Can E. Senkal

4.1k citations

37 papers · 3.4k indexed · 1 hit paper · h-index 26

Co-authors: Besim Öğretmen Jacek Bielawski Suriyan Ponnusamy Yusuf A. Hannun Lina M. Obeid Shanmugam Panneer Selvam Sahar A. Saddoughi Salih Gencer
Topics: Sphingolipid Metabolism and Signaling (32 papers)Endoplasmic Reticulum Stress and Disease (9 papers)Lipid metabolism and biosynthesis (7 papers)
Cited by: Cell Biology Biochemistry Molecular Biology
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry Journal of Clinical Oncology
Partner nations: United States Türkiye Egypt

In The Last Decade

Can E. Senkal

36 papers receiving 3.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

2012 432 citations Can E. Senkal, Wenhui Jiang et al. profile →

Peers

Countries citing papers authored by Can E. Senkal

Since Specialization

Citations

This map shows the geographic impact of Can E. Senkal's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Can E. Senkal with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Can E. Senkal more than expected).

Fields of papers citing papers by Can E. Senkal

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Can E. Senkal. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Can E. Senkal. The network helps show where Can E. Senkal may publish in the future.

Co-authorship network of co-authors of Can E. Senkal

This figure shows the co-authorship network connecting the top 25 collaborators of Can E. Senkal. A scholar is included among the top collaborators of Can E. Senkal based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Can E. Senkal. Can E. Senkal is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Targeting ceramide synthases for the development of new antifungals 2025 ·Structure ·(unknown),Nívea Pereira de Sá,(unknown),(unknown),(unknown),(unknown),(unknown),A. Zhong,Can E. Senkal,Yusuf A. Hannun,Iwao Ojima,John P. Mallamo,(unknown),Maurizio Del Poeta	0
2	Glycosylation of ceramide synthase 6 is required for its activity 2024 ·Journal of Lipid Research ·(unknown),(unknown),Can E. Senkal	1
3	Cholesterol-dependent homeostatic regulation of very long chain sphingolipid synthesis 2023 ·The Journal of Cell Biology ·Yeongho Kim,(unknown),Can E. Senkal,Christopher G. Burd	3
4	The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation 2023 ·Cell Reports ·(unknown),(unknown),Johnny Stiban,(unknown),(unknown),(unknown),(unknown),Yusuf A. Hannun,Lina M. Obeid,Can E. Senkal	17
5	Targeting defective sphingosine kinase 1 in Niemann–Pick type C disease with an activator mitigates cholesterol accumulation 2020 ·Journal of Biological Chemistry ·Jason Newton,Elisa N.D. Palladino,Cynthia Weigel,Michael Maceyka,Markus H. Gräler,Can E. Senkal,Ricardo D. Enriz,(unknown),Josef Jampílek,Santiago Lima,Sheldon Milstien,Sarah Spiegel	19
6	Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways 2018 ·Journal of Biological Chemistry ·Pamela A. Young,Can E. Senkal,(unknown),Trisha J. Grevengoed,(unknown),Liyang Zhao,Amanda E. Crunk,Eric L. Klett,Joachim Füllekrug,Lina M. Obeid,Rosalind Coleman	73
7	A novel role for ceramide synthase 6 in mouse and human alcoholic steatosis 2017 ·The FASEB Journal ·(unknown),Jason Correnti,Amanke Oranu,Annie Lin,Victoria Scott,(unknown),Jürgen Beck,Emma E. Furth,(unknown),Can E. Senkal,Lina M. Obeid,Rotonya M. Carr	26
8	Sphingolipids in mitochondria 2016 ·Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ·María José Hernandez‐Corbacho,Mohamed Salama,Daniel Canals,Can E. Senkal,Lina M. Obeid	101
9	Tumor Necrosis Factor-α (TNFα)-induced Ceramide Generation via Ceramide Synthases Regulates Loss of Focal Adhesion Kinase (FAK) and Programmed Cell Death 2015 ·Journal of Biological Chemistry ·María José Hernandez‐Corbacho,Daniel Canals,Mohamad M. Adada,(unknown),Can E. Senkal,Jae Kyo Yi,Cungui Mao,Chiara Luberto,Yusuf A. Hannun,Lina M. Obeid	61
10	Targeting Sphingosine Kinase Induces Apoptosis and Tumor Regression for KSHV-Associated Primary Effusion Lymphoma 2013 ·Molecular Cancer Therapeutics ·Zhiqiang Qin,Lu Dai,Jimena Trillo-Tinoco,Can E. Senkal,Wenxue Wang,(unknown),(unknown),Luis Del Valle,Paulo C. Rodrı́guez,Erik K. Flemington,Christina Voelkel‐Johnson,Charles D. Smith,Besim Öğretmen,Chris Parsons	54
