Lee‐Yuan Liu‐Chen

7.4k citations

152 papers · 6.2k indexed · h-index 46

Cellular and Molecular Neuroscience top 0.2%
- Neuropeptides and Animal Physiology 118
- Neuroscience and Neuropharmacology Research 14
- Neurotransmitter Receptor Influence on Behavior 13
Molecular Biology top 1%
- Receptor Mechanisms and Signaling 108
- Pharmacological Receptor Mechanisms and Effects 51
- Protein Kinase Regulation and GTPase Signaling 5
Toxicology top 1%
Physiology top 2%
- Pain Mechanisms and Treatments 25
Anesthesiology and Pain Medicine top 2%
Animal Science and Zoology
- Pharmacological Effects and Assays 6

Co-authors: Chongguang Chen Peng Huang Michael A. Moskowitz Jianguo LiWei XuYu‐Lin Wang Jinmin Zhu A. Cowan
Cited by: Cellular and Molecular Neuroscience Molecular Biology Toxicology
Journals: Science (1 paper)Proceedings of the National Academy of Sciences (1 paper)Journal of Biological Chemistry (12 papers)
Partner nations: United States Germany Austria

In The Last Decade

Lee‐Yuan Liu‐Chen

150 papers receiving 6.0k citations

Peers

Countries citing papers authored by Lee‐Yuan Liu‐Chen

Since Specialization

Citations

This map shows the geographic impact of Lee‐Yuan Liu‐Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lee‐Yuan Liu‐Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lee‐Yuan Liu‐Chen more than expected).

