Marc Hummersone

2.2k citations

22 papers · 1.0k indexed · h-index 14

Co-authors: Mark Frigerio Karl J. Hale Soraya Manaviazar Keith Menear Xiaoling Cockcroft Laurent Rigoreau Gurpreet Singh Bhatia Nicholas C.K. Valerie
Topics: Cancer therapeutics and mechanisms (7 papers)DNA Repair Mechanisms (6 papers)Glioma Diagnosis and Treatment (6 papers)
Cited by: Biotechnology Organic Chemistry Genetics
Journals: Cancer Research Journal of Medicinal Chemistry Organic Letters
Partner nations: United Kingdom United States China

In The Last Decade

Marc Hummersone

22 papers receiving 1.0k citations

Peers

Countries citing papers authored by Marc Hummersone

Since Specialization

Citations

This map shows the geographic impact of Marc Hummersone's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Marc Hummersone with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Marc Hummersone more than expected).

Fields of papers citing papers by Marc Hummersone

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Marc Hummersone. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Marc Hummersone. The network helps show where Marc Hummersone may publish in the future.

Co-authorship network of co-authors of Marc Hummersone

This figure shows the co-authorship network connecting the top 25 collaborators of Marc Hummersone. A scholar is included among the top collaborators of Marc Hummersone based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Marc Hummersone. Marc Hummersone is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Synthesis and growth-inhibitory activities of imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamides related to the anti-tumour drug temozolomide, with appended silicon, benzyl and heteromethyl groups at the 3-position 2018 ·MedChemComm ·(unknown),Marc Hummersone,Tracey D. Bradshaw,Jihong Zhang,Christopher J. Moody,(unknown),(unknown),William Lewis,Richard T. Wheelhouse,Malcolm F. G. Stevens	5
2	Antitumor imidazo[5,1-d]-1,2,3,5-tetrazines: compounds modified at the 3-position overcome resistance in human glioblastoma cell lines 2016 ·MedChemComm ·(unknown),Jihong Zhang,Marc Hummersone,Charles S. Matthews,Mark Frigerio,Tracey D. Bradshaw,Malcolm F. G. Stevens	16
3	N3-Substituted Temozolomide Analogs Overcome Methylguanine-DNA Methyltransferase and Mismatch Repair Precipitating Apoptotic and Autophagic Cancer Cell Death 2014 ·Oncology ·Jihong Zhang,Marc Hummersone,Charles S. Matthews,Malcolm F. G. Stevens,Tracey D. Bradshaw	24
4	Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities 2014 ·Journal of Experimental & Clinical Cancer Research ·Angela Rizzo,Sara Iachettini,Pasquale Zizza,Chiara Cingolani,Manuela Porru,Simona Artuso,Malcolm F. G. Stevens,Marc Hummersone,Annamaria Biroccio,Erica Salvati,Carlo Leonetti	33
5	Optimization of potent and selective dual mTORC1 and mTORC2 inhibitors: The discovery of AZD8055 and AZD2014 2013 ·Bioorganic & Medicinal Chemistry Letters ·Kurt G. Pike,Karine Malagu,Marc Hummersone,Keith Menear,(unknown),Sylvie Gomez,Niall M.B. Martin,Linette Ruston,(unknown),Martin Pass	166
6	1-Substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-ones Endowed with Dual DNA-PK/PI3-K Inhibitory Activity 2013 ·Journal of Medicinal Chemistry ·Céline Cano,(unknown),Chris Bailey,Julia Bárdos,Nicola J. Curtin,Mark Frigerio,Bernard T. Golding,Ian R. Hardcastle,Marc Hummersone,Keith Menear,David R. Newell,Caroline J. Richardson,(unknown),Graeme C.M. Smith,Pia Thömmes,Attilla Ting,Roger J. Griffin	42
7	On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts 2013 ·Journal of Experimental & Clinical Cancer Research ·Sara Iachettini,Malcolm F. G. Stevens,Mark Frigerio,Marc Hummersone,Ian Hutchinson,Thomas P. Garner,Mark S. Searle,David W. Wilson,Manoj Munde,Rupesh Nanjunda,Carmen D’Angelo,Pasquale Zizza,Angela Rizzo,Chiara Cingolani,Federica de Cicco,Manuela Porru,Maurizio D’Incalci,Carlo Leonetti,Annamaria Biroccio,Erica Salvati	26
8	Antitumour imidazotetrazines. Synthesis and chemistry of 4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide (nor-temozolomide): an intermediate for the preparation of the antitumour drug temozolomide and analogues, avoiding the use of isocyanates 2012 ·MedChemComm ·(unknown),Malcolm F. G. Stevens,Marc Hummersone	8
