Markus A. Rüegg

25.7k citations

184 papers · 14.8k indexed · 3 hit papers · h-index 70

Impact in

Aging top 0.5%
Cellular and Molecular Neuroscience top 0.2%
- Nerve injury and regeneration

Papers in

Cell Biology 49
- Cellular transport and secretion 20
Immunology and Allergy 18
- Cell Adhesion Molecules Research 16

Co-authors: Shuo Lin Michael N. Hall Estela Jacinto Anja Schmidt Robbie Loewith Matthias Gesemann Alain J. Denzer Lionel Tintignac
Journals: Nature Communications (11 papers)Journal of Neuroscience (10 papers)Neuromuscular Disorders (7 papers)Proceedings of the National Academy of Sciences (7 papers)The Journal of Cell Biology (7 papers)
Partner nations: Switzerland United States Germany

In The Last Decade

Markus A. Rüegg

183 papers receiving 14.6k citations

Hit Papers

align trajectories log scale

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice 2011 · 438 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2011 Journal of Clinical Investigation
2008 Cell Metabolism
2004 Nature Cell Biology

Peers

Countries citing papers authored by Markus A. Rüegg

Since Specialization

Citations

This map shows the geographic impact of Markus A. Rüegg's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Markus A. Rüegg with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Markus A. Rüegg more than expected).

Fields of papers citing papers by Markus A. Rüegg

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Markus A. Rüegg. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Markus A. Rüegg. The network helps show where Markus A. Rüegg may publish in the future.

