Andrew Koff

18.4k citations

103 papers · 15.0k indexed · 6 hit papers · h-index 53

Impact in

Oncology top 0.1%
- Cancer-related Molecular Pathways
Molecular Biology top 0.2%
- Ubiquitin and proteasome pathways
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- DNA Repair Mechanisms

Papers in

Oncology 82
- Cancer-related Molecular Pathways 76
Cell Biology 25
- Microtubule and mitosis dynamics 25

Co-authors: Joan Massagué Kornélia Polyák Hiroaki Kiyokawa Michael J. Solomon James M. Roberts Paul Tempst Hediye Erdjument‐Bromage J. M. Roberts
Journals: Molecular and Cellular Biology (13 papers)Journal of Biological Chemistry (7 papers)Cancer Research (5 papers)Genes & Development (5 papers)Cell Cycle (4 papers)
Partner nations: United States Spain United Kingdom

In The Last Decade

Andrew Koff

103 papers receiving 14.8k citations

Hit Papers

6 papers align trajectories log scale

CDK4/6 Inhibitors: The Mechanism of Action May Not Be as Simple as Once Thought 2018 · 274 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2018 Cancer Cell
1996 Cell
1994 Genes & Development
1994 Cell
1992 Science
1991 Cell

Peers

Countries citing papers authored by Andrew Koff

Since Specialization

Citations

This map shows the geographic impact of Andrew Koff's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andrew Koff with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andrew Koff more than expected).

