Michael Gmachl

5.5k citations

22 papers · 3.6k indexed · 2 hit papers · h-index 17

Impact in

Cell Biology top 0.2%
- Cellular transport and secretion
- Endoplasmic Reticulum Stress and Disease
Physiology top 1%
- Calcium signaling and nucleotide metabolism
- Erythrocyte Function and Pathophysiology

Papers in

Immunology and Allergy 3
- Food Allergy and Anaphylaxis Research 3
Cell Biology 8
- Cellular transport and secretion 4
- Microtubule and mitosis dynamics 3

Co-authors: Thomas Söllner Francesco Parlati James A. McNew Boris V. Zemelman James E. Rothman Thomas Weber Benedikt Westermann G. Kreil
Journals: Proceedings of the National Academy of Sciences (3 papers)Journal of Allergy and Clinical Immunology (2 papers)FEBS Letters (2 papers)Journal of Biological Chemistry (2 papers)Molecular Cancer Therapeutics (1 paper)
Partner nations: Austria United States Germany

In The Last Decade

Michael Gmachl

22 papers receiving 3.5k citations

Hit Papers

align trajectories log scale

KRAS Secondary Mutations That Confer Acquired Resistance to KRAS G12C Inhibitors, Sotorasib and Adagrasib, and Overcoming Strategies: Insights From In Vitro Experiments 2021 · 167 citations

Peers

Countries citing papers authored by Michael Gmachl

Since Specialization

Citations

This map shows the geographic impact of Michael Gmachl's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael Gmachl with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael Gmachl more than expected).