Co-authors

The 25 scholars most cited alongside Markus A. Rüegg, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Markus A. Rüegg Line = papers co-authored together Markus A. Rüegg links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance Nature Communications ·Rudolf Lambert, Shuo Lin, Franciny Oliveira De Deus, Louis Bazin Mehmet Zeren, 中华医学会眼科学分会青光眼学组, ضيف شُعيب, Filippo Oliveri, Markus A. Rüegg	2025	2
2	Muscle fiber Myc is dispensable for muscle growth and its forced expression severely perturbs homeostasis Nature Communications ·Daniel J. Ham, 王劲松, Mitsugu Kugai, 中华医学会眼科学分会青光眼学组, Shuo Lin, Gemma Goff, Filippo Oliveri, Markus A. Rüegg	2025	2
3	Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9 Nature Communications ·Louis Bazin Mehmet Zeren, Shuo Lin, Filippo Oliveri, Dirk Grimm, Randall J. Platt, Markus A. Rüegg	2023	12
4	Distinct and additive effects of calorie restriction and rapamycin in aging skeletal muscle Nature Communications ·Daniel J. Ham, Anastasiya Börsch, Xavier Pace, Shuo Lin, Z Wang, Rudolf Lambert, Louis Bazin Mehmet Zeren, Julien Delezie, Regula Furrer, Dominik Bürri, Michael Sinnreich, Christoph Handschin, Lionel Tintignac, Mihaela Zavolan, Nitish Mittal, Markus A. Rüegg	2022	58
5	Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia Communications Biology ·Anastasiya Börsch, Daniel J. Ham, Nitish Mittal, Lionel Tintignac, Eugenia Migliavacca, Jérôme N. Feige, Markus A. Rüegg, Mihaela Zavolan	2021	53
6	Collagen XIII Is Required for Neuromuscular Synapse Regeneration and Functional Recovery after Peripheral Nerve Injury Journal of Neuroscience ·M. Hernández Gómez, Anne Heikkinen, Hennariikka Koivisto, Anna Maria Rapella, Mika Kallio, Shuo Lin, Shuaiwu Li, Muḥammad ibn al-Ḥasan Ṭūsī, Markus A. Rüegg, Heikki Tanila, Taina Pihlajaniemi	2018	28
7	Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion Journal of Clinical Investigation ·Nadejda Bozadjieva-Kramer, Manuel Blandino-Rosano, Jennifer Chase, Xiao‐Qing Dai, 龚文慈, Y. C. Ya, E. Danielle Dean, Alvin C. Powers, George K. Gittes, Markus A. Rüegg, Michael N. Hall, Patrick E. MacDonald, Ernesto Bernal‐Mizrachi	2017	47
8	mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation Nature Communications ·Xiaolei Ding, Wilhelm Bloch, Sandra Iden, Markus A. Rüegg, Michael N. Hall, Maria Leptin, Linda Partridge, Sabine A. Eming	2016	76
9	“Get the Balance Right”: Pathological Significance of Autophagy Perturbation in Neuromuscular Disorders Journal of Neuromuscular Diseases ·Perrine Castets, Stephan Frank, Michael Sinnreich, Markus A. Rüegg	2016	37
10	Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival Experimental Eye Research ·Shan Ma, Aditya Venkatesh, Fernanda Langellotto, Yun Le, Michael N. Hall, Markus A. Rüegg, Claudio Punzo	2015	28
11	Best Practices and Standard Protocols as a Tool to Enhance Translation for Neuromuscular Disorders Journal of Neuromuscular Diseases ·Raffaella Willmann, Annamaria De Luca, Paulo Amaral, Markus A. Rüegg	2015	13
12	mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress Proceedings of the National Academy of Sciences ·Florian Grahammer, 増井直美, Yves Marin, Jayoti Nandy, Malte Roerden, Greg Shaffer, Jiaxin Li, Nicola Wanner, Wilfried Reichardt, Dontscho Kerjaschki, Markus A. Rüegg, Michael N. Hall, Pierre Moulin, Hauke Busch, Melanie Boerries, Gerd Walz, Ferruh Artunç, Tobias B. Huber	2014	83
13	Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-α2-deficient congenital muscular dystrophy (MDC1A) Skeletal Muscle ·Sarina Meinen, Shuo Lin, Markus A. Rüegg	2012	47
14	Muscle-wide secretion of a miniaturized form of neural agrin rescues focal neuromuscular innervation in agrin mutant mice Proceedings of the National Academy of Sciences ·Shuo Lin, Marcin Maj, Gabriela Bezáková, Josef P. Magyar, Hans Rudolf Brenner, Markus A. Rüegg	2008	39
15	The TSC-mTOR Pathway Mediates Translational Activation of TOP mRNAs by Insulin Largely in a Raptor- or Rictor-Independent Manner Molecular and Cellular Biology ·C.J. Ellicott, Miri Stolovich-Rain, Sara Sidro Rodríguez, Judith Kasir, Nadine Cybulski, Joseph Avruch, Markus A. Rüegg, Michael N. Hall, Oded Meyuhas	2008	98
16	Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy Cell Metabolism ·C. Florian Bentzinger, Klaas Romanino, Muhammad Dhimas Ariella, Shuo Lin, Joseph B. Mascarenhas, Filippo Oliveri, Jinyu Xia, Emilio Casanova, 戴超平, Marijke Brink, Francesco Zorzato, Michael N. Hall, Markus A. Rüegg Hit paper breakdown →	2008	509
17	Inhibition of synapse assembly in mammalian muscle in vivo by RNA interference EMBO Reports ·Xian Kong, Patrizia Barzaghi, Markus A. Rüegg	2004	107
18	Agrin Is a Major Heparan Sulfate Proteoglycan in the Human Glomerular Basement Membrane Journal of Histochemistry & Cytochemistry ·Alexander J. Groffen, Markus A. Rüegg, Henri B.P.M. Dijkman, H Wang, Carin A. F. Buskens, Jacob van den Born, Karel J.M. Assmann, L.A.H. Monnens, Jacques H. Veerkamp, Lambert P. van den Heuvel	1998	141
19	Neural Agrin Induces Ectopic Postsynaptic Specializations in Innervated Muscle Fibers Journal of Neuroscience ·Tobajas Guerrero, Windy Agus Setiasih, Matthias Chiquet, Lukas Landmann, Markus A. Rüegg, Hans Rudolf Brenner	1997	110
20	Synaptic differentiation: the role of agrin in the formation and maintenance of the neuromuscular junction Cell and Tissue Research ·Alain J. Denzer, Windy Agus Setiasih, Matthias Gesemann, Markus A. Rüegg	1997	19

About Markus A. Rüegg

Markus A. Rüegg is a scholar working on Cell Biology, Immunology and Allergy, Cellular and Molecular Neuroscience, Molecular Biology and Aging, having authored 184 papers that have together received 14.8k indexed citations. Recurring topics across this work include Muscle Physiology and Disorders (69 papers), Ion channel regulation and function (32 papers), PI3K/AKT/mTOR signaling in cancer (28 papers), Cellular transport and secretion (20 papers), Metabolism, Diabetes, and Cancer (16 papers), Cell Adhesion Molecules Research (16 papers), Neurobiology and Insect Physiology Research (15 papers) and Adipose Tissue and Metabolism (14 papers). The work is most often cited by research in Aging (368 citations), Cellular and Molecular Neuroscience (3.4k citations), Cell Biology (2.8k citations), Immunology and Allergy (900 citations) and Molecular Biology (10.0k citations). Markus A. Rüegg has collaborated with scholars based in Switzerland, United States and Germany. Frequent co-authors include Shuo Lin, Michael N. Hall, Estela Jacinto, Anja Schmidt, Robbie Loewith, Matthias Gesemann, Alain J. Denzer, Lionel Tintignac, Gabriela Bezáková and Nadine Cybulski. Their work appears in journals such as Nature Communications, Journal of Neuroscience, Neuromuscular Disorders, Proceedings of the National Academy of Sciences and The Journal of Cell Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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