11	Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis 2012 ·EMBO Molecular Medicine ·Sahar A. Saddoughi,Salih Gencer,Yuri K. Peterson,Katherine E. Ward,Archana Mukhopadhyay,Joshua J. Oaks,Jacek Bielawski,Zdzisław M. Szulc,Raquela J. Thomas,Shanmugam Panneer Selvam,Can E. Senkal,Elizabeth Garrett‐Mayer,Ryan De Palma,(unknown),Angen Liu,Amyn A. Habib,Robert V. Stahelin,Danilo Perrotti,Besim Öğretmen	223
12	Concerted functions of HDAC1 and microRNA‐574‐5p repress alternatively spliced ceramide synthase 1 expression in human cancer cells 2011 ·EMBO Molecular Medicine ·Marisa Meyers‐Needham,Suriyan Ponnusamy,Salih Gencer,Wenhui Jiang,Raquela J. Thomas,Can E. Senkal,Besim Öğretmen	53
13	Alteration of Ceramide Synthase 6/C16-Ceramide Induces Activating Transcription Factor 6-mediated Endoplasmic Reticulum (ER) Stress and Apoptosis via Perturbation of Cellular Ca2+ and ER/Golgi Membrane Network 2011 ·Journal of Biological Chemistry ·Can E. Senkal,Suriyan Ponnusamy,Yefim Manevich,Marisa Meyers‐Needham,Sahar A. Saddoughi,(unknown),Paul Dent,Jacek Bielawski,Besim Öğretmen	118
14	Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells 2009 ·Oncogene ·Shai White‐Gilbertson,Thomas D. Mullen,Can E. Senkal,Ping Lü,Besim Öğretmen,Lina M. Obeid,Christina Voelkel‐Johnson	132
15	A New Mixed-Backbone Oligonucleotide against Glucosylceramide Synthase Sensitizes Multidrug-Resistant Tumors to Apoptosis 2009 ·PLoS ONE ·Gauri A. Patwardhan,Qian-Jin Zhang,Dongmei Yin,Vineet K. Gupta,Jianxiong Bao,Can E. Senkal,Besim Öğretmen,Myles C. Cabot,Girish V. Shah,Paul W. Sylvester,S. Michal Jazwinski,Yu Liu	43
16	Direct interaction between the inhibitor 2 and ceramide via sphingolipid‐protein binding is involved in the regulation of protein phosphatase 2A activity and signaling 2008 ·The FASEB Journal ·Archana Mukhopadhyay,Sahar A. Saddoughi,Pengfei Song,Iyad Sultan,Suriyan Ponnusamy,Can E. Senkal,C.F. Snook,Hugh Arnold,Rosalie C. Sears,(unknown),Besim Öğretmen	177
17	Alterations of Ceramide/Sphingosine 1-Phosphate Rheostat Involved in the Regulation of Resistance to Imatinib-induced Apoptosis in K562 Human Chronic Myeloid Leukemia Cells 2007 ·Journal of Biological Chemistry ·Yusuf Baran,(unknown),Can E. Senkal,Ufuk Gündüz,Jacek Bielawski,Lina M. Obeid,Besim Öğretmen	188
18	Potent Antitumor Activity of a Novel Cationic Pyridinium-Ceramide Alone or in Combination with Gemcitabine against Human Head and Neck Squamous Cell Carcinomas in Vitro and in Vivo 2006 ·Journal of Pharmacology and Experimental Therapeutics ·Can E. Senkal,Suriyan Ponnusamy,Michael J. Rossi,Kamala Sundararaj,Zdzisław M. Szulc,Jacek Bielawski,Alicja Bielawska,(unknown),Bengü Çobanoğlu,Serap Köybaşı,Debajyoti Sinha,Terry A. Day,Lina M. Obeid,Yusuf A. Hannun,Besim Öğretmen	80
19	Protein Kinase C-induced Activation of a Ceramide/Protein Phosphatase 1 Pathway Leading to Dephosphorylation of p38 MAPK 2006 ·Journal of Biological Chemistry ·Kazuyuki Kitatani,Jolanta Idkowiak‐Baldys,Jacek Bielawski,Tarek A. Taha,Russell W. Jenkins,Can E. Senkal,Besim Öğretmen,Lina M. Obeid,Yusuf A. Hannun	57
20	Defects in Cell Growth Regulation by C18:0-Ceramide and Longevity Assurance Gene 1 in Human Head and Neck Squamous Cell Carcinomas 2004 ·Journal of Biological Chemistry ·Serap Köybaşı,Can E. Senkal,Kamala Sundararaj,Stefka D. Spassieva,Jacek Bielawski,Walid Osta,Terry A. Day,James C. Jiang,S. Michal Jazwinski,Yusuf A. Hannun,Lina M. Obeid,Besim Öğretmen	194

About Can E. Senkal

Can E. Senkal is a scholar working on Biochemistry, Cell Biology and Molecular Biology, having authored 37 papers that have together received 3.4k indexed citations. Recurring topics across this work include Sphingolipid Metabolism and Signaling (32 papers), Endoplasmic Reticulum Stress and Disease (9 papers) and Lipid metabolism and biosynthesis (7 papers). The work is most often cited by research in Cell Biology (810 citations), Biochemistry (350 citations) and Molecular Biology (2.9k citations). Can E. Senkal has collaborated with scholars based in United States, Türkiye and Egypt. Frequent co-authors include Besim Öğretmen, Jacek Bielawski, Suriyan Ponnusamy, Yusuf A. Hannun, Lina M. Obeid, Shanmugam Panneer Selvam, Sahar A. Saddoughi, Salih Gencer, Zdzisław M. Szulc and Marisa Meyers‐Needham. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Oncology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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