Trevor Howe

2.6k citations

24 papers · 1.2k indexed · h-index 13

Impact in

Cellular and Molecular Neuroscience top 5%
- Neuroscience and Neuropharmacology Research
Pharmacology top 2%
- Pharmacogenetics and Drug Metabolism

Papers in

Physiology 2
Spectroscopy 6
- Molecular spectroscopy and chirality 3

Co-authors: Claire Mackie Emanuele Carosati Benoît De Boeck Gabriele Cruciani Kantharaj Ethirajulu Riccardo Vianello Darryle D. Schoepp Joseph P. Tizzano
Journals: Journal of Medicinal Chemistry (7 papers)Tetrahedron Letters (2 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)Current Topics in Medicinal Chemistry (1 paper)Drug Discovery Today (1 paper)
Partner nations: United Kingdom United States Switzerland

In The Last Decade

Trevor Howe

22 papers receiving 1.2k citations

Peers

Countries citing papers authored by Trevor Howe

Since Specialization

Citations

This map shows the geographic impact of Trevor Howe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Trevor Howe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Trevor Howe more than expected).

Fields of papers citing papers by Trevor Howe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Trevor Howe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Trevor Howe. The network helps show where Trevor Howe may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Trevor Howe, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Trevor Howe Line = papers co-authored together Trevor Howe links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Pharmacological characterization of the novel selective kappa opioid receptor agonists 10-Iodo-Akuammicine and 10-Bromo-akuammicine in mice Neuropharmacology ·Huasheng Wang, Chongguang Chen, Peng Huang, 具春植, Trevor Howe, N. Sandhya, Pingwei Zhao, 陽一塔間, Harriet Slade, Andrew P. Riley, Lee‐Yuan Liu‐Chen	2025	0
2	Design and synthesis of a library of chemokine antagonists Bioorganic & Medicinal Chemistry Letters ·Gurdip Bhalay, J.-C. M. Tran, Mohammed Shahid Akhlaq, Carolina Bordonaro, David Beer, Zarin Brown, Steven J. Charlton, Andrew R. Dunstan, Michael Cullen, Peter Gedeck, Angela Glen, Trevor Howe, Thomas H. Keller, Juliet Leighton-Davies, 赵则永, Clive McCarthy, Amber Rahmat, Charles Owen, 戈海青, Elizabeth M. Rosethorne	2011	4
3	A comparison of ligand based virtual screening methods and application to corticotropin releasing factor 1 receptor Journal of Molecular Graphics and Modelling ·Gary Tresadern, Dr Bindu Menon K, Trevor Howe	2009	55
4	Optimizing the Performance of In Silico ADMET General Models According to Local Requirements: MARS Approach. Solubility Estimations As Case Study Journal of Chemical Information and Modeling ·Julen Oyarzábal, Joaquı́n Pastor, Trevor Howe	2009	9
5	Novel Approach for Chemotype Hopping Based on Annotated Databases of Chemically Feasible Fragments and a Prospective Case Study: New Melanin Concentrating Hormone Antagonists Journal of Medicinal Chemistry ·Julen Oyarzábal, Trevor Howe, Jesús Alcázar, José Ignacio Andrés, Rosa M. Álvarez, Frank M. Dautzenberg, Laura Iturrino, Sonia Martı́nez, Ilse Van der Linden	2009	23
6	Assessment of Additive/Nonadditive Effects in Structure−Activity Relationships: Implications for Iterative Drug Design Journal of Medicinal Chemistry ·Yogendra Patel, Valerie J. Gillet, Trevor Howe, Joaquı́n Pastor, Julen Oyarzábal, Peter Willett	2008	40
7	Data reduction and representation in drug discovery Drug Discovery Today ·Trevor Howe, 日月橋場, Patrick Marichal, Tyler D. Scott, Isaac Alzate	2006	15
8	CGH2466, a combined adenosine receptor antagonist, p38 mitogen‐activated protein kinase and phosphodiesterase type 4 inhibitor with potent in vitro and in vivo anti‐inflammatory activities British Journal of Pharmacology ·Alexandre Trifilieff, Thomas H. Keller, Neil J. Press, Trevor Howe, Peter Gedeck, David Beer, Christoph Walker	2005	16
9	MetaSite: Understanding Metabolism in Human Cytochromes from the Perspective of the Chemist Journal of Medicinal Chemistry ·Gabriele Cruciani, Emanuele Carosati, Benoît De Boeck, Kantharaj Ethirajulu, Claire Mackie, Trevor Howe, Riccardo Vianello	2005	354
10	New Highly Potent and Selective Adenosine A3 Receptor Antagonists Current Topics in Medicinal Chemistry ·Neil J. Press, Thomas H. Keller, Pamela Tranter, David Beer, Ken Jones, Valenzuela S, Richard Heng, Christine A. Lewis, Trevor Howe, Peter Gedeck	2004	14
11	Application of Non-Parametric Regression to Quantitative Structure–Activity Relationships Bioorganic & Medicinal Chemistry ·Jonathan D. Hirst, Paula Straile-Costa, Trevor Howe, Lewis Whitehead	2002	6
12	Dimerization of G-Protein-Coupled Receptors Journal of Medicinal Chemistry ·Manisha Mistry, Christopher Higgs, Richard E. Smith, Robert P. Bywater, Christopher R. Snell, Paul D. Scott, Graham Upton, Trevor Howe, Christopher A. Reynolds	2001	116
13	Design, Synthesis, and Proposed Active Site Binding Analysis of Monocyclic 2-Azetidinone Inhibitors of Prostate Specific Antigen Journal of Medicinal Chemistry ·Robert M. Adlington, Jack E. Baldwin, Gerald W. Becker, Beining Chen, Tatyana E. Sushina, M. Dionigi, Róbert Hermann, Trevor Howe, William McCoull, Ann M. McNulty, Blake Lee Neubauer, Gareth J. Pritchard	2001	61
14	Design, Synthesis, and Pharmacological Characterization of (+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY354740): A Potent, Selective, and Orally Active Group 2 Metabotropic Glutamate Receptor Agonist Possessing Anticonvulsant and Anxiolytic Properties Journal of Medicinal Chemistry ·James A. Monn, Matthew J. Valli, Steven M. Massey, Rebecca A. Wright, Craig R. Salhoff, Bryan G. Johnson, Trevor Howe, Charles A. Alt, André Steffens, Roger L. Robey, JoAnn McDonald, Joseph P. Tizzano, Mary Jeanne Kallman, David R. Helton, Darryle D. Schoepp	1997	337
15	Design and synthesis of novel monocyclic β-lactam inhibitors of prostate specific antigen Bioorganic & Medicinal Chemistry Letters ·Robert M. Adlington, Jack E. Baldwin, Beining Chen, M. Dionigi, William McCoull, Gareth J. Pritchard, Trevor Howe, Gerald W. Becker, Róbert Hermann, Ann M. McNulty, Blake Lee Neubauer	1997	63
16	ChemInform Abstract: Design and Synthesis of Novel Monocyclic β‐Lactam Inhibitors of Prostate Specific Antigen. ChemInform ·Robert M. Adlington, Jack E. Baldwin, С.С. Москвичев, Stephen Cooper, William McCoull, Gareth J. Pritchard, Trevor Howe, Gerald W. Becker, Róbert Hermann, Hafizah Putri Salim, Blake Lee Neubauer	1997	2
17	Preliminary investigation into the purification, NMR analysis, and molecular modelling of chondroitin sulphate epitopes Carbohydrate Research ·Zlochin Mark, Stephen Carney, Trevor Howe	1994	7
18	Acetylation of a heterocyclic enaminonitrile: Unambiguous structural assignment using NMR methods Journal of Heterocyclic Chemistry ·C. P. Dell, Trevor Howe, Snežana Ivković	1994	4
19	Long-range substituent effects on conformational equilibria Journal of Molecular Structure ·Otto Exner, Michael J. Cook, Trevor Howe	1990	2
20	Conformational interactions between a phenyl ring and a side-chain halide substituent: A 1H NMR and molecular mechanics study of some 2-aryl-1-halopropanes Spectrochimica Acta Part A Molecular Spectroscopy ·Michael J. Cook, Trevor Howe	1990	1

About Trevor Howe

Trevor Howe is a scholar working on Physiology, Spectroscopy, Computational Theory and Mathematics, Organic Chemistry and Toxicology, having authored 24 papers that have together received 1.2k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (5 papers), Receptor Mechanisms and Signaling (5 papers), Chemical Synthesis and Analysis (4 papers), Monoclonal and Polyclonal Antibodies Research (4 papers), Neuroscience and Neuropharmacology Research (3 papers), Synthesis of β-Lactam Compounds (3 papers), Molecular spectroscopy and chirality (3 papers) and Protein Structure and Dynamics (2 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (393 citations), Pharmacology (177 citations), Computational Theory and Mathematics (286 citations), Organic Chemistry (308 citations) and Molecular Biology (697 citations). Trevor Howe has collaborated with scholars based in United Kingdom, United States and Switzerland. Frequent co-authors include Claire Mackie, Emanuele Carosati, Benoît De Boeck, Gabriele Cruciani, Kantharaj Ethirajulu, Riccardo Vianello, Darryle D. Schoepp, Joseph P. Tizzano, Craig R. Salhoff and Bryan G. Johnson. Their work appears in journals such as Journal of Medicinal Chemistry, Tetrahedron Letters, Bioorganic & Medicinal Chemistry Letters, Current Topics in Medicinal Chemistry and Drug Discovery Today.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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