Larry Feldberg

1.4k citations

25 papers · 1.2k indexed · h-index 19

Impact in

Organic Chemistry top 5%
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Quinazolinone synthesis and applications
Biotechnology top 5%
- Marine Sponges and Natural Products

Papers in

Organic Chemistry 16
- Quinazolinone synthesis and applications 7
- Synthesis and biological activity 5
Biotechnology 4
- Marine Sponges and Natural Products 4

Co-authors: Robert Mallon Irwin Hollander Christoph M. Dehnhardt Aranapakam M. Venkatesan Zecheng Chen Semiramis Ayral‐Kaloustian Judy Lucas Efren Delos Santos
Journals: Bioorganic & Medicinal Chemistry Letters (10 papers)Journal of Medicinal Chemistry (5 papers)Molecular Cancer Therapeutics (2 papers)Clinical Cancer Research (2 papers)Organic Letters (1 paper)
Partner nations: United States Canada Netherlands

In The Last Decade

Larry Feldberg

24 papers receiving 1.1k citations

Peers

Countries citing papers authored by Larry Feldberg

Since Specialization

Citations

This map shows the geographic impact of Larry Feldberg's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Larry Feldberg with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Larry Feldberg more than expected).

Fields of papers citing papers by Larry Feldberg

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Larry Feldberg. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Larry Feldberg. The network helps show where Larry Feldberg may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Larry Feldberg, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Larry Feldberg Line = papers co-authored together Larry Feldberg links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Antitumor Efficacy of PKI-587, a Highly Potent Dual PI3K/mTOR Kinase Inhibitor Clinical Cancer Research ·Robert Mallon, Larry Feldberg, Judy Lucas, Indrasish Ray Chaudhuri, Christoph M. Dehnhardt, Efren Delos Santos, Zecheng Chen, Osvaldo dos Santos, Semiramis Ayral‐Kaloustian, Aranapakam M. Venkatesan, Irwin Hollander	2011	145
2	Identification of 2-oxatriazines as highly potent pan-PI3K/mTOR dual inhibitors Bioorganic & Medicinal Chemistry Letters ·Christoph M. Dehnhardt, Aranapakam M. Venkatesan, Zecheng Chen, Lovel Tw, Semiramis Ayral‐Kaloustian, Natasja Brooijmans, Ker Yu, Irwin Hollander, Larry Feldberg, Judy Lucas, Robert Mallon	2011	30
3	Antitumor Efficacy Profile of PKI-402, a Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor Molecular Cancer Therapeutics ·Robert Mallon, Irwin Hollander, Larry Feldberg, Judy Lucas, Veronica Soloveva, Aranapakam M. Venkatesan, Christoph M. Dehnhardt, Efren Delos Santos, Zecheng Chen, Osvaldo dos Santos, Semiramis Ayral‐Kaloustian, Jay Gibbons	2010	52
4	B-Raf kinase inhibitors: Hit enrichment through scaffold hopping Bioorganic & Medicinal Chemistry Letters ·Ariamala Gopalsamy, Mengxiao Shi, Yongbo Hu, Frederick Lee, Larry Feldberg, Zhangjie Li, S.A. Kondratyeva, Karen Collins, Donald Wojciechowicz, Robert Mallon	2010	18
5	PKI-179: An orally efficacious dual phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibitor Bioorganic & Medicinal Chemistry Letters ·Aranapakam M. Venkatesan, Zecheng Chen, Osvaldo dos Santos, Christoph M. Dehnhardt, Efren Delos Santos, Semiramis Ayral‐Kaloustian, Robert Mallon, Irwin Hollander, Larry Feldberg, Judy Lucas, Ker Yu, Indrasish Ray Chaudhuri, Tarek S. Mansour	2010	59
6	Synthesis of Phosphatidylinositol 3-Kinase (PI3K) Inhibitory Analogues of the Sponge Meroterpenoid Liphagal Journal of Medicinal Chemistry ·Albán R. Pereira, Wendy K. Strangman, Frédéric Marion, Larry Feldberg, Deborah M. Roll, Robert Mallon, Irwin Hollander, Raymond J. Andersen	2010	34
7	Novel purine and pyrazolo[3,4-d]pyrimidine inhibitors of PI3 kinase-α: Hit to lead studies Bioorganic & Medicinal Chemistry Letters ·A. Gilbert, Paweł Nowak, Natasja Brooijmans, Matthew G. Bursavich, Christoph M. Dehnhardt, Efren Delos Santos, Larry Feldberg, Irwin Hollander, Stephen Kim, Sabrina Lombardi, Kaapjoo Park, Aranapakam M. Venkatesan, Robert Mallon	2009	32
