Brigitte L. Kieffer

25.4k total citations · 3 hit papers
281 papers, 18.9k citations indexed

About

Brigitte L. Kieffer is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Physiology. According to data from OpenAlex, Brigitte L. Kieffer has authored 281 papers receiving a total of 18.9k indexed citations (citations by other indexed papers that have themselves been cited), including 248 papers in Cellular and Molecular Neuroscience, 210 papers in Molecular Biology and 64 papers in Physiology. Recurrent topics in Brigitte L. Kieffer's work include Neuropeptides and Animal Physiology (199 papers), Receptor Mechanisms and Signaling (184 papers) and Neurotransmitter Receptor Influence on Behavior (80 papers). Brigitte L. Kieffer is often cited by papers focused on Neuropeptides and Animal Physiology (199 papers), Receptor Mechanisms and Signaling (184 papers) and Neurotransmitter Receptor Influence on Behavior (80 papers). Brigitte L. Kieffer collaborates with scholars based in France, Canada and United States. Brigitte L. Kieffer's co-authors include Claire Gavériaux‐Ruff, Katia Befort, Hans W. D. Matthes, Rafaël Maldonado, Dominique Filliol, Pierre-Éric Lutz, Frédéric Simonin, Jérôme A. J. Becker, Emmanuel Darcq and Julie Le Merrer and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Brigitte L. Kieffer

279 papers receiving 18.6k citations

Hit Papers

3 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the µ-opioid-receptor gene

1996 1.4k citations Hans W. D. Matthes, Frédéric Simonin et al. profile →
Reward Processing by the Opioid System in the Brain

2009 756 citations Jérôme A. J. Becker, Katia Befort et al. profile →
Mice deficient for δ- and μ-opioid receptors exhibit opposing alterations of emotional responses

2000 550 citations Dominique Filliol, Hans W. D. Matthes et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Brigitte L. Kieffer France	73	13.5k	11.0k	4.7k	1.6k	1.5k	281	18.9k
Charles Chavkin United States	73	13.7k 1.0×	10.9k 1.0×	3.2k 0.7×	1.6k 1.0×	1.1k 0.7×	197	17.5k
MacDonald J. Christie Australia	68	11.0k 0.8×	9.5k 0.9×	5.6k 1.2×	1.7k 1.0×	2.0k 1.3×	234	17.3k
Mark J. Millan France	70	10.4k 0.8×	7.0k 0.6×	5.0k 1.1×	2.7k 1.7×	2.7k 1.8×	284	19.3k
Ferdinando Nicoletti Italy	81	13.6k 1.0×	10.5k 1.0×	4.3k 0.9×	2.2k 1.3×	1.5k 1.0×	535	24.6k
Raul R. Gainetdinov Russia	79	17.8k 1.3×	15.1k 1.4×	2.2k 0.5×	3.4k 2.0×	1.3k 0.9×	333	28.2k
Michael W. Salter Canada	74	12.3k 0.9×	9.4k 0.9×	11.0k 2.3×	2.0k 1.2×	2.2k 1.5×	180	25.1k
Lars Terenius Sweden	82	18.0k 1.3×	12.9k 1.2×	8.0k 1.7×	1.9k 1.2×	1.5k 1.0×	386	26.9k
Min Zhuo Canada	82	13.2k 1.0×	8.5k 0.8×	10.3k 2.2×	6.2k 3.8×	1.9k 1.2×	359	23.3k
Horace H. Loh United States	74	13.7k 1.0×	12.2k 1.1×	4.8k 1.0×	672 0.4×	878 0.6×	502	18.9k
Gavril W. Pasternak United States	79	14.2k 1.1×	12.3k 1.1×	7.1k 1.5×	591 0.4×	932 0.6×	331	19.8k

Countries citing papers authored by Brigitte L. Kieffer

Since Specialization

Citations

This map shows the geographic impact of Brigitte L. Kieffer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brigitte L. Kieffer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brigitte L. Kieffer more than expected).

Fields of papers citing papers by Brigitte L. Kieffer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brigitte L. Kieffer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brigitte L. Kieffer. The network helps show where Brigitte L. Kieffer may publish in the future.

