Lina M. Obeid

36.4k total citations · 7 hit papers
291 papers, 30.5k citations indexed

About

Lina M. Obeid is a scholar working on Molecular Biology, Cell Biology and Physiology. According to data from OpenAlex, Lina M. Obeid has authored 291 papers receiving a total of 30.5k indexed citations (citations by other indexed papers that have themselves been cited), including 269 papers in Molecular Biology, 96 papers in Cell Biology and 43 papers in Physiology. Recurrent topics in Lina M. Obeid's work include Sphingolipid Metabolism and Signaling (230 papers), Lipid Membrane Structure and Behavior (83 papers) and Endoplasmic Reticulum Stress and Disease (56 papers). Lina M. Obeid is often cited by papers focused on Sphingolipid Metabolism and Signaling (230 papers), Lipid Membrane Structure and Behavior (83 papers) and Endoplasmic Reticulum Stress and Disease (56 papers). Lina M. Obeid collaborates with scholars based in United States, Japan and China. Lina M. Obeid's co-authors include Yusuf A. Hannun, Jacek Bielawski, Alicja Bielawska, Cungui Mao, Thomas D. Mullen, Corinne M. Linardic, Christopher Gault, Tarek A. Taha, Besim Öğretmen and Bin Liu and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Lina M. Obeid

288 papers receiving 30.1k citations

Hit Papers

Principles of bioactive l... 1991 2026 2002 2014 2008 1993 2017 2010 2002 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Principles of bioactive lipid signalling: lessons from sphingolipids
    2008 2.7k citations Yusuf A. Hannun, Lina M. Obeid profile →
  2. Programmed Cell Death Induced by Ceramide
    1993 1.6k citations Lina M. Obeid, Yusuf A. Hannun et al. profile →
  3. Sphingolipids and their metabolism in physiology and disease
    2017 1.4k citations Yusuf A. Hannun, Lina M. Obeid profile →
  4. An Overview of Sphingolipid Metabolism: From Synthesis to Breakdown
    2010 861 citations Christopher Gault, Lina M. Obeid et al. Advances in experimental medicine and biology profile →
  5. The Ceramide-centric Universe of Lipid-mediated Cell Regulation: Stress Encounters of the Lipid Kind
    2002 743 citations Yusuf A. Hannun, Lina M. Obeid Journal of Biological Chemistry profile →
  6. Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation.
    1991 564 citations Lina M. Obeid, Yusuf A. Hannun et al. Journal of Biological Chemistry profile →
  7. Many Ceramides
    2011 471 citations Yusuf A. Hannun, Lina M. Obeid Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Lina M. Obeid United States 94 26.4k 7.4k 5.3k 3.3k 2.4k 291 30.5k
Sheldon Milstien United States 88 20.5k 0.8× 7.3k 1.0× 4.8k 0.9× 3.7k 1.1× 1.8k 0.7× 237 26.6k
Timothy Hla United States 99 23.6k 0.9× 6.7k 0.9× 4.0k 0.8× 4.8k 1.4× 1.3k 0.5× 245 35.3k
Sarah Spiegel United States 113 38.6k 1.5× 14.0k 1.9× 6.8k 1.3× 6.2k 1.9× 2.9k 1.2× 399 44.9k
Junken Aoki Japan 80 16.0k 0.6× 4.6k 0.6× 3.1k 0.6× 2.7k 0.8× 1.3k 0.5× 396 21.5k
Richard Kolesnick United States 75 18.2k 0.7× 3.4k 0.5× 3.6k 0.7× 3.2k 1.0× 1.2k 0.5× 149 23.8k
Joseph Avruch United States 95 29.1k 1.1× 8.6k 1.2× 3.2k 0.6× 3.8k 1.1× 1.8k 0.7× 189 38.2k
Masahiko Negishi United States 96 15.7k 0.6× 4.9k 0.7× 2.8k 0.5× 1.8k 0.5× 1.9k 0.8× 514 33.2k
Brian A. Hemmings Switzerland 102 33.2k 1.3× 7.2k 1.0× 3.0k 0.6× 3.8k 1.1× 1.8k 0.7× 313 42.4k
Daria Mochly‐Rosen United States 88 17.3k 0.7× 2.7k 0.4× 3.9k 0.7× 1.6k 0.5× 2.0k 0.8× 319 26.1k
Brendan D. Manning United States 62 22.0k 0.8× 3.5k 0.5× 4.5k 0.8× 3.5k 1.0× 3.6k 1.5× 118 30.9k

Countries citing papers authored by Lina M. Obeid

Since Specialization
Citations

This map shows the geographic impact of Lina M. Obeid's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lina M. Obeid with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lina M. Obeid more than expected).

Fields of papers citing papers by Lina M. Obeid

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lina M. Obeid. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lina M. Obeid. The network helps show where Lina M. Obeid may publish in the future.