8	Novel imidazolopyrimidines as dual PI3-Kinase/mTOR inhibitors Bioorganic & Medicinal Chemistry Letters ·Aranapakam M. Venkatesan, Christoph M. Dehnhardt, Zecheng Chen, Efren Delos Santos, Osvaldo dos Santos, Matthew G. Bursavich, A. Gilbert, John W. Ellingboe, Semiramis Ayral‐Kaloustian, Gulnaz Khafizova, Natasja Brooijmans, Robert Mallon, Irwin Hollander, Larry Feldberg, Judy Lucas, Ker Yu, Jay Gibbons, Robert T. Abraham, Tarek S. Mansour	2009	23
9	Hit to lead optimization of pyrazolo[1,5-a]pyrimidines as B-Raf kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Ariamala Gopalsamy, Moh Faisal Faris, Mengxiao Shi, Dan Berger, Yongbo Hu, Frederick Lee, Larry Feldberg, Zhangjie Li, S.A. Kondratyeva, Karen Collins, Donald Wojciechowicz, Robert Mallon	2009	16
10	Scalarane-Based Sesterterpenoid RCE-Protease Inhibitors Isolated from the Indonesian Marine Sponge Carteriospongia foliascens Journal of Natural Products ·David E. Williams, Irwin Hollander, Larry Feldberg, Zhangjie Li, Robert Mallon, Akbar Tahir, Rob W. M. van Soest, Raymond J. Andersen	2009	24
11	Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Dan M. Berger, Virangna Taneja, Minu Dutia, Dennis Powell, Moh Faisal Faris, Ariamala Gopalsamy, Jeremy I. Levin, Kyung‐Hee Kim, Weixin Xu, James E. Wilhelm, Yongbo Hu, Karen Collins, Larry Feldberg, S.A. Kondratyeva, Zhangjie Li, Donald Wojciechowicz, Robert Mallon	2009	32
12	Lead Optimization of N-3-Substituted 7-Morpholinotriazolopyrimidines as Dual Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of PKI-402 Journal of Medicinal Chemistry ·Christoph M. Dehnhardt, Aranapakam M. Venkatesan, Efren Delos Santos, Zecheng Chen, Osvaldo dos Santos, Semiramis Ayral‐Kaloustian, Natasja Brooijmans, Robert Mallon, Irwin Hollander, Larry Feldberg, Judy Lucas, Indrasish Ray Chaudhuri, Ker Yu, Jay Gibbons, Robert T. Abraham, Tarek S. Mansour	2009	66
13	Identification of pyrazolo[1,5-a]pyrimidine-3-carboxylates as B-Raf kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Ariamala Gopalsamy, Moh Faisal Faris, Yongbo Hu, Frederick Lee, Larry Feldberg, Zhangjie Li, S.A. Kondratyeva, Karen Collins, Donald Wojciechowicz, Robert Mallon	2009	40
14	4-Anilino-7-alkenylquinoline-3-carbonitriles as potent MEK1 kinase inhibitors Bioorganic & Medicinal Chemistry ·Dan M. Berger, Minu Dutia, Dennis Powell, ASRUN ASRUN, Virangna Taneja, Robert Mallon, Donald Wojciechowicz, S.A. Kondratyeva, Larry Feldberg, Karen Collins, Indrasish Ray Chaudhuri	2008	16
15	Liphagal, a new meroterpenoid from the Caribbean sponge Aka coralliphaga that shows potent and selective inhibition of P13 kinase alpha. Clinical Cancer Research ·Irwin Hollander, Frédéric Marion, David E. Williams, Robert Mallon, 懐子十河, Deborah M. Roll, Larry Feldberg, R.W.M. van Soest, Raymond J. Andersen	2006	0
16	A Directly Labeled TR-FRET Assay for Monitoring Phosphoinositide-3-Kinase Activity Combinatorial Chemistry & High Throughput Screening ·Xiaoke Yang, Gordon Park Stevenson, Larry Feldberg, Steven C. Kim, Michael Bowman, Irwin Hollander, Robert Mallon, Stanley F. Wolf	2006	10
17	Synthesis and evaluation of 4-Anilino-6,7-dialkoxy-3-quinolinecarbonitriles as inhibitors of kinases of the Ras-MAPK signaling cascade Bioorganic & Medicinal Chemistry Letters ·Dan Berger, Minu Dutia, Dennis Powell, Biqi Wu, Allan Wissner, Diane H. Boschelli, M. Brawner Floyd, Nan Zhang, Virangna Taneja, Jeremy I. Levin, Xuemei Du, Donald Wojciechowicz, Carolyn Discafani, Constance Kohler, Steven C. Kim, Larry Feldberg, Karen Collins, Robert Mallon	2003	25
18	MEK (MAPKK) inhibitors. Part 2: structure–activity relationships of 4-anilino-3-cyano-6,7-dialkoxyquinolines Bioorganic & Medicinal Chemistry Letters ·Nan Zhang, Biqi Wu, Ceicilia Ceicilia, B Rudzinska, Fei Ye, Dennis Powell, Allan Wissner, Larry Feldberg, Steven C. Kim, Robert Mallon, Anaís Carrillo Salas, Lourdes Toral‐Barza, Constance Kohler	2001	24
19	An Enzyme-Linked Immunosorbent Assay for the Raf/MEK1/MAPK Signaling Cascade Analytical Biochemistry ·Robert Mallon, Larry Feldberg, Steven C. Kim, Karen Collins, Donald Wojciechowicz, Irwin Hollander, Sydney Tomholt, Constance Kohler	2001	23
20	Saccharomyces cerevisiae Exhibits a Sporulation-Specific Temporal Pattern of Transcript Accumulation Molecular and Cellular Biology ·David B. Kaback, Larry Feldberg	1985	34

