Charles A. Laughton

10.3k citations

170 papers · 8.3k indexed · 2 hit papers · h-index 45

Co-authors: Modesto Orozco Alberto Pérez Jiřı́ Šponer Thomas E. Cheatham Daniel Svozil Sarah A. Harris Stephen Neidle Yeh‐Chih Kao
Topics: DNA and Nucleic Acid Chemistry (62 papers)Protein Structure and Dynamics (38 papers)RNA and protein synthesis mechanisms (28 papers)
Cited by: Molecular Biology Toxicology Physical and Theoretical Chemistry
Journals: Journal of the American Chemical Society Physical Review Letters Nucleic Acids Research
Partner nations: United Kingdom United States Spain

In The Last Decade

Charles A. Laughton

168 papers receiving 8.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Refinement of the AMBER Force Field for Nucleic Acids: Improving the Description of α/γ Conformers

2007 1.8k citations Alberto Pérez, Charles A. Laughton et al. profile →
Parmbsc1: a refined force field for DNA simulations

2015 822 citations Iván Ivani, Pablo D. Dans et al. Nature Methods profile →

Peers

Countries citing papers authored by Charles A. Laughton

Since Specialization

Citations

This map shows the geographic impact of Charles A. Laughton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Charles A. Laughton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Charles A. Laughton more than expected).

Fields of papers citing papers by Charles A. Laughton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Charles A. Laughton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Charles A. Laughton. The network helps show where Charles A. Laughton may publish in the future.

