Dirk Grimm

14.2k total citations · 3 hit papers
150 papers, 9.6k citations indexed

About

Dirk Grimm is a scholar working on Molecular Biology, Genetics and Epidemiology. According to data from OpenAlex, Dirk Grimm has authored 150 papers receiving a total of 9.6k indexed citations (citations by other indexed papers that have themselves been cited), including 110 papers in Molecular Biology, 83 papers in Genetics and 24 papers in Epidemiology. Recurrent topics in Dirk Grimm's work include Virus-based gene therapy research (82 papers), RNA Interference and Gene Delivery (55 papers) and CRISPR and Genetic Engineering (50 papers). Dirk Grimm is often cited by papers focused on Virus-based gene therapy research (82 papers), RNA Interference and Gene Delivery (55 papers) and CRISPR and Genetic Engineering (50 papers). Dirk Grimm collaborates with scholars based in Germany, United States and France. Dirk Grimm's co-authors include Mark A. Kay, Theresa A. Storm, Jürgen A. Kleinschmidt, Kusum Pandey, Corrine R. Davis, Karola Rittner, Andrea Kern, Felix H. Salazar, Konrad L. Streetz and Patricia L. Marion and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Dirk Grimm

142 papers receiving 9.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

2006 1.3k citations Dirk Grimm, Theresa A. Storm et al. Nature profile →
Novel Tools for Production and Purification of Recombinant Adenoassociated Virus Vectors

1998 581 citations Dirk Grimm et al. Human Gene Therapy profile →
In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses

2008 537 citations Dirk Grimm, Joyce Lee et al. Journal of Virology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Dirk Grimm Germany	49	7.0k	4.2k	1.1k	1.0k	868	150	9.6k
Wei Wu China	45	9.1k 1.3×	2.3k 0.6×	717 0.7×	705 0.7×	354 0.4×	177	12.5k
Danny Huylebroeck Belgium	58	8.3k 1.2×	1.3k 0.3×	983 0.9×	1.1k 1.1×	407 0.5×	163	11.7k
Izumu Saito Japan	47	4.7k 0.7×	2.5k 0.6×	2.3k 2.1×	441 0.4×	452 0.5×	155	8.9k
Manfred Gossen Germany	37	9.5k 1.4×	4.2k 1.0×	588 0.5×	647 0.6×	283 0.3×	90	12.5k
Ken‐ichi Yamamura Japan	27	4.3k 0.6×	1.9k 0.5×	975 0.9×	337 0.3×	495 0.6×	89	7.2k
Choji Taya Japan	35	3.8k 0.5×	927 0.2×	754 0.7×	412 0.4×	561 0.6×	71	7.2k
Ulrich Rüther Germany	55	8.5k 1.2×	3.2k 0.8×	659 0.6×	1.3k 1.3×	147 0.2×	136	11.8k
Hiroyuki Miyoshi Japan	44	6.5k 0.9×	2.3k 0.5×	445 0.4×	682 0.7×	292 0.3×	103	9.1k
Ophir Shalem United States	21	11.6k 1.7×	2.3k 0.5×	638 0.6×	745 0.7×	282 0.3×	42	13.1k
Nathan D. Lawson United States	55	10.2k 1.5×	1.5k 0.4×	649 0.6×	2.0k 2.0×	250 0.3×	95	13.7k

Countries citing papers authored by Dirk Grimm

Since Specialization

Citations

This map shows the geographic impact of Dirk Grimm's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dirk Grimm with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dirk Grimm more than expected).

Fields of papers citing papers by Dirk Grimm

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dirk Grimm. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dirk Grimm. The network helps show where Dirk Grimm may publish in the future.

Co-authorship network of co-authors of Dirk Grimm

This figure shows the co-authorship network connecting the top 25 collaborators of Dirk Grimm. A scholar is included among the top collaborators of Dirk Grimm based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dirk Grimm. Dirk Grimm is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Schröder, Lena, Susanne Hille, Anca Remes, et al.. (2025). Directed Evolution of AAV9 for Efficient Gene Expression in Cardiomyocytes In Vitro and In Vivo. Human Gene Therapy. 36(3-4). 101–115. 1 indexed citations

Schildgen, Oliver, Jianming Qiu, Mario Mietzsch, et al.. (2025). Twenty years of human bocavirus research: from an unculturable virus of unclear pathogenicity to a culturable human pathogen and gene therapy vector candidate. Clinical Microbiology Reviews. 38(4). e0017324–e0017324.