Co-authorship network of co-authors of Brigitte L. Kieffer

This figure shows the co-authorship network connecting the top 25 collaborators of Brigitte L. Kieffer. A scholar is included among the top collaborators of Brigitte L. Kieffer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brigitte L. Kieffer. Brigitte L. Kieffer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kuzmanovic, Bojana, Sofia Lundh, A. Claßen, et al.. (2025). Thalamic opioids from POMC satiety neurons switch on sugar appetite. Science. 387(6735). 750–758. 5 indexed citations

Kieffer, Brigitte L., et al.. (2024). Model of negative affect induced by withdrawal from acute and chronic morphine administration in male mice. Scientific Reports. 14(1). 9767–9767. 8 indexed citations

Smith, Alexander C.W., Samuel W. Centanni, Lauren Wills, et al.. (2024). A master regulator of opioid reward in the ventral prefrontal cortex. Science. 384(6700). eadn0886–eadn0886. 9 indexed citations

Allain, Florence, et al.. (2023). Advances in the characterization of negative affect caused by acute and protracted opioid withdrawal using animal models. Neuropharmacology. 232. 109524–109524. 15 indexed citations

Karatas, Meltem, Vincent Noblet, Thomas Bienert, et al.. (2021). Mapping the living mouse brain neural architecture: strain-specific patterns of brain structural and functional connectivity. Brain Structure and Function. 226(3). 647–669. 8 indexed citations

Otsu, Yo, Emmanuel Darcq, Katarzyna Pietrajtis, et al.. (2019). Control of aversion by glycine-gated GluN1/GluN3A NMDA receptors in the adult medial habenula. Science. 366(6462). 250–254. 69 indexed citations

Mann, Anika, Lionel Moulédous, Carine Froment, et al.. (2019). Agonist-selective NOP receptor phosphorylation correlates in vitro and in vivo and reveals differential post-activation signaling by chemically diverse agonists. Science Signaling. 12(574). 31 indexed citations

Mechling, Anna E., Thomas Bienert, Hsu‐Lei Lee, et al.. (2017). Remodeling of Sensorimotor Brain Connectivity in Gpr88 -Deficient Mice. Brain Connectivity. 7(8). 526–540. 22 indexed citations

Kieffer, Brigitte L., et al.. (2013). κ-Opioid Receptors in the Central Amygdala Regulate Ethanol Actions at Presynaptic GABAergic Sites. Journal of Pharmacology and Experimental Therapeutics. 346(1). 130–137. 44 indexed citations

10.

Nguyen, Alexander T., Paul Marquez, Abdul Hamid, et al.. (2012). The rewarding action of acute cocaine is reduced in β-endorphin deficient but not in μ opioid receptor knockout mice. European Journal of Pharmacology. 686(1-3). 50–54. 23 indexed citations

11.

Nozaki, Chihiro, Angela Maria Vergnano, Dominique Filliol, et al.. (2011). Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit. Nature Neuroscience. 14(8). 1017–1022. 107 indexed citations

12.

Pfaff, Donald W. & Brigitte L. Kieffer. (2008). Molecular and biophysical mechanisms of arousal, alertness, and attention. 23 indexed citations

13.

Gavériaux‐Ruff, Claire & Brigitte L. Kieffer. (2007). Conditional gene targeting in the mouse nervous system: Insights into brain function and diseases. Pharmacology & Therapeutics. 113(3). 619–634. 98 indexed citations

14.

Scherrer, Grégory, Petra Tóth, Dominique Filliol, et al.. (2006). Knockin mice expressing fluorescent δ-opioid receptors uncover G protein-coupled receptor dynamics in vivo. Proceedings of the National Academy of Sciences. 103(25). 9691–9696. 186 indexed citations

15.

Contet, Candice, Claire Gavériaux‐Ruff, Audrey Matifas, et al.. (2005). Dissociation of Analgesic and Hormonal Responses to Forced Swim Stress Using Opioid Receptor Knockout Mice. Neuropsychopharmacology. 31(8). 1733–1744. 64 indexed citations

16.

Morin‐Surun, Marie‐Pierre, Éliane Boudinot, Hans W. D. Matthes, et al.. (2001). Respiratory function in adult mice lacking the µ‐opioid receptor: role of δ‐receptors. European Journal of Neuroscience. 13(9). 1703–1710. 24 indexed citations

17.

Bigoni, Raffaella, A. Rizzi, Daniela Rizzi, et al.. (2000). In vitro pharmacological profile of peptide III-BTD. Life Sciences. 68(2). 233–239. 11 indexed citations

18.

Kovoor, Abraham, et al.. (1997). μ and δ Opioid Receptors Are Differentially Desensitized by the Coexpression of β-Adrenergic Receptor Kinase 2 and β-Arrestin 2 in Xenopus Oocytes. Journal of Biological Chemistry. 272(44). 27605–27611. 125 indexed citations

19.

Simonin, Frédéric, Claire Gavériaux‐Ruff, Katia Befort, et al.. (1995). kappa-Opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system.. Proceedings of the National Academy of Sciences. 92(15). 7006–7010. 181 indexed citations

20.

Kieffer, Brigitte L., Diane Black, & C. Hirth. (1993). 32P Labeled Opioid Peptides with High Affinity for the δ-Opioid Receptor. Analytical Biochemistry. 215(1). 1–8. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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