Morgan E. Diolaiti

2.3k citations

20 papers · 977 indexed · 2 hit papers · h-index 9

Impact in

Aging top 5%
Hematology top 5%
- Hematopoietic Stem Cell Transplantation
- Acute Myeloid Leukemia Research

Papers in

Physiology 2
- Telomeres, Telomerase, and Senescence 3
- Calcium signaling and nucleotide metabolism 2
Oncology 12
- PARP inhibition in cancer therapy 9
- CAR-T cell therapy research 2

Co-authors: Alan Ashworth Bradley A. Stohr Julia Carnevale Sietske T. Bakker P. Jonathan Li Victoria Tobin Alexander Marson Theodore L. Roth
Journals: Molecular Cancer Therapeutics (3 papers)Cancer Research (3 papers)ACS Medicinal Chemistry Letters (1 paper)Bioorganic Chemistry (1 paper)Nature (1 paper)
Partner nations: United States Ireland South Korea

In The Last Decade

Morgan E. Diolaiti

17 papers receiving 965 citations

Hit Papers

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Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function 2018 · 339 citations

Peers

Countries citing papers authored by Morgan E. Diolaiti

Since Specialization

Citations

This map shows the geographic impact of Morgan E. Diolaiti's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Morgan E. Diolaiti with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Morgan E. Diolaiti more than expected).

Fields of papers citing papers by Morgan E. Diolaiti

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Morgan E. Diolaiti. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Morgan E. Diolaiti. The network helps show where Morgan E. Diolaiti may publish in the future.

