Norberto Peporine Lopes,Christian B. W. Stark,Paul J. Gates,James Staunton	47
13	Engineered biosynthesis of novel spinosyns bearing altered deoxyhexose substituentsElectronic supplementary information (ESI) available: 1H and 13C NMR data for compounds 5–8. See http://www.rsc.org/suppdata/cc/b2/b200536k/ 2002 ·Chemical Communications ·Sabine Gaisser,Christine Martin,Barrie Wilkinson,Rose Sheridan,Rachel E. Lill,Alison J. Weston,(unknown),Clive Waldron,Gary D. Crouse,Peter F. Leadlay,James Staunton	26
14	Novel gas-phase ion–molecule aromatic nucleophilic substitution in β-carbolines 2002 ·Chemical Communications ·Norberto Peporine Lopes,Tatiana Fonseca,John P. G. Wilkins,James Staunton,Paul J. Gates	14
15	Polyketide biosynthesis: a millennium reviewbreakdown → 2001 ·Natural Product Reports ·James Staunton,Kira J. Weissman	1287
16	The Thioesterase of the Erythromycin-Producing Polyketide Synthase: Influence of Acyl Chain Structure on the Mode of Release of Substrate Analogues from the Acyl Enzyme Intermediates 1998 ·Angewandte Chemie International Edition ·Kira J. Weissman,Cameron J. Smith,Ulf Hanefeld,Ranjana Aggarwal,Mark Bycroft,James Staunton,Peter F. Leadlay	67
17	The Pipecolate‐Incorporating Enzyme for the Biosynthesis of the Immunosuppressant Rapamycin — Nucleotide Sequence Analysis, Disruption and Heterologous Expression of Rap P from Streptomyces Hygroscopicus 1997 ·European Journal of Biochemistry ·Ariane König,Torsten Schwecke,(unknown),Günter A. Böhm,Philip A. S. Lowden,James Staunton,Peter F. Leadlay	61
18	Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: Analysis of the enzymatic domains in the modular polyketide synthase 1996 ·Gene ·Jesús F. Aparicio,István Molnár,Torsten Schwecke,Ariane König,Stephen Haydock,(unknown),James Staunton,Peter F. Leadlay	205
19	Polyketide synthesis in vitro on a modular polyketide synthase 1995 ·Chemistry & Biology ·(unknown),Jesús Cortés,Murray J. B. Brown,(unknown),James Staunton,Peter F. Leadlay	69
20	Biosynthesis of palitantin, a polyketide metabolite of Penicillium brefeldianum: 13C n.m.r. assignment and incorporation of 13C-, 2H-, and 18O2-labelled acetates 1988 ·Journal of the Chemical Society Perkin Transactions 1 ·(unknown),Ernest D. Laue,James Staunton	6

About James Staunton

James Staunton is a scholar working on Pharmacology, Organic Chemistry and Biochemistry, having authored 239 papers that have together received 8.7k indexed citations. Recurring topics across this work include Microbial Natural Products and Biosynthesis (109 papers), Synthetic Organic Chemistry Methods (41 papers) and Carbohydrate Chemistry and Synthesis (38 papers). The work is most often cited by research in Pharmacology (5.4k citations), Biotechnology (1.5k citations) and Organic Chemistry (2.8k citations). James Staunton has collaborated with scholars based in United Kingdom, United States and South Sudan. Frequent co-authors include Peter F. Leadlay, Kira J. Weissman, Barrie Wilkinson, Jesús Cortés, John Skilling, Jesús F. Aparicio, Alan R. Battersby, Patrick Caffrey, Ernest D. Laue and Christian B. W. Stark. Their work appears in journals such as Nature, Science and Chemical Reviews.

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