Fields of papers citing papers by Lee‐Yuan Liu‐Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lee‐Yuan Liu‐Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lee‐Yuan Liu‐Chen. The network helps show where Lee‐Yuan Liu‐Chen may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Lee‐Yuan Liu‐Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lee‐Yuan Liu‐Chen Line = papers co-authored together Lee‐Yuan Liu‐Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Pharmacological characterization of the novel selective kappa opioid receptor agonists 10-Iodo-Akuammicine and 10-Bromo-akuammicine in mice Neuropharmacology ·Kathryn Bland,Chongguang Chen,Peng Huang,Conrad K. Ho,Trevor Howe,Katrina Ocampo,Pingwei Zhao,Simone M. Creed,Joseph Noel-Torres,Andrew P. Riley,Lee‐Yuan Liu‐Chen	2025	0
2	NCP, a Dual Kappa and Mu Opioid Receptor Agonist, Is a Potent Analgesic Against Inflammatory Pain without Reinforcing or Aversive Properties Journal of Pharmacology and Experimental Therapeutics ·Peng Huang,Conrad K. Ho,Danni Cao,Saadet Inan,Scott M. Rawls,Mengchu Li,Boshi Huang,Piyusha P. Pagare,E. Andrew Townsend,Justin L. Poklis,Matthew S. Halquist,Matthew L. Banks,Yan Zhang,Lee‐Yuan Liu‐Chen	2024	2
3	Reactivation of cocaine contextual memory engages mechanistic target of rapamycin/S6 kinase 1 signaling Frontiers in Pharmacology ·Xiangdang Shi,Eva von Weltin,Emma Fitzsimmons,Chau Do,Carolina Caban Rivera,Chongguang Chen,Lee‐Yuan Liu‐Chen,Ellen M. Unterwald	2022	6
4	Characterization of a Knock-In Mouse Line Expressing a Fusion Protein of κ Opioid Receptor Conjugated with tdTomato: 3-Dimensional Brain Imaging via CLARITY eNeuro ·Chongguang Chen,Alex H. Willhouse,Peng Huang,Nora Ko,Yujun Wang,Bin Xu,Lan Huang,Brigitte L. Kieffer,Mary F. Barbe,Lee‐Yuan Liu‐Chen	2020	39
5	In vivo brain GPCR signaling elucidated by phosphoproteomics Science ·Jeffrey J. Liu,Kirti Sharma,Luca Zangrandi,Chongguang Chen,Sean J. Humphrey,Yi-Ting Chiu,Mariana Spetea,Lee‐Yuan Liu‐Chen,Christoph Schwarzer,Matthias Mann	2018	98
6	Two short-acting kappa opioid receptor antagonists (zyklophin and LY2444296) exhibited different behavioral effects from the long-acting antagonist norbinaltorphimine in mouse anxiety tests Neuroscience Letters ·Peng Huang,T. V. Yakovleva,Jane V. Aldrich,Julia Tunis,C. B. Wynn Parry,Lee‐Yuan Liu‐Chen	2016	14
7	l-Isocorypalmine reduces behavioral sensitization and rewarding effects of cocaine in mice by acting on dopamine receptors Drug and Alcohol Dependence ·Wei Xu,Yujun Wang,Zhongze Ma,Yi-Ting Chiu,Peng Huang,Khampaseuth Rasakham,Ellen M. Unterwald,David Y.W. Lee,Lee‐Yuan Liu‐Chen	2013	50
8	Mephedrone (‘bath salt’) elicits conditioned place preference and dopamine-sensitive motor activation Drug and Alcohol Dependence ·Renata Lisek,Wei Xu,Ekaterina Yuvasheva,Yi-Ting Chiu,Allen B. Reitz,Lee‐Yuan Liu‐Chen,Scott M. Rawls	2012	96
9	Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analogues Bioorganic & Medicinal Chemistry Letters ·Cécile Béguin,Justin S. Potuzak,Wei Xu,Lee‐Yuan Liu‐Chen,John M. Streicher,Chad E. Groer,Laura Bohn,William A. Carlezon,Bruce M. Cohen	2011	22
10	Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior Proceedings of the National Academy of Sciences ·Stephen D. Mague,Carolina Isiegas,Peng Huang,Lee‐Yuan Liu‐Chen,Caryn Lerman,Julie A. Blendy	2009	138
11	Hyperlocomotion and paw tremors are two highly quantifiable signs of SR141716-precipitated withdrawal from delta9-tetrahydrocannabinol in C57BL/6 mice Neuroscience Letters ·Peng Huang,Lee‐Yuan Liu‐Chen,Ellen M. Unterwald,Alan Cowan	2009	20
12	In vivo trafficking of endogenous opioid receptors Life Sciences ·Yu‐Lin Wang,Elisabeth J. Van Bockstaele,Lee‐Yuan Liu‐Chen	2008	26
13	Modification of the furan ring of salvinorin A: Identification of a selective partial agonist at the kappa opioid receptor Bioorganic & Medicinal Chemistry ·Cécile Béguin,Katharine K. Duncan,Thomas A. Munro,Douglas M. Ho,Wei Xu,Lee‐Yuan Liu‐Chen,William A. Carlezon,Bruce M. Cohen	2008	27
14	Synthesis and in vitro pharmacological studies of new C(4)-modified salvinorin A analogues Bioorganic & Medicinal Chemistry Letters ·David Y.W. Lee,Minsheng He,Lee‐Yuan Liu‐Chen,Yu‐Lin Wang,Jianguo Li,Wei Xu,Zhongze Ma,William A. Carlezon,Bruce M. Cohen	2006	23
15	Synthesis and in vitro evaluation of salvinorin A analogues: Effect of configuration at C(2) and substitution at C(18) Bioorganic & Medicinal Chemistry Letters ·Cécile Béguin,Michele R. Richards,Jianguo Li,Yu‐Lin Wang,Wei Xu,Lee‐Yuan Liu‐Chen,William A. Carlezon,Bruce M. Cohen	2006	56
16	New neoclerodane diterpenoids isolated from the leaves of Salvia divinorum and their binding affinities for human κ opioid receptors Bioorganic & Medicinal Chemistry ·David Y.W. Lee,Zhongze Ma,Lee‐Yuan Liu‐Chen,Yulin Wang,Yong Chen,William A. Carlezon,Bruce M. Cohen	2005	54
17	Synthesis and in vitro pharmacological studies of C(4) modified salvinorin A analogues Bioorganic & Medicinal Chemistry Letters ·David Y.W. Lee,Minsheng He,Leelakrishna Kondaveti,Lee‐Yuan Liu‐Chen,Zhongze Ma,Yu‐Lin Wang,Yong Chen,Jianguo Li,Cécile Béguin,William A. Carlezon,Bruce M. Cohen	2005	28
18	Determination of the Amino Acid Residue Involved in [3H]β-Funaltrexamine Covalent Binding in the Cloned Rat µ Opioid Receptor Journal of Biological Chemistry ·Chongguang Chen,Jinling Yin,J. Kim de Riel,Renée L. DesJarlais,Luca F. Raveglia,Jinmin Zhu,Lee‐Yuan Liu‐Chen	1996	74
19	Antisense oligodeoxynucleotides against μ- or κ-opioid receptors block agonist-induced body temperature changes in rats Brain Research ·Xiaohong Chen,E. Geller,J. Kim de Riel,Lee‐Yuan Liu‐Chen,Martin W. Adler	1995	22
20	Reversible and irreversible binding of beta-funaltrexamine to mu, delta and kappa opioid receptors in guinea pig brain membranes. Journal of Pharmacology and Experimental Therapeutics ·S. William Tam,Lee‐Yuan Liu‐Chen	1986	47

About Lee‐Yuan Liu‐Chen

Lee‐Yuan Liu‐Chen is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Physiology, having authored 152 papers that have together received 6.2k indexed citations. Recurring topics across this work include Neuropeptides and Animal Physiology (118 papers), Receptor Mechanisms and Signaling (108 papers), Pharmacological Receptor Mechanisms and Effects (51 papers), Pain Mechanisms and Treatments (25 papers), Neuroscience and Neuropharmacology Research (14 papers), Neurotransmitter Receptor Influence on Behavior (13 papers), Pharmacological Effects and Assays (6 papers) and Protein Kinase Regulation and GTPase Signaling (5 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (4.3k citations), Molecular Biology (4.1k citations) and Toxicology (171 citations). Lee‐Yuan Liu‐Chen has collaborated with scholars based in United States, Germany and Austria. Frequent co-authors include Chongguang Chen, Peng Huang, Michael A. Moskowitz, Jianguo Li, Wei Xu, Yu‐Lin Wang, Jinmin Zhu, A. Cowan, Christopher S. Chen and David Y.W. Lee. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

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