Co-authorship network of co-authors of Lina M. Obeid

This figure shows the co-authorship network connecting the top 25 collaborators of Lina M. Obeid. A scholar is included among the top collaborators of Lina M. Obeid based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lina M. Obeid. Lina M. Obeid is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Stith, Jeffrey L., et al.. (2023). Targeting sphingosine kinase 1 in p53KO thymic lymphoma. The FASEB Journal. 37(11). e23247–e23247. 1 indexed citations
2.
Yi, Jae Kyo, Ruijuan Xu, Lina M. Obeid, et al.. (2022). Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn2+-dependent amidases. PLoS ONE. 17(9). e0271540–e0271540. 3 indexed citations
3.
Clarke, Christopher J., Jeffrey L. Stith, Justin M. Snider, et al.. (2021). Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides. Cell Death and Disease. 12(1). 27–27. 12 indexed citations
4.
Truman, Jean‐Philip, Christian Ruiz, Emily Montal, et al.. (2021). 1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase. Journal of Lipid Research. 63(1). 100154–100154. 12 indexed citations
5.
Hannun, Yusuf A., et al.. (2021). Loss of sphingosine kinase 1 increases lung metastases in the MMTV-PyMT mouse model of breast cancer. PLoS ONE. 16(5). e0252311–e0252311. 2 indexed citations
6.
Truman, Jean‐Philip, et al.. (2021). Sphingosine kinase 1 downregulation is required for adaptation to serine deprivation. The FASEB Journal. 35(2). e21284–e21284. 9 indexed citations
7.
Mileva, Izolda, et al.. (2019). Quantifying 1-deoxydihydroceramides and 1-deoxyceramides in mouse nervous system tissue. Prostaglandins & Other Lipid Mediators. 141. 40–48. 11 indexed citations
8.
Ren, Jihui, Essa M. Saied, Justin M. Snider, et al.. (2018). Tsc3 regulates SPT amino acid choice in Saccharomyces cerevisiae by promoting alanine in the sphingolipid pathway. Journal of Lipid Research. 59(11). 2126–2139. 13 indexed citations
9.
Dupre, Tess V., Mark A. Doll, Parag P. Shah, et al.. (2017). Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury. Journal of Lipid Research. 58(7). 1439–1452. 41 indexed citations
10.
Lu, Songjian, Chunhui Cai, Gonghong Yan, et al.. (2016). Signal-Oriented Pathway Analyses Reveal a Signaling Complex as a Synthetic Lethal Target for p53 Mutations. Cancer Research. 76(23). 6785–6794. 3 indexed citations
11.
Hernandez‐Corbacho, María José, Daniel Canals, Mohamad M. Adada, et al.. (2015). Tumor Necrosis Factor-α (TNFα)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death. Journal of Biological Chemistry. 290(42). 25356–25373. 61 indexed citations
12.
Shamseddine, A., et al.. (2015). Ceramide and sphingosine-1-phosphate in cancer, two faces of the sphinx. Translational Cancer Research. 4(5). 484–499. 20 indexed citations
13.
Mullen, Thomas D., Yusuf A. Hannun, & Lina M. Obeid. (2012). Ceramide synthases at the centre of sphingolipid metabolism and biology. Biochemical Journal. 441(3). 789–802. 414 indexed citations
14.
Lee, Alvin, Rebecca Roylance, Jil Sander, et al.. (2011). CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid‐specific cancer cell death through autophagy induction. The Journal of Pathology. 226(3). 482–494. 52 indexed citations
15.
Gault, Christopher, Lina M. Obeid, & Yusuf A. Hannun. (2010). An Overview of Sphingolipid Metabolism: From Synthesis to Breakdown. Advances in experimental medicine and biology. 688. 1–23. 861 indexed citations breakdown →
16.
Anelli, Viviana, et al.. (2007). Sphingosine Kinase 1 Is Up-regulated during Hypoxia in U87MG Glioma Cells. Journal of Biological Chemistry. 283(6). 3365–3375. 127 indexed citations
17.
Szulc, Zdzisław M., Lina M. Obeid, Y A Hannun, & Alicia Bielawska. (2007). Highly Efficient and Regioselective Phosphorylation of Sphingolipids by Phase-Trans fer Catalysis. Polish Journal of Chemistry. 81(11). 1899–1909. 3 indexed citations
18.
Thompson, Christopher R. L., Shankar S. Iyer, Rebecca L. VanOosten, et al.. (2005). Sphingosine Kinase 1 (SK1) Is Recruited to Nascent Phagosomes in Human Macrophages: Inhibition of SK1 Translocation by Mycobacterium tuberculosis. The Journal of Immunology. 174(6). 3551–3561. 86 indexed citations
19.
Dbaibo, Ghassan, Marina Y. Pushkareva, Rima Rachid, et al.. (1998). p53-dependent ceramide response to genotoxic stress.. Journal of Clinical Investigation. 102(2). 329–339. 143 indexed citations
20.
Smyth, Miriam J., et al.. (1997). Ceramide: A Novel Lipid Mediator of Apoptosis. Advances in pharmacology. 41. 133–154. 56 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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