About Larry Feldberg

Larry Feldberg is a scholar working on Organic Chemistry, Biotechnology, Genetics, Molecular Biology and Pathology and Forensic Medicine, having authored 25 papers that have together received 1.2k indexed citations. Recurring topics across this work include PI3K/AKT/mTOR signaling in cancer (10 papers), Melanoma and MAPK Pathways (9 papers), Quinazolinone synthesis and applications (7 papers), Synthesis and biological activity (5 papers), Marine Sponges and Natural Products (4 papers), Protein Kinase Regulation and GTPase Signaling (4 papers), Chronic Lymphocytic Leukemia Research (4 papers) and Cancer Mechanisms and Therapy (4 papers). The work is most often cited by research in Organic Chemistry (563 citations), Biotechnology (123 citations), Molecular Biology (694 citations), Genetics (102 citations) and Pharmacology (142 citations). Larry Feldberg has collaborated with scholars based in United States, Canada and Netherlands. Frequent co-authors include Robert Mallon, Irwin Hollander, Christoph M. Dehnhardt, Aranapakam M. Venkatesan, Zecheng Chen, Semiramis Ayral‐Kaloustian, Judy Lucas, Efren Delos Santos, Osvaldo dos Santos and Indrasish Ray Chaudhuri. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Molecular Cancer Therapeutics, Clinical Cancer Research and Organic Letters.

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