Christopher S. Chen

67.3k total citations · 25 hit papers
403 papers, 51.5k citations indexed

About

Christopher S. Chen is a scholar working on Cell Biology, Biomedical Engineering and Molecular Biology. According to data from OpenAlex, Christopher S. Chen has authored 403 papers receiving a total of 51.5k indexed citations (citations by other indexed papers that have themselves been cited), including 181 papers in Cell Biology, 174 papers in Biomedical Engineering and 106 papers in Molecular Biology. Recurrent topics in Christopher S. Chen's work include Cellular Mechanics and Interactions (165 papers), 3D Printing in Biomedical Research (142 papers) and Cell Adhesion Molecules Research (40 papers). Christopher S. Chen is often cited by papers focused on Cellular Mechanics and Interactions (165 papers), 3D Printing in Biomedical Research (142 papers) and Cell Adhesion Molecules Research (40 papers). Christopher S. Chen collaborates with scholars based in United States, United Kingdom and Canada. Christopher S. Chen's co-authors include Donald E. Ingber, Celeste M. Nelson, George M. Whitesides, Dana M. Pirone, Kiran Bhadriraju, Brendon M. Baker, Milan Mrksich, Sui Huang, John L. Tan and Daniel M. Cohen and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Christopher S. Chen

392 papers receiving 50.7k citations

Hit Papers

Geometric Control of Cell Life and Death 1997 2026 2006 2016 1997 2004 2003 2012 2009 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Geometric Control of Cell Life and Death
    1997 3.8k citations Christopher S. Chen et al. profile →
  2. Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment
    2004 3.4k citations Dana M. Pirone, Celeste M. Nelson et al. profile →
  3. Cells lying on a bed of microneedles: An approach to isolate mechanical force
    2003 1.5k citations John L. Tan, Joe Tien et al. Proceedings of the National Academy of Sciences profile →
  4. Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues
    2012 1.5k citations Michael T. Yang, Brendon M. Baker et al. profile →
  5. Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix
    2009 1.5k citations Daniel M. Cohen, Christopher S. Chen et al. profile →
  6. Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues
    2012 1.4k citations Brendon M. Baker, Christopher S. Chen Journal of Cell Science profile →
  7. Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure
    1997 1.3k citations Christopher S. Chen et al. Proceedings of the National Academy of Sciences profile →
  8. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics
    2010 1.2k citations Michael T. Yang, Christopher S. Chen et al. Nature profile →
  9. Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels
    2013 951 citations Daniel M. Cohen, Christopher S. Chen et al. profile →
  10. Mechanical regulation of cell function with geometrically modulated elastomeric substrates
    2010 867 citations Michael T. Yang, Ravi A. Desai et al. profile →
  11. Emergent patterns of growth controlled by multicellular form and mechanics
    2005 687 citations Celeste M. Nelson, Ronald P. Jean et al. Proceedings of the National Academy of Sciences profile →