Fields of papers citing papers by Andrew Koff

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andrew Koff. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andrew Koff. The network helps show where Andrew Koff may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Andrew Koff, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Andrew Koff Line = papers co-authored together Andrew Koff links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A549 in-silico 1.0: A first computational model to simulate cell cycle dependent ion current modulation in the human lung adenocarcinoma PLoS Computational Biology ·Yannick Bousquet, Theresa Rienmüller, Hervais Simo Fhom, Brigitte Pelzmann, 楠原洋之, Klaus Zorn‐Pauly, Wolfgang Schreibmayer, Andrew Koff, Christian Baumgärtner	2021	7
2	ATRX is a regulator of therapy induced senescence in human cells Nature Communications ·Marta Kovatcheva, Will Liao, Mary E. Klein, Nicolas Robine, Heather Geiger, Aimeé M. Crago, Mark A. Dickson, William D. Tap, Samuel Singer, Andrew Koff	2017	62
3	The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer Clinical Cancer Research ·Sergio Marchini, Elizabeth Poynor, Richard R. Barakat, Luca Clivio, Michela Cinquini, Robert Fruscio, Luca Porcu, Cecilia Bussani, Maurizio D’Incalci, Eugenio Erba, Michela Romano, Giorgio Cattoretti, Dionyssios Katsaros, Andrew Koff, Lucio Luzzatto	2012	39
4	p27kip1 Protein Levels Reflect a Nexus of Oncogenic Signaling during Cell Transformation Journal of Biological Chemistry ·Jeffrey Miller, 鄂峻膺, Christoph P. Hofstetter, E. Grimaux, Andrew S. Goldstein, Andrew Koff	2012	8
5	Cyclin D1 and Cdk4 Mediate Development of Neurologically Destructive Oligodendroglioma Cancer Research ·Daniel Ciznadija, Yuhui Liu, Stephanie M. Pyonteck, Eric C. Holland, Andrew Koff	2011	33
6	ZIC1 Overexpression Is Oncogenic in Liposarcoma Cancer Research ·Elliott Brill, Ryan M. Gobble, Christina V. Angeles, Mariana Lagos‐Quintana, Aimeé M. Crago, Erik Tazawa-Goodchild, Penelope DeCarolis, Lei Zhang, Cristina Antonescu, Nicholas D. Socci, Barry S. Taylor, Chris Sander, Andrew Koff, Samuel Singer	2010	39
7	CUL4A Abrogation Augments DNA Damage Response and Protection against Skin Carcinogenesis Molecular Cell ·Liren Liu, Sharrell Lee, Jianxuan Zhang, Sara Peters, Jeffrey Hannah, Yue Zhang, Yan Yin, Andrew Koff, Liang Ma, Pengbo Zhou	2009	156
8	How to decrease p27Kip1 levels during tumor development Cancer Cell ·Andrew Koff	2006	51
9	p27 deficiency desensitizes Rb−/− cells to signals that trigger apoptosis during pituitary tumor development Oncogene ·Carmen Carneiro, Espino Caballero, Ming Hu, David R. Shaffer, 和男風間, Pier Paolo Pandolfi, Carlos Cordon‐Cardo, Andrew Koff	2003	24
10	Rho Activity Can Alter the Translation of p27 mRNA and Is Important for RasV12-induced Transformation in a Manner Dependent on p27 Status Journal of Biological Chemistry ·Anxo Vidal, S. Sean Millard, Jeffrey Miller, Andrew Koff	2002	70
11	Regulatory Role of p27kip1 in the Mouse and Human Testis* Endocrinology ·Tim L. Beumer, Hiroaki Kiyokawa, Hermien L. Roepers‐Gajadien, V. Popov, Tycho Lock, Iris S. Gademan, Derk H. Rutgers, Andrew Koff, Dirk G. de Rooij	1999	82
12	Targeted Disruption of CDK4 Delays Cell Cycle Entry with Enhanced p27 ^Kip1 Activity Molecular and Cellular Biology ·Tateki Tsutsui, Maria Paula Moreira Polido, David S. Moons, Pier Paolo Pandolfi, Kashyap, Andrew Koff, Hiroaki Kiyokawa	1999	328
13	Expression of cyclin D1, but not cyclins E and A, is related to progression in bilharzial bladder cancer. PubMed ·Iman Osman, Howard I. Scher, Zuo‐Feng Zhang, Timothy Soos, Suzanne LaForest, Sanaa Eissa, Hussein Khaled, Andrew Koff, Carlos Cordon‐Cardo	1997	17
14	Enhanced Ribosomal Association of p27Kip1 mRNA Is a Mechanism Contributing to Accumulation during Growth Arrest Journal of Biological Chemistry ·S. Sean Millard, Jie Yan, Hoang M. Nguyen, Michele Pagano, Hiroaki Kiyokawa, Andrew Koff	1997	162
15	Involvement of p27KIP1 in G1 arrest mediated by an anti-epidermal growth factor receptor monoclonal antibody. PubMed ·Tia Dwijayanti, Mark A. Rubin, Zhen Fan, Tony DeBlasio, HIDETSUCU YAMAZAKI, Andrew Koff, John Mendelsohn	1996	186
16	p27KIP1, an inhibitor of cyclin-dependent kinases PubMed ·Andrew Koff, Kornélia Polyák	1995	46
17	Inactivation of a Cdk2 Inhibitor during Interleukin 2-Induced Proliferation of Human T Lymphocytes Molecular and Cellular Biology ·Eduardo Firpo, Andrew Koff, Mark J. Solomon, James M. Roberts	1994	93
18	Cyclins, Cdks, and Cyclin Kinase Inhibitors Cold Spring Harbor Symposia on Quantitative Biology ·James M. Roberts, Andrew Koff, Kornélia Polyák, Eduardo Firpo, Steven Collins, Motoaki Ohtsubo, Joan Massagué	1994	81
19	Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family Cell ·Andrew Koff, Fred Cross, Alfred L. Fisher, Jill M. Schumacher, Dong Sun Park, Michel Philippe, James M. Roberts Hit paper breakdown →	1991	568
20	Domain Structure of the Simian Virus 40 Core Origin of Replication Molecular and Cellular Biology ·Sumitra Deb, A L DeLucia, S. Gianassi, Andrew Koff, P Tegtmeyer	1986	146

About Andrew Koff

Andrew Koff is a scholar working on Oncology, Cell Biology, Molecular Biology, Biotechnology and Cancer Research, having authored 103 papers that have together received 15.0k indexed citations. Recurring topics across this work include Cancer-related Molecular Pathways (76 papers), Epigenetics and DNA Methylation (31 papers), Microtubule and mitosis dynamics (25 papers), Ubiquitin and proteasome pathways (22 papers), DNA Repair Mechanisms (7 papers), Cancer Research and Treatments (7 papers), Advanced Breast Cancer Therapies (6 papers) and RNA modifications and cancer (6 papers). The work is most often cited by research in Oncology (8.7k citations), Molecular Biology (10.2k citations), Cancer Research (2.0k citations), Cell Biology (2.2k citations) and Developmental Neuroscience (414 citations). Andrew Koff has collaborated with scholars based in United States, Spain and United Kingdom. Frequent co-authors include Joan Massagué, Kornélia Polyák, Hiroaki Kiyokawa, Michael J. Solomon, James M. Roberts, Paul Tempst, Hediye Erdjument‐Bromage, J. M. Roberts, Jun‐ya Kato and Joanna Roberts. Their work appears in journals such as Molecular and Cellular Biology, Journal of Biological Chemistry, Cancer Research, Genes & Development and Cell Cycle.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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