Timothy P. Heffernan

18.2k citations

38 papers · 1.3k indexed · h-index 18

Molecular Biology top 10%
Oncology top 5%
Cancer Research top 5%
Hematology top 5%
Genetics top 5%

Co-authors: William K. Kaufmann Marila Cordeiro‐Stone Dennis A. Simpson Richard S. Paules Alexandra N. Heinloth Christopher A. Bristow P. Andrew Futreal Scott Kopetz
Topics: Cancer-related Molecular Pathways (10 papers)DNA Repair Mechanisms (9 papers)Melanoma and MAPK Pathways (5 papers)
Cited by: Cancer Research Hematology Oncology
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry Journal of Clinical Oncology
Partner nations: United States Austria United Kingdom

In The Last Decade

Timothy P. Heffernan

34 papers receiving 1.3k citations

Peers

Countries citing papers authored by Timothy P. Heffernan

Since Specialization

Citations

This map shows the geographic impact of Timothy P. Heffernan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Timothy P. Heffernan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Timothy P. Heffernan more than expected).

Fields of papers citing papers by Timothy P. Heffernan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Timothy P. Heffernan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Timothy P. Heffernan. The network helps show where Timothy P. Heffernan may publish in the future.

Co-authorship network of co-authors of Timothy P. Heffernan

This figure shows the co-authorship network connecting the top 25 collaborators of Timothy P. Heffernan. A scholar is included among the top collaborators of Timothy P. Heffernan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Timothy P. Heffernan. Timothy P. Heffernan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	CBX250 Is a Novel Cathepsin G Peptide-HLA-Targeting T Cell Engager That Exhibits High Tumor Antigen Selectivity and Potent Antileukemic Activity In Vivo 2024 ·Blood ·Benjamin H. Lee,Geraldine L. C. Paulus,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Michael F. Princiotta,Chunhua Shi,Jun Yan,(unknown),Ningping Feng,Jeffrey J. Molldrem,Timothy P. Heffernan,Gheath Alatrash,(unknown)	0
2	Preclinical development of 1B7/CD3, a novel anti-TSLPR bispecific antibody that targets CRLF2-rearranged Ph-like B-ALL 2023 ·Leukemia ·(unknown),Chunhua Shi,Guojun Yang,(unknown),Qing Shi,Amin Al-Shami,(unknown),Melinda Smith,Qing Chang,(unknown),(unknown),Timothy Lofton,Michelle A. González,Qi Zhang,Dongxing Zha,Sarah K. Tasian,Nitin Jain,Marina Konopleva,Timothy P. Heffernan,Jeffrey J. Molldrem	6
3	Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma 2023 ·Clinical Cancer Research ·Abdullah A. Osman,Emre Arslan,(unknown),Chieko Michikawa,Antje Lindemann,Katarzyna Tomczak,Wangjie Yu,Vlad C. Sandulache,Wencai Ma,Li Shen,Jing Wang,Anand K. Singh,Mitchell J. Frederick,Nakia D. Spencer,(unknown),Timothy P. Heffernan,W. Fraser Symmans,Kunal Rai,Jeffrey N. Myers	32
4	Anti‐MS4A4A Antibody Modulates Myeloid Cell Biology and TREM2 Signaling 2023 ·Alzheimer s & Dementia ·Yaíma L. Lightfoot,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Jeffrey J. Molldrem,Timothy P. Heffernan,Timothy Lofton,(unknown),Edoardo Marcora,Alison Goate,William J. Ray	0
5	Targeting Glucose Metabolism Sensitizes Pancreatic Cancer to MEK Inhibition 2021 ·Cancer Research ·Yan Liang,Bo Tu,Jun Yao,Jing Gong,Alessandro Carugo,Christopher A. Bristow,Qiuyun Wang,Cihui Zhu,Bingbing Dai,Ya’an Kang,Leng Han,Ningping Feng,(unknown),Jason B. Fleming,Timothy P. Heffernan,Wantong Yao,Haoqiang Ying	30
6	Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with PIK3CA/AKT1 mutations 2021 ·Oncogene ·Maryam Shariati,Kurt W. Evans,Xiaofeng Zheng,Christopher A. Bristow,Patrick Kwok‐Shing Ng,(unknown),Coya Tapia,Fei Yang,Alessandro Carugo,Timothy P. Heffernan,Michael Peoples,Debu Tripathy,Funda Meric‐Bernstam	17
7	The cytosolic iron–sulfur cluster assembly (CIA) pathway is required for replication stress tolerance of cancer cells to Chk1 and ATR inhibitors 2021 ·npj Breast Cancer ·Abena B. Redwood,Xiaomei Zhang,Sahil Seth,Zhongqi Ge,Wendy Bindeman,Xinhui Zhou,(unknown),Timothy P. Heffernan,Helen Piwnica‐Worms	9
8	First-in-human biomarker-driven phase I trial of the potent and selective glutaminase-1 (GLS1) inhibitor IACS-6274 (IPN60090) in patients (pts) with molecularly selected advanced solid tumors. 2021 ·Journal of Clinical Oncology ·Timothy A. Yap,Ecaterina E. Dumbrava,Jordi Rodón,David S. Hong,Shubham Pant,Daniel D. Karp,Sarina A. Piha‐Paul,Vivek Subbiah,Apostolia M. Tsimberidou,Siqing Fu,Filip Jankú,(unknown),(unknown),(unknown),(unknown),Yan Moore,Michael Soth,(unknown),Timothy P. Heffernan,Philip Jones	11