  12. Mechanotransduction in development: a growing role for contractility
    2008 640 citations Christopher S. Chen et al. profile →
  13. Micropatterned Surfaces for Control of Cell Shape, Position, and Function
    1998 566 citations Christopher S. Chen et al. profile →
  14. Mechanical tugging force regulates the size of cell–cell junctions
    2010 554 citations Zhijun Liu, John L. Tan et al. Proceedings of the National Academy of Sciences profile →
  15. Nanopattern-induced changes in morphology and motility of smooth muscle cells
    2005 509 citations Christopher S. Chen et al. profile →
  16. Measurement of mechanical tractions exerted by cells in three-dimensional matrices
    2010 501 citations Daniel M. Cohen, Christopher S. Chen et al. profile →
  17. Versatile, Fully Automated, Microfluidic Cell Culture System
    2007 488 citations Dana M. Pirone, Christopher S. Chen et al. profile →
  18. Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments
    2015 461 citations Brendon M. Baker, Mahmut Selman Sakar et al. profile →
  19. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy
    2015 425 citations William J. Polacheck, Christopher S. Chen et al. profile →
  20. Fluid Shear Stress on Endothelial Cells Modulates Mechanical Tension across VE-Cadherin and PECAM-1
    2013 398 citations Mark T. Breckenridge, Christopher S. Chen et al. profile →
  21. Mechanical regulation of glycolysis via cytoskeleton architecture
    2020 396 citations Linqing Li, Christopher S. Chen et al. Nature profile →
  22. Measuring cell-generated forces: a guide to the available tools
    2016 360 citations William J. Polacheck, Christopher S. Chen profile →
  23. Vascular Tissue Engineering: Progress, Challenges, and Clinical Promise
    2018 359 citations Christopher S. Chen et al. profile →
  24. MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools
    2019 277 citations Christopher S. Chen et al. profile →
  25. Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions
    2012 224 citations Christopher S. Chen et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Christopher S. Chen United States 111 27.4k 22.0k 13.7k 7.0k 6.0k 403 51.5k
Dennis E. Discher United States 95 21.0k 0.8× 18.2k 0.8× 18.3k 1.3× 14.2k 2.0× 5.6k 0.9× 317 58.5k
Paul A. Janmey United States 105 14.2k 0.5× 24.3k 1.1× 14.1k 1.0× 5.5k 0.8× 3.1k 0.5× 430 47.0k
Donald E. Ingber United States 155 40.4k 1.5× 26.6k 1.2× 29.0k 2.1× 6.9k 1.0× 7.5k 1.2× 454 88.9k
Adam J. Engler United States 53 14.3k 0.5× 11.5k 0.5× 6.6k 0.5× 6.0k 0.9× 4.9k 0.8× 143 27.2k
Roger D. Kamm United States 100 16.5k 0.6× 7.5k 0.3× 9.8k 0.7× 4.2k 0.6× 5.3k 0.9× 460 35.9k
Valerie M. Weaver United States 77 11.0k 0.4× 15.6k 0.7× 12.4k 0.9× 3.4k 0.5× 2.8k 0.5× 184 36.6k
Benjamin Geiger Israel 102 7.4k 0.3× 23.8k 1.1× 18.8k 1.4× 2.6k 0.4× 2.4k 0.4× 342 43.4k
Kenneth M. Yamada United States 140 10.0k 0.4× 25.4k 1.2× 28.8k 2.1× 4.3k 0.6× 5.0k 0.8× 701 71.9k
H. Lee Sweeney United States 81 9.2k 0.3× 10.6k 0.5× 18.2k 1.3× 3.8k 0.5× 3.8k 0.6× 279 34.6k
David Mooney United States 152 51.4k 1.9× 11.8k 0.5× 19.3k 1.4× 34.9k 5.0× 18.7k 3.1× 656 102.1k

