Theodore L. Roth

13.2k total citations · 4 hit papers
28 papers, 3.6k citations indexed

About

Theodore L. Roth is a scholar working on Molecular Biology, Oncology and Immunology. According to data from OpenAlex, Theodore L. Roth has authored 28 papers receiving a total of 3.6k indexed citations (citations by other indexed papers that have themselves been cited), including 21 papers in Molecular Biology, 10 papers in Oncology and 10 papers in Immunology. Recurrent topics in Theodore L. Roth's work include CRISPR and Genetic Engineering (16 papers), CAR-T cell therapy research (10 papers) and Immune Cell Function and Interaction (4 papers). Theodore L. Roth is often cited by papers focused on CRISPR and Genetic Engineering (16 papers), CAR-T cell therapy research (10 papers) and Immune Cell Function and Interaction (4 papers). Theodore L. Roth collaborates with scholars based in United States, Japan and Singapore. Theodore L. Roth's co-authors include Dorian B. McGavern, Debasis Nayak, Kara N. Corps, Alexander Marson, Tatjana Atanasijević, Lawrence L. Latour, Alan P. Koretsky, Eric Shifrut, P. Jonathan Li and Victoria Tobin and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Theodore L. Roth

28 papers receiving 3.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Microglia Development and Function

2014 849 citations Debasis Nayak, Theodore L. Roth et al. profile →
Inflammation and Neuroprotection in Traumatic Brain Injury

2015 643 citations Theodore L. Roth, Dorian B. McGavern et al. profile →
Transcranial amelioration of inflammation and cell death after brain injury

2013 467 citations Theodore L. Roth, Debasis Nayak et al. Nature profile →
Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function

2018 339 citations Eric Shifrut, Julia Carnevale et al. Cell profile →

Peers

Theodore L. Roth

MB

NEURO

IMMUN

ONCOL

NEURO

Farshid Noorbakhsh Iran

Robert Weissert Germany

Niels Hellings Belgium

Thomas Skripuletz Germany

Igal Ifergan Canada

Svetlana M. Stamatovic United States

Romain Cayrol Canada

Anuja Ghorpade United States

Fabrizio Giuliani Canada

Hania Kébir Canada

Farshid Noorbakhsh Iran

Theodore L. Roth

1.4k ×0.9

MB

506 ×0.5

NEURO

784 ×0.9

IMMUN

440 ×0.6

ONCOL

234 ×0.4

NEURO

Citations per year, relative to Theodore L. Roth Theodore L. Roth (= 1×) peers Farshid Noorbakhsh

Countries citing papers authored by Theodore L. Roth

Since Specialization

Citations

This map shows the geographic impact of Theodore L. Roth's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Theodore L. Roth with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Theodore L. Roth more than expected).

Fields of papers citing papers by Theodore L. Roth

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Theodore L. Roth. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Theodore L. Roth. The network helps show where Theodore L. Roth may publish in the future.

Co-authorship network of co-authors of Theodore L. Roth

This figure shows the co-authorship network connecting the top 25 collaborators of Theodore L. Roth. A scholar is included among the top collaborators of Theodore L. Roth based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Theodore L. Roth. Theodore L. Roth is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

1.

Roth, Theodore L., et al.. (2025). Non-viral intron knock-ins for targeted gene integration into human T cells and for T-cell selection. Nature Biomedical Engineering. 9(8). 1309–1319. 2 indexed citations

2.

Fanton, Alison, Jade Martins, Laine Goudy, et al.. (2025). Site-specific DNA insertion into the human genome with engineered recombinases. Nature Biotechnology. 1 indexed citations

3.

Lee, Youjin, Derek Bogdanoff, Yutong Wang, et al.. (2021). XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment. Science Advances. 7(17). 83 indexed citations

4.

Müller, Yannick D., Duy Nguyen, Leonardo M. R. Ferreira, et al.. (2021). The CD28-Transmembrane Domain Mediates Chimeric Antigen Receptor Heterodimerization With CD28. Frontiers in Immunology. 12. 639818–639818. 85 indexed citations

5.

Ferguson, Lucas, Benjamin E. Smith, Ryan Apathy, et al.. (2021). Robust T cell activation requires an eIF3-driven burst in T cell receptor translation. eLife. 10. 16 indexed citations

6.

Roth, Theodore L., P. Jonathan Li, Franziska Blaeschke, et al.. (2020). Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies. Cell. 181(3). 728–744.e21. 130 indexed citations

7.

Ng, Melissa, Theodore L. Roth, Ventura F. Mendoza, Alexander Marson, & Trevor D. Burt. (2019). Helios enhances the preferential differentiation of human fetal CD4 ⁺ naïve T cells into regulatory T cells. Science Immunology. 4(41). 34 indexed citations

8.

Schober, Kilian, Thomas Müller, Simon Grassmann, et al.. (2019). Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function. Nature Biomedical Engineering. 3(12). 974–984. 115 indexed citations

9.

Leenay, Ryan T., Amirali Aghazadeh, Joseph Hiatt, et al.. (2019). Large dataset enables prediction of repair after CRISPR–Cas9 editing in primary T cells. Nature Biotechnology. 37(9). 1034–1037. 82 indexed citations

10.

Nguyen, David N., Theodore L. Roth, P. Jonathan Li, et al.. (2019). Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency. Nature Biotechnology. 38(1). 44–49. 194 indexed citations

11.

Farboud, Behnom, Erin Jarvis, Theodore L. Roth, et al.. (2018). Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms. Journal of Visualized Experiments. 12 indexed citations

12.

Farboud, Behnom, Erin Jarvis, Theodore L. Roth, et al.. (2018). Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms. Journal of Visualized Experiments. 34 indexed citations

13.

Hultquist, Judd F., Joseph Hiatt, Kathrin Schumann, et al.. (2018). CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions. Nature Protocols. 14(1). 1–27. 78 indexed citations

14.

Shifrut, Eric, Julia Carnevale, Victoria Tobin, et al.. (2018). Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function. Cell. 175(7). 1958–1971.e15. 339 indexed citations breakdown →

15.

Roth, Theodore L., Yuriy Baglaenko, Patrick M. Brauer, et al.. (2018). Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins. Journal of Immunological Methods. 457. 33–40. 39 indexed citations

16.

Roth, Theodore L., Hayley M. Bennett, Magali Soumillon, et al.. (2018). Light-activated cell identification and sorting (LACIS) for selection of edited clones on a nanofluidic device. Communications Biology. 1(1). 41–41. 39 indexed citations

17.

Zhang, Yang, Theodore L. Roth, Elizabeth Gray, et al.. (2016). Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node. eLife. 5. 72 indexed citations

18.

Roth, Theodore L., Ljiljana Milenković, & Matthew P. Scott. (2014). A Rapid and Simple Method for DNA Engineering Using Cycled Ligation Assembly. PLoS ONE. 9(9). e107329–e107329. 17 indexed citations

19.

Nayak, Debasis, Kory Johnson, Sara Heydari, et al.. (2013). Type I Interferon Programs Innate Myeloid Dynamics and Gene Expression in the Virally Infected Nervous System. PLoS Pathogens. 9(5). e1003395–e1003395. 48 indexed citations

20.

Roth, Theodore L., Debasis Nayak, Tatjana Atanasijević, et al.. (2013). Transcranial amelioration of inflammation and cell death after brain injury. Nature. 505(7482). 223–228. 467 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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