Co-authors

The 25 scholars most cited alongside Morgan E. Diolaiti, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Morgan E. Diolaiti Line = papers co-authored together Morgan E. Diolaiti links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Discovery of a Novel [6–6–5–5–6] Pentacyclic Tetrahydrocyclopentaphthalazinone as a Promising PARP Inhibitor Scaffold ACS Medicinal Chemistry Letters ·Javier Buhigas, Morgan E. Diolaiti, Alan Ashworth, Tanaji T. Talele	2025	1
2	Large scale prospective evaluation of co-folding across 557 Mac1-ligand complexes and three virtual screens bioRxiv (Cold Spring Harbor Laboratory) ·喜人薮内, G.J. Correy, J. Farré Muncharaz, Biljana Lazovi, Olivier Mailhot, R E Straub, 貴市橋, Priyadarshini Jaishankar, Vasco Neno, Wijata Agata, Javier Buhigas, 纪业江, Morgan E. Diolaiti, Pai-Mei Liu, Nic Enstice, Rani George, Nicolas (1583?-1642?). Compositeur Vallet, Seung Tae Park, Sophia Alan, John K. Fraser	2025	0
3	Structure-activity relationship studies on 2-thienylidene substituted 3-oxo-2,3-dihydrobenzofuran-7-carboxamides as poly (ADP-ribose) polymerase inhibitors Bioorganic Chemistry ·Nabilah Hana Camellia, Shigeo Hori, 洪海平, Morgan E. Diolaiti, Huadong Chen, Junhao Lu, Alan Ashworth, Gottlieb Wilhelm Becker, Joshua S. Fleishman, 廖正清, N.S. Turdieva, Шарафутдинов Ильгам Исмагилович, Ketan Patel, Megumi Murakami, Suresh V. Ambudkar, Tanaji T. Talele	2025	0
4	An engineered cysteine sensor optimized for high-throughput screening identifies regulators of intracellular thiol levels Cell chemical biology ·阿部由香, Robert E. Donahue, 柄祉金, Ying Mao, Morgan E. Diolaiti, Alan Ashworth	2025	0
5	AcrIF11 is a potent CRISPR-specific ADP-ribosyltransferase encoded by phage and plasmid mBio ·Oscar. Auteur du texte Cucherat, بنفشه محمدی, Yuping Li, Adair L. Borges, Jenny Y. Zhang, Nyirambangutse B, Dae-Sung Yoon, Zdravko Kvržić, G.J. Correy, Morgan E. Diolaiti, 舛尾伸広, Alan Ashworth, R. M. Stroud, Mark J. S. Kelly, Joseph Bondy‐Denomy, James S. Fraser	2025	1
6	De novo design of drug-binding proteins with predictable binding energy and specificity Science ·Lei Lü, Xuxu Gou, Cui Deng, Junfeng Dai, Hyunjun Yang, Xiaofang Zhong, K. Minam, Luh Putu Nindia Sastiari, Hyunil Jo, Yibing Wu, Morgan E. Diolaiti, Alan Ashworth, Nicholas F. Polizzi, William F. DeGrado	2024	22
7	PARP7 Inhibitors and AHR Agonists Act Synergistically across a Wide Range of Cancer Models Molecular Cancer Therapeutics ·Huadong Chen, Xuxu Gou, J. F. Rieken, Patrick C. O’Leary, Morgan E. Diolaiti, Alan Ashworth	2024	6
8	A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo PLoS Pathogens ·Taha Y. Taha, Rahul K. Suryawanshi, Irene P. Chen, G.J. Correy, 久美小越, Patrick C. O’Leary, Manasi P. Jogalekar, Morgan E. Diolaiti, Miguel Ronderos Dumit, Chia-Lin Tsou, Senthan Prasanth, Mauricio Montaño, Luis Martínez‐Sobrido, Nevan J. Krogan, Alan Ashworth, James S. Fraser, Mélanie Ott	2023	11
9	Ablation of Cullin-5 in Primary Human T Cells Improves Tumor Killing and Persistence in BCMA-Targeting CAR-T Cells in a Multiple Myeloma Model Blood ·Adriana Adriani, Alexis Talbot, Winston Hurst, Nupura Kale, Zhongmei Li, Morgan E. Diolaiti, Amy Chen, Joseph Muldoon, Chang Liu, Thomas Martin, Justin Eyquem, Julia Carnevale	2023	2
10	PLX038: A Long-Acting Topoisomerase I Inhibitor With Robust Antitumor Activity in ATM -Deficient Tumors and Potent Synergy With PARP Inhibitors Molecular Cancer Therapeutics ·Anish Thomas, Shaun D. Fontaine, Morgan E. Diolaiti, Parth Desai, Rajesh Kumar, Nobuyuki Takahashi, Linda Sciuto, Samantha Nichols, Alan Ashworth, Felix Y. Feng, Gary W. Ashley, Minh Nguyen, Yves Pommier, Daniel V. Santi	2022	7
11	A Whole-Genome CRISPR Screen Identifies AHR Loss as a Mechanism of Resistance to a PARP7 Inhibitor Molecular Cancer Therapeutics ·Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth	2022	17
12	Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2 Cancer Research ·Patrick C. O’Leary, Huadong Chen, Javier Buhigas, Irna Rutbaniyah, Benjamin J. Polacco, Andrew S. McNeal, Tanushree Shenoy, Nupura Kale, Julia Carnevale, Erica Stevenson, David A. Quigley, Jonathan Chou, Felix Y. Feng, Danielle L. Swaney, Nevan J. Krogan, Minkyu Kim, Morgan E. Diolaiti, Alan Ashworth	2022	17
13	Abstract PD15-08: Window of opportunity trial of neoadjuvant olaparib and durvalumab for triple negative or low ER-positive breast cancer Cancer Research ·Seock‐Ah Im, Kyung-Hun Lee, Ahrum Min, Daewon Lee, Tae Yong Kim, W.K. van Leeuwen, Jiwon Koh, Gi Jeong Cheon, Yoon-Jung Shin, Yujin Kim, Hyeong‐Gon Moon, Wonshik Han, Han‐Byoel Lee, Morgan E. Diolaiti, David A. Quigley, Alan Ashworth, Nariya Cho	2022	5
14	A Very Long-Acting PARP Inhibitor Suppresses Cancer Cell Growth in DNA Repair-Deficient Tumor Models Cancer Research ·Shaun D. Fontaine, Gary W. Ashley, Peter J. Houghton, Raushan T. Kurmasheva, Morgan E. Diolaiti, Alan Ashworth, Cody J. Peer, Sunita S Malaj, William D. Figg, Denis Beckford-Vera, Daniel V. Santi	2020	16
15	Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity Journal of Medicinal Chemistry ·Uday Kiran Velagapudi, Marie-France Langelier, Cristina Delgado-Martín, Morgan E. Diolaiti, Sietske T. Bakker, Alan Ashworth, Bhargav A. Patel, 김덕일, John M. Pascal, Tanaji T. Talele	2019	35
16	In Situ Visualization of Telomere Length, Telomere Elongation, and TERT Expression in Single Cells Current Protocols in Cell Biology ·Ajay Ravindranathan, Morgan E. Diolaiti, Beth A. Cimini, Bradley A. Stohr	2019	1
17	Preliminary development of an assay for detection of TERT expression, telomere length, and telomere elongation in single cells PLoS ONE ·Ajay Ravindranathan, Beth A. Cimini, Morgan E. Diolaiti, Bradley A. Stohr	2018	8
18	Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function Cell ·Eric Shifrut, Julia Carnevale, Victoria Tobin, Theodore L. Roth, Jonathan M. Woo, Masaaki Kaniwa, P. Jonathan Li, Morgan E. Diolaiti, Alan Ashworth, Alexander Marson Hit paper breakdown →	2018	339
19	Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells Nature ·Johanna Flach, Sietske T. Bakker, Mary Mohrin, Seung-Hwa Park, Eric M. Pietras, Damien Reynaud, Silvia Álvarez, Morgan E. Diolaiti, Fernando Ugarte, E. Camilla Forsberg, Michelle M. Le Beau, Bradley A. Stohr, Juan Méndez, Ciaran G. Morrison, Emmanuelle Passegué Hit paper breakdown →	2014	466
20	In situ visualization of telomere elongation patterns in human cells Nucleic Acids Research ·Morgan E. Diolaiti, Beth A. Cimini, Robin Kageyama, Florie A. Charles, Bradley A. Stohr	2013	23

About Morgan E. Diolaiti

Morgan E. Diolaiti is a scholar working on Physiology, Oncology, Molecular Biology, Immunology and Biochemistry, having authored 20 papers that have together received 977 indexed citations. Recurring topics across this work include PARP inhibition in cancer therapy (9 papers), DNA Repair Mechanisms (6 papers), CRISPR and Genetic Engineering (6 papers), Telomeres, Telomerase, and Senescence (3 papers), BRCA gene mutations in cancer (2 papers), CAR-T cell therapy research (2 papers), Monoclonal and Polyclonal Antibodies Research (2 papers) and Calcium signaling and nucleotide metabolism (2 papers). The work is most often cited by research in Aging (40 citations), Hematology (187 citations), Immunology (256 citations), Oncology (300 citations) and Molecular Biology (618 citations). Morgan E. Diolaiti has collaborated with scholars based in United States, Ireland and South Korea. Frequent co-authors include Alan Ashworth, Bradley A. Stohr, Julia Carnevale, Sietske T. Bakker, P. Jonathan Li, Victoria Tobin, Alexander Marson, Theodore L. Roth, Eric Shifrut and Jonathan M. Woo. Their work appears in journals such as Molecular Cancer Therapeutics, Cancer Research, ACS Medicinal Chemistry Letters, Bioorganic Chemistry and Nature.

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