Co-authorship network of co-authors of Charles A. Laughton

This figure shows the co-authorship network connecting the top 25 collaborators of Charles A. Laughton. A scholar is included among the top collaborators of Charles A. Laughton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Charles A. Laughton. Charles A. Laughton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Interfacial water confers transcription factors with dinucleotide specificity 2025 ·Nature Structural & Molecular Biology ·Ekaterina Morgunova,Gábor Nagy,Yimeng Yin,Fangjie Zhu,Sonali Nayak,(unknown),(unknown),А. Н. Попов,Charles A. Laughton,Helmut Grubmüller,Jussi Taipale	6
2	Optimizing Excipient Properties to Prevent Aggregation in Biopharmaceutical Formulations 2023 ·Journal of Chemical Information and Modeling ·(unknown),James R. Humphrey,Charles A. Laughton,Neil R. Thomas,Jonathan D. Hirst	13
3	Design, Synthesis, and Application of Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the CXC Chemokine Receptor 2 2023 ·Journal of Medicinal Chemistry ·(unknown),(unknown),(unknown),Huw E. L. Williams,Steven J. Charlton,Nicholas D. Holliday,Charles A. Laughton,Shailesh N. Mistry	10
4	Linear Binary Classifier to Predict Bacterial Biofilm Formation on Polyacrylates 2023 ·ACS Applied Materials & Interfaces ·(unknown),Andrew L. Hook,David A. Winkler,Grazziela P. Figueredo,Paul Williams,Charles A. Laughton,Morgan R. Alexander,(unknown),(unknown)	6
5	In Vitro Anticancer Properties of Novel Bis-Triazoles 2022 ·Current Issues in Molecular Biology ·(unknown),Duaa Abuarqoub,Alaa M. Hammad,Md Shahadat Hossan,(unknown),(unknown),Abdallah Y. Naser,Christopher J. Moody,Charles A. Laughton,Tracey D. Bradshaw	5
6	Development of fluorescent peptide G protein‐coupled receptor activation biosensors for NanoBRET characterization of intracellular allosteric modulators 2022 ·The FASEB Journal ·(unknown),Shailesh N. Mistry,Charles A. Laughton,Nicholas D. Holliday	5
7	Development of a series of bis-triazoles as G-quadruplex ligands 2017 ·RSC Advances ·(unknown),Charles A. Laughton,Tracey D. Bradshaw,Christopher J. Moody	15
8	The fitness burden imposed by synthesising quorum sensing signals 2016 ·Scientific Reports ·(unknown),Jean‐Frédéric Dubern,Catharine A. Ortori,Freya Harrison,Nigel Halliday,(unknown),(unknown),Charles A. Laughton,Stephen P. Diggle,Paul Williams,David A. Barrett,Kim R. Hardie	31
9	Parmbsc1: a refined force field for DNA simulationsbreakdown → 2015 ·Nature Methods ·Iván Ivani,Pablo D. Dans,Agnes Noy,Alberto Pérez,Ignacio Faustino,Jürgen Walther,Pau Andrio,Ramón Goñi,Alexandra Balaceanu,Guillem Portella,Federica Battistini,Josep Lluís Gelpí,Carlos González,Michele Vendruscolo,Charles A. Laughton,Sarah A. Harris,David A. Case,Modesto Orozco	822
10	Structure of Mycobacterium tuberculosis thioredoxin in complex with quinol inhibitor PMX464 2010 ·Protein Science ·(unknown),Tracey D. Bradshaw,Charles A. Laughton,Malcolm F. G. Stevens,Jonas Emsley	9
11	The levels of telomere-binding proteins in human tumours and therapeutic implications 2008 ·European Journal of Cancer ·(unknown),Charles A. Laughton	13
12	Structure ofMycobacterium tuberculosisthioredoxin C 2006 ·Acta Crystallographica Section D Biological Crystallography ·(unknown),Manish A. Shah,Paul McEwan,Charles A. Laughton,Malcolm F. G. Stevens,Andrew D. Westwell,Jonas Emsley	14
13	An attempt to define allergen-specific molecular surface features: a bioinformatic approach 2005 ·Bioinformatics ·(unknown),Brian J. Sutton,Fabian Glaser,Charles A. Laughton,(unknown),Herb F. Sewell,Farouk Shakib	33
14	Antitumor benzothiazoles. Frontier molecular orbital analysis predicts bioactivation of 2-(4-aminophenyl)benzothiazoles to reactive intermediates by cytochrome P4501A1Part 23. For part 22 see Ref. 1. 2003 ·Organic & Biomolecular Chemistry ·Sean O’Brien,Helen Browne,Tracey D. Bradshaw,Andrew D. Westwell,Malcolm F. G. Stevens,Charles A. Laughton	47
15	Dynamic model of base pair breathing in a DNA chain with a defect 2001 ·Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics ·Jonathan A. D. Wattis,Sarah A. Harris,(unknown),Charles A. Laughton	16
16	The mechanics of minor groove width variation in DNA, and its implications for the accommodation of ligands 1999 ·Journal of Molecular Biology ·Charles A. Laughton,Ben F. Luisi	24
17	Binding characteristics of seven inhibitors of human aromatase: a site-directed mutagenesis study. 1996 ·PubMed ·Yeh‐Chih Kao,(unknown),Charles A. Laughton,Dandan Zhou,(unknown)	84
18	Molecular dynamics simulation of the DNA triplex d(TC)5 · d(GA)5 · d(C+T)5 1992 ·Journal of Molecular Biology ·Charles A. Laughton,Stephen Neidle	32
19	Molecular-Mechanics Modelling of Drug-DNA Structures; the Effects of Differing Dielectric Treatment on Helix Parameters and Comparison with a Fully Solvated Structural Model 1990 ·Journal of Biomolecular Structure and Dynamics ·Modesto Orozco,Charles A. Laughton,(unknown),Stephen Neidle	52
20	Sterically hindered analogues of diacylglycerols. synthesis, binding to the phorbol ester receptor and metabolism in a549 human lung carcinoma cells 1989 ·International Journal of Cancer ·Charles A. Laughton,Tracey D. Bradshaw,Andreas J. Gescher	4

About Charles A. Laughton

Charles A. Laughton is a scholar working on Molecular Biology, Pharmacology and Archeology, having authored 170 papers that have together received 8.3k indexed citations. Recurring topics across this work include DNA and Nucleic Acid Chemistry (62 papers), Protein Structure and Dynamics (38 papers) and RNA and protein synthesis mechanisms (28 papers). The work is most often cited by research in Molecular Biology (6.5k citations), Toxicology (134 citations) and Physical and Theoretical Chemistry (337 citations). Charles A. Laughton has collaborated with scholars based in United Kingdom, United States and Spain. Frequent co-authors include Modesto Orozco, Alberto Pérez, Jiřı́ Šponer, Thomas E. Cheatham, Daniel Svozil, Sarah A. Harris, Stephen Neidle, Yeh‐Chih Kao, Malcolm F. G. Stevens and George C. Shields. Their work appears in journals such as Journal of the American Chemical Society, Physical Review Letters and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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