9	Targeting DNA damage response in head and neck cancers through abrogation of cell cycle checkpoints 2020 ·International Journal of Radiation Biology ·Jessica M. Molkentine,David Molkentine,Kathleen A. Bridges,Tongxin Xie,Liangpeng Yang,Aakash Sheth,Timothy P. Heffernan,D.A. Clump,(unknown),Robert L. Ferris,Jeffrey N. Myers,Mitchell J. Frederick,Kathryn A. Mason,Raymond E. Meyn,Curtis R. Pickering,Heath D. Skinner	29
10	Efficacy of the combination of MEK and CDK4/6 inhibitors in vitro and in vivo in KRAS mutant colorectal cancer models 2020 ·UNC Libraries ·Ji Yuan Wu,Garth Powis,Feng Tian,Timothy P. Heffernan,Ningping Feng,Jason Gay,Qing Chang,Carlo Toniatti,Lawrence N. Kwong,Timothy L. Helms,Michael S. Lee,Scott Kopetz	5
11	A functional genomic screen in vivo identifies CEACAM5 as a clinically relevant driver of breast cancer metastasis 2018 ·npj Breast Cancer ·Emily Powell,Jiansu Shao,(unknown),Christopher A. Bristow,Zhongqi Ge,Michael Peoples,Frederick S. Robinson,Sabrina L. Jeter-Jones,Christopher Schlosberg,Caitlin L. Grzeskowiak,Fei Yang,Yun Wu,Ignacio I. Wistuba,Stacy Moulder,W. Fraser Symmans,Kenneth L. Scott,John R. Edwards,Han Liang,Timothy P. Heffernan,Helen Piwnica‐Worms	39
12	PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy 2018 ·Cell stem cell ·Joanne I. Hsu,Tajhal Dayaram,Ayala Tovy,Étienne De Braekeleer,Mira Jeong,Feng Wang,Jianhua Zhang,Timothy P. Heffernan,Sonal Gera,Jeffrey J. Kovacs,Joseph R. Marszalek,Christopher A. Bristow,Yuanqing Yan,Guillermo Garcia‐Manero,Hagop M. Kantarjian,George S. Vassiliou,P. Andrew Futreal,Lawrence A. Donehower,Koichi Takahashi,Margaret A. Goodell	268
13	HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome 2013 ·Oncogene ·(unknown),Turgut Dogruluk,(unknown),Y. Zhang,Timothy P. Heffernan,Remco van Doorn,Chad J. Creighton,Lih‐Shen Chin,(unknown)	53
14	ATR–Chk1 Pathway Inhibition Promotes Apoptosis after UV Treatment in Primary Human Keratinocytes: Potential Basis for the UV Protective Effects of Caffeine 2009 ·Journal of Investigative Dermatology ·Timothy P. Heffernan,Masaoki Kawasumi,Alessandra Blasina,Kenna Anderes,Allan H. Conney,Paul Nghiem	66
15	Feedback Circuit among INK4 Tumor Suppressors Constrains Human Glioblastoma Development 2008 ·Cancer Cell ·Ruprecht Wiedemeyer,Cameron Brennan,Timothy P. Heffernan,Yonghong Xiao,John E. Mahoney,Alexei Protopopov,Hongwu Zheng,Graham R. Bignell,Frank B. Furnari,Webster K. Cavenee,William C. Hahn,Koichi Ichimura,V. Peter Collins,Gerald C. Chu,Michael R. Stratton,Keith L. Ligon,P. Andrew Futreal,Lynda Chin	93
16	Cdc7-Dbf4 and the Human S Checkpoint Response to UVC 2007 ·Journal of Biological Chemistry ·Timothy P. Heffernan,Keziban Ünsal-Kaçmaz,Alexandra N. Heinloth,Dennis A. Simpson,Richard S. Paules,Aziz Sancar,Marila Cordeiro‐Stone,William K. Kaufmann	56
17	Checkpoint Regulation of Replication Dynamics in UV-Irradiated Human Cells 2006 ·Cell Cycle ·Paul D. Chastain,Timothy P. Heffernan,Kathleen R. Nevis,Lin Li,William K. Kaufmann,David G. Kaufman,Marila Cordeiro‐Stone	47
18	Telomerase expression is sufficient for chromosomal integrity in cells lacking p53 dependent G1 checkpoint function. 2005 ·Journal of Carcinogenesis ·Dennis A. Simpson,Elizabeth Livanos,Timothy P. Heffernan,William K. Kaufmann	16
19	Overproduction of DNA polymerase eta does not raise the spontaneous mutation rate in diploid human fibroblasts 2005 ·DNA repair ·(unknown),Nana Nikolaishvili‐Feinberg,Miriam F. Bryant,Douglas D. Luche,Timothy P. Heffernan,Dennis A. Simpson,Fumio Hanaoka,William K. Kaufmann,Marila Cordeiro‐Stone	24
20	Spine-Board Transfer Techniques and the Unstable Cervical Spine 2004 ·Spine ·Gianluca Del Rossi,MaryBeth Horodyski,Timothy P. Heffernan,Michael E. Powers,(unknown),Denis Brunt,Glenn R. Rechtine	49

About Timothy P. Heffernan

Timothy P. Heffernan is a scholar working on Cancer Research, Oncology and Genetics, having authored 38 papers that have together received 1.3k indexed citations. Recurring topics across this work include Cancer-related Molecular Pathways (10 papers), DNA Repair Mechanisms (9 papers) and Melanoma and MAPK Pathways (5 papers). The work is most often cited by research in Cancer Research (378 citations), Hematology (210 citations) and Oncology (476 citations). Timothy P. Heffernan has collaborated with scholars based in United States, Austria and United Kingdom. Frequent co-authors include William K. Kaufmann, Marila Cordeiro‐Stone, Dennis A. Simpson, Richard S. Paules, Alexandra N. Heinloth, Christopher A. Bristow, P. Andrew Futreal, Scott Kopetz, Jeffrey J. Kovacs and Joseph R. Marszalek. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Oncology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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