Countries citing papers authored by Christopher S. Chen

Since Specialization
Citations

This map shows the geographic impact of Christopher S. Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher S. Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher S. Chen more than expected).

Fields of papers citing papers by Christopher S. Chen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher S. Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher S. Chen. The network helps show where Christopher S. Chen may publish in the future.

Co-authorship network of co-authors of Christopher S. Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Christopher S. Chen. A scholar is included among the top collaborators of Christopher S. Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Christopher S. Chen. Christopher S. Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Ching, Terry, Jessica L. Teo, Anish Vasan, et al.. (2025). TapeTech microfluidic connectors: adhesive tape-enabled solution for organ-on-a-chip system integration. Lab on a Chip. 25(6). 1474–1488. 4 indexed citations
2.
Kim, Suntae, et al.. (2024). 3D printing assisted surface patterning process on acrylated hydrogels for contact guidance of fibroblasts. Colloids and Surfaces B Biointerfaces. 242. 114099–114099. 4 indexed citations
3.
Low, Stewart A., et al.. (2024). Targeted Delivery of Abaloparatide to Spinal Fusion Site Accelerates Fusion Process in Rats. Biomedicines. 12(3). 612–612.
4.
Sundaram, Subramanian, Isabel M. Bjørge, Alex Lammers, et al.. (2024). Sacrificial capillary pumps to engineer multiscalar biological forms. Nature. 636(8042). 361–367. 20 indexed citations
5.
Mani, Hamdi, P.F. Marsh, Richard Al Hadi, et al.. (2024). A 4-mW 2.2–6.9 GHz LNA in 16 nm FinFET Technology for Cryogenic Applications. IEEE Microwave and Wireless Technology Letters. 34(12). 1351–1354. 2 indexed citations
6.
Sutherland, Bryan P., et al.. (2022). Mechanical response of cardiac microtissues to acute localized injury. American Journal of Physiology-Heart and Circulatory Physiology. 323(4). H738–H748. 17 indexed citations
7.
Tefft, Juliann B., Christopher S. Chen, & Jeroen Eyckmans. (2021). Reconstituting the dynamics of endothelial cells and fibroblasts in wound closure. APL Bioengineering. 5(1). 16102–16102. 33 indexed citations
8.
Kutys, Matthew L., William J. Polacheck, Michaela Welch, et al.. (2020). Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform. Nature Communications. 11(1). 3377–3377. 39 indexed citations
9.
Alimperti, Stella, Teodelinda Mirabella, William J. Polacheck, et al.. (2017). Three-dimensional biomimetic vascular model reveals a RhoA, Rac1, and N -cadherin balance in mural cell–endothelial cell-regulated barrier function. Proceedings of the National Academy of Sciences. 114(33). 8758–8763. 95 indexed citations
10.
Mui, Keeley L., Christopher S. Chen, & Richard K. Assoian. (2016). The mechanical regulation of integrin–cadherin crosstalk organizes cells, signaling and forces. Journal of Cell Science. 129(6). 1093–1100. 238 indexed citations
11.
Hood, David A., Liam D. Tryon, Anna Vainshtein, et al.. (2015). Exercise and the Regulation of Mitochondrial Turnover. Progress in molecular biology and translational science. 135. 99–127. 33 indexed citations
12.
Bagley, Alexander F., Ruth Scherz‐Shouval, Peter A. Galie, et al.. (2015). Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors. Cancer Research. 75(16). 3255–3267. 27 indexed citations
13.
Wang, Chong, Brendon M. Baker, Christopher S. Chen, & Martin A. Schwartz. (2013). Endothelial Cell Sensing of Flow Direction. Arteriosclerosis Thrombosis and Vascular Biology. 33(9). 2130–2136. 232 indexed citations
14.
Cohen, Daniel M., Ravi A. Desai, Mark T. Breckenridge, et al.. (2013). Activation of beta 1 but not beta 3 integrin increases cell traction forces. FEBS Letters. 587(6). 763–769. 67 indexed citations
15.
Sakar, Mahmut Selman, Devin Neal, Thomas Boudou, et al.. (2012). Formation and Optogenetic Control of 3D Engineered Skeletal Muscle Bioactuators. Europe PMC (PubMed Central). 226 indexed citations
16.
Lin, Yi‐Chia, et al.. (2012). Probing cellular traction forces with magnetic nanowires and microfabricated force sensor arrays. Nanotechnology. 23(7). 75101–75101. 31 indexed citations
17.
Liu, Zhijun, John L. Tan, Daniel M. Cohen, et al.. (2010). Mechanical tugging force regulates the size of cell–cell junctions. Proceedings of the National Academy of Sciences. 107(22). 9944–9949. 554 indexed citations breakdown →
18.
Ruiz, Sami Alom & Christopher S. Chen. (2008). Emergence of Patterned Stem Cell Differentiation Within Multicellular Structures. Stem Cells. 26(11). 2921–2927. 334 indexed citations
19.
Nelson, Celeste M., Ronald P. Jean, John L. Tan, et al.. (2005). Emergent patterns of growth controlled by multicellular form and mechanics. Proceedings of the National Academy of Sciences. 102(33). 11594–11599. 687 indexed citations breakdown →
20.
Tan, John L., Joe Tien, Dana M. Pirone, et al.. (2003). Cells lying on a bed of microneedles: An approach to isolate mechanical force. Proceedings of the National Academy of Sciences. 100(4). 1484–1489. 1540 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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