9	Abstract 917: AZD2014, a dual mTORC1 and mTORC2 inhibitor is differentiated from allosteric inhibitors of mTORC1 in ER+ breast cancer 2012 ·Cancer Research ·Sylvie M. Guichard,Zoë Howard,Dan Heathcote,Mark J. Roth,Gareth Hughes,Jon Curwen,(unknown),Armelle Logié,Sarah V. Holt,Christine M. Chresta,Barry R. Davies,Karine Malagu,Marc Hummersone,(unknown),Stephen Green,Martin Pass	16
10	Certain Imidazotetrazines Escape O6-Methylguanine-DNA Methyltransferase and Mismatch Repair 2011 ·Oncology ·Jihong Zhang,Malcolm F. G. Stevens,Marc Hummersone,Srinivasan Madhusudan,Charles A. Laughton,Tracey D. Bradshaw	24
11	176 N3-Substituted temozolomide analogs overcome methylguanine DNA methyltransferase and mismatch repair 2010 ·European Journal of Cancer Supplements ·Tracey D. Bradshaw,Marc Hummersone,John A. Hartley,(unknown),(unknown)	1
12	Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion 2009 ·Molecular Cancer Therapeutics ·Sarah E. Golding,Elizabeth Rosenberg,Nicholas C.K. Valerie,Isa M. Hussaini,Mark Frigerio,Xiaoling Cockcroft,(unknown),Marc Hummersone,Laurent Rigoreau,Keith Menear,Mark J. O’Connor,Lawrence F. Povirk,Timothy Van Meter,Kristoffer Valerie	285
13	Abstract A143: Novel temozolomide analog may overcome MGMT and MMR 2009 ·Molecular Cancer Therapeutics ·Jihong Zhang,Malcolm F. G. Stevens,(unknown),Marc Hummersone,Charles A. Laughton,Tracey D. Bradshaw	2
14	Identification of potent water-soluble DNA-dependent protein kinase (DNA-PK) inhibitors using a small-molecule library approach [abstract] 2008 ·Cancer Research ·(unknown),Mark R. Albertella,Céline Cano,Nicola J. Curtin,Mark Frigerio,Bernard T. Golding,(unknown),Ian R. Hardcastle,Marc Hummersone,Keith Menear,David R. Newell,(unknown),Caroline J. Richardson,Laurent Rigoreau,(unknown),Graeme C.M. Smith,Roger J. Griffin	3
15	Pyranone, Thiopyranone, and Pyridone Inhibitors of Phosphatidylinositol 3-Kinase Related Kinases. Structure−Activity Relationships for DNA-Dependent Protein Kinase Inhibition, and Identification of the First Potent and Selective Inhibitor of the Ataxia Telangiectasia Mutated Kinase 2007 ·Journal of Medicinal Chemistry ·Jonathan J. Hollick,Laurent Rigoreau,Céline Cano,Xiaoling Cockcroft,Nicola J. Curtin,Mark Frigerio,Bernard T. Golding,(unknown),Ian R. Hardcastle,Ian Hickson,Marc Hummersone,Keith Menear,Niall M.B. Martin,Ian Matthews,David R. Newell,(unknown),Caroline J. Richardson,Graeme C.M. Smith,Roger J. Griffin	61
16	Synthesis of a Simplified Bryostatin C-Ring Analogue That Binds to the CRD2 of Human PKC-α and Construction of a Novel BC-Analogue by an Unusual Julia Olefination Process 2003 ·Organic Letters ·Karl J. Hale,Mark Frigerio,Soraya Manaviazar,Marc Hummersone,Ian J. FILLINGHAM,(unknown),Christian Damblon,Andreas Gescher,Gordon C. K. Roberts	13
17	The chemistry and biology of the bryostatin antitumour macrolides 2002 ·Natural Product Reports ·Karl J. Hale,Marc Hummersone,Soraya Manaviazar,Mark Frigerio	149
18	The Chemistry and Biology of the Bryostatin Antitumor Macrolides 2002 ·ChemInform ·Karl J. Hale,Marc Hummersone,Soraya Manaviazar,Mark Frigerio	1
19	Control of Olefin Geometry in the Bryostatin B-Ring through Exploitation of a C₂-Symmetry Breaking Tactic and a Smith−Tietze Coupling Reaction 2000 ·Organic Letters ·Karl J. Hale,Marc Hummersone,Gurpreet Singh Bhatia	34
20	Synthetic studies on the A83586C and bryostatin antitumor macrolides and the monamycin antibiotics 2000 ·Pure and Applied Chemistry ·Karl J. Hale,Marc Hummersone,Jiaqiang Cai,Soraya Manaviazar,Gurpreet Singh Bhatia,(unknown),Mark Frigerio,(unknown),(unknown),(unknown),(unknown)	11

About Marc Hummersone

Marc Hummersone is a scholar working on Toxicology, Genetics and Oncology, having authored 22 papers that have together received 1.0k indexed citations. Recurring topics across this work include Cancer therapeutics and mechanisms (7 papers), DNA Repair Mechanisms (6 papers) and Glioma Diagnosis and Treatment (6 papers). The work is most often cited by research in Biotechnology (110 citations), Organic Chemistry (323 citations) and Genetics (105 citations). Marc Hummersone has collaborated with scholars based in United Kingdom, United States and China. Frequent co-authors include Mark Frigerio, Karl J. Hale, Soraya Manaviazar, Keith Menear, Xiaoling Cockcroft, Laurent Rigoreau, Gurpreet Singh Bhatia, Nicholas C.K. Valerie, Lawrence F. Povirk and Sarah E. Golding. Their work appears in journals such as Cancer Research, Journal of Medicinal Chemistry and Organic Letters.

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