Qu, Bingqian, Florian A. Lempp, Zhenfeng Zhang, et al.. (2024). An hepatitis B and D virus infection model using human pluripotent stem cell-derived hepatocytes. EMBO Reports. 25(10). 4311–4336.

Liu, Jixin, et al.. (2023). Progress in Bioengineering of Myotropic Adeno-Associated Viral Gene Therapy Vectors. Human Gene Therapy. 34(9-10). 350–364. 13 indexed citations

Mosqueira, Matías, Enrico Domenico Lemma, Kleopatra Rapti, et al.. (2023). Membrane remodelling triggers maturation of excitation–contraction coupling in 3D-shaped human-induced pluripotent stem cell-derived cardiomyocytes. Basic Research in Cardiology. 118(1). 13–13. 6 indexed citations

Grosch, Markus, Kleopatra Rapti, Anne-Maud Ferreira, et al.. (2023). Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy. Nature Communications. 14(1). 3714–3714. 25 indexed citations

Chondronasiou, Dafni, Lluc Mosteiro, Jaime Martínez de Villarreal, et al.. (2022). Natural killer cells act as an extrinsic barrier for in vivo reprogramming. Development. 149(8). 18 indexed citations

Barayeu, Uladzimir, Thomas Klintzsch, Dirk Grimm, et al.. (2022). Methane formation driven by reactive oxygen species across all living organisms. Nature. 603(7901). 482–487. 120 indexed citations

Stanifer, Megan L., Sarah R. Leist, Bettina Stolp, et al.. (2022). Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV/RNAi expression vectors. Molecular Therapy. 30(5). 2005–2023. 14 indexed citations

10.

Marichal‐Gallardo, Pavel, Kathleen Börner, Michael Pieler, et al.. (2021). Single-Use Capture Purification of Adeno-Associated Viral Gene Transfer Vectors by Membrane-Based Steric Exclusion Chromatography. Human Gene Therapy. 32(17-18). 959–974. 33 indexed citations

11.

Cheng, Ming, Laura Dietz, Yi Gong, et al.. (2021). Neutralizing Antibody Evasion and Transduction with Purified Extracellular Vesicle-Enveloped Adeno-Associated Virus Vectors. Human Gene Therapy. 32(23-24). 1457–1470. 24 indexed citations

12.

Weinmann, Jonas, Warut Tulalamba, Anca Remes, et al.. (2020). Identification of a myotropic AAV by massively parallel in vivo evaluation of barcoded capsid variants. Nature Communications. 11(1). 5432–5432. 168 indexed citations

13.

Hoffmann, Mareike D., Julius Upmeier zu Belzen, Zander Harteveld, et al.. (2020). Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein. Nucleic Acids Research. 49(5). e29–e29. 33 indexed citations

14.

Hoffmann, Mareike D., Sabine Aschenbrenner, Stefanie Große, et al.. (2019). Cell-specific CRISPR–Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins. Nucleic Acids Research. 47(13). e75–e75. 85 indexed citations

15.

Große, Stefanie, et al.. (2018). Impact of the Assembly-Activating Protein on Molecular Evolution of Synthetic Adeno-Associated Virus Capsids. Human Gene Therapy. 30(1). 21–35. 11 indexed citations

16.

Senís, Elena, Lluc Mosteiro, Stefan Wilkening, et al.. (2018). AAV vector-mediated in vivo reprogramming into pluripotency. Nature Communications. 9(1). 2651–2651. 41 indexed citations

17.

Grimm, Dirk & Hildegard Büning. (2017). Small But Increasingly Mighty: Latest Advances in AAV Vector Research, Design, and Evolution. Human Gene Therapy. 28(11). 1075–1086. 93 indexed citations

18.

Amoasii, Leonela, Chengzu Long, Hui Li, et al.. (2017). Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy. Science Translational Medicine. 9(418). 197 indexed citations

19.

Große, Stefanie, et al.. (2015). Alleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys. Proceedings of the National Academy of Sciences. 112(30). E4007–16. 31 indexed citations

20.

Grimm, Dirk, Joyce Lee, Tushar Desai, et al.. (2008). In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses. Journal of Virology. 82(12). 5887–5911. 537 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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