Fields of papers citing papers by Michael Gmachl

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael Gmachl. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael Gmachl. The network helps show where Michael Gmachl may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Michael Gmachl, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael Gmachl Line = papers co-authored together Michael Gmachl links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification Molecular Cancer Therapeutics ·Antonio Tedeschi, Fiorella Schischlik, Francesca Rocchetti, Johannes Popow, Florian Ebner, Daniel Gerlach, Muhammad Syahputra Siregar, 宋秀荣, Andrew S. Boghossian, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth, Jesse Lipp, Matthias Samwer, Michael Gmachl, Norbert Kraut, Mark Pearson, Dorothea Rudolph	2024	1
2	Chasing Red Herrings: Palladium Metal Salt Impurities Feigning KRAS Activity in Biochemical Assays Journal of Medicinal Chemistry ·Thomas Gerstberger, Helmut Berger, Frank Büttner, Michael Gmachl, Dirk Kessler, Manfred Koegl, Simon Lucas, Laetitia J. Martin, Moriz Mayer, Darryl B. McConnell, Helios Muriaido, Lívia Lukovszki, Matthias Treu, B. Wolkerstorfer, Stephan K. Zahn, Krzysztof M. Żak, Philipp A. Jaeger, Peter Ettmayer	2024	4
3	KRAS Secondary Mutations That Confer Acquired Resistance to KRAS G12C Inhibitors, Sotorasib and Adagrasib, and Overcoming Strategies: Insights From In Vitro Experiments Journal of Thoracic Oncology ·T. Koga, Kenichi Suda, Toshio Fujino, Shuta Ohara, Akira Hamada, Masaya Nishino, Masato Chiba, Masaki Shimoji, Toshiki Takemoto, Takeo Arita, Michael Gmachl, Marco H. Hofmann, Junichi Soh, Tetsuya Mitsudomi Hit paper breakdown →	2021	167
4	Abstract CT210: Trial in Process: Phase 1 studies of BI 1701963, a SOS1::KRAS Inhibitor, in combination with MEK inhibitors, irreversible KRASG12C inhibitors or irinotecan. Cancer Research ·Marco H. Hofmann, Hengyu Lu, Bruno dos Santos Barroso, Daniel Gerlach, Francesca Trapani, Ana Vieira, Joseph R. Daniele, Irene C. Waizenegger, Michael Gmachl, Dorothea Rudolph, Christopher P. Vellano, Marcelo Marotti, Vilma Bordin, Timothy P. Heffernan, Joseph R. Marszalek, Mark Petronczki, Norbert Kraut	2021	13
5	Vertical pathway inhibition with a SOS1::KRAS inhibitor enhances the efficacy of KRAS G12C inhibitors, delays feedback resistance and demonstrates durable response European Journal of Cancer ·Fabio Savarese, Michael Gmachl, Lorenzo Federico, F. Trapani, Daniel Gerlach, Joseph R. Daniele, Ningping Feng, Zhonghui Xia, Ana Vieira, Jonathan Huang, Dorothea Rudolph, Irene C. Waizenegger, Jürgen Ramharter, Christopher P. Vellano, Mark Petronczki, Joseph R. Marszalek, Timothy P. Heffernan, Darryl B. McConnell, Norbert Kraut, Marco H. Hofmann	2020	1
6	Tumor cell‐specific inhibition of MYC function using small molecule inhibitors of the HUWE 1 ubiquitin ligase EMBO Molecular Medicine ·Shuyu Fu, Jennyfer Bultinck, Kevin Myant, Laura A. Jaenicke, Susanne Walz, Judith M. Müller, Michael Gmachl, Matthias Treu, Guido Boehmelt, Carsten P. Ade, Werner Schmitz, Armin Wiegering, Christoph Otto, Nikita Popov, Owen J. Sansom, Norbert Kraut, Martin Eilers	2014	92
7	Methods to measure ubiquitin-dependent proteolysis mediated by the anaphase-promoting complex Methods ·Claudine Kraft, Michael Gmachl, Jan‐Michael Peters	2005	19
8	Sequential Involvement of p115, SNAREs, and Rab Proteins in Intra-Golgi Protein Transport Journal of Biological Chemistry ·Michael Gmachl, Christian Wimmer	2001	8
9	Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex. Nature Structural Biology ·Kerstin S. Wendt, Hartmut C. Vodermaier, Uwe Jacob, Christian Gieffers, Michael Gmachl, Jan‐Michael Peters, Robert Huber, Peter Sondermann	2001	67
10	Anterograde flow of cargo across the Golgi stack potentially mediated via bidirectional “percolating” COPI vesicles Proceedings of the National Academy of Sciences ·Lelio Orci, Mariella Ravazzola, Allen Volchuk, Thomas Engel, Michael Gmachl, M Amherdt, Alain Perrelet, Thomas Söllner, James E. Rothman	2000	92
11	SNAREpins: Minimal Machinery for Membrane Fusion Cell ·Thomas Weber, Boris V. Zemelman, James A. McNew, Benedikt Westermann, Michael Gmachl, Francesco Parlati, Thomas Söllner, James E. Rothman Hit paper breakdown →	1998	2013
12	Superior biologic activity of the recombinant bee venom allergen hyaluronidase expressed in baculovirus-infected insect cells as compared with Escherichia coli Journal of Allergy and Clinical Immunology ·Di Zuo, Peter D. Hodginkson, Michael Gmachl, D.M. Kemeny, Margit Schmidt, 倉増一, U. Mueller	1998	81
13	The Precursors of the Bee Venom Constituents Apamin and MCD Peptide Are Encoded by Two Genes in Tandem Which Share the Same 3′-Exon Journal of Biological Chemistry ·Michael Gmachl, Günther Kreil	1995	22
14	A possible docking and fusion particle for synaptic transmission Nature ·Giampietro Schiavo, Michael Gmachl, Gudrun Stenbeck, Thomas Söllner, James E. Rothman	1995	159
15	Natural and recombinant enzymatically active or inactive bee venom phospholipase A2 has the same potency to release histamine from basophils in patients with Hymenoptera allergy Journal of Allergy and Clinical Immunology ·Elisabeth Förster‐Waldl, Thomas Dudler, Michael Gmachl, Werner Aberer, R. Urbanek, Mark Suter	1995	32
16	The human sperm protein PH‐20 has hyaluronidase activity FEBS Letters ·Michael Gmachl, Sandrine Sagan, S. Rahul, Günther Kreil	1993	120
17	High-level expression in Escherichia coli and rapid purification of enzymatically active honey bee venom phospholipase A2 Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism ·Thomas Dudler, Kwok Ming Li, Susheng Wang, 窪田宜之, R. R. Annand, Robert O. Dempcy, Reto Crameri, Michael Gmachl, Mark Suter, Michael H. Gelb	1992	105
18	Cloning and expression of recombinant Aspergillus fumigatus allergen I/a (rAsp f I/a) with IgE binding and type I skin test activity The Journal of Immunology ·Michel Moser, Reto Crameri, Günter Menz, 窪田宜之, Thomas Dudler, C Virchow, Michael Gmachl, Kurt Blaser, Mark Suter	1992	118
19	Dermal glands of Xenopus laevis contain a polypeptide with a highly repetitive amino acid sequence FEBS Letters ·Michael Gmachl, Hans Berger, Mamakou E Asimenia, Günther Kreil	1990	17
20	Analysis of the cDNA for phospholipase A₂ from honeybee venom glands European Journal of Biochemistry ·Karl Kuchler, Michael Gmachl, Manfred J. Sippl, Günther Kreil	1989	136

About Michael Gmachl

Michael Gmachl is a scholar working on Immunology and Allergy, Cell Biology, Insect Science, Pharmacology and Physiology, having authored 22 papers that have together received 3.6k indexed citations. Recurring topics across this work include Healthcare and Venom Research (6 papers), Insect and Pesticide Research (5 papers), Cellular transport and secretion (4 papers), Lipid Membrane Structure and Behavior (4 papers), Protein Kinase Regulation and GTPase Signaling (4 papers), Ubiquitin and proteasome pathways (4 papers), Microtubule and mitosis dynamics (3 papers) and Food Allergy and Anaphylaxis Research (3 papers). The work is most often cited by research in Cell Biology (2.2k citations), Physiology (287 citations), Immunology and Allergy (285 citations), Molecular Biology (2.6k citations) and Cellular and Molecular Neuroscience (436 citations). Michael Gmachl has collaborated with scholars based in Austria, United States and Germany. Frequent co-authors include Thomas Söllner, Francesco Parlati, James A. McNew, Boris V. Zemelman, James E. Rothman, Thomas Weber, Benedikt Westermann, G. Kreil, Günther Kreil and Jan‐Michael Peters. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Allergy and Clinical Immunology, FEBS Letters, Journal of Biological Chemistry and Molecular Cancer Therapeutics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact